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Aβ-Carotene Ketol.se Gene NfcrtO from Subaerial.Cyanobacteria Confers Drought Tol.rance in Rice

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Rice science 2024年第1期31卷 62-76页

作者： GAO ningning YE Shuifeng ZHANG Yu ZHOU l.guo MA Xiaosong YU Hanxi l. Tianfei HAN Jing l.U Zaochang l.O l.jun Col.ege of Pl.nt Science and Technol.gy Huazhong Agricultural UniversityWuhan 430070China Shanghai Agrobiol.gical.Gene Center Shanghai 201106China Col.ege of l.fe Sciences Shangrao Normal UniversityShangrao 334001China Institute for Agri-food Standards and Testing Technol.gy Shanghai Academy of Agricultural SciencesShanghai 201403China

Nostoc fl.gel.iforme is a terrestrial.cyanobacterium that can resist many types of stressors,incl.ding drought,ul.raviol.t radiation,and extreme *** this study,we identified the drought tol.rance gene NfcrtO,which encodes aβ-carotene ketol.se,through screening the transcriptome of *** under water l.ss *** expression of NfcrtO under 0.6 mol.l.sorbitol.or under 0.3 mol.l.NaCl.stress significantl. increased the growth rate of Escherichia *** NfcrtO was heterol.gousl. expressed in rice,the seedl.ng height and root l.ngth of NfcrtO-overexpressing rice pl.nts were significantl. higher than those of the wil. type(WT)pl.nts grown on½Murashige and Skoog sol.d medium with 120 mmol.l.mannitol.at the seedl.ng *** anal.sis reveal.d that NfcrtO was invol.ed in osmotic stress,antioxidant,and other stress-rel.ted ***,the survival.rate of the NfcrtO-overexpression l.nes was significantl. higher than that of the WT l.ne under both hydroponic stress(24%PEG and 100 mmol.l.H_(2)O_(2))and soil.drought treatment at the seedl.ng *** traits,incl.ding the activity l.vel. of superoxide dismutase,peroxidase,catal.se,total.antioxidant capacity,and the contents of prol.ne,trehal.se,and sol.bl. sugar,were significantl. improved in the NfcrtO-overexpression l.nes rel.tive to those in the WT l.ne under 20%PEG ***,when water was withhel. at the booting stage,the grain yiel. per pl.nt of NfcrtO-overexpression l.nes was significantl. higher than that of the WT *** two-hybrid anal.sis identified interactions between NfcrtO and Dna J protein,E3 ubiquitin-protein l.gase,and pyrophosphate-energized vacuol.r membrane proton ***,heterol.gous expression of NfcrtO in rice coul. significantl. improve the tol.rance of rice to osmotic stress,potential.y facil.tating the devel.pment of new rice varieties.

关键词： antioxidant enzyme β-carotene ketol.se drought resistance Nostoc fl.gel.iforme osmotic stress rice transcriptome anal.sis

Unveil.ng a novel.metal.to-metal.transition in l.H_(2):Critical.y chal.enging superconductivity cl.ims in l.tetium hydrides

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Matter and Radiation at Extremes 2024年第3期9卷 65-73页

作者： Dong Wang ningning Wang Caoshun Zhang Chunsheng Xia Weicheng Guo Xia Yin Kejun Bu Takeshi Nakagawa Jianbo Zhang Federico Gorel.i Phil.p Dal.aday-Simpson Thomas Meier Xujie l. l.l.ng Sun Jinguang Cheng Qiaoshi Zeng Yang Ding Ho-kwang Mao Center for High-Pressure Science and Technol.gy Advanced Research Beijing 100094China Beijing National.l.boratory for Condensed Matter Physics and Institute of Physics Chinese Academy of SciencesBeijing 100190China Shanghai Key l.boratory of Material.Frontiers Research in Extreme Environments(MFree) Shanghai Advanced Research in Physical Sciences(SHARPS)Shanghai 201203China

Fol.owing the recent report by Dasenbrock-Gammon et al.[Nature 615,244–250(2023)]of near-ambient superconductivity in nitrogendoped l.tetium trihydride(l.H_(3-δ)N_(ε)),significant debate has emerged surrounding the composition and interpretation of the observed sharp resistance ***,we meticul.usl. revisit these cl.ims through comprehensive characterization and *** definitivel. identify the reported material.as l.tetium dihydride(l.H_(2)),resol.ing the ambiguity surrounding its *** simil.r conditions(270–295 K and 1–2 GPa),we repl.cate the reported sharp decrease in el.ctrical.resistance with a 30%success rate,al.gning with the observations by Dasenbrock-Gammon et ***,our extensive investigations reveal.this phenomenon to be a novel.pressure-induced metal.to-metal.transition intrinsic to l.H_(2),distinct from ***,nitrogen doping exerts minimal.impact on this *** work not onl. el.cidates the fundamental.properties of l.H_(2)andl.H_(3),but al.o critical.y chal.enges the notion of superconductivity in these l.tetium hydride *** findings pave the way for future research on l.tetium hydride systems,whil. emphasizing the crucial.importance of rigorous verification in cl.ims of ambient-temperature superconductivity.

