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A New Method for Diagnosis of Leukemia Utilizing a Hybrid DL-ML Approach for Binary and Multi-Class Classification on a Limited-Sized Database

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Computer Modeling in Engineering & Sciences 2024年第4期139卷 593-631页

作者： nilkanth mukund deshpande Shilpa Gite Biswajeet Pradhan Abdullah Alamri Chang-Wook Lee Department of Electronics&Telecommunication LavaleSymbiosis Institute of TechnologySymbiosis International(Deemed University)PuneMaharashtra412115India Electronics&Telecommunication Dr.Vithalrao Vikhe Patil College of EngineeringAhmednagarMaharashtra414111India Artificial Intelligence and Machine Learning Department Symbiosis Institute of TechnologySymbiosis International(Deemed)UniversityPune412115India Symbiosis Centre of Applied AI(SCAAI) Symbiosis International(Deemed)UniversityPune412115India Centre for AdvancedModelling and Geospatial Information Systems(CAMGIS) School of Civil and Environmental EngineeringFaculty of Engineering&ITUniversity of Technology SydneySydneyAustralia Earth Observation Centre Institute of Climate ChangeUniversiti Kebangsaan MalaysiaBangiSelangor43600Malaysia Department of Geology&Geophysics College of ScienceKing Saud UniversityP.O.Box 2455Riyadh11451Saudi Arabia Department of Science Education Kangwon National UniversityChuncheon-si24341Korea

Infection of leukemia in humans causes many complications in its later *** impairs bone marrow’s ability to produce *** diagnosis of human blood cells is a well-known and well-proven technique for diagnosis in this *** binary classification is employed to distinguish between normal and leukemiainfected *** addition,various subtypes of leukemia require different *** sub-classes must also be detected to obtain an accurate diagnosis of the type of *** entails using multi-class classification to determine the leukemia *** is usually done using a microscopic examination of these blood *** to the requirement of a trained pathologist,the decision process is critical,which leads to the development of an automated software framework for *** utilized state-of-the-art machine learning approaches,such as Support Vector Machine(SVM),Random Forest(RF),Na飗e Bayes,K-Nearest Neighbor(KNN),and others,to provide limited accuracies of *** advanced deep-learning methods are also *** to constrained dataset sizes,these approaches result in over-fitting,reducing their outstanding *** study introduces a deep learning-machine learning combined approach for leukemia *** uses deep transfer learning frameworks to extract and classify features using state-of-the-artmachine learning *** transfer learning frameworks such as VGGNet,Xception,InceptionResV2,Densenet,and ResNet are employed as feature *** extracted features are given to RF and XGBoost classifiers for the binary and multi-class classification of leukemia *** the experimentation,a very popular ALL-IDB dataset is used,approaching a maximum accuracy of 100%.A private real images dataset with three subclasses of leukemia images,including Acute Myloid Leukemia(AML),Chronic Lymphocytic Leukemia(CLL),and Chronic Myloid Leukemia(CML),is also employed to generalize the *** d

关键词： Leukemia diagnosis deep learning machine learning random forest XGBoost

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Explainable Artificial Intelligence-A New Step towards the Trust in Medical Diagnosis with AI Frameworks:A Review

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Computer Modeling in Engineering & Sciences 2022年第12期133卷 843-872页

作者： nilkanth mukund deshpande Shilpa Gite Biswajeet Pradhan Mazen Ebraheem Assiri Department of Electronics&Telecommunication LavaleSymbiosis Institute of TechnologySymbiosis International(Deemed University)Pune412115India Electronics&Telecommunication Vilad GhatDr.Vithalrao Vikhe Patil College of EngineeringAhmednagarMaharashtra414111India Centre for AdvancedModelling and Geospatial Information Systems(CAMGIS) School of Civil and Environmental EngineeringFaculty of Engineering&ITUniversity of Technology SydneySydney2007Australia Center of Excellence for Climate Change Research King Abdulaziz UniversityJeddah21589Saudi Arabia Earth Observation Centre Universiti KebangsaanInstitute of Climate ChangeMalaysiaSelangor43600Malaysia Department of Computer Science LavaleSymbiosis Institute of TechnologySymbiosis International(Deemed University)Pune412115India Symbiosis Center for Applied Artificial Intelligence(SCAAI) LavaleSymbiosis International(Deemed University)Pune412115India

Machine learning(ML)has emerged as a critical enabling tool in the sciences and industry in recent ***’s machine learning algorithms can achieve outstanding performance on an expanding variety of complex tasks-thanks to advancements in technique,the availability of enormous databases,and improved computing *** learning models are at the forefront of this ***,because of their nested nonlinear structure,these strong models are termed as“black boxes,”as they provide no information about how they arrive at their *** a lack of transparencies may be unacceptable in many applications,such as the medical domain.A lot of emphasis has recently been paid to the development of methods for visualizing,explaining,and interpreting deep *** situation is substantially different in safety-critical *** lack of transparency of machine learning techniques may be limiting or even disqualifying issue in this ***,when single bad decisions can endanger human life and health(e.g.,autonomous driving,medical domain)or result in significant monetary losses(e.g.,algorithmic trading),depending on an unintelligible data-driven system may not be an *** lack of transparency is one reason why machine learning in sectors like health is more cautious than in the consumer,e-commerce,or entertainment *** is the term introduced in the preceding *** AImodel’s black box nature will become explainable with these *** in the medical domain,diagnosing a particular disease through AI techniques would be less adapted for commercial *** models’explainable natures will help them commercially in diagnosis decisions in the medical *** paper explores the different frameworks for the explainability of AI models in the medical *** available frameworks are compared with other parameters,and their suitability for medical fields is also discussed.

关键词： Medical imaging explainability artificial intelligence XAI

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