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The Impact of a Prior Norwood Procedure on Cardiac Transplantation in Failed Fontan Physiology

Congenital Heart Disease 2024年第3期19卷 257-266页

作者： Ryan G.mcQueen nikki m.singh Ronald K.Woods medical College of Wisconsin Herma Heart Institute at Children’s WisconsinMilwaukeeUSA Division of Pediatric Cardiology Medical College of WisconsinHerma Heart Institute at Children’s WisconsinMilwaukeeUSA Division of Pediatric Cardiothoracic Surgery Medical College of WisconsinHerma Heart Institute at Children’s WisconsinMilwaukeeUSA

Objective:The objective of this study was to compare cardiac transplant operative and postoperative courses of patients with failed Fontan physiology who were initially palliated with a Norwood(FFN)to those without a prior Norwood(FF).methods:A single-institution retrospective review of all patients with Fontan failure who under-went cardiac transplantation from 2003–2021 was completed-22 underwent prior Norwood(FFN)and 11 did not(FF).Descriptive and inferential statistics were calculated for operative course and patient ***:The operative course of the FFN cohort appeared to be more complex(not statistically signiﬁcant,but clinically relevant)-this group exclusively experienced sternal re-entry events(3 of 22 patients)and concomitant neo-aor-tic reconstruction(6 patients),had a longer duration of surgery(median of 682 min vs.575.5 min),more time on circulatory arrest(median of 25.5 min vs.12.5 min),and more frequent use of open sternal management[50%of patients(11/22)vs.27.3%of patients(3/11)].Postoperatively,these patients underwent more mediastinal explora-tions[other than sternal closure;40.9%of patients(9/22)vs.18.2%of patients(2/11)],spent more time on mechanical ventilation(median of 5 days vs.2 days),had a longer length of stay(median of 30 days vs.19 days),and required more catheter-based re-interventions[22.7%of patients(5/22)vs.9.1%of patients(1/11)].Conclu-sion:Although underpowered,our results suggest that the operative course of FFN patients is more challenging,based mostly on neo-aortic arch *** turn,this likely leads to a more complex postoperative *** are currently collaborating with other institutions to increase the cohort size and power of the study.

关键词： Fontan Fontan failure Norwood cardiac transplantation

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Laser-induced graphene-coated wearable smart textile electrodes for biopotentials signal monitoring

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Frontiers of materials Science 2024年第1期18卷 95-111页

作者： C.m.Vidhya Yogita maithani Sakshi Kapoor J.P.singh Department of Physics Indian Institute of Technology DelhiHauz KhasNew Delhi 110016India

This paper describes how to produce a wearable dry electrode at a reasonable cost and how to use it for the monitoring of biopotentials in *** textiles in wearable technologies have made a great advancement in the health care management and living standards of *** was manufactured using the low-cost single-step process,laser ablation of polyimide,a commercial *** dispersions were made using solvent isopropyl alcohol which has low boiling point,nontoxicity,and environmental *** successive coating of the graphene dispersion on the cotton fabric to make it conductive,the sheet resistance of the resulting fabric dropped to 3% of its initial *** laser-induced graphene(LIG)cotton dry electrodes thus manufactured are comparable to Ag/AgCl wet electrodes in terms of the skin-to-electrode impedance,measuring between 78.0 and 7.2 kΩ for the frequency between 40 Hz and 1 *** LIG cotton electrode displayed a signal-to-noise ratio of 20.17 *** to its comfort,simplicity,and good performance over a longer period of time,the textile electrode appears suited for medical applications.

