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The Narcissistic Dilemma: Exploring NPD Traits in Hamlet from a Beauvoirian Perspective

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Journal of Literature and Art Studies 2024年第4期14卷 265-272页

作者： nida ul zafar Southwest University ChongqingChina

This research paper explores the intersection of existential philosophy and psychological disorders in William Shakespeare’s Hamlet,with a focus on Narcissistic Personality Disorder(NPD)as viewed through the existentialist lens of Simone de *** upon Beauvoir’s existentialist framework,the study delves into the complexities of identity,agency,and societal expectations as portrayed in the characters of Gertrude and *** an interdisciplinary approach,the paper examines how existential crises intertwine with narcissistic behaviors,shedding light on the psychological intricacies of Shakespeare’s iconic *** synthesizing literary analysis with psychological insights,the study offers valuable contributions to our understanding of human psychology,societal dynamics,and the timeless themes of existential authenticity portrayed in literature.

关键词： existentialism Simone de Beauvoir Narcissistic Personality Disorder Shakespeare Hamlet identity psychological complexity

Combined Role of ACC Deaminase Producing Bacteria and Biochar on Cereals Productivity under Drought

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Phyton-International Journal of Experimental Botany 2020年第2期89卷 217-227页

作者： Subhan Danish Muhammad zafar-ul-Hye Department of Soil Science Faculty of Agricultural Sciences and TechnologyBahauddin Zakariya UniversityMultan60800Pakistan Soil and Water Testing Laboratory PakArab Fertilizer LimitedPlantsiteMultan60800Pakistan

Most of the cereal crops are widely cultivated to fulfil the humans food *** changing climate scenario,the intensity of drought stress is continuously increasing that is adversely affecting the growth and yield of cereal *** the cereals can tolerate moderate drought to some extent,but mostly they are susceptible to severe drought *** biosynthesis of ethylene under drought stress has been *** scientists observed that inoculation of 1-aminocyclopropane-1-carboxylate(ACC)deaminase producing plant growth promoting rhizobacteria(PGPR)is an efficacious tool to overcome this *** PGPR secrete ACC deaminase which cleavage the ACC into the compounds,other than ***,secretion of growth hormones also play imperative role in enhancing the growth of the cereals under limited availability of *** addition,the use of biochar has also been recognized as another effective amendment to grant resistance against *** application improves the soil physiochemical attributes i.e.,porosity,nutrients retention and water holding capacity which decrease the loss of water and increase its *** recent era,the idea of coapplication of ACC deaminase producing PGPR and biochar is becoming popular which might be more efficient to use water under drought *** aim of current review is to combine the facts and understanding of this novel idea to grant maximum resistance to crops against drought *** scientists have observed significant improvement in yield of cereal crops by combined use of ACC deaminase producing PGPR and ***,more research is suggested for deep understanding of complex synergistic mechanism of ACC deaminase activity in combination with biochar.

关键词： ACC deaminase biochar cereals drought ethylene PGPR yield

A Differential Quadrature Based Approach for Volterra Partial Integro-Differential Equation with a Weakly Singular Kernel

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Computer Modeling in Engineering & Sciences 2020年第9期124卷 915-935页

作者： Siraj-ul-Islam Arshed Ali Aqib zafar Iltaf Hussain Department of Basic Sciences and Islamiat University of Engineering and Technology PeshawarKhyber PakhtunkhwaPakistan Department of Mathematics Islamia College PeshawarKhyber PakhtunkhwaPakistan

Differential quadrature method is employed by numerous researchers due to its numerical accuracy and computational efficiency,and is mentioned as potential alternative of conventional numerical *** this paper,a differential quadrature based numerical scheme is developed for solving volterra partial integro-differential equation of second order having a weakly singular *** scheme uses cubic trigonometric B-spline functions to determine the weighting coefficients in the differential quadrature approximation of the second order spatial *** advantage of this approximation is that it reduces the problem to a first order time dependent integro-differential equation(IDE).The proposed scheme is obtained in the form of an algebraic system by reducing the time dependent IDE through unconditionally stable Euler backward method as time *** scheme is validated using a homogeneous and two nonhomogeneous test *** of the system matrix and numerical convergence of the method are analyzed for spatial and temporal domain discretization *** of results of the present approach with Sinc collocation method and quasi-wavelet method are also made.

