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Laboratory efficacy of mycoparasitic fungi(Aspergillus tubingensis and Trichoderma harzianum) against tropical bed bugs(Cimex hemipterus)(Hemiptera:Cimicidae)

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Asian Pacific Journal of Tropical Biomedicine 2017年第4期7卷 288-293页

作者： Zulaikha Zahran nik mohd izham mohamed nor Hamady Dieng Tomomitsu Satho Abdul Hafiz Ab Majid Household and Structural Urban Entomology Laboratory Vector Control Research UnitSchool of Biological SciencesUniversiti Sains Malaysia Plant Pathology Laboratory School of Biological SciencesUniversiti Sains Malaysia Institute of Biodiversity and Environmental Conservation Universiti Malaysia Sarawak Department of Microbiology Faculty of Pharmaceutical SciencesFukuoka University

Objective: To test the effectiveness of conidial spore formulations [Aspergillus tubingensis(***) and Trichoderma harzianum(***)] against tropical bed bugs, Cimex ***: Spore formulations were made from two fungal strains, *** and *** bed bugs were exposed to the conidial spores placed soaked onto a fabric cloth for 1 h and the mortality counts were recorded daily until 14 ***: Mean survival times based on Kaplan–Meier survival analysis showed no significant differences between all the concentrations in both the fungal isolates:*** and ***, the evaluation of both the isolates in terms of virulence resulted in low lethal hours in all the concentrations except for the high concentration of ***(LT_(50)= 44.629 h) at the conidial exposure of 1 × 10~6 spores/*** mortality of the bed bugs was observed from Day 6 to Day 12, ranging from 13% to 90% in all three concentrations of *** reference to the *** exposure, the concentration of 1 × 10~4 spores/mL displayed a gradual increase in the percentage mortality of 90 on Day ***: Approaches to the bed bugs treatment should be explored in-depth using a natural biological agent like fungus especially *** to reduce this pest population, in order to replace chemical methods.

关键词： Tropical bed bug Mycoparasitic fungi Aspergillus tubingensis Trichoderma harzianum Bio-control

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Markov Chain Modelling of Reliability Analysis and Prediction under Mixed Mode Loading

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Chinese Journal of Mechanical Engineering 2015年第2期28卷 307-314页

作者： SINGH Salvinder ABDULLAH Shahrum nik mohamed nik Abdullah mohd NOORANI mohd Salmi Department of Mechanical and Materials Engineering Faculty of Engineering & Built EnvironmentUniversiti Kebangsaan Malaysia Department of Mechanical Engineering Universiti Malaysia Pahang School of Mathematical Sciences Faculty of Science and TechnologyUniversiti Kebangsaan Malaysia

The reliability assessment for an automobile crankshaft provides an important understanding in dealing with the design life of the component in order to eliminate or reduce the likelihood of failure and safety *** failures of the crankshafts are considered as a catastrophic failure that leads towards a severe failure of the engine block and its other connecting *** reliability of an automotive crankshaft under mixed mode loading using the Markov Chain Model is *** Markov Chain is modelled by using a two-state condition to represent the bending and torsion loads that would occur on the *** automotive crankshaft represents a good case study of a component under mixed mode loading due to the rotating bending and torsion *** estimation of the Weibull shape parameter is used to obtain the probability density function,cumulative distribution function,hazard and reliability rate functions,the bathtub curve and the mean time to *** various properties of the shape parameter is used to model the failure characteristic through the bathtub curve is ***,an understanding of the patterns posed by the hazard rate onto the component can be used to improve the design and increase the life cycle based on the reliability and dependability of the *** proposed reliability assessment provides an accurate,efficient,fast and cost effective reliability analysis in contrast to costly and lengthy experimental techniques.

关键词： reliability Weibull Markov Chain mixed mode failure

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Numerical and experimental investigation of three-dimensionality in the dam-break flow against a vertical wall

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Journal of Hydrodynamics 2018年第4期30卷 682-693页

作者： mohamed M.Kamra nik mohd Cheng Liu Makoto Sueyoshi Changhong Hu Interdisciplinary Graduate School of Engineering Seieneesl Kyushu University Kasuga Fukuoka Japan Research Institute for Applied Mechanics Kyushu University Kasuga Fukuoka Japan