关键词： biopotential electrocardiogram electromyogram flexible electrode textile porous graphene

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Application of Response Surface methodology for Analysing and Optimizing the Finned Solar Air Heater

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Journal of Thermal Science 2024年第3期33卷 985-1009页

作者： Vineet singh Vinod singh YADAV Vaibhav TRIVEDI manoj KUmAR Niraj KUmAR Department of mechanical Engineering School of Engineering&TechnologyIFTM UniversityMoradabadUttar PradeshIndia Department of mechanical Engineering NITUttarakhandPauriUttarakhandIndia Department of Electronics and Communication Engineering Jaypee Institute of Information TechnologyNoidaUttar Pradesh201309India

In this research paper,a solar air heater with triangular fins has been experimentally analysed and ***,an experimental set-up of a solar air heater having triangular fins has been developed at the location of 28.10°N,78.23°*** heat transfer rate through fins and fins efficiency has been determined by the Finite Difference method model *** experimental data and modeled data of response parameters have been optimized in mINITAB-17 software by the Response Surface methodology *** creating the response surface design,three input parameters have been selected namely solar intensity,Reynolds number,and fin base-to-height *** range of solar intensity,Reynolds number,and fin base-to-height ratio is 600 to 1000W/m^(2),4000 to 6000,and 0.4 to 0.8 *** response surface design has been analyzed by calculating the outlet temperature,friction factor,Nusselt number,fin efficiency,thermal performance factor,and exergy *** optimum settings of input parameters:solar intensity is 1000 W/m^(2);Reynolds number is 4969.7,and the fin base to height ratio is 0.6060,on which these response:namely outlet temperature of 92.531℃,friction factor of 0.2350,Nusselt number of 127.761,thermal efficiency of 50.836%,thermal performance factor of 1.4947,and exergy efficiency of 8.762%.

关键词： solar air heater optimization fins exergy response surface methodology air

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Investigating the Evolution of Amati Parameters with Redshift

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Research in Astronomy and Astrophysics 2024年第1期24卷 188-200页

作者： meghendra singh Darshan singh Kanhaiya Lal Pandey Dinkar Verma Shashikant Gupta Delhi metro Rail Corporation Limited New Delhi 110001India GD Goenka University Gurugram 122103India Department of Physics Mata Raj Kaur Institute of Engineering and TechnologyRewari 123401India Department of Physics School of Advanced SciencesVellore Institute of TechnologyVellore 632014India

Gamma-ray bursts(GRBs) are among the brightest objects in the Universe and, hence, can be observed up to a very high redshift. Properly calibrated empirical correlations between intensity and spectral correlations of GRBs can be used to estimate the cosmological parameters. However, the possibility of the evolution of GRBs with redshift is a long-standing puzzle. In this work, we used 162 long-duration GRBs to determine whether GRBs below and above a certain redshift have different properties. The GRBs are split into two groups, and we fit the Amati relation for each group separately. Our findings demonstrate that estimations of the Amati parameters for the two groups are substantially dissimilar. We perform simulations to investigate whether the selection effects could cause the difference. Our analysis shows that the differences may be either intrinsic or due to systematic errors in the data, and the selection effects are not their true origin. However, in-depth analysis with a new data set comprised of 119 long GRBs shows that intrinsic scatter may partly be responsible for such effects.

关键词： Cosmology gamma rays:general (cosmology:)large-scale structure of universe galaxies:high-redshift

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magnesium oxide(mgO)nanoadsorbents in wastewater treatment:A comprehensive review

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Journal of magnesium and Alloys 2024年第5期12卷 1709-1773页

作者： H.C.S.Perera V.Gurunanthanan Anoop singh m.m.m.G.P.G.mantilaka G.Das Sandeep Arya Department of Physics Khalifa UniversityAbu Dhabi12788United Arab Emirates Postgraduate Institute of Science University of PeradeniyaPeradeniyaSri Lanka Department of Humanities and Sciences Guru Nanak Institutions Technical CampusIbrahimpatnamHyderabad501506India Centre for Global Health Research Saveetha Medical College and HospitalsSaveetha Institute of Medical and Technical SciencesChennai602105Tamil NaduIndia Department of Physics University of JammuJammu and Kashmir180006India