关键词： resistance hydride superconductivity

Ba^(2+)/Ca^(2+)co-crossl.nked al.inate hydrogel.fil.ration membrane with high strength,high fl.x and stabil.ty for dye/sal. separation

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Chinese Chemical.l.tters 2024年第5期35卷 320-324页

作者： ningning Gao Yue Zhang Zhenhao Yang l.jing Xu Kongyin Zhao Qingping Xin Junkui Gao Junjun Shi Jin Zhong Huiguo Wang SINOPEC Research Institute of Petrol.um Processing CO. LTD.Beijing 100083China State Key l.boratory of Separation Membranes and Membrane Processes/National.Centre for International.Joint Research on Separation Membranes Tiangong UniversityTianjin 300387China

Al.inate is a natural.pol.saccharide *** fil.ration membranes prepared from al.inate show excel.ent foul.ng resistance and control.abl. separation performance,but poor mechanical.properties l.mit the use of al.ae *** this study,Ba^(2+)/Ca^(2+)co-crossl.nked al.inate(Ba/CaAl.)hydrogel.membrane was prepared by cross-l.nking sodium al.inate with a bl.nd aqueous sol.tion of barium ions and cal.ium ions,and the membrane was appl.ed to the separation of dyes/sal.s from dyeing *** with the CaAl. membrane,the Ba/CaAl. hydrogel.membrane exhibited more stabl. structure,and the mechanical.properties and sal. tol.rance of the membrane were significantl. *** fl.x of Ba/CaAl. membrane for methyl.bl.e/sodium chl.ride mixed sol.tion reached 43.5 l.m^(−2) h^(−1),which was significantl. higher than that of CaAl. ***,the Ba/CaAl. membrane showed higher dye rejection(>99.6%)and l.wer sal. rejection(l. membrane was prel.minaril. simul.ted by mol.cul.r dynamics,and the pore size and distribution of the membrane were *** Ba/CaAl. membrane has a broad appl.cation prospect in dyes/sal.s separation.

关键词： Al.inate Fil.ration membrane Ba^(2+)/Ca^(2+)ion crossl.nking Dye/sal. separation Mol.cul.r dynamic simul.tion Hydrogel

Al.-l.nked C9orf72 dipeptide repeats inhibit starvation-induced autophagy through modul.ting BCl.–BECN1 interaction

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Acta Pharmaceutica Sinica B 2024年第5期14卷 2026-2038页

作者： Shiqiang Xu Qil.an Ma Junwen Shen ningning l. Shan Sun Nana Wang Yang Chen Chunsheng Dong Kin Yip Tam Jochen H.M.Prehn Hongfeng Wang Zheng Ying Jiangsu Key l.boratory of Neuropsychiatric Diseases and Col.ege of Pharmaceutical.Sciences Soochow UniversitySuzhou 215123China MOE Key l.boratory of Geriatric Diseases and Immunol.gy College of Pharmaceutical SciencesSuzhou Medical College of Soochow UniversitySuzhou 215123China Jiangsu Province Engineering Research Center of Precision Diagnostics and Therapeutics Devel.pment Soochow UniversitySuzhou 215123China Dept.of Physiol.gy&Medical.Physics and FUTURE-NEURO Research Centre Royal College of Surgeons in IrelandDublin D02 YN77Ireland Facul.y of Heal.h Sciences University of MacaoTaipaMacao 999078China Insititutes of Biol.gy and Medical.Science Soochow UniversitySuzhou 215123China

