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A Case Report: Emergency Management of a Pregnant Trauma Patient—An Anesthesiologist’s Perspective and Role

Open Journal of Anesthesiology 2024年第2期14卷 25-39页

作者： Kalpana Tyagaraj Candice Ibarra Kimberly Moy nina Luksanapol Gianna Torre Raymond Powers Anuj Bapodra Maimonides Medical Center New York USA

Trauma is the leading cause of death for all women of childbearing age. Motor vehicle accidents account for almost two-thirds of all maternal non-obstetric, trauma-related deaths, while falls and domestic violence comprise a large percentage of the rest. The leading causes of obstetric trauma are motor vehicle accidents, falls, assaults, and gunshots, and ensuing injuries are classified as blunt abdominal trauma, pelvic fractures, or penetrating trauma . The causes are different with different life styles and different socio-economic and cultural background. Pregnant trauma victims tend to be younger, less severely injured, and more likely African American or of Hispanic descent compared with nonpregnant victims of trauma. Drugs and alcohol are a factor in about 20 percent of maternal trauma. With pregnancy comes the challenge and responsibility of caring for two patients at once, the mother and the fetus. In general, providing optimal maternal care is the best strategy to optimize fetal survival. Decision-making including the condition of the mother, gestational age, status of the fetus, and interventions are based on these key factors. Many providers are involved in the care of the pregnant patient: at the trauma scene, in the emergency department, and in the operating room. The anesthesiologist plays a key role in the care and management of the pregnant trauma patient. All anesthesiologists have ample training in obstetric anesthesia during their residency and frequently cover obstetric units in hospitals where pregnant patients are cared for. On the other hand, most nonobstetric physicians have little obstetric exposure and may be uncomfortable caring for the pregnant patient because of unfamiliarity with the physiologic changes of pregnancy or the evaluation of fetal well-being. This is not only a source of stress for other trauma providers, but can put maternal well-being at risk. Non-obstetric physicians may hesitate to order necessary diagnostic and therapeu

关键词： Obstetric Anesthesiology Ob Trauma Maternal and Fetal Resuscitation

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在巴厘岛享受甜品带来的美好瞬间

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旅行者 2024年第2期 86-87页

作者： nina The Mulia(图) 不详

2024年伊始,精品法式甜品店Cannele在位于印度尼西亚的巴厘岛穆丽雅酒店、穆丽雅度假村及别墅内的奢华空间盛大开业,开启了一段重新定义纵情享受甜品艺术的旅程。这家店铺不仅是一家甜品店,还是一处汇聚了精致手工蛋糕、西点、设计师蛋... 详细信息

2024年伊始,精品法式甜品店Cannele在位于印度尼西亚的巴厘岛穆丽雅酒店、穆丽雅度假村及别墅内的奢华空间盛大开业,开启了一段重新定义纵情享受甜品艺术的旅程。这家店铺不仅是一家甜品店,还是一处汇聚了精致手工蛋糕、西点、设计师蛋糕以及新鲜出炉面包的艺术殿堂,同时也提供品类齐全的咖啡、茶与精选葡萄酒,为每一位来到穆丽雅酒店的旅行者带来无与伦比的奢华美味体验。

关键词：甜品葡萄酒蛋糕艺术殿堂旅行者巴厘岛西点酒店

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Biallelic variants in RBM42 cause a multisystem disorder with neurological,facial,cardiac,and musculoskeletal involvement

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Protein & Cell 2024年第1期15卷 52-68页