The three-dimensionality extent of the dam break flow over a vertical wall is investigated numerically and experimentally in this paper. The numerical method is based on Reynolds averaged Navier-Stokes（RANS） equation that describes the three-dimensional incompressible turbulent flow. The free surface is captured by using the unstructured multi-dimensional interface capturing（UMTHINC） scheme. The equations are discretized on 2-D and 3-D unstructured grids using finite volume method. The numerical simulations are compared with newly conducted experiment with emphasis on the effect of three-dimensionality on both free surface and impact pressure. The comparison between the numerical and experimental results shows good agreement. Furthermore, the results also show that 3-D motion of the flow originates at the moment of impact at the lower corners of the impact wall and propagates to the inner region as time advances. The origin of the three-dimensionality is found to be the turbulence development as well as the relative velocity between the side wall region and the inner region of the wave front at the moment of impact.

关键词： Water impact dam break flow UMTHINC scheme three-dimensionality

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Antibiotic resistance and molecular typing of clinical Staphylococcus aureus isolates from Malaysian military hospital

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Asian Pacific Journal of Tropical Medicine 2023年第5期16卷 220-231页

作者： nor Syaza Syahirah Amat Junaidi nik Noorul Shakira mohamed Shakrin Mohammad Fahmi Daman Huri Ahmad Zakwan Kamarudin mohd Nasir mohd Desa Wan mohd Zin Wan Yunus Faculty of Medicine and Defence Health Universiti Pertahanan Nasional Malaysia(UPNM)Kem Sungai Besi57000 Sungai BesiKuala LumpurMalaysia Centre for Tropicalization(CENTROP) Universiti Pertahanan Nasional Malaysia(UPNM)Kem Sungai Besi57000 Sungai BesiKuala LumpurMalaysia Pathology Department Tuanku Mizan Armed Forces Hospital(TMAFH)53300 Kuala LumpurMalaysia Faculty of Medicine and Health Sciences Universiti Sains Islam Malaysia(USIM)Persiaran IlmuPutra Nilai71800 NilaiNegeri SembilanMalaysia Department of Biomedical Science Faculty of Medicine and Health SciencesUniversiti Putra Malaysia43400 SerdangSelangorMalaysia Faculty of Defence Science and Technology Universiti Pertahanan Nasional Malaysia(UPNM)Kem Sungai Besi57000 Sungai BesiKuala LumpurMalaysia

Objective:To determine the antibiotic resistance profile(ARP)of Staphylococcus(S.)aureus isolates and molecular typing of the methicillin-resistant ***(MRSA)isolates from Tuanku Mizan Armed Forces Hospital(TMAFH),Kuala ***:The ARP and presence of the pvl gene were determined for 209 *** isolates from clinical *** these,123 were methicillin-susceptible ***(MSSA)isolates and 86 were MRSA *** MRSA isolates were characterized using SCCmec typing and spa *** analysis was performed to compare the demographic data with the phenotypic and genotypic variables of the *** ***:No vancomycin-intermediate and-resistant ***(VISA and VRSA,respectively)were detected among the study *** MSSA isolates showed low resistance rates to all tested antibiotics,were commonly invasive(28/42,66.7%),and mostly harboured pvl(35/42,83.3%).Meanwhile,MRSA isolates showed high resistance to penicillin(86/86,100%),ampicillin(86/86,100%),sulbactam/ampicillin(86/86,100%),cefuroxime(81/86,94.19%),cefoperazone(76/86,88.37%),azithromycin(56/86,65.12%),and erythromycin(54/86,62.79%).The majority of MRSA isolates were of SCCmec type IVh(65/86,75.58%),spa type t032(55/85,63.95%),and grouped into spaCC-t022(66/85,77.65%).The t032 type was found to be associated with resistance traits to azithromycin and erythromycin(P<0.05).We also found several spa types that are typically associated with hospital-,community-,and livestock-associated MRSA co-existing in our MRSA ***:This study reflected the consistent absence of VISA and VRSA and corroborated the clonal shifting of MRSA isolates in the Malaysian MRSA isolates.

