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Recent advances in essential oils and their nanoformulations for poultry feed

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Journal of Animal Science and Biotechnology 2024年第5期15卷 1802-1819页

作者： Fatemeh Movahedi nilesh nirmal Pengyuan Wang Hongping Jin Lisbeth Grondahl Li Li Australian Institute for Bioengineering and Nanotechnology The University of QueenslandBrisbaneQLD 4072Australia Institute of Nutrition Mahidol University999 Phutthamonthon 4 RoadSalayaNakhon Pathom 73170Thailand Oujiang Laboratory Key Laboratory of Alzheimer’s Disease of Zhejiang ProvinceInstitute of AgingWenzhou Medical UniversityWenzhou 325000ZhejiangChina JECHO Biopharmaceuticals Co. Ltd.No.2633Zhongbin AvenueSino‑Singapore Tianjin Eco‑cityBinhai New AreaTianjinChina School of Chemistry and Molecular Biosciences The University of QueenslandBrisbaneQLD 4072Australia

Antibiotics in poultry feed to boost growth performance are becoming increasingly contentious due to concerns over antimicrobial resistance *** oils(EOs),as natural,plant-derived compounds,have demonstrated antimicrobial and antioxidant *** may potentially improve poultry health and growth performance when included in poultry ***,the incorporation of EOs as nutritional additives is hindered by their high volatility,low water solubility,poor intestinal absorption,and sensitivity to environmental ***,nanoencapsulation strategies using nanoformulations have emerged as a potential solution to these challenges,improving the stability and bioavailability of EOs,and enabling targeted delivery in poultry *** review provides an overview of the antioxidant and antibacterial properties of EOs,the current limitations of their applications in poultry feed,and the recent advancements in nano-engineering to overcome these ***,we outline the potential future research direction on EO nanoformulations,emphasizing their promising role in advancing sustainable poultry nutrition.

关键词： Antibacterial activities Antioxidants Essential oils Nanoformulations Poultry additives

Impact of geomorphometric parameters on the occurrence and distribution of landslides in Yamuna River Basin,North-Western Himalaya,India

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Journal of Mountain Science 2022年第8期19卷 2374-2396页

作者： Ravi SHANKAR Gyan prakash SATYAM prakash Kumar SINGH nilesh Kumar RAI Ranjit Kumar PASWAN REED CSIR-Central Institute of Mining and Fuel ResearchDhanbad 826001India Department of Applied Geology Indian Institute of Technology(ISM)Dhanbad 826004India Department of Earth and Planetary Sciences University of AllahabadPrayagraj 211002Uttar PradeshIndia

The majority of landslides in the Indian Himalayas are triggered by rainfall and *** geology and geomorphology also play an important role and constitute the major predisposing factor controlling ***,active tectonics modify the landscape,impacting the occurrence and distribution of *** objective of this study is to investigate the role of some of the major predisposing factors to assess landslide patterns in the Yamuna River Basin as it is prone to recurrent landslide *** approach mainly deals with the application of geographical information system-based statistical analysis and quantifying frequency-area distribution of rainfalltriggered landslides for the years 2015 to *** analysis shows that the frequency of landslides is highest in the slope range 40°-70°and the mean landslide size is higher in the slope range 0°-20°and 30°-40°,remaining constant on further increase in slope *** study shows that some critical slope range controls both the frequency and size of *** were mostly restricted to south facing *** 91%of the landslide occur in the drainage density range of 1.2 to 2.1 km/km^(2) while landslides show very low occurrence in either lower(2.1)drainage *** distribution analysis of landslides depicts a distinct cutoff point but an indistinct rollover ***-sampling of small landslides can be a reasonable cause for *** other studies,the present data fits very well for medium and large landslides following an inverse power law with a scaling exponent *** 80% of landslides are smaller than the cutoff size and 20% larger than this *** geology and tectonics of Lesser Himalayas and Sivaliks offer favorable conditions for frequent *** such as Dehradun,Uttarkashi,Sirmaur,Shimla,and Solan are very prone to landslide activity owing to the presence of poorly consolidated sandstone,conglomerate,quartzites,phylli

关键词： Himalaya Geomorphometry Landslide Yamuna River Basin

Brazilin from Caesalpinia sappan heartwood and its pharmacological activities:A review

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Asian Pacific Journal of Tropical Medicine 2015年第6期8卷 421-430页

作者： nilesh P nirmal Mithun S Rajput Rangabhatla G.S.V.Prasad Mehraj Ahmad Center for Nutrition and Food Sciences Queensland Alliance for Agriculture and Food InnovationUniversity of QueenslandHealth and Food Sciences PrecinctBlock 1039 Kessels RoadCoopers PlainsAcheifield Brisbane QLD 4108Australia Department of Medical Biochemistry.MGM Medical College Biomedical and Pharmaceutical Technology Research Group Nano Research for Advanced Materials Institute of Nutrition.Mahidol University 999 Phutthamonthon 4 Rd.SalayaNakhon Pathom-73170Thailand

