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Orientation in upper gastrointestinal endoscopy—the only way is up

World Journal of Gastrointestinal Endoscopy 2023年第3期15卷 146-152页

作者： Arun Sivananthan Georgina Kerry Ara Darzi Kinesh patel nisha patel Department of Surgery and Cancer Imperial College LondonLondon W21NYUnited Kingdom Liver Intensive Care Unit King’s College Hospital NHS Foundation TrustLondon SE59RSUnited Kingdom Gastroenterology Chelsea and Westminster NHS Foundation TrustLondon SW109NHUnited Kingdom

BACKGROUND Oesophagogastroduodenoscopy is the gold standard investigation for the upper gastrointestinal(UGI)*** during endoscopy is challenging and United Kingdom training focusses on technical competence and procedural *** reported location of UGI pathologies is crucial to post-endoscopic *** To evaluate endoscopists’ability to spatially orientate themselves within the UGI *** A cross sectional descriptive study elicited,using an anonymised survey,the ability of endoscopists to orientate themselves within the UGI *** primary outcome was percentage of correct answers from all surveyed;secondary outcomes were percentage of correct answers from experienced vs novice ***’sχ2 test was applied to compare *** Of 188 respondents,86 were experienced endoscopists having completed over 1000 endoscopies.44.4%of respondents correctly identified the anterior stomach and 47.3%correctly identified the posterior of the second part of the duodenum(D2).Experienced endoscopists were significantly more likely than novice to identify the anterior stomach correctly[61.6%vs 31.3%,X2(1,n=188)=11.10,P=0.001].There was no significant difference between the two groups in identifying the posterior of *** The majority of endoscopists surveyed were unable to identify key landmarks within the UGI *** orientation appears to improve with experience yet there are some areas still not well *** has potential considerable impact on post-endoscopic management of patients with posterior duodenal ulcers being more likely to perforate and associated with a higher rebleeding *** suggest the development of a consensus statement on endoscopic description.

关键词： Endoscopy Orientation Upper gastrointestinal Gastric cancer Duodenal ulcer

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Meta-analysis comparing differing methods of endoscopic therapy for colorectal lesions

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World Journal of Meta-Analysis 2016年第2期4卷 44-54页

作者： nisha patel James Alexander Hutan Ashrafian Thanos Athanasiou Ara Darzi Julian Teare Department of Gastroenterology St Mary’s HospitalImperial College London Department of Surgery and Cancer St Mary’s HospitalImperial College London

AIM： To compare the outcomes of endoscopic mucosal resection （EMR） and endoscopic submucosal dissection （ESD） of colorectal ***： An electronic systematic literature search of four computerized databases was performed in July 2014 identifying studies reporting the outcomes of colorectal ESD and EMR. The primary outcome measures were en-bloc resection rate, endoscopic clearance rate and lesion recurrence rate of the patients followed up. The secondary outcome was the complication rate （including bleeding, perforation and surgery post EMR or ESD rate）. Statistical pooling and random effects modelling of the studies calculating risk difference, heterogeneity and assessment of bias and quality were ***： Six observational studies reporting the outcomes of 1324 procedures were included. The en-bloc resection rate was 50% higher in the ESD group than in the EMR group （95%CI： 0.17-0.83, P 〈 0.0001, I2 = 99.7%）. Endoscopic clearance rates were also signifcantly higher in the ESD group （95%CI： -0.06-0.02, P 〈 0.0001, I2 = 92.5%）. The perforation rate was 7% higher in the ESD group than the EMR group （95%CI： 0.05-0.09, P 〉 0.05, I2 = 41.1%） and the rate of recurrence was 50% higher in the EMR group than in the ESD group （95%CI： 0.20-0.79, P 〈 0.001, I2 = 99.5%）. Heterogeneity remained consistent when subgroup analysis of high quality studies was performed （with the exception of piecemeal resection rate）, and overall effect sizes remained unchanged for all ***： ESD demonstrates higher en-bloc resection rates and lower recurrence rates compared to colorectal EMR. Differences in outcomes may beneft from increased assessment through well-designed comparative studies.

关键词： Colorectal Colonic polyp Endoscopic mucosal resection Endoscopic submucosal dissection Colorectal cancer

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Real-World Safety and Performance of Saline Nasal Spray Products for Nasal Cleansing and Reducing Obstruction of the Nasal Cavity

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Open Journal of Respiratory Diseases 2023年第4期13卷 65-79页

作者： Mathieu M. Albasser Gary Smith Mariane Ballerini Fernandes nisha patel Petr Novak Martina Hagen GSK Consumer Healthcare SARL a Haleon company Nyon Switzerland Haleon Weybridge Surrey UK GSK Kingston upon Thames London UK Haleon Prague Czech Republic