关键词： Staphylococcus aureus Methicillin-resistant Staphylococcus aureus spa typing SCCmec typing Antibiotic resistance

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The protective effects of procyanidin C-1 on bisphenol A-induced testicular dysfunction in aged mice

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Food Science and Human Wellness 2022年第4期11卷 965-974页

作者： Mastura Abd Malek Razif Dasiman nor-Ashikin mohamed Noor Khan Sofee mohamed-Akhlak mohd-Hafi zi Mahmud Maternofetal and Embryo Research Group(MatE) Faculty of MedicineUniversiti Teknologi MARASelangor BranchSungai Buloh Campus47000 Sungai BulohSelangorMalaysia Faculty of Health Sciences Universiti Teknologi MARASelangor BranchPuncak Alam Campus42300 Puncak AlamSelangorMalaysia

The number and quality of sperm are decreased due to bisphenol A(BPA) exposure, an endocrine-disrupting chemical on the male reproductive system, especially in advanced paternal age(APA). Procyanidin C-1(PCY-1), an antioxidant from grape seed(Vitis vinifera L.), has demonstrated anti-viral, anti-melanogenic and immunostimulatory effects. Therefore, this study aims to determine the effects of PCY-1 intervention on sperm parameters, testis morphological changes, serum testosterone, oestradiol, and luteinizing hormone(LH) concentrations and the expression of apoptotic(Bax and Bcl-2) and mitochondria-related(Mfn1 and Opa1) genes in BPA-exposed aged mice. Results revealed that PCY-1 intervention improves aged male fertility in BPA-exposed conditions by decreasing abnormal sperms percentage and increasing spermatogenic cell diameter and epithelial height. PCY-1 also decreased oestradiol, and increased LH and testosterone levels. The gene expression of Bax was significantly down-regulated by PCY-1 intervention. In contrast, Bcl-2 was substantially up-regulated. Expression of Mfn1 and Opa1 genes were also significantly up-regulated in the PCY intervention group. Hence, it is demonstrated that PCY-1 was able to mitigate the adverse effects of BPA on reproductive parameters of aged mice. Collectively, we postulated that PCY-1 has a potential role in protecting the ageing male reproductive system against the damaging impacts of BPA.

关键词： Apoptosis Bisphenol A Procyanidin Mitochondrial dynamics Testis

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Influence of urban air pollution on the population in the Klang Valley,Malaysia:a spatial approach

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Ecological Processes 2022年第1期11卷 126-141页

作者： Siti Haslina mohd Shafie Mastura Mahmud Suzani Mohamad nor Lita Fadilah Rameli Ramdzani Abdullah Ahmad Fariz mohamed Centre for Research in Development Social and Environment(SEEDS)Faculty of Social Sciences and HumanitiesUniversiti Kebangsaan MalaysiaBangiSelangorMalaysia Department of Environment Faculty of Forestry and Envi-ronmentUniversiti Putra MalaysiaSerdangSelangorMalaysia Institute for Environment and Development(LESTARI) Universiti Kebangsaan MalaysiaBangiSelangorMalaysia.

Background:Urban air pollution resulting from economic growth as well as urbanization impacts the health of *** study aims to examine the spatial distribution of particulate matter(PM_(10))and the risk of exposure for the population in the Klang Valley,an urban conglomeration centred in Kuala Lumpur,***:The inverse distance weighted(IDW)interpolation technique in the ArcGIS platform was used to map the air quality from five air monitoring *** statistics of the Global Moran’s I Spatial Autocorrelation and Optimized Hot Spot Analysis were used to estimate the spatial clustering of PM_(10).The population-weighted exposure level(PWEL)technique was used to calculate the population density susceptible to PM_(10)and the AirQ+model was applied to estimate the proportion of the adult population at risk of chronic bronchitis due to long-term exposure to PM_(10)concentrations in the Klang ***:The highest annual mean PM_(10)concentrations at the Klang station ranged between 80 and 100μg/m^(3)from 2000 to 2009 and exceeded the New Malaysia Ambient Air Quality Standard(NMAAQS)and the World Health Organi-zation Air Quality Guidelines(WHOAQG)levels of 40 and 20μg/m^(3),*** Moran’s I results indicated that the statistically significant clusters of high PM_(10)in Klang present a health risk to the local *** PWEL results showed that levels of PM_(10)in Petaling Jaya exceeded the WHOAQG limits,potentially posing a health risk to the high-density *** AirQ+model found Klang to be a significantly high-risk area for chronic bronchitis among the adult population with 804,240 people(with a relative risk of 1.85)in ***:These high-risk values are due to rapid urbanization and high motor vehicle usage in the Klang Valley and therefore the impact of PM_(10)on the population needs to be *** situation should be taken seriously by the Department of Environment and Kuala Lumpur City Hall in addre

关键词： Population Urban air pollution Spatial distribution PM_(10) Adult chronic bronchitis risk

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Effects of dietary astaxanthin enrichment on enhancing the colour and growth of red tilapia,Oreochromis sp.

