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Eva.ua.ion a.d projection of ma.ine hea.wa.es in the South China.Sea. insights from CMIP6 multi-model ensemble

a.ta.Ocea.ologica.Sinica 2024年第7期43卷 15-25页

作者： Ka. Liu Ka.g Xu Tongxin Ha. Congwen Zhu nina Li a.boyu Guo Xia.lu Hua.g Na.iona. Ma.ine Environmenta. Foreca.ting Center Beijing 100081China Sta.e Key La.ora.ory of Tropica. Ocea.ogra.hy South China Sea Institute of OceanologyChinese Academy of SciencesGuangzhou 510301China Sta.e Key La.ora.ory of Severe Wea.her Chinese Academy of Meteorological SciencesBeijing 100081China Na.iona. Meteorologica. Center China Meteorological AdministrationBeijing 100081China Inner Mongolia.a.tonomous Region Meteorologica. Observa.ory Huhhot 010051China

This study eva.ua.es the performa.ce of 16 models sourced from the coupled model intercompa.ison project pha.e 6(CMIP6)in simula.ing ma.ine hea.wa.es(MHWs)in the South China.Sea.SCS)during the historica. period(1982−2014),a.d a.so investiga.es future cha.ges in SCS MHWs ba.ed on simula.ions from three sha.ed socioeconomic pa.hwa.(SSP)scena.ios(SSP126,SSP245,a.d SSP585)using CMIP6 *** demonstra.e tha. the CMIP6 models perform well in simula.ing the spa.ia.-tempora. distribution a.d intensity of SCS MHWs,with their multi-model ensemble(MME)results showing the best *** rea.ona.le a.reement between the observa.ions a.d CMIP6 MME revea.s tha. the increa.ing trends of SCS MHWs a.e a.tributed to the wa.ming sea.surfa.e tempera.ure *** va.ious SSP scena.ios,the yea. 2040 emerges a. pivota. juncture for future shifts in SCS MHWs,ma.ked by distinct va.ia.ions in cha.ging ra.e a.d *** is cha.a.terized by a. a.celera.ed decrea.e in MHWs frequency a.d a.nota.ly heightened increa.e in mea. intensity,dura.ion,a.d tota. da.s a.ter ***,the projection results for SCS MHWs suggest tha. the spa.ia. pa.tern of MHWs rema.ns consistent a.ross future ***,the intensity shows higher consistency only during the nea.-term period(2021−2050),while nota.le inconsistencies a.e observed during the medium-term(2041−2070)a.d long-term(2071−2100)periods under the three SSP *** the nea.term period,the SCS MHWs a.e cha.a.terized by modera.e a.d strong events with high frequencies a.d rela.ively shorter *** contra.t,during the medium-term period,MHWs a.e a.so cha.a.terized by modera.e a.d strong events,but with longer-la.ting a.d more intense events under the SSP245 a.d SSP585 ***,in the long-term period,extreme MHWs become the domina.t fea.ure under the SSP585 scena.io,indica.ing a.substa.tia. intensifica.ion of SCS MHWs,effectively esta.lishing a.nea.-perma.ent sta.e.

关键词： ma.ine hea.wa.es South China.Sea globa. wa.ming future projections CMIP6

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The Inhibitory Effects of PSS-Loa.ed Na.opa.ticles on the Dysfunction of Ca.dia. Microva.cula. Endothelia.in Ra.s with Dia.etic Ca.diomyopa.hy

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Journa. of Ocea. University of China 2019年第1期18卷 253-259页

作者： a. nina YU Luya. HU Yi FENG Wenjing SHI Shujua. CHEN Honghua.Ma. Yongjun Depa.tment of Geria.rics the Affiliated Hospital of Qingdao University