Wastewater contamination by heavy metals and synthetic dyes presents a significant environmental challenge,necessitating effective and sustainable separation *** review article provides a detailed examination of magnesium oxide(mgO)nanoparticles as an innovative nanoadsorbent for wastewater treatment,with a specific focus on heavy metal and dye *** review comprehensively explores various aspects of mgO nanoparticles,including their structural characteristics and synthesis *** article delves into the morphology and crystallographic arrangement of mgO nanoparticles,offering insights into their structural *** the complexity of adsorption processes,the review identifies and analyzes parameters influencing the adsorption efficiency of mgO nanoparticles,such as temperature,pH,contact time,initial concentration,and co-existing *** interplay between these parameters and the adsorption capability of mgO nanoparticles emphasizes the importance of optimizing operational ***,the review assesses various synthesis methods for mgO nanoparticles,including sol-gel,hydrothermal,precipitation,green synthesis,solvothermal,and template-assisted *** discusses the advantages,limitations,and resulting nanoparticle characteristics of each method,enabling readers to grasp the implications of synthesis processes on adsorption *** comprehensive review consolidates current insights into the effectiveness of mgO nanoparticles as a potent nanoadsorbent for removing heavy metals and dyes from wastewater covering a wide spectrum of aspects related to mgO ***,there is a need to investigate the use of mgO in the treatment of actual wastewater or river water,in order to leverage its cost-effectiveness and high efficiency for practical water treatment applications in real-time.

关键词： mgO nanoparticles Nanoadsorbent Wastewater treatment Heavy metals Dye separation Adsorption Synthesis methods

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Constructing a biofunctionalized 3D-printed gelatin/sodium alginate/chitosan tri-polymer complex scaffold with improvised biological andmechanical properties for bone-tissue engineering

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Bio-Design and manufacturing 2024年第1期7卷 57-73页

作者： Amit Kumar singh Krishna Pramanik Amit Biswas Centre of Excellence in Tissue Engineering Department of Biotechnology and Medical EngineeringNational Institute of TechnologyRourkela 769008India

Sodium alginate(SA)/chitosan(CH)polyelectrolyte scaffold is a suitable substrate for tissue-engineering *** present study deals with further improvement in the tensile strength and biological properties of this type of scaffold to make it a potential template for bone-tissue *** experimented with adding 0%–15%(volume fraction)gelatin(GE),a protein-based biopolymer known to promote cell adhesion,proliferation,and *** resulting tri-polymer complex was used as bioink to fabricate SA/CH/GEmatrices by three-dimensional(3D)*** studies using scanning electron microscopy revealed the microfibrous porous architecture of all the structures,which had a pore size range of 383–419μm.X-ray diffraction and Fourier-transform infrared spectroscopy analyses revealed the amorphous nature of the scaffold and the strong electrostatic interactions among the functional groups of the polymers,thereby forming polyelectrolyte complexes which were found to improve mechanical properties and structural *** scaffolds exhibited a desirable degradation rate,controlled swelling,and hydrophilic characteristics which are favorable for bone-tissue *** tensile strength improved from(386±15)to(693±15)kPa due to the increased stiffness of SA/CH scaffolds upon addition of *** enhanced protein adsorption and in vitro bioactivity(forming an apatite layer)confirmed the ability of the SA/CH/GE scaffold to offer higher cellular adhesion and a bone-like environment to cells during the process of tissue *** vitro biological evaluation including the mTT assay,confocal microscopy analysis,and alizarin red S assay showed a significant increase in cell attachment,cell viability,and cell proliferation,which further improved biomineralization over the scaffold *** addition,SA/CH containing 15%gelatin designated as SA/CH/GE15 showed superior performance to the other fabricated 3D structures,demonstrating its pote

关键词： Scaffold Biomaterial Sodium alginate Chitosan Gelatin 3D printing Tissue engineering

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Influence of cerium ions on structure-dependent magnetic properties of Ba-Sr m-type hexaferrite nanocrystals

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Journal of Rare Earths 2024年第2期42卷 364-372,I0005页

作者： Ram A.Pawar Sunil m.Patange P.m.Dighe Sher singh meena Abdullah GAl-Sehemi mehboobali Pannipara Santosh S.Jadhav Department of Physics ArtsCommerce and Science CollegeAhmednagar413711MaharashtraIndia Department of Physics Shri Krishna MahavidyalayaGunjotiDistOsmanabad413606MaharashtraIndia Padmashri Vikhe Patil College of Arts Science and CommercePravaranagarA/P.Loni(Kd)Tal.RahataDistAhmednagar413713MaharashtraIndia Solid State Physics Division Bhabha Atomic Research CentreMumbai400085MaharashtraIndia Department of Chemistry King Khalid UniversityAbha61413Saudi Arabia Department of Physics D.S.M's ArtsCommerce and Science CollegeJintur431509MaharashtraIndia