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Aquaculture and Fisheries 2024年第1期9卷 52-56页

作者： Zuharlida Tuan Harith Suniza mohd Sukri nor Fatin Syuhada Remlee Fatin Nursabriena mohd Sabir nik Nur Azwanida Zakaria Faculty of Agro Based Industry Universiti Malaysia Kelantan Jeli CampusJeliKelantan17600Malaysia

The aim of this research was to examine the effects of dietary inclusion of astaxanthin from Haematococcus pluvialis in commercial fish feed on the colour and growth of red tilapia,Oreochromis sp..A 6-week feeding trial was conducted at concentration of astaxanthin at 0%(T1),4%(T2),8%(T3)and 12%(T4)in feed formulation to examine the growth performance,colour pigmentation on skin,texture analysis and carotenoid *** showed an increment of certain growth parameter in fish fed with astaxanthin enriched *** in weight gain(WG),protein efficiency ratio(PER)was obtained in fish fed with astaxanthin enriched compared with *** treatments with astaxanthin-enriched provided higher redness(a*)to skin than negative control that directly influence the colour of the *** can be concluded that inclusion of astaxanthin from green algae into commercial fish feed can be used as an alternative natural carotenoid source in Oreochromis *** to ensure good pigmentation,hence improving the skin colour for more appealing and subsequently increase the market value of the fish.

关键词： Oreochromis sp. Astaxanthin Haematococcus pluvialis

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Demethylbelamcandaquinone B from Marantodes pumilum ***(Blume)Kuntze inhibits osteoclast differentiation in RAW264.7 cells

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Asian Pacific Journal of Tropical Biomedicine 2021年第12期11卷 535-542页

作者： Haryati Ahmad Hairi Jamia Azdina Jamal nor Ashila Aladdin Khairana Husain Noor Suhaili mohd Sofi norazlina mohamed Isa Naina mohamed Ahmad Nazrun Shuid Department of Biochemistry Faculty of MedicineManipal University College MalaysiaJalan Batu HamparBukit Baru75150 MelakaMalaysia Faculty of Pharmacy Universiti Kebangsaan MalaysiaJalan Raja Muda Abdul Aziz50300 Kuala LumpurMalaysia Department of Pharmacology Faculty of MedicinePreclinical BuildingUniversiti Kebangsaan MalaysiaJalan Yaacob LatiffBandar Tun RazakCheras56000 Kuala LumpurMalaysia Department of Pharmacology Faculty of MedicineUniversiti Teknologi MaraJalan Hospital47000 Sungai BulohSelangorMalaysia

Objective:To investigate the bone-resorbing effect of demethylbelamcandaquinone B(Dmcq B)extracted from Marantodes pumilum *** on osteoclast differentiation in RAW264.7 ***:RAW264.7 macrophages were differentiated using RANKL into osteoclast-like ***,they were treated with 10μg/mL Marantodes pumilum *** crude aqueous extract,5μg/mL dichloromethane fraction,and 0.6μg/mL Dmcq B and 0.06μg/mL ***-resistant acid phosphatase 5b(TRACP 5b)as an osteoclast phenotypic marker was determined by TRACP staining and TRACP 5b colometric assay,and bone-resorbing pits were *** gene expression of pro-inflammatory cytokines(TNF-αand IL-6)was ***,the protein expressions of pro-inflammatory cytokines(TNF-αand IL-6)and estrogen receptors were ***:Marantodes pumilum *** crude aqueous extract and Dmcq B inhibited RANKL-stimulated osteoclast differentiation as evidenced by size reduction of giant multinucleated osteoclast cells,decreased TRACP 5b activity as well as the subsiding of resorbed pit area compared with normal *** addition,they reduced the gene and protein expressions of TNF-αand *** pumilum ***,Dmcq B,and estradiol treatments increased the protein expressions of estrogen receptors alpha and beta in ***:Marantodes pumilum *** and its active compound,Dmcq B can inhibit osteoclast differentiation.

