检索结果-南通市图书馆

Asian Journal of Urology 2022年第3期9卷 318-328页

作者： Chinna Babu Dracham Narendra kumar Santosh kumar Arun Elangovan Budhi Singh Yadav Ravimohan S.Mavuduru Anupam Lal Pramod K.gupta Rakesh Kapoor Department of Radiotherapy&Oncology PGIMERChandigarhIndia Department of Urology PGIMERChandigarhIndia Department of Radiodiagnosis PGIMERChandigarhIndia Department of Biostatistics PGIMERChandigarhIndia

Objective:Conservative approaches in muscle-invasive bladder cancer(MIBC)have been evolved to avoid aggressive surgery,but are limited to elderly,frail,and patients medically unfit for *** study aimed to assess the response rate of neoadjuvant chemotherapy(NACT)before radiotherapy(RT)in MIBC ***:Forty patients with urothelial carcinoma of stage T2-T4a,N0,M0 were enrolled between November 2013 and November 2015,and treated with three cycles of NACT with ***-NACT response was assessed using Response Evaluation Criteria in Solid Tumors(RECIST)*** who achieved complete response(CR)and partial response(PR)>50%were treated with radical RT,and those who had PR50%or CR,and were treated with ***(12.5%)patients who had PR<50%,SD,or PD underwent *** patients who received radiation showed CR after 6 *** follow-up was 43 months(range:10-66 months)and median overall survival(OS)was not ***-year OS,local control,and disease-free survival were 70.1%,60.9%,50.6%,respectively,and 50%of patients preserved their functioning ***-year OS rate was 88.9%in patients who achieved CR to NACT,73.1%in patients with PR≥50%and 40%in patients with PR<50%.Conclusion:NACT followed by RT provides a high probability of local response with bladder preservation in CR *** use of this treatment regimen in carefully selected patients may omit the need for morbid surgery.

关键词： Bladder preservation Neoadjuvant chemotherapy Radiotherapy Muscle-invasive bladder cancer

Population structure analysis and determination of neurotoxin content in a set of grass pea (Lathyrus sativus L.) accessions of Bangladesh origin

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The Crop Journal 2018年第4期6卷 435-442页

作者： Priyanka gupta Sripada M. Udupa Debjyoti Sen gupta Jitendra kumar Shiv kumar International Center for Agricultural Research in the Dry Areas Rabat Institute Rabat Morocco Department of Plant Sciences North Dakota State University Fargo ND 58105 USA ICAR-Indian Institute of Pulses Research Kanpur Uttar Pradesh 208024 India

Grass pea(Lathyrus sativus L.) is a crop that is considered one of the more resilient to climate change. With protein-rich seeds and leaves, it has strong potential as human food as well as animal feed and fodder. However, genetic improvement in this crop remains stagnant owing to the poor characterization of its genetic resources. In this study, we characterized 118 accessions of grass pea with 18 EST-SSR markers. A total of 118 accessions, 101 of L. sativus(100 cultivated accessions from Bangladesh and one wild accession) and 17 wild accessions of other Lathyrus species, were used. A total of 67 alleles were detected, with an average of 3.72 alleles per locus and average polymorphism information content of 0.52. A dissimilarity matrix was formed and hierarchical cluster analysis performed using the UPGMA method grouped genotypes into four main clusters. Cluster analysis based on the genetic dissimilarity revealed a clear grouping of the 100 cultivated and 18 wild accessions into four main groups. Group I consisted of 20 accessions with high β-N-oxalyl-L-α,β-diaminopropionic acid(β-ODAP) concentration. Of these 20 accessions, 17 were wild accessions. Only one wild accession(L. cicera) was clustered in group II, which contained 35 accessions. Most of the group II accessions contained low β-ODAP. Group III was represented by 34 accessions, many of them with high β-ODAP. Group IV consisted of 29 accessions, a few of which had very high β-ODAP concentrations. Analysis of molecular variance of the microsatellite data showed significantly higher values of molecular variance between(83%) than within(17%) populations. These characterized accessions will be useful in grass pea breeding programs.