作者： Yiyao Chen Bingxin Yang Xiaoyu Merlin Zhang Songchang Chen Minhui Wang Liya Hu nina Pan Shuyuan Li Weihui Shi Zhenhua Yang Li Wang Yajing Tan Jian Wang Yanlin Wang Qinghe Xing Zhonghua Ma Jinsong Li He-Feng Huang Jinglan Zhang Chenming Xu Institutes of Biomedical Sciences Fudan UniversityShanghai 200032China bstetrics and Gynecology Hospital Institute of Reproduction and DevelopmentFudan UniversityShanghai 200011China Intermational Peace Matermity and Child Health Hospital School of MedicineShanghai Jiao Tong UniversityShanghai 200030China Shanghai Key Laboratory of Embryo Original Diseases Shanghai 200030China State Key Laboratory of Cell Biology Shanghai Key Laboratory of Molecular AndrologyShanghai Institute of Biochemistry and Cell BiologyCAS Center for Excellence in Molecular Cell ScienceUniversity of Chinese Academy of SciencesChinese Academy of SciencesShanghai 200031China State Key Laboratory of Rice Biology the Key Laboratory of Molecular Biology of Crop Pathogens and InsectsInstitute of BiotechnologyZhejiang UniversityHangzhou 310058China Verna and Marrs McLean Department of Biochemistry and Molecular Biology Baylor College of MedicineHoustonTX 77030USA Children's hospital of Fudan University Shanghai 201102China School of Life Science and Technology Shanghai Tech UniversityShanghai 201210China School of Life Science Hangzhou Institute for Advanced StudyUniversity of Chinese Academy of SciencesHangzhou 310024ZhejiangChina Research Units of Embryo Original Diseases Chinese Academy of Medical Sciences(No.2019RU056)Shanghai 200011China

Here,we report a previously unrecognized syndromic neurodevelopmental disorder associated with biallelic loss-of-function variants in the RBM42 *** patient is a 2-year-old female with severe central nervous system(CNs)abnormalities,hypotonia,hearing loss,congenital heart defects,and dysmorphic facial *** whole-exome sequencing(WEs)reveals that the patient has two compound heterozygous variants,c.304C>T(p.R102*)and c.1312G>A(p.A438T),in the RBM42 gene which encodes an integral component of splicing complex in the RNA-binding motif protein *** p.A438T variant is in the RRM domain which impairs RBM42 pro-tein stability in ***,p.A438T disrupts the interaction of RBM42 with hnRNP K,which is the causa-tive gene for Au-Kline syndrome with overlapping disease characteristics seen in the index *** human R102*or A438T mutant protein failed to fully rescue the growth defects of RBM42 ortholog knockout△FgRbp1 in Fusarium while it was rescued by the wild-type(WT)human RBM42.A mouse model carying Rbm42 compound heterozygous variants,c.280C>T(p.Q94*)and c.1306_1308delinsACA(p.A436T),demonstrated gross fetal develop-mental defects and most of the double mutant animals died by ***-seq data confirmed that Rbm42 was involved in neurological and myocardial functions with an essential role in alternative splicing(As).Overall,we present clinical,genetic,and functional data to demonstrate that defects in RBM42 constitute the underlying etiology of a new neurodevelopmental disease which links the dysregulation of global AS to abnormal embryonic development.

关键词： RBM42 gene RNA-binding protein neurodevelopmental disorder Au-Kline syndrome alternative splicing

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A Case Report of Kissing Molars Class II

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Open Journal of Stomatology 2024年第5期14卷 249-254页

作者： Toshiyuki Inou Keiichi Uchida Keiko Kaneko Anna Fuji nina Wakimoto Tatsuo Takaya Hiroyuki Kitamura Hiroshi Mori Yuji Kurihara Department of Oral Diagnostics and Comprehensive Dentistry Matsumoto Dental University Hospital Shiojiri Japan Department of Oral and Maxillofacial Surgery School of Dentistry Matsumoto Dental University Shiojiri Japan

