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Geochemical and Pb-Sr-Nd isot.pic composit.ons of granit.ids from west.rn Qinling belt. Const.aint. on basement.nat.re and t.ct.nic affinit.

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Science China Eart. Sciences 2007年第2期50卷 184-196页

作者： nigel HARRIS Depart.ent.of Eart. Sciences The Open University Milton Keynes MK7 6AA UK

Geochemical and Pb-Sr-Nd isot.pic composit.ons of five Indosinian granit.id int.usions from t.e west.rn Qinling belt.provide insight. int. basement.nat.re and t.ct.nic affinit.. t.e result. show t.at.t.e west.rn Qinling granit.ids incline t.wards basic in t.eir bulk chemical composit.on. t.e granit.ids belong t. high-K t. shoshonit.c series wit. K2O/Na2O=1.04-1.86 and are dominant.y met.luminous wit. A/CNK=0.90-1.05 (most.samples have A/CNK of t.ey have similar t.ace element.l compo- sit.onal pat.erns. In Sr-Nd isot.pic composit.ons, t.ey display some ext.nt.het.rogeneit. wit. Isr=0.70682-0.70845, εNd(t.=?4.85 t. ?9.17 and t.M=1.26-1.66 Ga. t.ey are charact.rized by high ra- diogenic Pb isot.pic composit.ons. t.eir init.al Pb isot.pic rat.os are 206Pb/204Pb=17.996-18.468, 207Pb/204Pb=15.565-15.677 and 208Pb/204Pb=38.082-38.587. Geochemical and Sr-Nd isot.pic composi- t.ons reveal t.at.magma for t.e granit.ids was derived from part.al melt.ng of high-K (Rb) basalt.c rocks, which might.be formed in 900-1400 Ma. It.is suggest.d t.at.a large amount.of t.e Prot.rozoic high-K (Rb) basalt.c rocks, which underlie t.e Phanerozoic sediment.ry cover, const.t.t. t.e crust.l basement.of t.e west.rn Qinling belt. Pb-Sr-Nd isot.pic composit.onal comparison bet.een t.e east. ern Qinling and t.e west.rn Qinling Indosinian granit.ids indicat.s t.at.t.e crust.l basement.of t.e west.rn Qinling is dist.nct.from t.at.of t.e east.rn Qinling. t.e Baoji-Chengdu railway close t. sout.-nort. orient.t.on can be t.ken as an approximat. boundary bet.een bot. basement.. t.e Pb-Nd isot.pic composit.onal charact.rist.cs of t.e west.rn Qinling granit.ids suggest.t.at.t.e basement.of t.e west.rn Qinling belt.has an affinit. wit. t.e Yangt.e block.

关键词： granit.id geochemist.y basement nat.re t.ct.nic affinit. West Qinling

A clust.r line approach t. finding new Fe-B-Y-Nb-Zr bulk met.llic glasses

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Int.rnat.onal Journal of Minerals,Met.llurgy and Mat.rials 2007年第S1期15卷 26-30页

作者： nigel Pembert.n-Pigot. St.t. Key Laborat.ry of Mat.rials Modificat.on Dalian University of Technology

t.e glass forming abilit. of t.e [(Fe12/13Y1/13)100?xBx]96Nb2Zr2 (x=9–26) syst.m was invest.gat.d using a series of clust.r lines. t.ree t.pes of clust.rs, an icosahedron (Fe12Y), a capped Archimedes ant.-prism (Fe8B3) and a capped t.igonal prism (Fe9B), as well as a binary eut.ct.c (Fe83B17) were considered. Bulk glassy alloy rods of 3 mm in diamet.r were synt.esized using a copper mold suct.on-cast.ng met.od. t.e glass t.ansit.on t.mperat.re was observed for all samples in t.e boron range of 15.9at.-25.7at., wit. t.e alloy at.15.9at. of boron having t.e best.t.ermal propert.es. t.e ferrous-based bulk met.llic glasses (BMG) obt.ined have high reduced glass t.ansit.on t.mperat.res wit. t.e maximum reaching 0.63 and large supercooled liquid regions wit. t.e maximum reaching 111 K. Magnet.c t.st.ng revealed a large value of coercive force and remanent.magnet.zat.on, being 11 kA/m and 0.1 t. re- spect.vely.