Caesalpinia sappan L.(CS) is a plant of Leguminosae family,commonly known as Brazil or Sappan *** is distributed in Southeast Asia and its dried heartwood has been used as traditional ingredient of food or beverages and has a wide variety of medicinal *** extraction yield of CS wood was achieved with 95% ethanol for 2 *** constituent's investigation of sappan wood resulled in the isolation of various structural types of phenolic components including one xanihone,one coumarin,three chalcones,two flavones three homoisoflavonoids and ***[(6a S-cis)-7,11b-dihydrobcnz[b]indeno[1.2-d]pyran-3.6a.9.10(6H)- tetroll.a major and active compound found in CS *** of the folkloric uses of brazilin were validated by the scientific studies such as antioxidant,antibacterial,anti-inflammatory,***,vasorelaxant,hepatoproteetive and anti-acne *** heartwood extract is safe and did not produce any acute or subacute toxicity in both male and female *** is the safe natural compound having potential to develop as a medicinal compound with application in food,beverage,cosmetics and pharmaceutical industries to screen its clinical use in modern *** information gained could provide the important and potential approach for pharmaceutical researcher to implicate the knowledge of brazilin in the formulation of new drug and to reveal therapeutic and gaps requiring future research *** studies are needed to evaluate the potential application of brazilin as preservative and coloring agent in food processing industries.

关键词： Brazilin Caesalpinia sappan Extraction Heartwood Pharamcological activities

Comprehensive Overview of Multi-agent Systems for Controlling Smart Grids

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CSEE Journal of Power and Energy Systems 2022年第1期8卷 115-131页

作者： Om prakash Mahela Mahdi Khosravy Neeraj Gupta Baseem Khan Hassan Haes Alhelou Rajendra Mahla nilesh Patel Pierluigi Siano Power System Planning Division Rajasthan Rajya Vidyut Prasaran Nigam Ltd.Jaipur-302005India Media Integrated Communication Laboratory Graduate School of EngineeringOsaka UniversityOsakaJapan Computer Science and Engineering Department Oakland UniversityRochesterUSA Department of Electrical and Computer Engineering Hawassa UniversityHawassa 1530Ethiopia Faculty of Mechanical and Electrical Engineering Tishreen UniversityLattakiaSyria Department of Electrical Engineering National Institute of Technology Kurukshetra Department of Management&Innovation Systems University of Salerno84084 SalernoItaly

Agents are intelligent entities that act flexibly and autonomously and make wise decisions based on their intelligence and experience.A multi-agent system(MAS)contains multiple,intelligent,and interconnected collaborating agents for solving a problem beyond the ability of a single agent.A smart grid(SG)combines advanced intelligent systems,control techniques,and sensing methods with an existing utility power *** controlling smart grids,various control systems with different architectures have already been ***-based control of power system operations has been shown to overcome the limitations of time required for analysis,relaying,and protection;transmission switching;communication protocols;and management of plant *** systems provide an alternative for fast and accurate power network *** paper provides a comprehensive overview of MASs used for the control of smart *** paper provides a wide-spectrum view of the status of smart grids,MAS-based control techniques and their implementation for the control of smart *** of MASs in the control of various aspects of smart grids-including the management of energy,marketing energy,pricing,scheduling energy,reliability,network security,fault handling capability,communication between agents,SG-electrical vehicles,SG-building energy systems,and soft grids—have been critically *** than a hundred publications on the topic of MAS-based control of smart grids have been critically examined,classified,and arranged for fast reference.

关键词： Coordinated control multi-agent systems renewable energy sources smart energy infrastructure smart grid

Right Radical Nephrectomy with Type-IV IVC Tumor Thrombectomy Using Venovenous Bypass Instead of Cardiopulmonary Bypass—A Case Report

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Open Journal of Urology 2022年第12期12卷 589-595页

作者： Rajiv Kumar Sethia Aakib Hamid Charag Sidhu Sudeep Singh nilesh nirmal Agarwal Pankaj Ingole Department of Urology and Kidney Transplant Asian Institute of Medical Sciences Faridabad Haryana India Department of Cardiac Surgeon Metro Hospital Faridabad Haryana India Department of Cardiac Anasthesia Metro Hospital Faridabad Haryana India

A renal mass with level Level IV IVC thrombus is usually managed with radical nephrectomy and IVC thrombectomy. This procedure requires the assistance of a cardiac surgeon and is usually done under complete cardiopulmonary bypass. However, the use of cardiopulmonary bypass is associated with reduced cardiac venous return and can consequently decrease cardiac output, adversely affecting haemo-dynamic stability and systemic arterial perfusion. This can lead to relative ischemia of the abdominal viscera, lower limbs and kidneys. We report a case where radical nephrectomy with IVC thrombectomy was done under venovenous bypass, thus avoiding the complications associated with the cardiopulmonary bypass.