Kissing molars (KMs) is a condition of occlusal molar surfaces in a single follicular space with roots extending in opposite directions. Here, we have reported a case of KMs in a 58-year-old woman. The patient complained of pain in the right mandibular molar region and was diagnosed with KMs consisting of the right mandibular second and third molars. Because of the patient’s pain having subsided at the time of the visit and her unwillingness to undergo tooth extraction, the patient was followed up. KMs is classified into three classes (I-III) and is either true-KMs or pseudo-KMs and presents with or without cystic variants of dental follicles. The presents as true-KMs class II without a cystic variant. With reference to the literature and based on our analysis, the mean age of patients affected by this specific case of KMs is 31.7 years and unilateral KMs is relatively more common (85.7%). Histopathological findings of dentigerous cysts are more often indicated (42.9%). The treatment policy for KMs should therefore be based on the classification of KMs. Importantly, the focus should be on preserving the first and second molars as much as possible. The treatment approach, such as the employment of surgical removal or orthodontics, should be determined by considering the associated factors such as the crowns, tissues, and age of the patient.

关键词： Kissing Molars Mandibular Second Molar Mandibular Third Molar Cone-Beam Computed Tomography

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Chest Radiography: General Practitioners’ Compliance with Recommendations

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Open Journal of Medical Imaging 2024年第2期14卷 56-63页

作者： Milckisédek Judicaël Marouruana Some Aïda Ida Tankoano Pakisba Ali Ouedraogo Bassirou Kindo nina-Astrid Ouedraogo Mohammed Ali Harchaoui Department of Medical Imaging The Ouahigouya Regional University Hospital University of Ouahigouya Ouahigouya Burkina Faso Department of Medical Imaging Souro Sanou University Hospital Nazi Boni University Bobo Dioulasso Burkina Faso Department of Medical Imaging Bogodogo University Hospital Joseph Ki Zerbo University Ouagadougou Burkina Faso Private Radiologist Lille France

Introduction: Chest radiography is the most frequently prescribed imaging test in general practice in France. We aimed to assess the extent to which general practitioners follow the recommendations of the French National Authority for Health in prescribing chest radiography. Methodology: We conducted a retrospective analysis study, in two radiology centers belonging to the same group in Saint-Omer and Aire-sur-la-Lys, of requests for chest radiography sent by general practitioners over the winter period between December 22, 2013, and March 21, 2014, for patients aged over 18 years. Results: One hundred and seventy-seven requests for chest X-rays were analyzed, 71.75% of which complied with recommendations. The most frequent reason was the search for bronchopulmonary infection, accounting for 70.08% of prescriptions, followed by 11.2% for requests to rule out pulmonary neoplasia, whereas the latter reason did not comply with recommendations. Chest X-rays contributed to a positive diagnosis in 28.81% of cases. The positive diagnosis was given by 36.22% of the recommended chest X-rays, versus 10% for those not recommended. Conclusion: In most cases, general practitioners follow HAS recommendations for prescribing chest X-rays. Non-recommended chest X-rays do not appear to make a major contribution to diagnosis or patient management, confirming the value of following the recommendations of the French National Authority for Health.

关键词： Chest X-Ray Recommendations General Practitioners Prescription

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高温后再生保温混凝土损伤劣化数值分析

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太原理工大学学报 2024年第5期55卷 892-904页

作者：刘淑钰苗艳春李明厚李贝贝 SELYUTINA nina SMIRNOV Ivan 刘元珍张玉太原理工大学土木工程学院太原030024 Saint Petersburg State University St.Petersburg 199034Russia

【目的】内部多孔且高温稳定的玻化微珠(glazed hollow beads,GHB)可在一定程度上减缓混凝土的高温损伤劣化,提升混凝土的抗火性能。为了进一步明确GHB改善混凝土抗火性能的机理,从细观尺度出发,提出一种可考虑初始缺陷和再生骨料(recyc... 详细信息

