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Dual-Peak Bragg Gratings Inscribed in an All-Solid Photonic Bandgap Fiber for Sensing Applications

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Chinese Physics Letters 2012年第7期29卷 110-113页

作者： ZHANG Ji-Huang LIU ning-liang WANG Ying JI Ling-Ling LU Pei-Xiang Wuhan National Laboratory for Optoelectronics Huazhong University of Science and TechnologyWuhan 430074 Laboratory of Optical Information Technology Wuhan Institute of TechnologyWuhan 430073 College of Sciences Wuhan University of Science and TechnologyWuhan 430081

Bragg gratings are inscribed in an all-solid photonic bandgap fiber by use of femtosecond laser *** structure is observed in the transmission spectrum of the induced grating,which is formed by the coupling between the forward-propagating fundamental core mode and the backward-propagating core mode or *** characteristics of the device are investigated experimentally by employing strain and temperature tests,and similar behavior is obtained for both resonant *** strain and temperature sensitivities are 0.968pm/με and 12.01pm/℃,and 0.954pm/pε and 12.04pm/℃,for the two peaks,*** device would find potential applications in real optical fiber sensing without extra reference gratings.

关键词： fiber Dual backward

Enhanced tensile properties and wear resistance of additively manufactured CoCrFeMnNi high-entropy alloy at cryogenic temperature

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Rare Metals 2022年第4期41卷 1210-1216页

作者： Hong-Ge Li Peng-Cheng Che Xiao-Kun Yang Yong-Jiang Huang Zhi-liang ning Jian-Fei Sun Hong-Bo Fan School of Materials Science and Engineering Harbin Institute of TechnologyHarbin 150001China Harbin-Electric Power Generation Equipment National Engineering Research Center Co. LtdHarbin 150028China

Here,bulk CoCrFeMnNi high-entropy alloy was prepared via laser melting deposition,and its microstructure and mechanical properties at room and cryogenic temperature were investigated by a series of microstructural character-izations and mechanical *** results showed that the as-built samples possessed a single fcc phase and highly dense *** to the mechanical prop-erties at room temperature,tensile properties,microhard-ness and wear resistance of the as-built samples showed a signiflcant enhancement at cryogenic temperature,which was attributed to the deformation mechanism converting from dislocation slipping to deformation twinning at cryogenic *** formation of deformation nanotwins signiflcantly improved the deformation resis-tance in cryogenic conditions,and the sliding wear in the liquid nitrogen could decrease the oxygen concentration,suppress the generation of oxide particles and thus enhance the wear resistance.

关键词： wear cryogenic alloy

Practical Application and Development Trend of External Treatment of Zhuang Medicine Based on CiteSpace

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Agricultural Biotechnology 2023年第4期12卷 65-70页

作者： Binglin HU ning liang Guangxi University of Chinese Medicine Nanning 530001China

The external treatment of Zhuang medicine is a treatment method commonly used from outside the human *** advantages of external treatment methods are easy operation and small side *** are more familiar with medicated thread moxibustion,meridian tendon massage,and acupuncture therapy of Zhuang *** the curative effect of external treatment is significant,it is little known due to insufficient publicity and other *** purpose of this project was to comprehensively analyze and organize the latest relevant scientific and technological literature graphs in the study on clinical external treatment of Zhuang medicine using CiteSpace software and adopting the research method of visual literature graph *** research status and research development process of the external treatment of Zhuang medicine in Chinese literature were summarized,which has been able to present the current trends and future research prospects of the development and research of external treatment of Zhuang medicine in China in detail and ***,307 papers were selected and *** Yingcai and Pang Yuzhou were the authors with the largest number of documents and had formed a stable core research *** analysis showed that Guangxi University of Chinese Medicine published the largest number of research documents,and there was less cooperation between *** present,the research on the external treatment methods of Zhuang medicine is still in the development stage,which provides ideas and reference for quickly mastering the research hotspot of the external treatment method.

关键词： External treatment of Zhuang medicine Visual analysis CiteSpace Knowledge map

Increased mitochondrial fission drives the reprogramming of fatty acid metabolism in hepatocellular carcinoma cells through suppression of Sirtuin 1

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Cancer Communications 2022年第1期42卷 37-55页

作者： Dan Wu Yi Yang Yiran Hou Zifeng Zhao ning liang Peng Yuan Tao Yang Jinliang Xing Jibin Li Department of Physiology and Pathophysiology State Key Laboratory of Cancer BiologyFourth Military Medical UniversityXi’anShaanxi 710032P.R.China Department of Pain Treatment Tangdu HospitalFourth Military Medical UniversityXi’anShaanxi 710032P.R.China Department of General Surgery Tangdu HospitalFourth Military Medical UniversityXi’anShaanxi 710038P.R.China Experimental Teaching Center of Basic Medicine Fourth Military Medical UniversityXi’anShaanxi 710038P.R.China