关键词：草豌豆蛋白质植物学气候

Two-Dimensional Lattice Boltzmann Model for Droplet Impingement and Breakup in Low Density Ratio Liquids

在线全文

学校读者我要写书评

暂无评论

Communications in Computational Physics 2011年第8期10卷 767-784页

作者： Amit gupta Ranganathan kumar Department of Mechanical Engineering Indian Institute of TechnologyNew DelhiIndia 110016 Department of Mechanical Materials and Aerospace EngineeringUniversity of Central FloridaOrlandoFL 32816USA

A two-dimensional lattice Boltzmann model has been employed to simulate the impingement of a liquid drop on a dry *** a range of Weber number,Reynolds number and low density ratios,multiple phases leading to breakup have been *** analytical solution for breakup as function of Reynolds and Weber number based on the conservation of energy is shown to match well with the *** the moment breakup occurs,the spread diameter is maximum;it increases with Weber number and reaches an asymptotic value at a density ratio of *** breakup is found to be more viable for the case when the wall is non-wetting or neutral as compared to a wetting *** breakup,the distance between the daughter droplets is much higher for the case with a non-wetting wall,which illustrates the role of the surface interactions in the outcome of the impact.

关键词： Lattice Boltzmann droplet impingement spread factor breakup

Y chromosome microdeletions in azoospermic patients with Klinefelter's syndrome

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Asian Journal of Andrology 2006年第1期8卷 81-88页

作者： Anurag Mitra Rima Dada Rajeev kumar Narmada Prasad gupta Kiran Kucheria Satish kumar gupta Gamete Antigen Laboratory National Institute of ImmunologyAruna Asaf Ali MargNew Delhi 110067India Department of Anatomy Department of Urology All India Institute of Medical SciencesAnsari NagarNew Delhi 110029India

Aim： To study the occurrence of Y chromosome microdeletions in azoospermic patients with Klinefelter＇s syndrome （KFS）. Methods： Blood and semen samples were collected from azoospermic patients with KFS （n = 14） and a control group of men of proven fertility （n = 13）. Semen analysis was done according to World Health Organization （WHO） guidelines. Blood samples were processed for karyotyping, fluorescent in situ hybridization （FISH） and measurement of plasma follicle stimulating hormone （FSH） by radioimmunoassay. To determine Y chromosome microdeletions, polymerase chain reaction （PCR） of 16 sequence tagged sites （STS） and three genes （DFFRY, XKRY and RBM1 Y） was performed on isolated genomic DNA. Testicular fine needle aspiration cytology （FNAC） was done in selected cases. Results： Y chromosome microdeletions spanning the azoospermia factor （AZF）a and AZFb loci were found in four of the 14 azoospermic patients with KFS. Karyotype and FISH analysis revealed that, of the four cases showing Y chromosome microdeletion, three cases had a 47,XXY/46,XY chromosomal pattern and one case had a 46,XY/47,XXY/48,XXXY/48,XXYY chromosomal pattern. The testicular FNAC of one sample with Y chromosome microdeletion revealed Sertoli cell-only type of morphology. However, no Y chromosome microdeletions were observed in any of the 13 fertile men. All patients with KFS had elevated plasma FSH levels. Conclusion： Patients with KFS may harbor Y chromosome microdeletions and screening for these should be a part of their diagnostic work-up, particularly in those considering assisted reproductive techniques. （Asian JAndrol 2006 Jan; 8： 81-88）

关键词： azoospermia azoospermia factor follicle stimulating hormone Klinefelter's syndrome Y chromosome microdeletion

Systematic review with expert consensus on use of extracorporeal hemoadsorption in septic shock:An Indian perspective