关键词： Partial integro-differential equation differential quadrature cubic trigonometric B-spline functions weakly singular kernel

Nanosuspension enhances dissolution rate and oral bioavailability of Terminalia arjuna bark extract in vivo and in vitro

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Asian Pacific Journal of Tropical Biomedicine 2020年第4期10卷 164-171页

作者： Fatiqa zafar Nazish Jahan Khalil-Ur-Rahman Muhammad Rafique Asi Waseeq-ul-Islam zafar Department of Chemistry University of OkaraOkaraPakistan Department of Chemistry University of AgricultureFaisalabadPakistan Department of Biochemistry University of AgricultureFaisalabadPakistan Food Toxicology Lab Plant Protection DivisionNuclear Institute for Agriculture and BiologyFaisalabadPakistan Department of Computer Science COMSATS University of Information and TechnologyIslamabadPakistan

Objective:To enhance the dissolution rate and oral bioavailability of Terminalia arjuna bark extract by formulating its ***:Nanoprecipitation approach was used for the formulation of nanosuspension using polysorbate-80 as a *** formulated nanosuspension was assessed for particle size,polydispersity index,zeta potential value and for in vitro dissolution *** bioavailability studies were carried out in Wistar male albino rats by administering a single dose(50 mg/***)of the formulated nanosuspension and coarse *** storage stability of the formulated nanosuspension was determined after three months of storage at room temperature and under the refrigerated *** assay was carried out to evaluate the toxicity of the formulated nanosuspension using two mutant strains(Salmonella typhimurium TA100 and Salmonella typhimurium TA98).Results:The mean particle size of the formulated nanosuspension was 90.53 nm with polydispersity index and zeta potential values of 0.175 and-15.7 m V,*** arjuna nanosuspension showed improved dissolution rate and 1.33-fold higher oral bioavailability than its coarse *** formulated nanosuspension also showed better stability under the refrigerated condition and was non-mutagenic against both ***:Our study demonstrates that nanosuspension technology can effectively enhance the dissolution rate and oral bioavailability of Terminalia arjuna bark extract.

关键词： Terminalia arjuna Nanosuspension Bioavailability Stability Toxicity Polysorbate-80

Bioactivity analysis of the Ta(Ⅴ) doped SiO2–Ca O–Na2O–P2O5 ceramics prepared by solid state sintering method

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Progress in Natural Science:Materials International 2016年第1期26卷 41-48页

作者： Rehana Zia Madeeha Riaz nida ul nasir Farhat Saleemi Zora Kayani Safia Anjum Farooq Bashir Tousif Hussain Department of Physics Lahore College for Women University 2. Government College for Women University 3. CASP Government College

The main objective of the study was to control the degradation rate of material at a higher degradation rate improving the chemical stability of the material. Ta is known to have good chemical resistance, biocompatibility and show no adverse biological response. In the present study, Si O–NaO–Ca O–PObioceramics with different TaOcontents was prepared by solid state sintering method at 1000 °C. The as-sintered ceramics were subjected to immersion studies in stimulated body fluid(SBF) for 21 days under static condition and characterized by XRD, FTIR, SEM, and AAS. The findings of the research indicate that the addition of TaOcontrolled degradability, and all samples showed sufficient bioactivity.

关键词： Crystallization Bioactivity Ta2O5 Degradation rate Bioceramic

Plant Derived Antiviral Products for Potential Treatment of COVID-19: A Review

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Phyton-International Journal of Experimental Botany 2020年第3期89卷 437-452页

作者： Rashid Iqbal Khan Mazhar Abbas Khurram Goraya Muhammad zafar-ul-Hye Subhan Danish Institute of Hoticultural Sciences University of Agriculture FaisalabadFaisalabad38000Pakistan Office for Conservation of the Environment Diwan of Royal Court of OmanMuscat113Oman Department of Soil Science Faculty of Agricultural Sciences and TechnologyBahauddin Zakariya UniversityMultan60800Pakistan

COVID-19 caused by SARS-CoV-2 is declared global *** virus owing high resemblance with SARS-CoVand MERS-CoV has been placed in family of ***,transmission and infectivity rate of COVID-19 is quite higher as compared to other members of *** management strategy with potential drug availability will break the virus transmission chain subsequently reduce the pressure on the healthcare *** research trials are underway to develop novel efficient therapeutics against *** this review,we have discussed the origin and family of coronavirus,structure,genome and pathogenesis of virus SARS-CoV-2 inside human host cell;comparison among SARS,MERS,SARS-CoV-2 and common flu;effective management practices;treatment with immunity boosters;available medication with ongoing clinical *** suggest medicinal plants could serve as potential candidates for drug development against COVID-19 infection.