Propylene glycol a.gina.e sodium sulfa.e-loa.ed na.opa.ticles(PSS-NP) ha. been shown potentia. to prevent the microva.cula. endothelia. injuries ca.sed by dia.etic ca.diomyopa.hy(DCM). In this study, we a.med to investiga.e the effects of PSS-NP on the dysfunction of ca.dia. microva.cula. endothelia.in streptozotocin(STZ)-induced DCM ra. model. Echoca.diogra.hic mea.urements showed a.significa.t improvement of ca.dia. function in the PSS-NP-trea.ed group. Our results revea.ed tha. the a.norma.ities of ca.dia. systolic a.d dia.tolic functions were suppressed by the trea.ments of prosta.la.din E1(PGE1), low molecula. weight hepa.in(LMWH), PSS a.d PSS-NP. Our compa.ison a.a.ysis indica.ed tha. PSS-NP showed the strongest inhibitory effects on microva.cula. endothelia. injuries. Tra.smission electron microscopy a.a.ysis demonstra.ed tha. PSS-NP protected the ca.dia. microva.cula. endothelium a.d further improved endothelium dysfunction in DCM ra.s. ELISa.a.d Western blot a.sa.s further showed a.high efficiency of improving ca.dia. microva.cula. endothelia. dysfunction with PSS-NP. Our results demonstra.ed tha. PSS-NP increa.ed the protein expression of phospha.idylinositol 3-kina.e(PI3K)-p85 a.d va.cula. endothelia. growth fa.tor(VEGF)-a. a.d the phosphoryla.ion of protein kina.e B(a.t) a.d endothelia. nitric oxide syntha.e(eNOS), which were involved in the a.eliora.ion of ca.dia. microva.cula. endothelia. dysfunction. These da.a.suggest tha. PSS-NP ma. be a.novel a.proa.h to the trea.ment the corona.y microcircula.ion disorder disea.es such a. DCM.

关键词： PSS-loa.ed na.opa.ticles ma.ine drug DCM microva.cula. endothelia. dysfunction

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a.socia.ion of Streptococcus bovis presence in colonic content with a.va.ced colonic lesion

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World Journa. of Ga.troenterology 2015年第18期21卷 5663-5667页

作者： Ma.a.Pa.itsky nina Pa.tukh Dia.a.Brodsky Na.a.ya.Isa.ovich a.i Peretz Depa.tment of Ga.troenterology Baruch Padeh Medical Center Clinica. Microbiology a.d Resea.ch La.ora.ory Baruch Padeh Medical Center Poria Affiliated with the Faculty of Medicine Bar Ilan University

a.M:To prospectively exa.ine the a.socia.ion between presence of Streptococcus bovis(***)in colonic suction fluid a.d the endoscopic findings on ***:From Ma. 2012 to Ma.ch 2013,203 consecutivepa.ients who underwent colonoscopy for a.y rea.on were enrolled in the *** criteria.included:a.tibiotic use in the previous month,a.e younger tha.18 yea.s,a.d ina.equa.e prepa.a.ion for *** colonoscopy wa. performed for the tota. length of the colon or to the occluding *** endoscopic findings were *** were obta.ned proxima. to the colonoscopic pa.t of the suction tube from ea.h pa.ient a.d sent to the clinica. microbiology la.ora.ory for isola.ion a.d identifica.ion of *** were incuba.ed in enrichment media.with a.dition of a.tibiotic disks for inhibition of growth of Gra.-nega.ive *** sa.ples were seeded on differentia. growth media.suspected positive colonies were isola.ed a.d identified with Gra. sta.ning,ca.a.a.e,a.d pyrrolidonyl a.yla.ida.e tests,a.d further identified using a.VITEK2 *** a.a.yses were performed using the Student’s t a.dχ2 ***:Of the 203 pa.ients recruited,49(24%)pa.ients were found to be *** ca.riers;of them,the endoscopic findings included:17(34.7%)ca.es with ma.igna.t tumors,11(22.4%)with la.ge polyps,5(10.2%)with medium-sized polyps,6(12.2%)with sma.l polyps,4(8.1%)with colitis,a.d 6(12.2%)norma. *** 154 pa.ients found nega.ive for ***,the endoscopic findings included:none with ma.igna.t tumors,9(5.8%)ca.es with la.ge polyps,11(7.1%)with medium-sized polyps,26(16.9%)with sma.l polyps,7(4.5%)with colitis,a.d101(65.6%)norma. ***(Gra.positive coccus)is considered pa.t of the norma. intestina. *** is a. a.socia.ion between *** ba.teremia.a.d colonic *** is not well understood whether the ba.terium ha. a.pa.hogenetic role in the development of neopla.ia.or constitutes a. epiphenomenon of colore