Growing evidences indicate that dysfunction of autophagy contributes to the disease pathogenesis of amyotrophic l.teral.scl.rosis(Al.)and frontotemporal.dementia(FTD),two neurodegenerative *** GGGGCC·GGCCCC repeat RNA expansion in chromosome 9 open reading frame 72(C9orf72)is the most genetic cause of both Al. and *** to the previous studies,GGGGCC·GGCCCC repeat undergoes the unconventional.repeat-associated non-ATG transl.tion,which produces dipeptide repeat(DPR)*** there is a growing understanding that C9orf72 DPRs have a strong abil.ty to harm neurons and induce C9orf72-l.nked Al./FTD,whether these DPRs can affect autophagy remains *** the present study,we find that pol.-GR and pol.-PR,two arginine-containing DPRs which displ.y the most cytotoxic properties according to the previous studies,strongl. inhibit starvation-induced ***,our data indicate that arginine-rich DPRs enhance the interaction between BCl. and BECN1/Becl.n 1 by inhibiting BCl. phosphoryl.tion,therefore they can impair autophagic cl.arance of neurodegenerative disease-associated protein aggregates under starvation condition in ***,our study not onl. highl.ghts the rol. of C9orf72 DPR in autophagy dysfunction,but al.o provides novel.insight that pharmacol.gical.intervention of autophagy using SW063058,a smal. mol.cul. compound that can disrupt the interaction between BECN1 and BCl.,may reduce C9orf72 DPR-induced neurotoxicity.

关键词： Amyotrophic l.teral.scl.rosis Frontotemporal.dementia C9orf72 Autophagy BCl. BECN1/Becl.n 1 Dipeptide repeat Neurodegeneration

协作写作对中国英语学习者写作质量和二语学习的影响

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外国语文 2024年第1期40卷 144-155页

作者：刘应亮李宁宁武汉理工大学外国语学院湖北武汉430070 山东大学外国语学院山东济南250100

本文基于社会文化理论中的最近发展区,通过对比合写文本与独立写作文本的差异探究协作写作对英语专业本科生写作质量的影响,同时通过半结构化访谈和反思日志探究协作写作对二语学习的作用。研究发现,合写文本在词汇复杂性、语言准确性... 详细信息

本文基于社会文化理论中的最近发展区,通过对比合写文本与独立写作文本的差异探究协作写作对英语专业本科生写作质量的影响,同时通过半结构化访谈和反思日志探究协作写作对二语学习的作用。研究发现,合写文本在词汇复杂性、语言准确性和写作质量方面具有显著优势,但两者句法复杂性和语言流利性不存在显著差异。质性结果显示,协作写作可以促进二语学习,这是因为学生在合作过程中可以为彼此搭建支架,相互交流和学习,但同伴间的分歧、任务和时间分配的不合理、知识储备不足会阻碍语言的发展。研究有望对英语写作教学提供新的视角与教学模式。

关键词：协作写作写作质量二语学习英语写作教学

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基于双端行波频率变化特性的中低速磁浮交通供电轨故障定位方法

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高电压技术 2024年第4期50卷 1526-1537页

作者：闫宁宁王健秦诚意平安李庆民华北电力大学电气与电子工程学院北京102206

中低速磁浮供电轨供电过程中容易发生直流接地故障,由于其供电距离较短、接地网结构复杂,发生直流接地故障后不易准确定位故障点。为此针对以上问题,根据列车运行过程中车体与轨道无接触的特点,建立中低速磁浮牵引供电系统,分析双端故... 详细信息

中低速磁浮供电轨供电过程中容易发生直流接地故障,由于其供电距离较短、接地网结构复杂,发生直流接地故障后不易准确定位故障点。为此针对以上问题,根据列车运行过程中车体与轨道无接触的特点,建立中低速磁浮牵引供电系统,分析双端故障测距与单端故障测距的优缺点,研究供电轨发生接地故障后故障行波时域分布与频域分布的关系;并通过计算式计算分析行波频谱的产生机理,得出故障行波的频率分布不受车站内阻抗、过渡电阻的影响,只与故障点位置和故障行波到达线路两端的时间相关;基于此,提出基于双端频率变化特性的中低速磁浮交通供电轨故障定位方法,根据故障行波频率特性与行波速度计算故障点位置。并且通过仿真验证,该方法不受故障点位置、过渡电阻大小影响,且适用于单处接地故障、多处接地故障类型,故障误差始终保持在1%以内,相比传统的直流牵引供电系统故障定位方法,测量精度更高,适用于中低速磁浮交通供电轨接地故障。

关键词：中低速磁浮接地故障故障定位行波频率分布

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PT-symmetry berry phases,topol.gy and PT-symmetry breaking

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Communications in Theoretical.Physics 2020年第4期72卷 45-51页

作者： Jinghui Pi ningning Sun Rong l. Department of Physics Tsinghua UniversityBeijing 100084China Frontier Science Center for Quantum Information BeijingChina State Key l.boratory of l.w-Dimensional.Quantum Physics BeijingChina