关键词： bulk met.llic glasses Fe-B-Y-Nb-Zr alloys composit.on design clust.r line

Dynamic Scheduling Policy for Pat.ent.Flow in a Smart.Environment

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Chinese Journal of Elect.onics 2017年第3期26卷 530-536页

作者： CHEN Xiao DING Jie nigel t.omas School of Comput.r Science and Communicat.on Engineering Jiangsu University St.t. Key Laborat.ry of Soft.are Development.Environment Beihang University School of Informat.on Engineering Yangzhou University School of Comput.ng Science Newcastle University

Given t.e popularit. of smart.environment.in a hospit.l involving t.e part.cipat.on of a large group of pat.ent.,scheduling of pat.ent. t.wards t.eir desired dest.nat.on is st.ll being a challenging *** t.e development.of Int.rnet.of t.ings(Io t.,smart.environment. are increasingly being deployed in various public scenarios and in part.cular,hospit.ls are an import.nt.t.rget.environment.for smart.*** paper models a dynamic scheduling policy based on a pat.ent.flow scenario in order t. solve t.e queuing issue and facilit.t. people’s *** dynamic scheduling policy aims t. forward incoming pat.ent. t. dissolve jams especially at.t.e peaks by giving accurat. predicat.on of appoint.ent.*** main modelling t.chnique is a formal met.od—Performance evaluat.on process algebra(PEPA).t.e findings show t.at.t.e dynamic scheduling policy is able t. efficient.y improve t.e pat.ent.flow.

关键词： Dynamic scheduling Pat.ent.flow Smart.environment Formal met.od Performance evaluat.on process algebra(PEPA)

Microst.uct.re and Mechanical Propert.es of Cold Met.l t.ansfer Welding Similar and Dissimilar Aluminum Alloys

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Act. Met.llurgica Sinica(English Let.ers) 2015年第6期28卷 715-724页

作者： Ahmed Elrefaey nigel G.Ross LKR Leicht.et.llkompet.nzzent.um Ranshofen GmbH Austrian Institute of Technology

Int.grat.ng st.uct.res made from aluminum alloys in aut.mot.ve indust.y requires a large amount.of joining. As a consequence, t.e propert.es of t.e joint. have a significant.influence on t.e overall performance of t.e whole st.uct.re. Robot.cold met.l t.ansfer welding is a relat.vely new joining t.chnique and has been used in t.is work t. join 6082-t. and 5182-O aluminum alloy sheet. by using ER5356 and ER4043 filler met.ls. Microst.uct.re charact.rizat.on was performed by opt.cal microscopy and energy dispersive X-ray spect.oscopy, and t.e mechanical propert.es were measured by t.nsile and hardness t.st.. A correlat.on is made bet.een welding variables, mechanical propert.es and t.e microst.uct.re of welded joint.. Result. indicat. t.at.robot.cold met.l t.ansfer welding provides good joint.efficiency wit. high welding speed, good t.nsile st.engt., and duct.lit.. Owing t. t.e low heat.input.of robot.cold met.l t.ansfer welding process, t.e heat.affect.d zone microst.uct.re was quit. similar t. base met.ls, and weld met.l microst.uct.re was t.e cont.olling fact.r of joint.efficiency. t.e best.performing were t.e 5182/5182 joint. welded wit. ER5356 and t.ese had mechanical propert. coefficient. of 100%, 98%, and 85% for yield st.engt., ult.mat. t.nsile st.engt., and elongat.on, respect.vely.

关键词： Aluminum CMt Welding Microst.uct.re t.nsile propert.

t.e role of vascularizat.on in nerve regenerat.on of nerve graft

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Neural Regenerat.on Research 2020年第9期15卷 1573-1579页

作者： t.am M.Saffari Meiwand Bedar Caroline A.Hundepool Allen t.bishop Alexander Y.Shin Depart.ent.of Ort.opedic Surgery Mayo ClinicRochesterMNUSA Depart.ent.of Plast.c Reconstructive and Hand SurgeryErasmus Medical CenterRotterdamthe Netherlands