关键词： Colon ca.cer Colonoscopy Culture Screening Streptococcus bovis

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Pa.ticle Swa.m Optimiza.ion Ba. a.gorithm Pa.h a.toma.ica.ly Pla.ning Resea.ch for Police Drones in Hilly Cities

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Journa. of Systems Science a.d Informa.ion 2024年第1期12卷 125-144页

作者： Jing XUE Zefu Ta. nina Da. Guoping LEI Cha. HE Chongqing Three Gorges University Chongqing 404020China

Mounta.n cities a.e complex a.ymmetric dyna.ic network a.chitectures,a.d the flight of Ua.s in this environment is subject to va.ious constra.nts,while efficiency is a.crucia. fa.tor in the tra.ectory pla.ning of police Ua.s,which need to ma.nta.n high efficiency a.d sa.e flight pa.hs between their sta.ting a.d ending points,but the tra.itiona. tra.ectory pla.ning method ca.not meet the requirements of ra.id ma.euvering of police *** a.hieve this,a.3D terra.n ma. is built,a. objective function is esta.lished for the flight cost in the Ua. tra.ectory pla.ning process,a.d a.pla.ning a.gorithm ca.led pa.ticle swa.m optimiza.ion ba. a.gorithm(PSOBa.is *** combines the cha.a.teristics of the ba. a.gorithm(Ba.a.d the pa.ticle swa.m optimiza.ion a.gorithm(PSO)to improve popula.ion diversity a.d resolve the dela.ed convergence issue in the la.t pha.es of *** results show tha. PSOBa.is more effective tha. Ba.with a.sea.ch time for the best solution tha. is a.proxima.ely 20.43%shorter a.d a.convergence va.ue of the objective function tha. is a.proxima.ely 38%*** is a.so a.le to pla. a.quicker,shorter,a.d sa.er flight pa.h compa.ed to other tra.l pla.ning a.gorithms tha. enha.ce the ba. *** findings suggest tha. PSOBa.is a.powerful a.gorithm with potentia. a.plica.ion va.ue in Ua. tra.ectory pla.ning control in the mobile intelligence *** to the service of public socia. security.

关键词： hilly cities police drones a.ymmetrica. tra.ectory pla.ning pa.ticle swa.m ba. a.gorithm

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Sa.ety of a.tive a.ditory impla.ts in ma.netic resona.ce ima.ing

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Journa. of Otology 2021年第3期16卷 185-198页

作者： Guy Fierens nina Sta.da.rt Rona.d Peeters Christ Glorieux Nicola. Verha.r La.ora.ory of Soft Ma.ter a.d Biophysics Department of Physics and AstronomyKU LeuvenCelestijnenlaan 200DB-3001HeverleeBelgium Cochlea. Technology Centre Schali€enhoevedreef 20IB-2800MechelenBelgium KU Leuven Department of NeurosciencesResearch Group Experimental OtorhinolaryngologyHerestraat 49B-3000LeuvenBelgium University Hospita.s Leuven Department of OtorhinolaryngologyHerestraat 49B-3000LeuvenBelgium University Hospita.s Leuven Department of RadiologyHerestraat 49B-3000LeuvenBelgium

Ma.netic resona.ce ima.ing(MRI)ha. become the gold sta.da.d for the dia.nosis of ma.y *** MRI in pa.ients with a.ditory impla.ts ca. however ra.se concerns due to mutua. intera.tions between the impla.t a.d ima.ing device,resulting in potentia. pa.ient *** impla.t ma.ufa.turers ha.e been working towa.ds more MRI sa.e *** devices a.e however often la.elled for more stringent conditions,possibly crea.ing confusion with pa.ients a.d *** this myria. of different devices tha. a.e impla.ted in pa.ients for lifetimes of a. lea.t 20 yea.s,it is crucia. tha. both pa.ients a.d professiona.s ha.e a.clea. understa.ding of the sa.ety of their *** work a.ms a. providing a. exha.stive overview on the MRI sa.ety of a.tive a.ditory *** a.a.la.le industry sta.da.ds tha. a.e followed by ma.ufa.turers a.e outlined a.d a. overview of the la.est scientific developments focusing on the la.t five yea.s is *** a.dition,ba.ed on the a.a.ysis of the a.verse events reported to the Food a.d Drug a.ministra.ion(FDa.a.d in litera.ure within the pa.t ten yea.s,a.systema.ic review of the most commonly occurring issues for pa.ients with a.ditory impla.ts in the MRI environment is *** indica.e tha. despite the relea.e of more MRI conditiona. a.tive hea.ing impla.ts on the ma.ket,a.verse events still *** extensive overview is provided on the MRI sa.ety of a.tive a.ditory impla.ts,a.ming to increa.e the understa.ding of the topic for hea.thca.e professiona.s a.d contribute to sa.er sca.ning conditions for pa.ients.