关键词： Marantodes pumilum var.alata Phytoestrogen RAW264.7 induced-osteoclast Bone-resorbing effect

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Phytochemical constituents,antioxidant and antibacterial activities of methanolic extract of Ardisia elliptica

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Asian Pacific Journal of Tropical Biomedicine 2017年第6期7卷 569-576页

作者： Nazeh M.Al-Abd Zurainee mohamed nor Marzida Mansor Asdren Zajmi mohd Shahnaz Hasan Fadzly Azhar Mustafa Kassim Department of Parasitology Faculty of MedicineUniversity of Malaya Faculty of Medicine and Health Sciences University of Aden Department of Anesthesiology Faculty of MedicineUniversity of Malaya Department of Diagnostic and Allied Health Sciences Faculty of Health and Life SciencesManagement and Science University Department of Chemistry Faculty of ScienceUniversity of Malaya

Objective:To investigate the antioxidant,antibacterial,and chemical ingredients of Ardisia elliptica(***) methanolic ***:The plant was extracted using *** and antioxidant activities were ***:The results showed that both fruit and leaf extract of *** have significant antibacterial activities against Gram-positive and Gram-negative *** extracts showed higher content of phenolic(71 ± 0.03 GAE/mg extract dry weight),in comparison to the leaf extracts(37 ± 0.05 GAE/mg extract dry weight).Flavonoid content,and Fe2+chelating activity of fruit extracts were higher than leaf *** percentage radical inhibition of fruit extract is found to be higher(70%) than that of leaf extract(60%).LCMS results indicated that the major compounds in the fruit extract were Gingerol,Aspidin,Kampherol,and Stercuresin,while the leaf extract contained Gingerol,Aspidin,Triangularin,and Salicyl acyl ***,the results of GCMS indicated that fruit extract contained these major compounds:Vitamin E Tocopherol,5-hepylresornicol,2-Nonylmalonic acid,5-pentadecylresornicol,and ***,leaf extract of *** contained these major compounds:Alpha Amyrenol,4,4,6,6a,6b,8,8a,9,10,11,12,12 a,14,14 a,14 b octadehydro-2H-picen-3-one,and Lonasterol,4-t-Butyl-2-[4-nitrophenyl] ***:The results provide evidence that fruit and leaf of *** extracts might indeed be used as a potential source of effective natural antimicrobial and antioxidant agents in pharmaceutical and food industries.

关键词： Ardisia elliptica Antioxidant capacity Total phenol content Gas chromatography/mass spectrometry Liquid chromatography/mass spectrometry

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The Effects of Stacking Sequence on Dynamic Mechanical Properties and Thermal Degradation of Kenaf/Jute Hybrid Composites

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Journal of Renewable Materials 2021年第1期9卷 73-84页

作者： Tabrej Khan mohamed Thariq Hameed Sultan Mohammad Jawaid Syafiqah Nur Azrie Safri Ain Umaira Md Shah mohd Shukry Abdul Majid nik noriman Zulkepli Haliza Jaya Department of Aerospace Engineering Faculty of EngineeringUniversiti Putra MalaysiaSerdang43400Malaysia Laboratory of Biocomposite Technology Institute of Tropical Forestry and Forest ProductsUniversiti Putra MalaysiaSerdang43400Malaysia Aerospace Malaysia Innovation Centre Prime Minister’s DepartmentMIGHT Partnership HubCyberjaya63000Malaysia School of Mechatronic Engineering Universiti Malaysia PerlisPauh Putra CampusArau02600Malaysia School of Manufacturing Engineering Universiti Malaysia PerlisPauh Putra CampusArau02600Malaysia Center of Excellence Geopolymer and Green Technology Faculty of Engineering TechnologyUniversiti Malaysia PerlisArau02600Malaysia

This research focused on the dynamic mechanical and thermal properties of woven mat jute/kenaf/jute(J/K/J)and kenaf/jute/kenaf(K/J/K)hybrid *** mechanical analysis(DMA)and Thermo-gravimetric Analysis(TGA)were used to study the effect of layering sequence on the thermal properties of kenaf/jute hybrid *** DMA results;it was found that the differences in the stacking sequence between the kenaf/jute composites do not affect their storage modulus,loss modulus and damping *** the TGA and DMA results,it has been shown that stacking sequence has given positive effect to the kenaf/jute hybrid composite compared to pure epoxy *** is because kenaf and jute fibre has increased the Tg values of the composites,thus affect the thermal *** showed that the storage modulus for kenaf/jute hybrid composites increased compared with pure epoxy composites with increasing temperature and the values of remained almost the same at glass transition temperature(Tg),the hybrid composite perhaps due to the improved fibre/matrix interface *** preliminary analysis could provide a new direction for the creation of a novel hybrid composite which offers unique properties which cannot be accomplished in a single material system.

关键词： Hybrid composites dynamic mechanical thermal analysis(DMTA) thermo-gravimetric analysis

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