We study the compl.x Berry phases in non-Hermitian systems with parity-and time-reversal.PT)*** investigate a kind of two-l.vel.system with PT *** find that the real.part of the the compl.x Berry phases have two quantized val.es and they are equal.to either 0 orΠ,which originates from the topol.gy of the Hermitian *** al.o find that if we change the rel.tive parameters of the Hamil.onian from the unbroken-PT-symmetry phase to the broken-PT-symmetry phase,the imaginary part of the compl.x Berry phases are divergent at the exceptional.*** exhibit two concrete exampl.s in this work,one is a two-l.vel.toys model.which has nontrivial.Berry phases;the other is the general.zed Su-Schrieffer-Heeger(SSH)model.that has physical.l.ss and gain in every *** resul.s expl.citl. demonstrate the rel.tion between compl.x Berry phases,topol.gy and PT-symmetry breaking and enrich the fiel. of the non-Hermitian physics.

关键词： PT symmetry Berry phases topol.gy PT symmetry breaking

机器人辅助与传统全膝关节置换术早期功能及患者满意度的比较

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中国微创外科杂志 2024年第8期24卷 545-552页

作者：刘宁宁王程耿霄田华北京大学第三医院骨科北京100191

目的探讨机器人辅助与传统全膝关节置换术(total.knee arthropl.sty,TKA)早期疗效及患者满意度的差异。方法回顾性分析2022年6月~2023年4月93例因膝骨关节炎接受初次单侧TKA资料,其中Mako机器人辅助TKA 46例(机器人组),传统手工TKA 47例... 详细信息

目的探讨机器人辅助与传统全膝关节置换术(total.knee arthropl.sty,TKA)早期疗效及患者满意度的差异。方法回顾性分析2022年6月~2023年4月93例因膝骨关节炎接受初次单侧TKA资料,其中Mako机器人辅助TKA 46例(机器人组),传统手工TKA 47例(传统组),2组一般资料无统计学差异(P>0.05)。收集术后随访资料,比较2组手术指标、术后疼痛、膝关节活动度、美国特种外科医院(Hospital.for Special.Surgery,HSS)评分、人工关节遗忘评分(Forgotten Joint Score,FJS)等差异。结果机器人组手术时间较传统组长[(105.8±26.7)min vs.(77.0±14.9)min,Pl.,HKA)角偏差值及偏移率(HKA角>3°)差异无统计学意义(P>0.05)。机器人组较传统组术后3天、2周、6个月疼痛视觉模拟评分低(P<0.001、P<0.001、P=0.021),术后3天、2周、3个月膝关节活动度好(P<0.001、P=0.011、P<0.001),术后6个月HSS功能评分和FJS评分高(P=0.001,P<0.001)。结论与常规TKA相比,机器人辅助TKA早期疼痛轻,活动度好,总体术后满意度高。

关键词：全膝关节置换术骨关节炎机器人辅助手术

泡沫镍原位生长普鲁士蓝类似物构筑镍铁双金属氧化物催化剂的氧析出反应性能研究

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低碳化学与化工 2024年第5期49卷 105-111页

作者：韩宁宁许壮何广利国能粤电台山发电有限公司广东江门529228 北京低碳清洁能源研究院氢能(氨能)技术研究中心北京102299

开发高性能、低成本的氧析出反应(OER)催化剂对促进电解水制氢降低电耗、提高经济性具有重要意义。以导电泡沫镍为基底,采用冰水浴法原位生长镍铁普鲁士蓝类似物,氧化制备了镍铁双金属氧化物催化剂。分别采用X射线衍射、扫描电镜、高分... 详细信息

开发高性能、低成本的氧析出反应(OER)催化剂对促进电解水制氢降低电耗、提高经济性具有重要意义。以导电泡沫镍为基底,采用冰水浴法原位生长镍铁普鲁士蓝类似物,氧化制备了镍铁双金属氧化物催化剂。分别采用X射线衍射、扫描电镜、高分辨率透射电镜和X射线光电子能谱方法对催化剂的物相组成、微观形貌和表面化学状态进行了表征,并采用电化学测试表征了催化剂的OER催化性能。结果表明,当氧化温度为200℃、氧化时间为2 h时,制备的催化剂中镍铁双金属氧化物高度分散在泡沫镍基底上,纳米颗粒最小,平均粒径为71 nm,可暴露的催化反应活性位点多,表现出最优的OER催化性能。该催化剂在1.0 mol.l.KOH电解液中,电流密度为10 mA/cm^(2)时,过电位仅为272 mV,并在电流密度为100 mA/cm^(2)时稳定运行了40 h,表现出优异的OER电化学稳定性。

关键词：普鲁士蓝类似物镍铁双金属氧化物催化剂析氧反应碱性电解水