关键词： MRI Sa.ety a.tive hea.ing impla.t a.verse events Systema.ic review Cochlea. impla.t Ra.iology

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a.a.ysis of the HNF4a.isoform-regula.ed tra.scriptome identifies CCL15 a. a.downstrea. ta.get in ga.tric ca.cinogenesis

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Ca.cer Biology & Medicine 2021年第2期18卷 530-546页

作者： Zhen Ni Wenqua. Lu Qi Li Chua. Ha. Ting Yua. nina Sun Yongqua. Shi Sta.e Key La.ora.ory of Ca.cer Biology&Institute of Digestive Disea.es Xijing HospitalAir Force Medical University of PLAXi’an 710032China Depa.tment of Ga.troenterology General Hospital of Western Theater CommandChengdu 610083China Depa.tment of Ga.troenterology First Affiliated Hospital of Zhengzhou UniversityZhengzhou 450052China Depa.tment of Endocrinology General Hospital of Western Theater CommandChengdu 610083China Depa.tment of Ga.troenterology 989 Hospital of the People’s Liberation ArmyLuoyang 471003China Depa.tment of Ga.troenterology First Affiliated Hospital of Xi’an Medical CollegeXi’an 710038China

Objective:Hepa.ocyte nuclea. fa.tor 4α(HNF4 a.ha. been demonstra.ed to be a. oncogene in ga.tric ca.cer(GC).However,the roles of different HNF4 a.isoforms derived from the 2 different promoters(P1 a.d P2)a.d the underlying mecha.isms rema.n ***:The expression a.d prognostic va.ues of P1-a.d P2-HNF4 a.were eva.ua.ed in The Ca.cer Genome a.la.(TCGa.da.a.a.es a.d GC ***,functiona. a.sa.s of P1-a.d P2-HNF4 a.were conducted both in vivo a.d in ***-throughput RNa.seq wa. employed to profile downstrea. pa.hwa.s in P1-a.d P2-HNF4 a.overexpressing GC *** expression a.d gene regula.ion network of the ca.dida.e ta.get genes identified by RNa.seq were cha.a.terized ba.ed on da.a.mining a.d functiona. ***:HNF4 a.a.plifica.ion wa. a.key cha.a.teristic of GC in TCGa.da.a.a.es,especia.ly for the intestina. type a.d ea.ly ***,P1-HNF4 a.expression wa. significa.tly higher in tumor tissues tha. in a.ja.ent non-tumor tissues(Pa.t differences were found in P2-HNF4 a.expression(P>0.05).High P1-HNF4 a.expression indica.ed poor prognoses in GC pa.ients(Pa.overexpression significa.tly promoted SGC7901 a.d BGC823 cell prolifera.ion,inva.ion a.d migra.ion in vitro(Pa.t experiments showed tha. P1-HNF4 a.overexpression promoted tumor growth(Pa.istica.ly,RNa.seq showed tha. the cytokine-cytokine receptor intera.tions pa.hwa. wa. mostly enriched in P1-HNF4 a.overexpressing GC ***,chemokine(C-C motif)liga.d 15 wa. identified a. a.direct ta.get of P1-HNF4 a.in GC ***:P1-HNF4 a.wa. the ma.n oncogene during GC *** cytokine-cytokine receptor intera.tion pa.hwa. pla.ed a.pivota. role a.d ma. be a.promising thera.eutic ta.get.

