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Probiotics viability in frozen food products

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Food Bioscience 2022年第6期50卷 1193-1203页

作者： nikita Tyutkov Anastasia Zhernyakova Artyom Birchenko Elmira Eminova Liudmila Nadtochii Denis Baranenko International Research Centre “Biotechnologies of the Third Millennium” Faculty of Biotechnologies (BioTech)ITMO UniversitySaint-PetersburgLomonosova str.9191002Russia

Improving gastrointestinal flora with probiotics is a promising method of treating and preventing many ***,in food industry,introduction of probiotics is limited by the shelf life of products,as well as by the reduction of bacterial viability during ***,introduction of probiotics into foods to be frozen is a promising method to extend the shelf life of probiotic ***,the storage of living cells in frozen products involves their damage during freezing and subsequent storage at temperatures below 0°***,some technological solutions are required to protect probiotics during storage at ***,encapsulation,addition of cryoprotectants and prebiotics,as well as adaptation of microorganisms are widely used techniques of protecting *** combination of various protection methods is a promising way to improve the viability of probiotics during *** aimed at investigating various combinations of hurdle methods and their effect on bacterial survival are of great *** review compiles the most common methods of preserving probiotics in frozen foods,describing their effects,variety of approaches,and *** main mechanisms of bacterial cell damage by freezing are *** trends in probiotic protection in frozen foods are also discussed.

关键词： Probiotic Frozen food Probiotic viability Encapsulation Cryoprotectant

Robust State Estimation for an Electricity-Gas-Heat Integrated Energy System Considering Dynamic Characteristics

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Protection and Control of Modern Power Systems 2024年第1期9卷 65-80页

作者： Jianshu Yu Dechang Yang Jinye Cao Payman Dehghanian nikita Tomin 不详 College of Information and Electrical Engineering China Agricultural UniversityBeijing 100084China China Agricultural University

The data for an energy management system(EMS)in an integrated energy system(IES)is obtained through state *** is then the basis for optimal scheduling,protection and *** present,the dynamic models of gas and heat networks are rarely considered in such state estimation,and the method lacks *** paper develops dynamic state estimation models for gas and heat networks,and proposes a unified method for the electricity-gas-heat network,one which takes into account robustness while ensuring ***,the state transition equations in matrix form are formulated according to finite difference models consid-ering the dynamic characteristics of the gas and heat ***,combined with a quasi-steady state model of the electric power system,a unified state estimation method and multi-time-scale measurement strategy in the Kalman filter framework are *** addition,the prediction accuracies of the electric power and gas systems are improved through adaptive *** kernel density estimation method is used to adjust the measurement weights and filter out bad data to ensure robust state ***,simulation results show that the proposed method not only can improve the estimation accuracy by improving prediction accuracy,but also is robust to various types of bad data.

关键词： estimation prediction unified

Calcium Carbide:From Elemental Carbon to Isotope-Economic Synthesis of^(13)C_(2)-Labeled Heterocycles

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Chinese Journal of Chemistry 2023年第21期41卷 2810-2818页

作者： Maria S.Ledovskaya Vladimir V.Voronin nikita R.Valov Dmitriy E.Samoylenko Saint Petersburg State University Institute of ChemistryUniversitetsky prospect 26Peterhof198504 Russia

^(13)C-Carbon is the most available source of *** is a relatively inexpensive solid material,which can be easily converted to calcium carbide-^(13)C_(2).In current work,Ca^(13)C_(2)was used for in situ generation of^(13)C_(2)-acetylene in 1,3-dipolar cycloaddition and[4+2]cycloaddition *** the first time,1H-1,2,3-triazoles-4,5-^(13)C_(2)and isoxazoles-4,5-^(13)C_(2)were synthesized using calcium carbide-^(13)C_(2).A Diels-Alder type cycloaddition of 3,6-di(pyridin-2-yl)-1,2,4,5-tetrazine and Ca^(13)C_(2)was investigated,and the best way for the synthesis of 3,6-di(pyridin-2-yl)pyridazine-4,5-^(13)C_(2)was proposed for the first *** we perform a detailled description of NMR spectra of^(13)C_(2)-labeled triazoles,isoxazoles and 3,6-di(pyridin-2-yl)pyridazine.