在线全文

学校读者我要写书评

暂无评论

World Journal of Critical Care Medicine 2024年第1期13卷 65-75页

作者： Yatin Mehta Abdul Samad Ansari Amit kumar Mandal Dipanjan Chatterjee Gauri Shankar Sharma Prachee Sathe Purvesh V Umraniya Rajib Paul Sachin gupta Vinod Singh Yogendra Pal Singh Institute of Critical Care and Anesthesiology Medanta The MedicityGurgaon 122001HaryanaIndia Department of Critical Care Nanavati Max Super Specialty HospitalMumbai 400065India Department of Pulmonology Sleep and Critical CareFortis HospitalMohaliPunjabMohali 160062PunjabIndia Department of Cardio-Puimonary Critical Care Medica Superspecialty HospitalKolkata 700099India Department of Critical Care Medicine Fortis HospitalNew Delhi 110070India Department of Critical Care Medicine D.Y.Patil Medical CollegeSant Tukaram NagarPimpri ColonyPimpri-ChinchwadPune 411018India Department of Critical Care Medicine Bhailal Amin General HospitalVadodara 390003GujaratIndia Department of Internal Medicine Apollo HospitalsJubilee HillsHyderabad 500033India Department of Anaesthesiology Narayana Superspeciality HospitalGurugram 122002India Department of Critical Care Medicine Institute of Critical Care MedicineHospital Name-Sir Ganga Ram HospitalNew Delhi 110001India Department of Critical Care Medicine Max Super Speciality HospitalDelhi 110092India

BACKGROUND Septic shock is a severe form of sepsis characterised by deterioration in circulatory and cellular-metabolic *** standard therapy,the outcomes are *** adjuvant therapy,such as CytoSorb®extracorporeal haemoadsorption device,has been investigated and shown promising ***,there is a lack of some guidance to make clinical decisions on the use of CytoSorb®haemoadsorption as an adjuvant therapy in septic shock in Indian ***,this expert consensus was *** To formulate/establish specific consensus statements on the use of CytoSorb®haemoadsorption treatment based on the best available evidence and contextualised to the Indian *** We performed a comprehensive literature on CytoSorb®haemoadsorption in sepsis,septic shock in PubMed selecting papers published between January 2011 and March 20232021 in English *** statements for a consensus document were developed based on the summarised literature analysis and identification of knowledge *** a modified Delphi approach combining evidence appraisal and expert opinion,the following topics related to CytoSorb®in septic shock were addressed:need for adjuvant therapy,initiation timeline,need for Interleukin-6 levels,duration of therapy,change of adsorbers,safety,prerequisite condition,efficacy endpoints and management *** expert members from critical care,emergency medicine,and the intensive care participated and voted on nine statements and one open-ended *** Eleven expert members from critical care,emergency medicine,and the intensive care participated and voted on nine statements and one open-ended *** 11 experts in the consensus group(100%)participated in the first,second and third round of *** three iterative voting rounds and adapting two statements,consensus was achieved on nine statements out of nine *** consensus expert panel also recognised the necessity to form an associatio

关键词： Consensus CytoSorb Cytokine Hemoadsorption Refractory Sepsis Septic shock

Pharmacological, Ethnomedicinal, and Evidence-Based Comparative Review of Moringa oleifera Lam.(Shigru) and Its Potential Role in the Management of Malnutrition in Tribal Regions of India, Especially Chhattisgarh

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Traditional Chinese Medicine 2022年第3期8卷 314-338页

作者： Kishor Sonewane Sharda Swaroop Chouhan Mariappan Rajan Nagendra Singh Chauhan Om Prakash Rout Awanish kumar Gyanendra Singh Baghel Prashant kumar gupta Department of Kaumarabhritya-Balaroga Shri NPA Government Ayurveda CollegeRaipurChhattisgarhIndia Department of Natural Chemistry Madurai Kamraj UniversityMaduraiTamil NaduIndia Drug Testing Lab Avam Anushandhan Kendra Department of AYUSHChhattisgarhIndia Department of Dravya Guna Shri NPA Government Ayurveda CollegeRaipurChhattisgarhIndia Department of Biotechnology National Institute of TechnologyRaipurChhattisgarhIndia