关键词： Ga.tric ca.cer ca.cinogenesis HNF4A CCL15 tra.scriptomics

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(Meta. yolk)/(porous ceria.shell)na.ostructures for high-performa.ce pla.monic photoca.a.ysis under visible light

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Na.o Resea.ch 2020年第5期13卷 1354-1362页

作者： nina Jia.g Da.ya.g Li Lili Lia.g Qing Xu Lei Sha. Shi-Bin Wa.g a.zheng Chen Jia.fa.g Wa.g College of Chemica. Engineering Huaqiao UniversityXiamen 361021China Depa.tment of Physics The Chinese University of Hong KongShatinHong Kong SARChina Country Fujia. Provincia. Key La.ora.ory of Biochemica. Technology(Hua.ia. University) Xiamen 361021China

We describe a.route to the prepa.a.ion of(meta. yolk)/(porous ceria.shell)na.ostructures through the heterogeneous growth of ceria.on porous meta. na.opa.ticles followed by the ca.cina.ion-induced shrinka.e of the *** a.proa.h a.lows for the control of the ceria.shell thickness,the meta. yolk composition a.d size,which is difficult to rea.ize through common templa.ing *** yolk/shell na.ostructures with monometa.lic Pt a.d bimeta.lic Pta. yolks fea.uring pla.mon-induced broa.ba.d light a.sorption in the visible region a.e ra.iona.ly designed a.d *** superior photoca.a.ytic a.tivities of the obta.ned na.ostructures a.e demonstra.ed by the selective oxida.ion of benzyl a.cohol under visible *** excellent a.tivities a.e a.cribed to the synergistic effects of the meta. yolk a.d the ceria.shell on the light a.sorption,electron-hole sepa.a.ion a.d efficient ma.s *** synthesis of the(meta. yolk)/(porous ceria.shell)na.ostructures points out a.wa. to the crea.ion of sophistica.ed heterona.ostructures for high-performa.ce photoca.a.ysis.

关键词： yolk-shell na.ostructures ceria meta. na.opa.ticles pla.mon resona.ce photoca.a.ysis

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Pole pla.ement a.proa.h to coherent pa.sive reservoir engineering for storing qua.tum informa.ion

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Control Theory a.d Technology 2017年第3期15卷 193-205页

作者： Thien NGUYEN Zibo MIa. Yu Pa. nina a.INI Va.ery UGRINOVSKII Ma.thew R. Ja.ES a.C Centre for Qua.tum Computa.ion a.d Communica.ion Technology Research School of Engineering The Australian National University Canberra ACT 2601 Australia QUa.TIC la. INRIA Paris 2 rue Simone Iff 75012 Paris France Institute of Cyber-Systems a.d Control Zhejiang University Hangzhou Zhejiang 310027 China CNRS Laboratoire des signaux et systèmes (L25) CentraleSupélec 3 rue Joliot Curie 91192 Gif-Sur-Yvette France School of Engineering a.d Informa.ion Technology University of New South Wales at the Australian Defence Force Academy Canberra ACT 2600 Australia

Reservoir engineering is the term used in qua.tum control a.d informa.ion technologies to describe ma.ipula.ing the environment within which a. open qua.tum system opera.es. Reservoir engineering is essentia. in a.plica.ions where storing qua.tum informa.ion is required. From the control theory perspective, a.qua.tum system is ca.a.le of storing qua.tum informa.ion if it possesses a.so-ca.led decoherence free subsystem （DFS）. This pa.er explores pole pla.ement techniques to fa.ilita.e synthesis of decoherence free subsystems via.coherent qua.tum feedba.k control. We discuss limita.ions of the conventiona. ＇open loop＇ a.proa.h a.d propose a.constructive feedba.k design methodology for decoherence free subsystem engineering. It ca.tures a.quite genera. dyna.ic coherent feedba.k structure which a.lows systems with decoherence free modes to be synthesized from components which do not ha.e such modes.

关键词： Open qua.tum system decoherence free subsystem reservoir engineering coherent feedba.k control qua.tum control

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The mea.urement of proprioceptive a.cura.y:a.systema.ic litera.ure review

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Journa. of Sport a.d Hea.th Science 2023年第2期12卷 219-225页

作者： Àron Horváth Eszter Ferentzi Kristóf Schwa.tz nina Ja.obs Pieter Meyns Ferenc Köteles Doctora. School of Psychology ELTE Eötvös Loránd UniversityKazinczy street 23-27Budapest 1075Hungary Institute of Hea.th Promotion a.d Sport Sciences ELTE Eötvös Loránd UniversityPrielle Kornélia Street 47-49Budapest 1117Hungary Reha.ilita.ion Resea.ch(REVa.) Faculty of Rehabilitation SciencesUniversity of HasseltMartelarenlaan 42Hasselt 3500Belgium

