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Prevalence of Bicuspid Aortic Valve in Turner Syndrome Patients Receiving Cardiac MRI and CT: A Meta-Analysis

Congenital Heart Disease 2022年第2期17卷 129-140页

作者： Pengzhu Li Martina Bacova Robert Dalla-Pozza nikolaus alexander haas Felix Sebastian Oberhoffer Department of Pediatric Cardiology and Intensive Care Medical Hospital of the University of MunichLudwig Maximilians University MunichMunichGermany

Turner syndrome(TS)is a rare disorder affecting 25–50 in 100000 female *** aortic valve(BAV)is assumed to be the most common congenital heart defect(CHD)in *** literature,reported BAV prevalence in TS ranges between 14%and 34%.The specific BAV prevalence in TS is still *** aim of this study was to give a more precise estimation of BAV prevalence in TS by conducting a meta-analysis of TS-studies,which detected BAV by either cardiac magnetic resonance imaging(MRI)or cardiac computed tomography(CT).We searched PubMed,Cochrane Library,and Web of Science databases to collect observational studies including the prevalence of BAV identified by cardiac MRI or cardiac CT in TS patients up to June 4th,*** screening for inclusion,data extraction,and quality assessment by two independent reviewers,the meta-analysis was performed with R 4.1.1 *** are shown as proportion and weighted mean difference with 95%confidence intervals(95%CI).In total,11 studies involving 1177 patients were *** data showed that the prevalence of BAV in TS patients was 23.7%(95%CI:21.3%to 26.1%).No high heterogeneity was found between the included *** current meta-analysis reveals that BAVcan be detected in 23.7%of TS patients receiving cardiac MRI or cardiac ***,BAV can be considered as the most common CHD in *** to TTE,cardiac MRI and cardiac CT might represent superior imaging modalities in BAV assessment of adult TS patients.

关键词： Turner syndrome bicuspid aortic valve magnetic resonance imaging(MRI) tomography X-ray computed(CT)

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