Background:Mitochondria are dynamic organelles that constantly change their morphology through fission and fusion ***,abnormally increased mitochondrial fission has been observed in several types of ***,the functional roles of increased mitochondrial fission in lipid metabolism reprogramming in cancer cells remain *** study aimed to explore the role of increased mitochondrial fission in lipid metabolism in hepa-tocellular carcinoma(HCC)***:Lipid metabolism was determined by evaluating the changes in the expressions of core lipid metabolic enzymes and intracellular lipid *** rate of fatty acid oxidation was evaluated by[PH]-labelled oleic *** mito-chondrial morphology in HCC cells was evaluated by fluorescent *** expression of protein was determined by real-time PCR,imnmunohistochemistry and Western ***:Activation of mitochondrial fission significantly promoted de novo fatty acid synthesis in HCC cells through upregulating the expression of lipogenic genes fatty acid synthase(FASN),acetyl-CoA carboxylasel(ACCI),and elonga-tion of very long chain fatty acid protein 6(ELOVL6),while suppressed fatty acid oxidation by downregulating carnitine palmitoyl transferase 1A(CPTIA)and acyl-CoA oxidase 1(ACOX1).Consistently,suppressed mitochondrial fission exhibited the opposite ***,in vitro and in vivo studies revealed that mitochondrial fission-induced lipid metabolism reprogramming significantly promoted the proliferation and metastasis of HCC ***,mito-chondrial fission increased the acetylation level of sterol regulatory element-binding protein 1(SREBPI)and peroxisome proliferator-activated receptor coaC-tivator 1 alpha(PGC-1a)by suppressing nicotinamide adenine dinucleotide(NAD+)/Sirtuin 1(SIRTI)*** elevated SREBP1 then upregulated the expression of FASN,ACC1 and ELOVL6 in HCC cells,while PGC-1c/PPARa sup-pressed the expression of CPTIA and ACOXL Conclusi

关键词： hepatocellular carcinoma lipogenesis fatty acid oxidation metabolic reprogramming mito-chondrial fission Sirtuin 1

Components of complex interventions for healthcare: A narrative synthesis of qualitative studies

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Journal of Traditional Chinese Medical Sciences 2020年第2期7卷 181-188页

作者： Sisi Ma He Yu ning liang Sijia Zhu Xun Li Nicola Robinson Jianping Liu Centre for Evidence-Based Chinese Medicine Beijing University of Chinese MedicineBeijing100029China School of Traditional Chinese Medicine Beijing University of Chinese MedicineBeijing102488China Institute of Basic Research in Clinical Medicine China Academy of Chinese Medical SciencesBeijing100700China School of Health and Social Care London South Bank UniversityLondonSE10AAUnited Kingdom

Objective:Qualitative research on therapeutic components is necessary to evaluate the efficacy of complex interventions in *** few qualitative syntheses have been conducted,this study aimed to derive a new conceptual framework for understanding the components of complex interventions and provide evidence for the implementation and evaluation of complex healthcare ***:A systematic search of seven databases was conducted to identify qualitative studies that explored components of complex healthcare ***-ethnography was used to analyze the data and thematic analysis was used to build the conceptual ***:Of the 35 included studies,most complex interventions were non-pharmacological,with cancer accounting for 22%,mental health for 14%,and stroke for 8%.Half of the studies were conducted in the United *** main categories emerged:what should healthcare workers do?what qualifications should they have?and what should patients do?Five main themes were identified:psychological,biological,cognitive and behavioral,environmental,and social ***:This analysis provides a reference for designing components of complex interventions in further studies.

关键词： Therapeutic component Psychological support Social support Cognitive and behavioral support Complex interventions

Crystal structures and magnetic performance of nanocrystalline Sm-Co compounds

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Frontiers of Materials Science 2012年第3期6卷 207-215页

作者： Xiao-Yan SONG Zhe-Xu ZHANG Nian-Duan LU Hai-ning liang Ding-Peng LI Xiang-Quan YAN Jiu-Xing ZHANG College of Materials Science and Engineering Key Laboratory of Advanced Functional Materials(Ministry of Education)Beijing University of TechnologyBeijing 100124China

A variety of intermetallic compounds in the binary Sm Co system were reviewed, and the contents were focused on the crystal structures, magnetic properties and the nanoscale effects. The representative nanocrystalline Sm-Co compounds were introduced in details, the diagrams for their lattice structures and the atomic sites and occupancies were provided. Moreover, the magnetic properties of the nanocrystalline Sm-Co compounds were compared with those of the conventional polycrystalline counterparts. It showed that the nanocrystalline Sm Co compounds exhibit special phase stability and remarkably enhanced magnetic performance, which are promising candidates for the matrix phases to develop permanent magnets, particularly the advanced high-temperature magnetic materials.