关键词： Isotopic labeling Cycloaddition Click chemistry Sustainable Chemistry Calcium carbide

Effect of WC/Ni-Cr additive on changes in the composition of an atmospheric residue in the course of cracking

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Petroleum Science 2020年第2期17卷 499-508页

作者： Galina S.Pevneva Natalya G.Voronetskaya nikita N.Sviridenko Anatoly K.Golovko Institute of Petroleum Chemistry SB RAS 4 Akademicheskiy AveTomskRussia 634055

The paper presents the results of investigation of changes in the composition of hydrocarbons and sulfur-containing compounds of an atmospheric residue in the course of cracking in the presence of a tungsten carbide-nickel-chromium(WC/Ni-Cr)catalytic additive and without *** cracking is carried out in an autoclave at 500℃for 30 *** addition of the WC/Ni-Cr additive promotes the deepening of reactions of destruction not only of resins and asphaltenes,but also high molecular weight naphthene-aromatic compounds of the atmospheric *** is shown that the content of low molecular weight C9-C17 n-alkanes and C9-C10 alkylbenzenes rose sharply in the products of cracking with addition of WC/Ni-Cr in comparison with those produced without the ***-and naphthene-substituted aromatic hydrocarbons of benzene,naphthalene,phenanthrene series,polyarenes,benzo-and dibenzothiophenes are identified.

关键词： Atmospheric residue Cracking Catalytic additive Hydrocarbons Composition

Electrically programmable solid-state metasurfaces via flash localised heating

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Light(Science & Applications) 2023年第3期12卷 391-397页

作者： Khosro Zangeneh Kamali Lei Xu nikita Gagrani Hark Hoe Tan Chennupati Jagadish Andrey Miroshnichenko Dragomir Neshev Mohsen Rahmani ARC Centre of Excellence for Transformative Meta-Optical Systems(TMOS) Research School of PhysicsThe Australian National UniversityCanberraACT 2601Australia Advanced Optics and Photonics Laboratory Department of EngineeringSchool of Science and TechnologyNottingham Trent UniversityNottinghamNG118NSUK School of Engineering and Information Technology University of New South WalesCanberraACT 2600Australia

In the last decades,metasurfaces have attracted much attention because of their extraordinary light-scattering ***,their inherently static geometry is an obstacle to many applications where dynamic tunability in their optical behaviour is ***,there is a quest to enable dynamic tuning of metasurface properties,particularly with fast tuning rate,large modulation by small electrical signals,solid state and programmable across multiple ***,we demonstrate electrically tunable metasurfaces driven by thermo-optic effect and flash-heating in *** show a 9-fold change in transmission by<5 V biasing voltage and the modulation rise-time of<625µ*** device consists of a silicon hole array metasurface encapsulated by transparent conducting oxide as a localised *** allows for video frame rate optical switching over multiple pixels that can be electrically *** of the advantages of the proposed tuning method compared with other methods are the possibility to apply it for modulation in the visible and near-infrared region,large modulation depth,working at transmission regime,exhibiting low optical loss,low input voltage requirement,and operating with higher than video-rate switching *** device is furthermore compatible with modern electronic display technologies and could be ideal for personal electronic devices such as flat displays,virtual reality holography and light detection and ranging,where fast,solid-state and transparent optical switches are required.