关键词： Nephrectomy IVC Thrombus Cardiopulmonary Bypass Venovenous Bypass

A Prospective, Multicentric, Post Marketing Surveillance to Evaluate Efficacy & Safety of Ranitidine HCl (150 & 300 mg IR/CR) in Indian Patients with Gastroesophageal Reflux Disease (PROGRADE)

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Open Journal of Gastroenterology 2023年第7期13卷 237-249页

作者： Akash Shukla Anil Kumar Awasthi Ramesh Rao Dawesh prakash Yadav nilesh Nolkha Rajesh Pendlimari Sanjiv Dua Shrish Bhatnagar Ravindra Mote Ashish Birla Jay Savai Kapil Mehta Shashank Salunke Department of Gastroenterology Gastro Universe Mumbai India Department of Medicine Ajanta Research Centre Ajanta Hospital & IVF Centre Lucknow India Departmentof Nephrology Sanjeevani Kidney Care Mumbai India Department of Gastroenterology Institute of Medical Sciences Banaras Hindu University Varanasi India Department of Rheumatology Wockhardt Hospitals Mumbai India Department of Gastroenterology Rajalakshmi Hospital and Research Center Bangalore India Department of General Surgery SaiKripa Hospital Mumbai India Department of Gastroenterology Sparsh Child Care and Gastro Centre Lucknow India Department of Clinical Research Mediclin Clinical Research Mumbai India Department of Medical Affairs JB Chemicals & Pharmaceuticals Ltd. Mumbai India

Purpose: Ranitidine hydrochloride (HCl) remains an important medication for treating acid-peptic ailments such as Gastroesophageal reflux disease (GERD). The main objective of this Post Marketing Surveillance (PMS) clinical study was to test the efficacy and safety of Ranitidine HCl in Indian patients suffering from GERD. Patients and Methods: Data of 2446 patients (1307 males;1121 females) from 21 centers across India were analyzed. Patients received either of the three treatments: Ranitidine HCl 150 mg twice a day (BID) (ARM-A), Ranitidine HCl 300 mg once daily (OD) or BID (ARM-B), and Ranitidine HCl 300 mg OD (ARM-C). Gastroesophageal Reflux Disease Symptom Assessment Scale (GSAS) score and Heartburn Severity score were used to assess the drug’s efficacy. The adverse events reported by patients or investigators were analyzed to assess the safety profile of Ranitidine. Results: Of the 2446 subjects screened, 2428 were enrolled. There was a significant reduction in GSAS scores from baseline to the end of the study visit in all three ARMs. The GSAS scores reduced from 2.02 to 0.23 in ARM-A, 2.01 to 0.24 in ARM-B, and 2.07 to 0.26 in ARM-C patients. In ARM A, 72.82% had 24 hours heartburn-free days, and 66.89% had 7 consecutive heartburn-free days, which was more significant than the other two ARMs. 128 (5.27%) patients reported ADRs due to Ranitidine HCl at different doses. The most frequently reported ADR was constipation (17.18%), followed by oliguria (14.06%), cold (13.28%), and dysuria (12.5%). Of 128 ADRs, 113 (88.28%) were mild, and only 11 (8.59%) ADRs were related to the study drug. No severe ADRs were reported during the study. Conclusion: Ranitidine HCl 150/300 mg tablet was found to be an effective and safe H2-receptor antagonist for treating GERD in Indian Patients.

关键词： Ranitidine Hydrochloride GERD Heartburn H2-Receptor Antagonists

Life Cycle Energy of Low Rise Residential Buildings in Indian Context

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Open Journal of Energy Efficiency 2014年第4期3卷 108-118页

作者： Talakonukula Ramesh Ravi prakash Karunesh Kumar Shukla Government Polytechnic Nirmal India Department of Mechanical Engineering Motilal Nehru National Institute of Technology Allahabad India Department of Applied Mechanics Motilal Nehru National Institute of Technology Allahabad India

Life cycle energy of the building accounts for all energy inputs to the buildings during their intended service life. Buildings need to be constructed in such a way that energy consumption in their life cycle is minimal. Life Cycle Energy (LCE) consumption data of buildings is not available in public domain which is essentially required for building designers and policy makers to formulate strategies for reduction in LCE of buildings. The paper presents LCE of twenty (20) low rise residential buildings in Indian context. LCE of the studied buildings is varying from 160 - 380 kWh/m2 year (Primary). Based on the LCE data of studied buildings, an equation is proposed to readily reckon LCE of a new building.

关键词： Life Cycle Energy Residential Buildings Embodied Energy Operating Energy

A Prospective, Multicentric, Post Marketing Surveillance to Evaluate Efficacy & Safety of Ranitidine HCl (150 & 300 mg IR/CR) in Indian Patients with Gastroesophageal Reflux Disease (PROGRADE)

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