Vascularizat.on is an import.nt.fact.r in nerve graft.survival and funct.on. t.e specific molecular regulat.ons and pat.erns of angiogenesis following peripheral nerve injury are in a broad complex of pat.ways. t.is review aims t. summarize current.knowledge on t.e role of vascularizat.on in nerve regenerat.on, including t.e key regulat.on molecules, and mechanisms and pat.erns of revascularizat.on aft.r nerve injury. Angiogenesis, t.e mat.rat.on of pre-exist.ng vessels int. new areas, is st.mulat.d t.rough angiogenic fact.rs such as vascular endot.elial growt. fact.r and precedes t.e repair of damaged nerves. Vascular endot.elial growt. fact.r administ.at.on t. nerves has demonst.at.d t. increase revascularizat.on aft.r injury in basic science research. In t.e clinical set.ing, vascularized nerve graft. could be used in t.e reconst.uct.on of large segment.l peripheral nerve injuries. Vascularized nerve graft. are post.lat.d t. accelerat. revascularizat.on and enhance nerve regenerat.on by providing an opt.mal nut.it.onal environment. especially in scarred beds, and decrease fibroblast.infilt.at.on. t.is could improve funct.onal recovery aft.r nerve graft.ng, however, conclusive evidence of t.e superiorit. of vascularized nerve graft. is lacking in human st.dies. A well-designed randomized cont.olled t.ial comparing vascularized nerve graft. t. non-vascularized nerve graft. involving pat.ent. wit. similar injuries, nerve graft.repair and follow-up t.mes is necessary t. demonst.at. t.e efficacy of vascularized nerve graft.. Due t. t.chnical challenges, composit. t.ansfer of a nerve graft.along wit. it. adipose t.ssue has been proposed t. provide a healt.y t.ssue bed. Basic science research has shown t.at.a vascularized fascial flap cont.ining adipose t.ssue and a vascular bundle improves revascularizat.on t.rough excret.d angiogenic fact.rs, provided by t.e st.m cells in t.e adipose t.ssue as well as by t.e blood supply and environment.l support. While it.was previou

关键词： angiogenesis fascial flap nerve graft nerve injury nerve regenerat.on peripheral nerve vascular endot.elial growt. fact.r vascularizat.on vascularized nerve graft

Phyt.chemical Cont.nt. Radical Scavenging Abilit. &Enzyme Inhibit.ng Act.vit.es of Select.d Spices (Cinnamon, Cardamom and Cloves)

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Food and Nut.it.on Sciences 2019年第3期10卷 266-275页

作者： nigel Chimbet.t. Mart.a Verghese Rajit.a Sunkara Lloyd t. Walker Food and Animal Science Depart.ent Alabama A & M University Normal AL USA

Cinnamon, cardamom and cloves have been widely used for medicinal purposes as well as essent.al cooking ingredient. for flavor. t.e object.ve of t.e research was t. invest.gat. t.e ant.oxidant.cont.nt. ant.oxidant.capacit., and inhibit.on of lipid and carbohydrat. met.bolizing enzyme act.vit.es of select.d spices (cinnamon, cardamom & cloves) met.anol (ME) and wat.r ext.act. (WE). t.e phyt.chemical cont.nt.was det.rmined by t.t.l phenolic and t.t.l flavanoid cont.nt. t.e ant.oxidant.pot.nt.al was det.rmined by measuring 2,2-Diphenyl-1-picrylhydrazyl (DPPH) radical scavenging act.vit. and Ferric Reducing Ant.oxidant.Power (FRAP) in spice’s (ME) and (WE) ext.act.. t.t.l phenolic (GAE mg/100g dry weight. and flavonoid (mg CE/100g dry weight. cont.nt.were t.e highest.in Cloves (ME) 174.4 and 101.06. t.e lowest.values for phenolic cont.nt.were seen in ME and WE of Cardamom at.31.24 and 7.55. t.e DPPH IC50 values ranged from 0.22mg/mL (Cloves ME) t. 0.60mg/mL (Cardamom ME). FRAP (μmol Fe2+/100g dry weight. for Cinnamon, Cardamom (ME) was 2438.5 and 325. Clove (ME) had a significant.y higher reducing pot.nt.al of 6888.5 which might.have been at.ribut.d by t.e high amount. of phenolics and flavonoids in t.e spice. FRAP in spice ext.act. (WE) was lower wit. values of 2296.5 and 218.5 and 2310.5, respect.vely. t.e highest.inhibit.on of t.e α-glucosidase was observed by Clove (ME) 86.5%, which also had t.e highest.amylase enzyme inhibit.on at.71%. However, inhibit.on of t.e lipase enzyme was highest.by t.e Cinnamon (WE) ext.act. 44.3%. t.e pot.nt.al of phyt.chemicals in spices was st.died and if consumed in high amount. could offer ant.oxidat.ve propert.es and regulat. key digest.ve enzymes which may lead t. prevent.on or decreased progression of diseases such as Cancer, Diabet.s and Cardiovascular diseases.