关键词： Sm-Co compounds nanoscale crystal structure magnetic performance

Microstructures and mechanical properties of laser-directed energy deposited CrCoNi medium-entropy alloy

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Rare Metals 2024年第7期43卷 3286-3300页

作者： Wen-Jie Zhao Chang-Yu Liu Peng-Cheng Che Zhi-liang ning Hong-Bo Fan Jian-Fei Sun Yong-Jiang Huang Alfonso H.W.Ngan National Key Laboratory for Precision Hot Processing of Metals Harbin Institute of TechnologyHarbin 150001China Space Environment Simulation Research Infrastructure Harbin Institute of TechnologyHarbin 150001China Department of Mechanical Engineering The University of Hong KongHong Kong 999077China

The distinctive intrinsic heat treatment(IHT)originating from cyclic reheating in the laser-directed energy deposition(LDED) has attracted growing attention in recent *** this investigation,simulations and experimental characterizations were performed to examine the impact of IHT on the micros true ture and mechanical properties of LDED-fabricated CrCoNi medium-entropy alloy(MEA).The results show that the intensity of the IHT is proportional to the utilized laser energy density(LED).As the LED increased,significant dynamic recrystallization and grain refinement occurred within the alloy due to the enhanced intensity of ***,the high LED leads to severe hot cracking within the as-built MEA,resulting in inferior *** decreasing LED,the hot cracking was effectively ***,low LED weakened the intensity of IHT and consequently inhibited kinetic conditions of dynamic recrystallization,resulting in a heterogeneous grain structure characterized by multi-scale-sized *** structure provides significant hetero-deformation-induced hardening during plastic deformation,enabling the alloy to have a sustainable work-hardening *** expect that this work will have implications in taking full advantage of the unique IHT of the LDED process to fabricate ME As with excellent metallurgical quality and mechanical performance.

关键词： Intrinsic heat treatment Laser-directed energy deposition CrCoNi MEA Dynamic recrystallization Heterogeneous grain structure

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活性元素镁对铝合金真空钎焊接头性能的影响

焊接学报 2007年第7期28卷 61-64页

作者：梁宁沈以赴中国电子科技集团公司第三十八研究所合肥230031 南京航空航天大学材料科学与技术学院南京210016

采用真空钎焊方法对3A21铝合金进行了试验,针对固态高纯镁在真空下加热挥发的特性,试验研究了炉膛中放置不同质量的活性元素镁对铝合金真空钎焊接头性能的影响。采用材料万能试验机和金相显微镜获得并分析了接头力学性能和显微组织。结... 详细信息

采用真空钎焊方法对3A21铝合金进行了试验,针对固态高纯镁在真空下加热挥发的特性,试验研究了炉膛中放置不同质量的活性元素镁对铝合金真空钎焊接头性能的影响。采用材料万能试验机和金相显微镜获得并分析了接头力学性能和显微组织。结果表明,比较炉膛内放置三种不同质量镁的钎缝抗剪强度,当单位体积镁质量达到235g/m3时其强度最高,达到78MPa;金相组织显示,真空钎焊接头中主要强化相为Mg2Si,单位体积镁质量达到235g/m3时钎缝区宽度最小,约0.06mm;通过获取不同产品在325℃以上的停留时间,可定量掌握炉膛预置固态镁质量。

关键词：活性元素真空钎焊力学性能

Microstructure and elevated-temperature tensile properties of differential pressure sand cast Mg-4Y-3Nd-0.5Zr alloy

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China Foundry 2016年第1期13卷 30-35页

作者： Hong-hui Liu Zhi-liang ning Hai-chao Sun Fu-yang Cao Hao Wang Xin-yi Zhao Jian-fei Sun School of Materials Science and Engineering Harbin Institute of Technology Harbin 150001 China Harbin Dongan Engine (Group) Co. Ltd. Harbin 150066 China National Key Laboratory for Precision Hot Processing of Metals Harbin Institute of Technology Harbin 150001 China

The microstructures of an Mg-4Y-3Nd-0.5Zr alloy by differential pressure casting were investigated using scanning electron microscopy （SEM） and transmission electron microscopy （TEM）, and its tensile deformation behavior was measured using a Gleeble1500D themo-simulation machine in the temperature range of 200 to 400 ℃ at initial strain rates of 5×10^-4 to 10^-1 s^-1. Results show that the as-cast microstructure consists of primary α-Mg phase and bone-shaped Mg5RE eutectic phase distributed along the grain boundary. The eutectic phase is dissolved into the matrix after solution treatment and subsequently precipitates during peak aging. Tensile deformation tests show that the strain rate has little effect on stress under 300 ℃. Tensile stress decreases with an increase in temperature and the higher strain rate leads to an increase in stress above 300 ℃. The fracture mechanism exhibits a mixed quasi-cleavage fracture at 200 ℃, while the fracture above 300 ℃ is a ductile fracture. The dimples are melted at 400 ℃ with the lowest strain rate of 10^-4 s^-1.

关键词： Mg-4Y-3Nd-0.5Zr alloy microstructure mechanical property at elevated temperature fracture