Moringa oleifera Lam.(Shigru)(Moringaceae family) is a traditional medicine used for control of diabetes, obesity, asthma, and cardiac,liver, gastrointestinal, infective, and brain disorders, such as depression and Alzheimer's disease. In Ayurvedic literature, Shigru is among few drugs having Balya(nourishing) as well as Medohara(antiobesity) property. This review focuses on valid connections between the properties documented in ancient literature and current pharmacological knowledge of Moringa, including pharmacological actions, phytochemistry,botanical description, and how Moringa can tackle malnutrition in India, especially Chhattisgarh. All information about M. oleifera was obtained from electronic scientific databases such as PubMed, Web of Science, Scopus, ScienceDirect, Elsevier, Google Scholar, Traditional Knowledge Digital Library, and Indian Traditional Books(Ancient Ayurveda literatures, The Wealth of India, and The Ayurvedic Formulary of India), postgraduate/doctoral thesis, and googling the keyword M. oleifera. M. oleifera have anti-oxidant, antimicrobial, anti-diabetic,anti-obesity, anti-inflammatory, cardioprotective, hepatoprotective, neuroprotective, gastroprotective, wound-healing properties and it can potentially tackle malnutrition. This review describes the key information related to botanical description of M. oleifera, phytochemistry,pharmacological actions, clinical studies, toxicological studies, better utilization as food therapeutics, and ethnobotanical and evidence-based comparative review of M. oleifera. M. oleifera can effectively tackle malnutrition in India, especially Chhattisgarh. The authors emphasize the need for future in-depth ethnopharmacological lead-based research and clinical studies to expand M. oleifera pharmacological activities,clinical efficacy, and safety.

关键词： Ethnobotanical practices ethnomedicine Moringa oleifera phytochemicals pharmacological action

Adder design using a 5-input majority gate in a novel “multilayer gate design paradigm” for quantum dot cellular automata circuits

在线全文

学校读者我要写书评

暂无评论

Journal of Semiconductors 2015年第4期36卷 95-103页

作者： Rohit kumar Bahniman Ghosh Shoubhik gupta Department of Electrical Engineering Indian Institute of Technology Kanpur Microelectronics Research Center 10100Burnet RoadBldg. 160University of Texas at Austin University of Glasgow

This paper proposes a novel design paradigm for circuits designed in quantum dot cellular automata （QCA） technology. Previously reported QCA circuits in the literature have generally been designed in a single layer which is the main logical block in which the inverter and majority gate are on the base layer, except for the parts where multilayer wire crossing was used. In this paper the concept of multilayer wire crossing has been extended to design logic gates in multilayers. Using a 5-input majority gate in a multilayer, a 1-bit and 2-bit adder have been designed in the proposed multilayer gate design paradigm. A comparison has been made with some adders reported previously in the literature and it has been shown that circuits designed in the proposed design paradigm are much more efficient in terms of area, the requirement of QCA cells in the design and the input-output delay of the circuit. Over all, the availability of one additional spatial dimension makes the design process much more flexible and there is scope for the customizability of logic gate designs to make the circuit compact.

关键词： multilayer gate design QCA adders MUX 5-input majority voter

Role of subjective visual vertical in patients with posterior canal benign paroxysmal positional vertigo as a prognostic marker after canalith repositioning maneuver

在线全文

学校读者我要写书评

暂无评论

Journal of Otology 2022年第3期17卷 111-115页

作者： Sanjeev Saxena Bhaumik Patel Ravi Roy Himanshu Swami Sanajit kumar Singh Sunil Goyal Rajeev Chugh Devendra kumar gupta Sween Banger Mahesh Ravanikutty Sneha Yadav Department of ENT World College of Medical Science and ResearchJhajjarHaryanaIndia Department of ENT-HNS Army Hospital Research and ReferralNew DelhiIndia

