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Helicobacter pylori infection and respiratory diseases:a review

World Journal of Gastroenterology 2003年第1期9卷 5-8页

作者： Anastasios Roussos nikiforos philippou Konstantinos I Gourgoulianis 9th Department of Pulmonary Medicine "SOTIRIA"Chest Diseases HospitalAthensGreece Pulmonary Department Medical University of ThesallyLarisaGreece

In the past few years,a variety of extradigestive disorders, including cardiovascular,skin,rheumatic and liver diseases, have been associated with Helicobacter pylori(***) *** activation of inflammatory mediators by *** seems to be the pathogenetic mechanism underlying the observed *** present review summarizes the current literature,including our own studies,concerning the association between *** and respiratory diseases. A small number of epidemiological and serologic,case- control studies suggest that *** infection may be associated with the development of chronic bronchitis.A frequent coexistence of pulmonary tuberculosis and *** infection has also been ***,recent studies have shown an increased *** in patients with bronchiectasis and in those with lung *** the other hand,bronchial asthma seems not to be related with *** infection. All associations between *** infection and respiratory diseases are primarily based on case-control studies, concerning relatively small numbers of ***, there is a lack of studies focused on the pathogenetic link between respiratory diseases and *** infection. Therefore,we believe that larger studies should be undertaken to confirm the observed results and to clarify the underlying pathogenetic mechanisms.

关键词： Helicobacter pylori Asthma Bronchiectasis Bronchitis, Chronic Helicobacter Infections Humans Lung Neoplasms Respiratory Tract Diseases Seroepidemiologic Studies Tuberculosis, Pulmonary

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