【目的】内部多孔且高温稳定的玻化微珠(glazed hollow beads,GHB)可在一定程度上减缓混凝土的高温损伤劣化,提升混凝土的抗火性能。为了进一步明确GHB改善混凝土抗火性能的机理,从细观尺度出发,提出一种可考虑初始缺陷和再生骨料(recycled coarse aggregate,RCA)取代率的再生保温混凝土(recycled aggregate concrete mixed with glazed hollow beads,RATIC)细观模型的建模方法。【方法】利用现阶段比较常用的塑性损伤模型,探究了RCA取代率(0,50%,100%)、GHB含量(0,70%,100%)和孔隙率(0,2%,4%)对于高温后RATIC力学性能的影响。【结果】结果表明:随着受火温度的提高,荷载作用下RATIC试件的损伤分布均呈现出逐渐加剧的趋势,且500℃后,试件的损伤分布较400℃之前严重。GHB的加入可在一定程度上缓减混凝土内部的损伤劣化,而RCA的加入会加剧此现象。此外,随着孔隙率增大,RATIC试件的强度逐渐变低。

关键词：再生保温混凝土随机骨料模型单轴抗压高温孔隙率

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一种融合局部异常因子的矢量建筑物群聚类方法

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武汉大学学报（信息科学版） 2024年第4期49卷 562-571页

作者：孟妮娜王正阳高晨博李金秋长安大学地质工程与测绘学院陕西西安710054

地形图中建筑物群聚类特征的挖掘对实现自动制图综合和空间知识挖掘具有重要意义,而识别城市中不同分布密度、不同形态特征的建筑物多边形群落存在较大难度。提出了一种融合局部异常因子(local outlier factor,LOF)的聚类方法,以建筑物... 详细信息

地形图中建筑物群聚类特征的挖掘对实现自动制图综合和空间知识挖掘具有重要意义,而识别城市中不同分布密度、不同形态特征的建筑物多边形群落存在较大难度。提出了一种融合局部异常因子(local outlier factor,LOF)的聚类方法,以建筑物的邻接图为基础,根据相邻建筑物之间的形态因子差异和邻近距离构建特征向量,使用LOF算法动态计算特征向量的异常程度,剔除异常向量,最终得到建筑物聚类簇。选取中国上海市和长春市的建筑物数据对该方法进行了验证,通过调整LOF值上限和K邻近数取得了最终聚类结果,实验结果表明,该方法能够有效识别和区分城市中密集分布的建筑物群。为解决城市密集建筑物群聚类问题提供了新思路,验证了格式塔准则的重要性,聚类结果达到了与人类视觉认知相符的效果。

关键词：矢量建筑物多边形空间聚类局部异常因子邻接图邻近距离

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聚焦波下漂浮式风机气动特性数值分析

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水动力学研究与进展（A辑） 2024年第2期39卷 154-164页

作者：薛瑛杰王尼娜万德成上海交通大学船舶海洋与建筑工程学院船海计算水动力学研究中心(CMHL) 上海200240 中国电建集团华东勘测设计研究院有限公司浙江省深远海风电技术研究重点实验室杭州310014

该文基于计算流体力学方法,对极端海况聚焦波作用下的漂浮式风机运动响应与气动特性进行研究。首先,依托开源软件OpenFOAM与自研求解器FOWT-UALM-SJTU,实现了面向双参数PM波浪谱聚焦波的数值模拟,并与试验结果进行比较验证,吻合良好。随... 详细信息

该文基于计算流体力学方法,对极端海况聚焦波作用下的漂浮式风机运动响应与气动特性进行研究。首先,依托开源软件OpenFOAM与自研求解器FOWT-UALM-SJTU,实现了面向双参数PM波浪谱聚焦波的数值模拟,并与试验结果进行比较验证,吻合良好。随后,在两种不同聚焦幅值工况下,以OC3 Spar型漂浮式风机平台及NREL 5 WM风机作为研究对象,开展气动-水动-系泊一体化仿真计算,对聚焦波作用下的漂浮式风机运动响应和气动性能进行分析。结果表明:聚焦波将引起风机在纵摇运动与垂荡运动时产生剧烈响应,风机叶片展向的气动攻角在聚焦时刻显著降低,风机气动功率与气动推力难以在短时间内恢复;同时,聚焦波将导致尾流中心和边界出现波动,极端波浪条件将扩大风机尾流速度亏损范围,对下游风机产生不利影响。

