检索结果-南通市图书馆

Sensitivity of diagnosis of spontaneous bacterial peritonitis is higher with the automated cell count method

World Journal of Hepatology 2024年第11期16卷 1265-1281页

作者： Juan G Acevedo-Haro Waddah Mohamed Prebashan Moodley Oliver Bendall Kris Bennett nigel keelty Sally Chan Sam Waddy Joanne Hosking Wayne Thomas Robert Tilley South West Liver Unit University Hospitals Plymouth NHS TrustPlymouth PL68DHUnited Kingdom Medical School University of PlymouthPlymouth PL68DHUnited Kingdom Intensive Care Unit University Hospitals Plymouth NHS TrustPlymouth PL68DHUnited Kingdom Medical Statistics Group Peninsula Clinical Trials UnitUniversity of PlymouthPlymouth PL68DHUnited Kingdom Haematology Service University Hospitals Plymouth NHS TrustPlymouth PL68DHUnited Kingdom Microbiology Service University Hospitals Plymouth NHS TrustPlymouth PL68DHUnited Kingdom

BACKGROUND Spontaneous bacterial peritonitis(SBP)is one of the most important complications of patients with liver cirrhosis entailing high morbidity and *** an accurate early diagnosis of this infection is key in the outcome of these *** current definition of SBP is based on studies performed more than 40 years ago using a manual technique to count the number of polymorphs in ascitic fluid(AF).There is a lack of data comparing the traditional cell count method with a current automated cell ***,current international guidelines do not mention the type of cell count method to be employed and around half of the centers still rely on the traditional manual *** To compare the accuracy of polymorph count on AF to diagnose SBP between the traditional manual cell count method and a modern automated cell counter against SBP cases fulfilling gold standard criteria:Positive AF culture and signs/symptoms of *** Retrospective analysis including two cohorts:Cross-sectional(cohort 1)and case-control(cohort 2),of patients with decompensated cirrhosis and *** cell count methods were conducted *** SBP cases had a pathogenic bacteria isolated on AF and signs/symptoms of *** A total of 137 cases with 5 positive-SBP,and 85 cases with 33 positive-SBP were included in cohort 1 and 2,***-SBP cases had worse liver function in both *** automated method showed higher sensitivity than the manual cell count:80%vs 52%,P=0.02,in cohort *** methods showed very good specificity(>95%).The best cutoff using the automated cell counter was polymorph≥0.2 cells×10^(9)/L(equivalent to 200 cells/mm^(3))in AF as it has the higher sensitivity keeping a good *** The automated cell count method should be preferred over the manual method to diagnose SBP because of its higher *** definition,using the automated method,as polymorph cell count≥0.2 cells×1

关键词： Spontaneous bacterial peritonitis Diagnosis Cirrhosis Bacterial infection Automated cell count method Manual cell count method Ascitic fluid

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：