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Leukemoid reaction in a patient with COVID-19 infection: A case report

Journal of Acute Disease 2022年第3期11卷 120-122页

作者： Prabhat Agrawal Ashish Gautam Anjana Pandey Harendra Kumar nikhil pursnani Departments of Medicine S.N.Medical CollegeAgraIndia Departments of PathologyS.N.Medical CollegeAgraIndia

Rationale:COVID-19 usually presents with flu-like symptoms and signs,but some rare presentations like leukemoid symptoms cannot be ***’s concerns:A 37-year-old female presented to the outpatient department with flu-like ***:The RT-PCR test for SARS-CoV-2 infection was positive,while complete blood cell and peripheral blood smear showed leukemoid ***:Paracetamol and fexofenadine for flu-like symptoms and leukemoid ***:On the 10th day,the patient was asymptomatic and RT-PCR was *** the patient was discharged and leukemoid presentation subsided after clearance of viral ***:COVID-19 has a myriad of presentations,and unusual symptoms/signs especially in this pandemic could be induced by COVID-19 infection.

关键词： COVID-19 Leukemoid reaction Atypical presentation Abnormal total leucocyte count Leukocytosis

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Cardiovascular sequelae in post-COVID-19 patients with moderate to severe CT severity score: A follow-up study

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Journal of Acute Disease 2023年第5期12卷 198-203页

作者： Niharika Agarwal Anamika Goyal nikhil pursnani Garima Kanaujia Akanksha Semwal Prabhat Agrawal Abhishek Raj Department of Medicine S.N.Medical CollegeAgraUttar PradeshIndia Department of Paediatrics S.N.Medical CollegeAgraUttar PradeshIndia

Objective:To study cardiovascular sequelae of post-COVID-19 patients with moderate to severe computed tomography(CT)severity ***:A prospective,non-randomized,observational study was conducted on 100 post-COVID-19 patients with moderate to severe CT severity scores from January 2021 to December ***-nine were male[mean age(54.1±12.2)years]and 41 were female[mean age(46.9±15.1)years].Patients with previous cardiovascular disease,previous chronic lung disease,and pre-existing primary or secondary pulmonary hypertension were *** were examined,and serial electrocardiogram and 2D echocardiography were performed to detect any cardiovascular ***:Post-COVID-19 patients had persistent symptoms,the most common being fatigue(59%).Most of these symptoms were relieved on follow-up.A rise in systolic,diastolic blood pressure,and pulse rate was *** electrocardiographic evaluation revealed ST-T segment changes,sinus tachycardia,ventricular hypertrophy,and arrhythmias among a considerable number of *** echocardiography,left ventricular diastolic dysfunction was most common(43%).Pulmonary hypertension,as evidenced by elevated pulmonary artery systolic pressure,was seen in 15%of ***:The present findings reveal an increased incidence of cardiovascular complications after recovery from COVID-19 infection in those without pre-existing cardiovascular or chronic lung disease.

关键词： Cardiovascular outcomes Arrhythmia Heart failure Post acute-sequale Long COVID-19

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Link between Friesinger Index and Lipid Profile in Patients Undergoing Diagnostic Coronary Angiography

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International Journal of Clinical Medicine 2015年第8期6卷 538-546页

作者： Deepesh Agarwal Ramanand P. Sinha Ram Mohan Jaiswal nikhil pursnani Nirlep Gajiwala Ashok Thakkar Mahatma Gandhi Cardiac and Critical Care Center Jaipur India Sahajanand Medical Technologies Pvt. Ltd. Surat India

Background: A strong association between abnormal lipid variables and development of atherosclerosis is widely established. However, few data exist on the association between lipid levels and the extent or severity of coronary lesions in patients with coronary artery disease. Objective: We aimed to determine the link between lipid levels and the extent or severity of coronary lesions in patients with suspected coronary artery disease using Friesinger index (FR). Methodology: In this prospective and singe-center study, consecutive patients who underwent coronary angiography for diagnostic purposes were analyzed. Each participant was evaluated for lipid levels i.e. total cholesterol, triglycerides, high-density lipoprotein (HDL) cholesterol, low-density lipoprotein (LDL) cholesterol, very-low-density lipoprotein (VLDL) cholesterol, non-HDL cholesterol, triglycerides/ HDL cholesterol, and triglycerides/non-HDL cholesterol. The extent of coronary disease was evaluated using FR index. Results: A total of 566 patients (mean age: 56.17 ± 9.99 years) were included in the study. The mean FR index was 5.40 ± 3.78. A significantly positive correlation was observed between FR index and total cholesterol (P = 0.002), triglycerides (P < 0.001), VLDL cholesterol (P < 0.001), non-HDL cholesterol (P = 0.006), triglycerides/HDL cholesterol ratio (P = 0.008), and triglycerides/non-HDL cholesterol ratio (P = 0.002). On the contrary, an inverse correlation was observed between FR index and HDL cholesterol (P < 0.001). Age or gender played no role in governing the FR index severity, while body-mass index, hypertension, diabetes, and smoking showed significant association with FR index (P < 0.001 for all). Conclusion: The present study demonstrates a significant link between the extent of coronary artery disease and levels of certain lipid variables.

关键词： Cholesterol Coronary Angiography Coronary Artery Disease Friesinger Index Lipid Profile Triglyceride

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