The present study is a systematic effort to investigate the structure-sensitive magnetic parameters of Ce^(3+) substituted Ba-Sr hexaferrite nanocrystals chemically formulated as Ba_(0.5)Sr_(0.5)Ce_(x)Fe_(12-x)O_(19) where x=0.0-0.2 with Δx=*** hexaferrite powders were prepared using the sol-gel self-ignition route and structurally characterized by means of powder X-ray diffraction and Fourier transform infrared *** creation of the m-type hexaferrite phase within the synthesized samples was revealed from the Rietveld refinement of the X-ray *** occurrence of a secondary phase of CeO_(2) was revealed within the hexaferrites for the substitution,x> *** refined X-ray diffraction data were utilized to compute the lattice parameters,X-ray density,and lattice parameter *** crystal structure plotted from the refined XRD data reveals the occupancy of the ions at different lattice *** XPS data of the hexaferrite were analyzed to confirm the oxidation states of the constituent *** nanocrystalline nature of the hexaferrites was revealed from the crystallite sizes calculated using Scherer's *** analysis of FTIR spectra confirms that only a fraction of Ce^(3+)accommodated in the lattice and the remaining Ce content reside in the form of the CeO_(2) *** morphology of the hexaferrites was analyzed from the FESEm profiles of the ferrite *** magnetic behavior study was performed by analyzing the Curie temperature,hysteresis loops,and hyperfine interactions by means of susceptibility,V.S.m,and mossbauer spectroscopy,*** hexaferrites with increasing coercivity,decreasing saturation magnetization,and decreasing Curie temperature are reported in the *** substituted Ce^(3+)ions inhibit the grain growth and create lattice imperfections giving rise to hexaferrites with tuned magnetic parameters suitable for different applications.

关键词： Ba-Sr hexaferrite Ce^(3+)substitution XPS Saturation magnetization Coercivity m?ssbauer spectroscopy

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Coumarin and eugenol ameliorate LPS-induced inflammation in RAW 264.7 cells via modulating the NLRP3 inflammasome pathway

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Asian Pacific Journal of Tropical Biomedicine 2024年第1期14卷 40-46页

作者： Jyotsana Bakshi Somnath singh KP mishra DRDO Defence Institute of Physiology and Allied Sciences DelhiIndia

Objective:To investigate the underlying mechanism of anti-inflammatory action of coumarin and eugenol in lipopolysaccharide(LPS)-stimulated RAW 264.7 ***:RAW 264.7 cells were treated with 2.5μg/mL of LPS,50μm of coumarin,and 50μm eugenol for 24 *** viability of the cells was assessed using mTT *** production of nitric oxide was determined using Griess reagent and DCFH-DA was used to measure the production of reactive oxygen *** protein expression of NLRP3,IL-1β,NF-κB,and cyclooxygenase 2 was assessed using Western blot ***:Coumarin and eugenol showed anti-inflammatory effects against LPS-induced inflammatory response by ameliorating the expression of NLRP3 inflammasome and NF-κB,which further led to a subsequent reduction in IL-1β,nitric oxide,and reactive oxygen ***:Coumarin and eugenol exert their anti-inflammatory activities by modulating the NLRP3 inflammasome pathway and NF-κ*** compounds may have promising therapeutic applications for the treatment of various inflammatory diseases.

