检索结果-南通市图书馆

Uncovering the genetic diversity of Giardia intestinalis in isolates from outbreaks in New Zealand

Infectious Diseases of poverty 2022年第3期11卷 27-36页

作者： paul Ogbuigwe patrick J.Biggs Juan Carlos Garcia-Ramirez Matthew A.Knox Anthony pita Niluka Velathanthiri nigel p.french David T.S.Hayman School of Veterinary Science Massey UniversityPalmerston NorthManawatu-WanganuiNew Zealand School of Natural Sciences Massey UniversityPalmerston NorthManawatu-WanganuiNew Zealand

Background:Giardia intestinalis is one of the most common causes of diarrhoea worldwide. Molecular techniques have greatly improved our understanding of the taxonomy and epidemiology of this parasite. Co-infection with mixed (sub-) assemblages has been reported, however, Sanger sequencing is sometimes unable to identify shared subtypes between samples involved in the same epidemiologically linked event, due to samples showing multiple dominant subtypes within the same outbreak. Here, we aimed to use a metabarcoding approach to uncover the genetic diversity within samples from sporadic and outbreak cases of giardiasis to characterise the subtype diversity, and determine if there are common sequences shared by epidemiologically linked cases that are missed by Sanger ***:We built a database with 1109 unique glutamate dehydrogenase (gdh) locus sequences covering most of the assemblages of G. intestinalis and used gdh metabarcoding to analyse 16 samples from sporadic and outbreak cases of giardiasis that occurred in New Zealand between 2010 and ***:There is considerable diversity of subtypes of G. intestinalis present in each sample. The utilisation of metabarcoding enabled the identification of shared subtypes between samples from the same outbreak. Multiple variants were identified in 13 of 16 samples, with Assemblage B variants most common, and Assemblages E and A present in mixed ***:This study showed that G. intestinalis infections in humans are frequently mixed, with multiple subtypes present in each host. Shared sequences among epidemiologically linked cases not identified through Sanger sequencing were detected. Considering the variation in symptoms observed in cases of giardiasis, and the potential link between symptoms and (sub-) assemblages, the frequency of mixed infections could have implications for our understanding of host–pathogen interactions.

关键词： DNA sequencing Epidemiology Genetic diversity Giardiasis Metabarcoding

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

纳博恩博物馆

引用

世界建筑导报 2021年第2期36卷 40-42页

作者： nigel Young(摄影) philippe Chancel(摄影) 福斯特建筑事务所不详

纳博恩市曾是一个古罗马的重要港口,一直以来不断有人于此安家落户,累积了不少令人过目难忘的建筑、古代遗迹与考古遗址遗产。该作品为福斯特建筑事务所与博物馆专家阿德里安•卡迪(Adrien Gardère)的工作室联合设计,以博物馆的主要展... 详细信息

纳博恩市曾是一个古罗马的重要港口,一直以来不断有人于此安家落户,累积了不少令人过目难忘的建筑、古代遗迹与考古遗址遗产。该作品为福斯特建筑事务所与博物馆专家阿德里安•卡迪(Adrien Gardère)的工作室联合设计,以博物馆的主要展品为基础,即1000多块从19世纪的城市中世纪城墙上复原的古代葬礼石器收藏。上述藏品的展示传达了建筑的结构风格,简单的直线结构中心处,一道天然屏障得以形成,将公共展区与修复空间隔开,且有组织的团体可以进入该空间参观。参观者可以透过石雕和灯光的交相呼应,一睹考古学家与研究人员的工作成果,同时灵活的展示框架易于浮雕的再次排列,不失为一个难得的学习工具。博物馆为单层结构,行政办公室位于夹层。

关键词：建筑事务所天然屏障交相呼应单层结构考古遗址博物馆直线结构阿德里安

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Laser produced electromagnetic pulses: generation, detection and mitigation

引用

High power Laser Science and Engineering 2020年第2期8卷 88-146页

作者： Fabrizio Consoli Vladimir TTikhonchuk Matthieu Bardon philip Bradford David CCarroll Jakub Cikhardt Mattia Cipriani Robert JClarke Thomas ECowan Colin NDanson Riccardo De Angelis Massimo De Marco Jean-Luc Dubois Bertr Etchessahar Alejro Laso Garcia David IHillier Ales Honsa Weiman Jiang Viliam Kmetik Josef Krása Yutong Li FredériéLubrano paul McKenna Josefine Metzkes-Ng Alexre poyé Irene prencipe piotr Ra¸czka Rol ASmith Roman Vrana nigel CWoolsey Egle Zemaityte Yihang Zhang Zhe Zhang Bernhard Zielbauer David Neely ENEA Fusion and Technologies for Nuclear Safety DepartmentC.R.Frascati00044 FrascatiItaly CELIA University of BordeauxCNRSCEA33405 TalenceFrance ELI Beamlines Institute of PhysicsCzech Academy of Sciences25241 Dolni BrezanyCzech Republic CEA DAMCESTA33116 Le BarpFrance Department of physics York Plasma InstituteUniversity of YorkHeslingtonYork YO105DDUK Central Laser Facility Rutherford Appleton LaboratorySTFCUKRIChiltonDidcotOxfordshire OX110QXUK Czech Technical University in prague Faculty of Electrical Engineering16627 Prague 6Czech Republic Institute of plasma physics of the Czech Academy of Sciences Za Slovankou 318200 PragueCzech Republic Helmholtz-Zentrum Dresden-Rossendorf Institut fur Strahlenphysik01328 DresdenGermany AWE plc AldermastonReadingBerkshire RG74PRUK OxCHEDS Clarendon LaboratoryDepartment of PhysicsUniversity of OxfordOxford OX13PUUK CIFS The Blackett LaboratoryImperial College LondonLondon SW72AZUK Centro de Laseres pulsados(CLpU) 37185 VillamayorSalamancaSpain Beijing National Laboratory for Condensed Matter physics Institute of PhysicsChinese Academy of SciencesBeijing 100190China Institute of physics of the Czech Academy of Sciences Na Slovance 218221 PragueCzech Republic School of physical Sciences University of Chinese Academy of SciencesBeijing 100049China Department of physics Scottish Universities Physics Alliance(SUPA)University of StrathclydeGlasgow G40NGUK Laboratory pIIM University Aix-Marseille-CNRS13397 MarseilleFrance Institute of plasma physics and Laser Microfusion 01-497 WarsawPoland The Blackett Laboratory Imperial College LondonLondon SW72AZUK pHELIX Group GSI Helmholtzzentrum fur SchwerionenforschungD-64291 DarmstadtGermany

This paper provides an up-to-date review of the problems related to the generation,detection and mitigation of strong electromagnetic pulses created in the interaction of high-power,high-energy laser pulses with different types of solid *** includes new experimental data obtained independently at several international *** mechanisms of electromagnetic field generation are analyzed and considered as a function of the intensity and the spectral range of emissions they *** major emphasis is put on the GHz frequency domain,which is the most damaging for electronics and may have important *** physics of electromagnetic emissions in other spectral domains,in particular THz and MHz,is also *** theoretical models and numerical simulations are compared with the results of experimental measurements,with special attention to the methodology of measurements and complementary *** the underlying physical processes is the basis for developing techniques to mitigate the electromagnetic threat and to harness electromagnetic emissions,which may have promising applications.

关键词： electromagnetic pulses high-power lasers diagnostics mitigation techniques

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：