Objective:To study the potential role of subjective visual vertical(SVV)as a prognostic marker for canalith repositioning maneuver(CRM)in patients with posterior canal benign paroxysmal positional vertigo(PC-BPPV)for the Indian ***:SVV was examined in 30 patients with PC-BPPV before and after canalith repositioning maneuver and after complete resolution of *** parameters included the mean of 10 angular tilt readings and direction of deviation,which were compared before and after CRM and following complete resolution of ***:The angle of SVV tilt was greater and deviated towards the affected ear before CRM in all patients,which decreased significantly shortly after CRM and continued to decrease after complete resolution of PC-BPPV(p<0.0001).Conclusions:SVV can be used to test utricular dysfunction in *** angle of tilt improves in response to CRM,which may be used as a prognostic marker in patients with PC-BPPV receiving CRM.

关键词： Benign paroxysmal positional vertigo(BPPV) Subjective visual vertical(SVV) Otoliths(canaliths) Canalith repositioning maneuver(CRM)

Effects of particle size and confining pressure on breakage factor of rockfill materials using medium triaxial test

在线全文

学校读者我要写书评

暂无评论

Journal of Rock Mechanics and Geotechnical Engineering 2016年第3期8卷 378-388页

作者： Ashok kumar gupta Civil Engineering Department Jaypee University of Information Technology

Rockfill dams are mostly constructed using blasted rockfill materials obtained by blasting rocks or alluvial rockfill materials collected from the riverbeds. Behaviors of rockfill materials and their characterization signifcantly depend on breakage factor observed during triaxial loading. In this paper, two modeled rockfill materials are investigated by using medium triaxial cell. Drained triaxial tests are conducted on various sizes of modeled rockfill materials used in the two dams, and test data are analyzed accordingly. Breakage factor of rockfill material is studied and the effects of particle size and confining pressure on breakage factor are investigated using medium triaxial cell as many researchers have already conducted investigation using large triaxial cell.

关键词： Triaxial testsRockfill materialsParticle sizeConfining pressureBreakage factor

The Trends in Maternal Mortality between 1996 and 2009 in Guizhou, China: Ethnic Differences and Associated Factors

在线全文

学校读者我要写书评

暂无评论

Journal of Huazhong University of Science and Technology(Medical Sciences) 2015年第1期35卷 140-146页

作者：杜清练武 ?yvind Nss Espen Bjertness Bernadette nirmal kumar 石淑华 School of Public Health and Management of Binzhou Medical University The Norweigian Institute of Public Health The Faculty of Medicine University of Oslo Tibet University Medical College Norweigian Center for Minority Health Research Tongji Medical College Huazhong University of Science and Technology

China bears a large burden of global maternal mortality, and the largest burden of maternal deaths in China is in poor western provinces. This study aimed to investigate the trends in maternal mortality and its associated factors in Guizhou province of western China between 1996 and 2009, and examine differences between minority and non-minority counties. A population-based, longitudinal, retrospective study was performed in a poor western province of China with a considerably large ethnic minority population. All 86 counties/districts of Guizhou were included with population at county, township and village level. Maternal mortality data were collected from routine reporting database of Guizhou Provincial Health Bureau. Trend and comparative analyses and multivariate linear regression analyses were performed using SPSS 17.0. Maternal mortality ratio（MMR） and its change over time, differences between ethnic groups were analyzed. A declining trend in maternal mortality and rising trend in hospital delivery in Guizhou was observed; ethnic differences between two ethnic groups persisted. The reduction in maternal mortality between 1996 and 2009 was related with increased gross domestic product, decreased male illiteracy rate, and increased hospital delivery rate. We found the declining trends in maternal mortality in Guizhou with persisting ethnic differences. The declining trends are related with economic development, hospital delivery and male illiteracy. Effective health education on maternal health is urgently needed for the minority groups, and basic education for the new generation should be enhanced to eradicate the illiteracy.

关键词： maternal mortality trends ethnic differences China