关键词： tuning flash state

Assessment of the ecological state of haplic chernozem contaminated by oil,fuel oil and gasoline after remediation

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Petroleum Research 2024年第1期9卷 155-164页

作者： Anna Ruseva Tatiana Minnikova Sergey Kolesnikov Dmitry Trufanov nikita Minin Sofya Revina Vladimir Gayvoronsky Southern Federal University Academy of Biology and Biotechnology344090Rostov-on-DonRussia

The intensive use of petroleum hydrocarbon products has made them priority environmental *** petroleum hydrocarbons enter the soil,a change in physical,chemical,and biological properties is *** natural restoration of oil-contaminated soils is a lengthy process;therefore,remediation is often *** aim of this study is to assess the change in the ecological state of haplic chernozem soil contaminated with oil,fuel oil,and gasoline after *** indicators of soil biological activity,such as phytotoxicity(germination,length of shoots and roots),the activity of oxidoreductase enzymes(catalase and dehydrogenases),and the total number of bacteria were *** effects of nitroammophoska fertilizer,sodium humate,biochar,and the biofertilizer“Baikal EM-1”on the ecological state of soils contaminated with oil,fuel oil,and gasoline were *** with oil,fuel oil,and gasoline decreased the values of all biological *** most sensitive indicator was the length of radish roots in soils polluted with oil,gasoline,and fuel oil after remediation with nitroammophoska and Baikal EM-1 *** length of roots was the most sensitive indicator when remediation was performed with biochar and sodium humate added to soil contaminated with oil and gasoline,and with contamination of haplic chernozem soil with fuel oil,the total number of bacteria was the most sensitive *** most effective ameliorant to phytotoxicity indicators for oil pollution was a 1 D dose of biochar,for fuel oil it was 1 D biochar and 2 D sodium humate,and for gasoline it was a 2 D dose of biochar and Baikal *** ameliorants at most of the studied doses increased dehydrogenase activity,but increased catalase activity only in some *** increase in the total number of bacteria in oil-contaminated soils was promoted by biochar and nitroammophoska at a dose of 2 *** was the most effective in ameliorant in soils contaminated with fuel

关键词： Pollution Petroleum hydrocarbons Haplic chernozem Ameliorant dose Biological indicators Soil properties

In vivo solid phase microextraction for therapeutic monitoring and pharmacometabolomic fingerprinting of lung during in vivo lung perfusion of FOLFOX

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Journal of Pharmaceutical Analysis 2023年第10期13卷 1195-1204页

作者： nikita Looby Anna Roszkowska Miao Yu German Rios-Gomez Mauricio Pipkin Barbara Bojko Marcelo Cypel Janusz Pawliszyn Department of Chemistry University of Waterloo200 University Avenue WestWaterlooONN2L 3G1Canada Department of Pharmaceutical Chemistry Medical University of Gdansk80-416GdanskPoland Division of Thoracic Surgery University Health NetworkTGH200 Elizabeth StTorontoONM5G 2C4Canada Department of Pharmacodynamics and Molecular Pharmacology Collegium Medicum in BydgoszczNicolaus Copernicus University in Torun85-089BydgoszczPoland

In vivo lung perfusion(IVLP)is a novel isolated lung technique developed to enable the local,in situ administration of high-dose chemotherapy to treat metastatic lung *** therapy using folinic acid(FOL),5-fluorouracil(F),and oxaliplatin(OX)(FOLFOX)is routinely employed to treat several types of solid tumours in various ***,F is characterized by large interpatient variability with respect to plasma concentration,which necessitates close monitoring during treatments using of this *** plasma drug concentrations often do not reflect tissue drug concentrations,it is essential to utilize sample-preparation methods specifically suited to monitoring drug levels in target *** this work,in vivo solid-phase microextraction(in vivo SPME)is proposed as an effective tool for quantitative therapeutic drug monitoring of FOLFOX in porcine lungs during pre-clinical IVLP and intravenous(IV)*** concomitant extraction of other endogenous and exogenous small molecules from the lung and their detection via liquid chromatography coupled to high resolution mass spectrometry(LC-HRMS)enabled an assessment of FOLFOX's impact on the metabolomic profile of the lung and revealed the metabolic pathways associated with the route of administration(IVLP ***)and the therapy *** study also shows that the immediate instrumental analysis of metabolomic samples is ideal,as long-term storage at80℃ results in changes in the metabolite content in the sample extracts.