Background and Objectives: Three post-marketing clinical follow-up studies were performed in Europe to confirm the safety and performance of four nonprescription, nasal cleansing medical devices: Otrivin Sea Water (OSW) pressurized spray, OSW with aloe vera (OSWAV), Otrisal 0.74% NaCl Metered-Dose Spray (MDS), and Prorhinel spray. Material and Methods: Observational, single-arm, retrospective studies consisting of a single online questionnaire were performed between July 2021 and December 2021. Eligible participants were adults who used the device or supervised use of the device in a participant under 18 years of age within 6 months of completing the questionnaire. Demographics, safety, and device performance were assessed. Results: Based on questionnaires submitted on OSW (n = 556), OSWAV (n = 555), Otrisal MDS (n = 555), and Prorhinel (n = 555), proportions of users who reported safety events were 1.8% for OSW, 2.3% for OSWAV, 1.4% for Otrisal MDS, and 2.0% for Prorhinel. Proportions of users who indicated they were satisfied or very satisfied with device performance ranged from 72.0% - 89.0% across all devices. Device performance for all products was also supported for additional preventative and symptomatic uses through exploratory analyses. Conclusions and Significance: These data confirm device safety and performance of OSW, OSWAV, Otrisal MDS, and Prorhinel for their intended uses.

关键词： Saline Solution Sodium Chloride Common Cold Allergens Postmarketing Product Surveillance

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A rare co-occurrence of spontaneous pneumomediastinum,pneumothorax,and pneumoperitoneum:Macklin effect

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World Journal of Emergency Medicine 2024年第3期15卷 246-248页

作者： Renaldo Pavrey Nikita Makwana nisha Das Centre for Accident and Emergency Medicine Nanavati Max Super Specialty HospitalMumbai 400050India

Spontaneous pneumomediastinum (SPM) is characterized by free air or gas located within the mediastinum that is not associated with any noticeable cause,such as chest trauma,intrathoracic infections,surgery,other organ... 详细信息

关键词： rupture trauma infections

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Community perspectives on the effectiveness of watershed management institutions in the Himalayas

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Journal of Mountain Science 2024年第4期21卷 1119-1139页

作者： nisha SILWAL Nabin DHUNGANA Rajan SUBEDI Suraj UPADHAYA Chun-Hung LEE Natural Resources Conservation Nepal(NRCN) ChitwanP.O.Box 44200Nepal Department of Natural Resources and Environmental Studies College of Environmental StudiesNational Dong Hwa UniversityHualien 97401Chinese Taipei Institute of Forestry Tribhuvan UniversityPokharaP.O.Box 43Nepal School of Agriculture and Natural Resources Kentucky State UniversityFrankfortKY 40601USA Himalayan Conservation and Research Institute DolpaP.O.Box 21400Nepal

The sustainability of environmental management initiatives,such as watershed management programs,relies on the presence of effective institutions at the watershed ***,there needs to be more empirical evidence from evaluating the effectiveness of watershed-level ***,this study presents a pioneering effort to evaluate the effectiveness of Nepal’s first watershed conservation committee at the watershed scale,focusing on the case of the Khageri Khola watershed in Central *** study involved conducting a household survey,key informant interviews,focus group discussions,and field observations to collect and analyze the *** analysis,index value calculation,and chi-square statistics were then employed to summarize the results regarding local respondents’perceptions of twelve institutional characteristics,their rationalities,and their association with socio-demographic *** results reveal that the watershed conservation committee was perceived as performing well in managing the ***,good interaction,appropriate scale,technical,environmental,social,organizational,and government rationality were perceived as highly effective,with an average index value of less than *** contrast,clarity of objectives and economic rationality showed moderate effectiveness,with an average index value ranging from 0.36 to ***,the results suggested that adaptiveness,compliance capacity,and financial rationality merit increased attention,intending to improve their ***,the results showed the association of socio-demographics with respondents’perceptions of various indicators of institutional characteristics and their ***,the study provides valuable insights for policymakers,researchers,and development practitioners charged with designing sustainable and effective programs and *** enhance the effectiveness and sustainability of watershed management programs,we recommen

关键词： Watershed Watershed institutions Indicators Institutional characteristics Rationalities Nepal.

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Navigating emotional challenges:A journey with patients undergoing chemotherapy

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World Journal of Clinical Oncology 2024年第9期15卷 1132-1135页

作者： nisha Mani Pandey Pooja Ramakant Department of Geriatric Mental Health King George's Medical UniversityLucknow 226003India Department of Endocrine Surgery King Georges Medical UniversityLucknow 226003India

A recent article reported that cancer patients with subthreshold depression are more likely to develop major depression within a *** regression analysis revealed that regular exercise was a protective factor against cancerrelated fatigue,whereas advanced age,radiotherapy,pain,and low hemoglobin were risk factors for cancer-related fatigue.A limitation of this study was the lack of methodological details about leukemia patients receiving depressive treatment at a specific *** assessment,behavioral modification plans,communication,destressing techniques,and educational plans may help chemotherapy patients manage emotional issues and reduce ***,these strategies can inspire patients to create,facilitate their treatment,and help them to remain healthy.