关键词：聚焦波漂浮式风机数值模拟气动性能尾流亏损

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晚第四纪构造与气候控制下的金沙江支流巴楚河阶地序列

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地质科学 2024年第1期59卷 224-234页

作者：刘妮娜田开飞刘博温凯长安大学西部矿产资源与地质工程教育部重点实验室西安710054 长安大学地质工程与测绘学院西安710054 安徽省交通规划设计研究总院股份有限公司合肥230000

河流阶地的形成过程研究是理解地区气候变化、构造隆升过程的重要手段。巴楚河地处青藏高原东南缘,隶属于金沙江支流水系,两岸阶地发育。因其独特的地理位置,为第四纪以来青藏高原的隆升研究提供了天然场地条件,对该地区金沙江水系的形... 详细信息

河流阶地的形成过程研究是理解地区气候变化、构造隆升过程的重要手段。巴楚河地处青藏高原东南缘,隶属于金沙江支流水系,两岸阶地发育。因其独特的地理位置,为第四纪以来青藏高原的隆升研究提供了天然场地条件,对该地区金沙江水系的形成演化过程的研究也具有重要补充作用。野外勘查发现,巴楚河发育有四级阶地。对阶地堆积物进行宇宙成因核素测年和光释光测年,得到T1~T4阶地形成时代分别为1.7±0.1 ka、2.3±0.21 ka、4.5±0.5 ka和62.3±2 ka。T4阶地的形成主要为构造活动因素影响,T1~T3阶地的形成和阶地沉积物的堆积主要与气候有关。通过对阶地的拔河高度和形成时代的分析得巴楚河阶地下切速率由慢到快再平稳。研究结果对巴塘地区气候变化及构造运动历史的研究提供重要依据,促进了该地区金沙江水系形成演化的研究,与前人对青藏高原全新世以来隆升过程的研究相互呼应。

关键词：河流阶地沉积年代巴楚河青藏高原

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Influence of Waveguide Properties on Wave Prototypes Likely to Accompany the Dynamics of Four-Wave Mixing in Optical Fibers

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Journal of Applied Mathematics and Physics 2024年第7期12卷 2601-2633页

作者： Jean Roger Bogning Marcelle nina Zambo Abou’ou Christian Regis Ngouo Tchinda Mathurin Fomekong Oriel Loh Ndichia Stallone Mezezem Songna François Béceau Pelap Department of Physics Higher Teacher Training College University of Bamenda Bamenda Cameroon African Optical Fiber Family Bafoussam Cameroon Department of Physics Faculty of Science University of Bamenda Bamenda Cameroon Department of Physics Faculty of Science University of Yaound I Yaound Cameroon Africain en Technologie de lInformation et de la Tlcommunication The University of Yaound I Yaound Cameroon Unit de Recherche de Mcanique et de Modlisation des Systmes Physiques (UR-2MSP) Facult des Sciences Universit de Dschang Dschang Cameroun

In this article, we study the impacts of nonlinearity and dispersion on signals likely to propagate in the context of the dynamics of four-wave mixing. Thus, we use an indirect resolution technique based on the use of the iB-function to first decouple the nonlinear partial differential equations that govern the propagation dynamics in this case, and subsequently solve them to propose some prototype solutions. These analytical solutions have been obtained;we check the impact of nonlinearity and dispersion. The interest of this work lies not only in the resolution of the partial differential equations that govern the dynamics of wave propagation in this case since these equations not at all easy to integrate analytically and their analytical solutions are very rare, in other words, we propose analytically the solutions of the nonlinear coupled partial differential equations which govern the dynamics of four-wave mixing in optical fibers. Beyond the physical interest of this work, there is also an appreciable mathematical interest.

关键词： Optical Fiber Four Waves Mixing Implicit Bogning Function Coupled Nonlinear Partial Differential Equations Nonlinear Coefficient Dispersive Coefficient Waveguide Properties

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