关键词： Inflammation Cytokines Coumarin Eugenol NLRP3 LPS

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Incense smoke(IS)inhalation exposure system:Physicochemical characterization,IS particle deposition and clearance in human airway using mPPD model

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Particuology 2024年第4期87卷 271-285页

作者： Vyas Kumar Hafsa Hashmi Anshita Nasreen Ghazi Ansari Jyotsna singh Inhalation Toxicology Facility Regulatory Toxicology GroupCSR-Indian Institute of Toxicology ResearchLucknow22001UPIndi Academy of Scientific and Innovative Research(AcsSIR) Ghaziabad201002UPIndia Analytical Chemistry Regulatory Toxicology GroupCSIR-Indian Institute of Toxicology ResearchLucknow226001UPIndia

Incense smoke(IS)is source of indoor air pollution and key risk for diverse human *** in-formation is available regarding controlled IS rodent inhalation exposure system and IS particulate matter(Pm)deposition in human *** aimed to demonstrate stable ISPm physicochemical parameters of 10 incense products inside the customized whole body inhalation exposure chamber(without animal)connected to smoke generation unit via aerosol mixing *** analyzed for size segregated Pm emission,ISPm in vitro aerodynamics(mmAD and GSD determination),fine and ultrafine particle's SEm,SEm-EDX and PAH *** real life exposure scenario by utilizing mmAD,GSD and Pm concentration after Tier 1 exposure assessment as key input parameters,ISPm dosimetry in infant(3 months)and adult(21 years male and female)human airways was calculated using multiple-path particle dosimetry(mPPD 3.04)*** median aerodynamic diameter(mmAD)and geo-metric standard deviation(GSD)ranged between 0.55 and 2.10μm and 1.22 to 1.77(polydisperse)***1.0 and Pm0.1 showed multiple morphology and presence of heavy and trace *** like acenaphthylene,anthracene,fluorene,naphthalene and phenanthrene were detected(0.84-143.17μg/g).mPPD results showed higher ISPm deposition in pulmonary region and lowest in trachea bronchial *** deposition in tissue was higher in lower,peripheral lung as compared to upper and central lung *** body inhalation exposure system showed stable IS atmosphere(physi-cochemical parameters)indicating the device suitability in future inhalation *** ISPm deposition fraction and clearance data showed deep lung penetrating and retention behavior with higher risk in infant followed by female and then *** modeled particle deposition and clearance data may be useful in risk assessment analysis of IS.

关键词： Inhalation Incense smoke multiple-path particle dosimetry(mPPD) Particle deposition Particulate matter(Pm) mass median aerodynamic diameter (mmAD) Human airway

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Biorenewable materials for water remediation: The central role of cellulose in achieving sustainability

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Journal of Bioresources and Bioproducts 2024年第3期9卷 253-282页

作者： Kirti mishra Samarjeet singh Siwal Thandiwe Sithole Nirankar singh Phil Hart Vijay Kumar Thakur Department of Chemistry M.M.Engineering CollegeMaharishi Markandeshwar(Deemed to be University)Haryana 133207India Department of Chemical Engineering University of JohannesburgDoornfontein 2088South Africa Biorefining and Advanced materials Research Center Scotland’s Rural CollegeEdinburgh EH93JGUnited Kingdom Renewable and Sustainable Energy Research Centre Technology Innovation InstituteAbu Dhabi 9639United Arab Emirates School of Engineering University of Petroleum&Energy StudiesDehradun 248007India

As the population increases and manufacturing grows,greenhouse gas and other harmful emissions *** with chemicals such as dyes,pesticides,pharmaceuticals,oil,heavy metals or radionuclides,wastewater purification has become an urgent *** technologies exist that can remove these contaminants from wastewater sources,but they often demand high energy and/or high cost,and in some cases produce contaminant laden sludge that requires safe *** need for methods which are less capital intensive,less operationally costly and more environmentally friendly is ***-based materials have emerged as promising candidates for wastewater treatment due to their renewability,low cost,biodegradability,hydrophilicity,and antimicrobial *** this review article,we focussed on developing sustainable and biodegradable cellulose-based materials for wastewater *** article deals with cellulose-based materials’scope and their conversion into valuable products like hydrogel,aerogel,cellulose composites,and *** cellulose-based materials have no harmful environmental impact and are *** modified cellulose-based materials applying as membrane,adsorbent,sorbent,and beads to purify the wastewater were ***,the challenges and future prospects of cellulose-based materials for wastewater treatment were considered,emphasizing their potential to be sustainable and eco-friendly alternatives to traditional materials used in wastewater treatment.

关键词： Cellulose Wastewater treatment Hydrogel Nanocrystal Cellulose membrane

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