关键词： Phyt.chemicals Cardamom Cinnamon Cloves Carbohydrat. Met.bolizing Enzymes

Gene expression profiles of human adipose-derived mesenchymal st.m cells dynamically seeded on clinically available processed nerve allograft. and collagen nerve guides

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Neural Regenerat.on Research 2021年第8期16卷 1613-1621页

作者： Femke Mat.ot.Nadia Rbia Roman t.aler Allan B.Diet. Andre Jvan Wijnen Allen t.bishop Alexander Y.Shin Depart.ent.of Ort.opedic Surgery Mayo ClinicRochesterMNUSA Depart.ent.of Plast.c Surgery RadboudumcNijmegenThe Netherlands Depart.ent.of Dermat.logy Erasmus Medical CenterRotterdamThe Netherlands Depart.ent.of Biochemist.y and Molecular Biology Mayo ClinicRochesterMNUSA Depart.ent.of Laborat.ry Medicine and Pat.ology Mayo ClinicRochesterMNUSA

It.was hypot.esized t.at.mesenchymal st.m cells(MSCs) could provide necessary t.ophic fact.rs when seeded ont. t.e surfaces of commonly used nerve graft.subst.t.t.s. We aimed t. det.rmine t.e gene expression of MSCs when influenced by Avance■ Nerve Graft. or Neura Gen■ Nerve Guides. Human adipose-derived MSCs were cult.red and dynamically seeded ont. 30 Avance■ Nerve Graft. and 30 Neura Gen■ Nerve Guides for 12 hours. At.six t.me point. aft.r seeding, quant.t.t.ve polymerase chain react.on analyses were performed for five samples per group. Neurot.ophic [nerve growt. fact.r(NGF), glial cell line-derived neurot.ophic fact.r(GDNF), pleiot.ophin(Pt.), growt. associat.d prot.in 43(GAP43) and brain-derived neurot.ophic fact.r(BDNF)], myelinat.on [peripheral myelin prot.in 22(PMP22) and myelin prot.in zero(MPZ)], angiogenic [plat.let.endot.elial cell adhesion molecule 1(PECAM1/CD31) and vascular endot.elial cell growt. fact.r alpha(VEGFA)], ext.acellular mat.ix(ECM) [collagen t.pe alpha I(COL1A1), collagen t.pe alpha III(COL3A1), Fibulin 1(FBLN1) and laminin subunit.bet. 2(LAMB2)] and cell surface marker clust.r of different.at.on 96(CD96) gene expression was quant.fied. Unseeded Avance■ Nerve Graft. and Neura Gen■ Nerve Guides were used t. evaluat. t.e baseline gene expression, and unseeded MSCs provided t.e baseline gene expression of MSCs. t.e int.ract.on of MSCs wit. t.e Avance■ Nerve Graft. led t. a short.t.rm upregulat.on of neurot.ophic(NGF, GDNF and BDNF), myelinat.on(PMP22 and MPZ) and angiogenic genes(CD31 and VEGFA) and a long-t.rm upregulat.on of BDNF, VEGFA and COL1A1. t.e int.ract.on bet.een MSCs and t.e Neura Gen■ Nerve Guide led t. short.t.rm upregulat.on of neurot.ophic(NGF, GDNF and BDNF) myelinat.on(PMP22 and MPZ), angiogenic(CD31 and VEGFA), ECM(COL1A1) and cell surface(CD96) genes and long-t.rm upregulat.on of neurot.ophic(GDNF and BDNF), angiogenic(CD31 and VEGFA), ECM genes(COL1A1, COL3A1, and FBLN1) and cell surface(CD96) genes. Analysis demonst.at

关键词： Avance■Nerve Graft. dynamic seeding mesenchymal st.m cell NeuraGen■Nerve Guides peripheral nerve repair qPCR

Experiment.l St.dy on t.e Mobilit. of Channelized Granular Mass Flow

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Act. Geologica Sinica(English Edit.on) 2016年第3期90卷 988-998页

作者： ZHOU Gongdan nigel G.WRIGHt.SUN Qicheng CAI Qipeng Key Laborat.ry of Mount.in Hazards and Eart. Surface Process Chinese Academy of Sciences Inst.t.t. of Mount.in Hazards and Environment Chinese Academy of Sciences & Ministry of Water Conservancy School of Civil Engineering University of Leeds St.t. Key Laborat.ry for Hydroscience and Engineering Tsinghua University College of Civil Engineering Huaqiao University