关键词： Virus human health bat SARS-CoV-2 fever Wuhan

Antibacterial Action of Chemically Synthesized and Laser Generated Silver Nanoparticles against Human Pathogenic Bacteria

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Journal of Materials Science & Technology 2016年第8期32卷 721-728页

作者： Nosheen zafar Shahzadi Shamaila Jawad Nazir Rehana Sharif Muhammad Shahid Rafique Jalees ul-Hasan Syeda Ammara Hina Khalid Department of Physics University of Engineering and Technology Lahore 54890 Pakistan Department of Microbiology University of Veterinary and Animal Sciences Lahore Pakistan Department of Physics Forman Christian College A Charted University Lahore Pakistan

Silver nanoparticles in the range of 10-40 nm were synthesized chemically and by laser ablation, em- ployed for in vitro antibacterial action against human pathogenic bacterium. Their formation was evidenced by UV-visible spectrophotometer; particle size confirmed by atomic force microscopy, crystal structure determined by X-ray diffraction and chemical composition investigated by Fourier transform infrared spec- troscopy. The calculated MIC （minimum inhibitory concentration） of chemically synthesized nanoparticles with 30-40 nm in size are 2.8 μg/mL 4.37 μg/mL 13.5μg/mL and 2.81 p.g/mL for E. coil, S. aureus, B. subtillis and Salmonella, respectively. Whereas laser ablated nanoparticles exhibit MIC of 2.10 μg/mL 2.36 μg/ mL and 2.68 μg/mL for E. coli, S. aureus and Salmonella, respectively.

关键词： Chemically synthesized and laser ablated nanoparticles UV-visible spectrophotometer Gram negative and gram positive bacteria

TrFAST: A Tool to Predict Signaling Pathway-specific Transcription Factor Binding Sites

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Genomics, Proteomics & Bioinformatics 2012年第6期10卷 354-359页

作者： Umair Seemab Qurrat ul Ain Muhammad Sulaman Nawaz zafar Saeed Sajid Rashid National Centre for Bioinformatics Quaid-i-Azam University Department of Computer Science Quaid-i-Azam University

Recent advances in the development of high-throughput tools have significantly revolutionized our understanding of molecular mech- anisms underlying normal and dysfunctional biological processes. Here we present a novel computational tool, transcription factor search and analysis tool （TrFAST）, which was developed for the in silico analysis of transcription factor binding sites （TFBSs） of sig- naling pathway-specific TFs. TrFAST facilitates searching as well as comparative analysis of regulatory motifs through an exact pattern matching algorithm followed by the graphical representation of matched binding sites in multiple sequences up to 50 kb in length. TrFAST is proficient in reducing the number of comparisons by the exact pattern matching strategy. In contrast to the pre-existing tools that find TFBS in a single sequence, TrFAST seeks out the desired pattern in multiple sequences simultaneously. It counts the GC con- tent within the given multiple sequence data set and assembles the combinational details of consensus sequence（s） located at these regions, thereby generating a visual display based on the abundance of unique pattern. Comparative regulatory region analysis of multi- ple orthologous sequences simultaneously enhances the features of TrFAST and provides a significant insight into study of conservation of non-coding cis-regulatory elements. TrFAST is freely available at http：//***/***.

关键词： TrFAST Transcription factor binding sites in silico analysis Signaling pathway Pattern searching

An Automated and Real-time Approach of Depression Detection from Facial Micro-expressions

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Computers, Materials & Continua 2022年第11期73卷 2513-2528页

作者： Ghulam Gilanie Mahmood ul Hassan Mutyyba Asghar Ali Mustafa Qamar Hafeez ullah Rehan ullah Khan nida Aslam Irfan ullah Khan Department of Artificial Intelligence Faculty of ComputingThe Islamia University of BahawalpurPakistan Department of Computer Skills Deanship of Preparatory YearNajran UniversityNajranSaudi Arabia Department of Computer Science College of ComputerQassim UniversityBuraydahSaudi Arabia Biophotonics Imaging Techniques Laboratory Institute of PhysicsThe Islamia University of BahawalpurPakistan Department of Information Technology College of ComputerQassim UniversityBuraydahSaudi Arabia Department of Computer Science College of Computer Science and Information TechnologyImam Abdulrahman Bin Faisal UniversityDammamSaudi Arabia

Depression is a mental psychological disorder that may cause a physical disorder or lead to *** is highly impactful on the socialeconomical life of a person;therefore,its effective and timely detection is *** speech and gait,facial expressions have valuable clues to *** study proposes a depression detection system based on facial expression *** features have been used for depression detection using Support Vector Machine(SVM)and Convolutional Neural Network(CNN).We extracted micro-expressions using Facial Action Coding System(FACS)as Action Units(AUs)correlated with the sad,disgust,and contempt features for depression detection.A CNN-based model is also proposed in this study to auto classify depressed subjects from images or videos in *** have been performed on the dataset obtained from Bahawal Victoria Hospital,Bahawalpur,Pakistan,as per the patient health questionnaire depression scale(PHQ-8);for inferring the mental condition of a *** experiments revealed 99.9%validation accuracy on the proposed CNN model,while extracted features obtained 100%accuracy on ***,the results proved the superiority of the reported approach over state-of-the-art methods.

关键词： Depression detection facial micro-expressions facial landmarked images