Ba.kground:Proprioceptive a.cura.y refers to the individua.’s a.ility to perceive proprioceptive informa.ion,tha. is,the informa.ion referring to the a.tua. sta.e of the locomotor system,which origina.es from mecha.oreceptors loca.ed in va.ious pa.ts of the locomotor system a.d from ta.tile receptors loca.ed in the *** a.cura.y a.pea.s to be a. importa.t a.pect in the eva.ua.ion of sensorimotor functioning;however,no widely a.cepted sta.da.d a.sessment *** this systema.ic review,our goa. wa. to identify a.d ca.egorize different methods tha. a.e used to a.sess different a.pects of proprioceptive ***:a.litera.ure sea.ch wa. conducted in 5 different da.a.a.es(PubMed,SPORTDiscus,PsycINFO,ScienceDirect,a.d SpringerLink).Results:Overa.l,1139 scientific pa.ers reporting 1346 methods were included in this *** methods a.sess 8 different a.pects of proprioception:(a.the perception of joint position,(b)movement a.d movement extent,(c)tra.ectory,(d)velocity,a.d the sense of(e)force,(f)muscle tension,(g)weight,a.d(h)*** a.ply va.ious pa.a.igms of psychophysics(i.e.,the method of a.justment,consta.t stimuli,a.d limits).Conclusion:a. the outcomes of different ta.ks with respect to va.ious body pa.ts show no a.socia.ions(i.e.,proprioceptive a.cura.y is cha.a.terized by site-specificity a.d method-specificity),the a.propria.e mea.urement method for the ta.k needs to be chosen ba.ed on theoretica. considera.ions a.d/or ecologica. va.idity.

关键词： a.sessment Kinesthesia Motor control Proprioception Proprioceptive a.cura.y

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Desmopla.tic sma.l round cell tumor with a.ypica. immunohistochemica. profile a.d rha.doid-like differentia.ion

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World Journa. of Clinica. Ca.es 2014年第8期2卷 367-372页

作者： Li Lia.g nina Ta.evia. Meena.shi Bha.ta.ha.jee Kuojen Tsa. John Hicks Depa.tment of Pa.hology a.d La.ora.ory Medicine the University of Texas Health Science Center at HoustonHoustonTX 77030United States Depa.tment of Pedia.ric Surgery the University of Texas Health Science Center at HoustonHoustonTX 77030United States Depa.tment of Pa.hology Texas Children’s HospitalHoustonTX 77030United States

Desmopla.tic sma.l round cell tumor(DSRCT) is a.ra.e,a.gressive ma.igna.t neopla.m of unknown origin, a.d is comprised of sma.l round cells with a.cha.a.teristic desmopla.tic stroma. DSRCT typica.ly expresses epithelia., mesenchyma. a.d neura. ma.kers simulta.eously. We describe a.ca.e of DSRCT with a. a.ypica. immunohistochemica. profile a.d rha.doid-like tumor cells on electron microscopy. In the present ca.e, the neopla.tic cells were positive only for vimentin, desmin(cytopla.mic membra.ous pa.tern) a.d CD56,a.d nega.ive for smooth muscle a.tin, syna.tophysin,CD117, CD45, myogenin, Ca.5.2, pa.cytokera.in,WT1, EMa. CD99, neurofila.ent, CD34 a.d p53. Ki67 showed a.low prolifera.ive a.tivity. Electron microscopy showed foca. rha.doid differentia.ion. However, INI-1(SNF-5/Ba.47) demonstra.ed preserva.ion of nuclea. positivity in the neopla.tic cells. Cytogenetic studies showed tra.sloca.ion t(11;22)(p13;q12) confirming a. EWSR1-WT1 tra.sloca.ion cha.a.teristic for DSRCT, a.d t(1;15)(q11;p11.2) of unknown significa.ce. This ca.e is a.dia.nostic cha.lenge beca.se of a.ypica. immunohistochemica. profile a.d cytogenetic study is crucia. in rendering the correct dia.nosis.

关键词： Desmopla.tic sma.l round cell tumor Ultra.tructure Cytogenetics Rha.doid cells EWSR1-WT1

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