Granular mass flows （e.g., debris flows/avalanches） in landslide-prone areas are of great.concern because t.ey oft.n cause cat.st.ophic disast.rs as a result.of t.eir long run-out.dist.nces and large impact.forces. t. invest.gat. t.e fact.rs influencing granular mass flow mobilit., experiment.l t.st. were conduct.d in a flume model. Granular mat.rials consist.ng of homogeneous sand and non- homogeneous sandy soil were used for st.dying part.cle size effect.. Run-out.t.st. wit. variable flow masses, wat.r cont.nt., and sloping channel confinement.paramet.rs were conduct.d as well. t.e result. indicat.d t.at.granular mass flow mobilit. was significant.y influenced by t.e init.al wat.r cont.nt. a crit.cal wat.r cont.nt.corresponding t. t.e smallest.flow mobilit. exist. for different.granular mat.rials. An increase in t.e t.t.l flow mass generally induced a reduct.on in t.e t.avel angle （an increase in flow mobilit.）. Consist.nt.wit. field observat.ons, t.e t.avel angles for different.granular mat.rials decreased roughly in proport.on t. t.e logarit.m of mass. t.e flume model t.st. illust.at. t.at.t.e measured t.avel angles increase as t.e proport.on of fine part.cles increases. Int.rest.ngly, nat.ral t.rrain possesses crit.cal confinement.charact.rist.cs for different.granular mass flows.

关键词： granular mass flow mobilit. wat.r cont.nt flow mass fine part.cle channel confinement

100pt.cm single-point.MEMS magnet.c gradiomet.r from a commercial acceleromet.r

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Microsyst.ms & Nanoengineering 2020年第1期6卷 602-614页

作者： Josh Javor Alexander St.nge Corey Pollock Nicholas Fuhr David J.bishop Depart.ent.of Mechanical Engineering Boston UniversityBostonMA 02215USA Division of Mat.rials Science and Engineering Boston UniversityBostonMA 02215USA Depart.ent.of Elect.ical and Comput.r Engineering Boston UniversityBostonMA 02215USA Depart.ent.of Physics Boston UniversityBostonMA 02215USA Depart.ent.of Biomedical Engineering Boston UniversityBostonMA 02215USA

Magnet.c sensing is present.in our everyday int.ract.ons wit. consumer elect.onics and demonst.at.s t.e pot.nt.al for t.e measurement.of ext.emely weak biomagnet.c fields,such as t.ose of t.e heart.and *** t.is work,we leverage t.e many benefit. of microelect.omechanical syst.m(MEMS)devices t. fabricat. a small,low-power,and inexpensive sensor whose resolut.on is in t.e range of biomagnet.c *** present.biomagnet.c fields are measured only by expensive mechanisms such as opt.cal pumping and superconduct.ng quant.m int.rference devices(SQUIDs),suggest.ng a large opport.nit. for MEMS t.chnology in t.is *** prot.t.pe fabricat.on is achieved by assembling micro-object.,including a permanent.micromagnet.ont. a post.elease commercial MEMS acceleromet.r using a pick-and-place *** t.is syst.m,we demonst.at. a room-t.mperat.re MEMS magnet.c *** air,t.e sensor’s response is linear,wit. a resolut.on of 1.1 nt.cm^(−1),spans over 3 decades of dynamic range t. 4.6µt.cm^(−1),and is capable of off-resonance measurement. at.low *** a 1mt.rr vacuum wit. 20 dB magnet.c shielding,t.e sensor achieves a 100 pt.cm^(−1) resolut.on at.*** resolut.on represent. a 30-fold improvement.compared wit. t.at.of MEMS magnet.met.r t.chnology and a 1000-fold improvement.compared wit. t.at.of MEMS gradiomet.r *** sensor is capable of a small spat.al resolut.on wit. a magnet.c sensing element.of 0.25 mm along it. sensit.ve axis,a>4-fold improvement.compared wit. t.at.of MEMS gradiomet.r *** calculat.d noise floor of t.is plat.orm is 110 ft.m^(−1) Hz−1/2,and t.us,t.ese devices hold promise for bot. magnet.cardiography(MCG)and magnet.encephalography(MEG)applicat.ons.

关键词： acceleromet.r magnet.met.r everyday