关键词： Leukemia patients Cancer patients Emotional distress Subthreshold depression Chemotherapy

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Promoting Ethical Sensitivity in Nursing Education:A Systematic Review of Case Study-Based Health Education

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Journal of Clinical and Nursing Research 2024年第4期8卷 22-29页

作者： Jinyi Tang Santhna Letchmi Panduragan Fatimah Yahya nisha Nambiar Faculty of Nursing Lincoln University CollegeMalaysia

Introduction: Nursing ethical sensitivity refers to a nurse’s capacity for thoughtful consideration of ethical issues when faced with dilemmas. In the nursing domain, ethical dilemmas arise when nurses face challenges in making sound ethical decisions during clinical practice. These challenges may stem from conflicts between personal values and professional responsibilities. Methodology: Articles downloaded from Pub Med, CNKI, and Google Scholar were reviewed. Results: After rigorous screening, a meticulous analysis was conducted, encompassing 10 articles and involving a substantial cohort of 2863 participants. Existing literature revealed variations in the ethical dilemmas faced by nurses across different departments. The ethical sensitivity of nurses also varies, with higher ethical sensitivity correlating with stronger empathetic abilities. Zhen et al. classified the causes of ethical dilemmas into four main categories: (1) Ethical dilemmas arising from personal reasons of nursing students;(2) Ethical dilemmas stemming from the actions of teachers;(3) Ethical dilemmas triggered by patients;(4) Ethical dilemmas resulting from miscellaneous reasons. Conclusion: According to literature findings, nursing ethical sensitivity was positively linked to the nurse’s ethical decision-making ability. A case study-oriented teaching program has proven effective in enhancing ethical sensitivity among nursing students.

关键词： Ethical sensitivity Ethical dilemma Case study education Nursing ethical sensitivity scale Influencing factors Nursing student

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Real-World Safety and Performance of Saline Nasal Spray Products for Nasal Cleansing and Reducing Obstruction of the Nasal Cavity

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Open Journal of Respiratory Diseases（呼吸病期刊） 2023年第4期

作者： Mathieu M.Albasser Gary Smith Mariane Ballerini Fernandes nisha patel Petr Novak Martina Hagen

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外语学习者心流研究:理论、主题与设计

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外语教学 2024年第3期45卷 6-13页

作者：徐锦芬赵妮莎华中科技大学外国语学院重庆医科大学外国语学院

本文采用范围综述方法,检索并筛选有关外语学习者心流研究的SSCI和CSSCI来源期刊论文共34篇,从理论视角、研究主题及研究设计三个方面进行评述。结果表明:1)现有研究以心流理论为主,部分研究采用多种理论视角,但跨学科理论资源与外语学... 详细信息

本文采用范围综述方法,检索并筛选有关外语学习者心流研究的SSCI和CSSCI来源期刊论文共34篇,从理论视角、研究主题及研究设计三个方面进行评述。结果表明:1)现有研究以心流理论为主,部分研究采用多种理论视角,但跨学科理论资源与外语学习实证研究融合度不够;2)研究主题集中在外语学习者心流的成因和状态上,较少关注心流对学业成就及积极情绪的影响;3)被试多为大学英语学习者,背景多元化不足,存在抽样偏差问题;4)技术赋能对外语学习者心流体验有促进作用,但研究设计呈同质化倾向,缺乏深入的质性数据解释;5)以横向研究为主,缺乏对心流体验的动态跟踪。

关键词：外语学习者心流理论视角研究主题研究设计

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OFDI对工业绿色全要素生产率的影响机制--基于两阶段Super-SBM-Malmquist指数模型的分析

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中国管理科学 2024年第5期32卷 229-240页

作者：申晨辛雅儒贾妮莎冯锐浙江理工大学经济管理学院浙江杭州310018 陕西师范大学国际商学院陕西西安710119 广州大学经济与统计学院广东广州510006

中国对外直接投资(outward foreign direct investment,OFDI)在推动中国经济与世界经济的深度融合、形成国内国际双循环发展新格局中有着举足轻重的作用。本文基于中国2005-2017年30个省份的面板数据,运用非期望产出的两阶段Super-SBM网... 详细信息

中国对外直接投资(outward foreign direct investment,OFDI)在推动中国经济与世界经济的深度融合、形成国内国际双循环发展新格局中有着举足轻重的作用。本文基于中国2005-2017年30个省份的面板数据,运用非期望产出的两阶段Super-SBM网络DEA模型以及结合全局ML生产率指数测算了中国各省份的工业绿色全要素生产率、生产效率和治污效率,并从理论和实证上考察了中国OFDI对三大效率的影响。研究发现:OFDI对三大效率的影响均表现为稳健的U型非线性关系;从作用机制看,短期内,OFDI对三大效率的抑制作用主要由于规模效应所致,长期内,OFDI对三大效率的促进作用主要通过结构效应和技术效应实现;从异质性视角看,我国东部和西部地区OFDI与三大效率呈显著的U型关系,中部地区的OFDI作用不显著,“一带一路”沿线省份的OFDI产生的正向效应早于非沿线省份。

关键词：对外直接投资(OFDI) 绿色全要素生产率(GTFP) 两阶段Super-SBM网络模型全局参比的Malmquist-Luenberger(GML)指数

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