关键词： In vivo lung perfusion Solid-phase microextraction Chemotherapy Metabolomics Therapeutic drug monitoring

Empirical Assessment of Bacillus Calmette-Guérin Vaccine to Combat COVID-19

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Computers, Materials & Continua 2022年第1期70卷 213-231页

作者： nikita Jain Vedika Gupta Chinmay Chakraborty Agam Madan Deepali Virmani Lorenzo Salas-Morera Laura Garcia-Hernandez Department of Computer Science&Engineering Bharati Vidyapeeth’s College of EngineeringNew Delhi110063India Department of Electronics&Communication Engineering Birla Institute of TechnologyMesra814142India Department of Computer Science&Engineering Bhagwan Parshuram Institute of TechnologyNew Delhi110063India Area of Project Engineering University of CórdobaCórdoba14071Spain

COVID-19 has become one of the critical health issues globally,which surfaced first in latter part of the year *** is the topmost concern for many nations’governments as the contagious virus started mushrooming over adjacent regions of infected *** 1980,a vaccine called Bacillus Calmette-Guérin(BCG)was introduced for preventing tuberculosis and lung *** that have made the BCG vaccine mandatory have witnessed a lesser COVID-19 fatality rate than the countries that have not made it *** paper’s initial research shows that the countries with a longtermcompulsory BCGvaccination system are less affected by COVID-19 than those without a BCG vaccination *** paper discusses analytical data patterns for medical applications regarding COVID-19 impact on countries with mandatory BCG status on fatality *** paper has tackled numerous analytical challenges to realize the full potential of heterogeneous *** analogy is drawn to demonstrate how other factors can affect fatality and infection rates other than BCG vaccination only,such as age groups affected,other diseases,and stringency *** data of Spain,Portugal,and Germany have been taken for a case study of BCG impact analysis.

关键词： Bacillus Calmette-Guérin COVID-19 fatality rate lockdown gross domestic product vaccine

Market capitalization shock effects on open innovation models in e‑commerce:golden cut q‑rung orthopair fuzzy multicriteria decision‑making analysis

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Financial Innovation 2023年第1期9卷 1476-1500页

作者： nikita Moiseev Alexey Mikhaylov Hasan Dinçer Serhat Yüksel Department of Mathematical Methods in Economics Plekhanov Russian University of EconomicsMoscowRussia Financial University Under the Government of the Russian Federation MoscowRussia The School of Business İstanbul Medipol UniversityIstanbulTurkey

This research paper analyzes revenue trends in e-commerce,a sector with an annual sales volume of more than 340 billion *** article evaluates,despite a scarcity of data,the effects on e-commerce development of the ubiquitous lockdowns and restriction measures introduced by most countries during the pandemic *** analysis covers monthly data from January 1996 to February *** research paper analyzes relative changes in the original time series through the autocorrelation *** objects of this analysis are Amazon and Alibaba,as they are benchmarks in the e-commerce *** paper tests the shock effect on the e-commerce companies Alibaba in China and Amazon in the USA,concluding that it is weaker for companies with small market *** a result,the effect on estimated e-trade volume in the USA was approximately 35%in *** evaluation considers fuzzy decision-making *** this purpose,balanced scorecard-based open financial innovation models for the e-commerce industry are weighted with multistepwise weight assessment ratio analysis based on q-rung orthopair fuzzy sets and the golden *** this framework,a detailed analysis of competitors should be *** paper proves that this situation positively affects the development of successful financial innovation models for the e-commerce ***,it may be possible to attract greater attention from e-commerce companies for these financial innovation products.

关键词： E-commerce Golden cut Open innovation Sustainable trade