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Monomeric C-reactive protein:a link between chronic inflammation and neurodegeneration?

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Neural Regeneration Research 2024年第8期19卷 1643-1644页

作者： nicoleta Arnaut Ylenia Pastorello Mark Slevin George Emil Palade University of Medicine PharmacyScience and TechnologyTârgu MuresRomania Department of Anatomy and Embryology George Emil Palade University of MedicinePharmacyScience and TechnologyTârgu MuresRomania Center for Advanced Medical and Pharmaceutical Research(CCAMF) George Emil Palade University of MedicinePharmacyScience and TechnologyTârgu MuresRomania

Pre-diabetic insulin resistance is associated with sub-clinical inflammation and concomitant increase in systemic C-reactive protein(CRP)*** 2 diabetes mellitus(T2DM)patients register even higher chronic levels of inflammation,with excess circulating CRP originating from both typical hepatic synthesis,and also visceral white adipose tissue.

关键词： inflammation reactive clinical

Hypoglycaemia in screening oral glucose tolerance test in pregnancy with low birth weight fetus

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World Journal of Experimental Medicine 2024年第3期14卷 119-121页

作者： nicoleta Gana Iulia Huluta Nicolae Gica Department of Obstetrics and Gynecology Filantropia Clinical Hospital BucharestBucharest 099098Romania Department of Obstetrics and Gynecology Carol Davila University of Medicine and PharmacyBucharest 098909Romania

Maternal hypoglycemia,a condition characterized by lower than normal blood glucose levels in pregnant women,has been increasingly associated with adverse pregnancy outcomes,including low birth weight(LBW)in ***,defined as a birth weight of less than 2500 g,can result from various factors,including maternal nutrition,health status,and metabolic conditions like *** hypoglycemia may affect fetal growth by altering the supply of essential nutrients and oxygen to the fetus,leading to restricted fetal development and *** condition poses significant risks not only during pregnancy but also for the long-term health of the child,increasing the likelihood of developmental delays,health issues,and chronic conditions later in *** in this area has focused on understanding the mechanisms through which maternal hypoglycemia influences fetal development,with studies suggesting that alterations in placental blood flow and nutrient transport,as well as direct effects on fetal insulin levels and metabolism,may play a *** the potential impact of maternal hypoglycemia on neonatal health outcomes,early detection and management are crucial to minimize risks for LBW and its associated *** investigations are needed to fully elucidate the complex interactions between maternal glucose levels and fetal growth,as well as to develop targeted interventions to support the health of both mother and *** these relationships is vital for improving prenatal care and outcomes for pregnancies complicated by hypoglycemia.

关键词： Glucose tolerance test Low birth weight Hypoglycaemia High-risk pregnancy Neonatal outcome

Assessment of Contamination Degree of Oil Residues on a Former Agricultural Site

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Journal of Agricultural Science and Technology(A) 2024年第2期14卷 67-82页

作者： Marinela Florica Bodog Emil Catalin Schiopu Ghita Cristian Crainic Andra nicoleta Lazar Department of Forestry and Forest Engineering University of OradeaBihor 418013Romania Department of Energy Environment and AgritourismFaculty of Engineering“Constantin Brancuși”UniversityTârgu Jiu 210185GorjRomania Department of Agriculture-Horticulture University of OradeaBihor 418013Romania

In this study,our goal is to identify the land surface that has been polluted/degraded by petroleum products or other identified causes through laboratory analysis,to assess the depth of current contamination and to identify the specific causes of *** level of contamination will be assessed by analyzing a total of 90 soil samples,both within the first 30 cm depth and within the 30-60 cm *** potential impact of the petroleum activities and their effects on the environment and agricultural development in the area will be evaluated by studying the distribution of the chemical elements analyzed,particularly total petroleum hydrocarbons(TPH).In addition,a thematic map was created using MapSys 10.0 software based on their distribution,indicating the polluted areas using color codes and *** analysis and mapping revealed that 7,473 square meters of the site were severely contaminated at 30 cm,representing approximately 25% of the site.

关键词： Degradation oil pollution residues soil surface thematic map

THE MAIN INVARIANTS OF A COMPLEX FINSLER SPACE

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Acta Mathematica Scientia 2014年第4期34卷 995-1011页

作者： nicoleta ALDEA Gheorghe MUNTEANU Department of Mathematics and Informatics Transilvania UniversityIuliu Maniu 50Bra?sov 500091Romania

In this paper we extend the results obtained in [3], where are investigated the general settings of the two-dimensional complex Finsler manifolds, with respect to a local complex Berwahl frame. The geometry of such manifolds is controlled by three real invari- ants which live on T＇M： two horizontal curvature invariants K and W and one vertical curvature invariant I. By means of these invariants are defined both the horizontal and the vertical holomorphic sectional curvatures. The complex Landsberg and Berwald spaces are of particular into, rest. Complex Berwald spaces coincide with K/ihler spaces, in the two - dimensional case, We establish the necessary and sufficient condition under which K is a constant and we obtain a characterization for the Kghler purely Hermitian spaces by the fact K = W=constant and I = 0. For the class of complex Berwald spaces we have K =W = 0. Finally, a classitication of two-dimensional complex Finsler spaces for which the horizontal curvature satisfies a special property is obtained.

关键词： Berwald frame complex Landsberg space complex Berwald space holomorphic sectional curvature

GRAFTED STYRENE-DIVINYLBENZENE COPOLYMERS CONTAINING BENZALDEHYDES AND THEIR WITTIG REACTIONS WITH VARIOUS PHOSPHONIUM SALTS

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Chinese Journal of Polymer Science 2005年第6期23卷 651-656页

作者： Adriana Popa Gheorghe Ilia Aurelia Pascariu Smaranda Iliescu nicoleta Plesu Institute of Chemistry Romanian Academy Bd.Mihai Viteazul 24 R-300223 TimisoaraRomania

A chloromethylated styrene-divinylbenzene copolymer support system functionalized with 4-benzaldehyde and 2-benzaldehyde was prepared. The degree of functionalization with aldehyde groups is well suited for the subsequent use of the products as Wittig reagents. The polymer bound aldehyde was reacted with Wittig reagents to give olefin groups grafted on styrene-divinylbenzene copolymers. The reactions were carded out in phase transfer catalysis conditions. A simple procedure for the calculation of the degree of functionalization and the statistical modeling of the structural repetitive unit of the copolymer are reported.

关键词： Chloromethylated styrene-divinylbenzene copolymer 4-Benzaldehyde 2-Benzaldehyde Phase-transfer catalysis Wittig reaction

Cooling rate effects on the structure and transformation behavior of Cu-Zn-Al shape memory alloys

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International Journal of Minerals,Metallurgy and Materials 2014年第11期21卷 1109-1114页

作者： nicoleta-Monica Lohan Marius-Gabriel Suru Bogdan Pricop Leandru-Gheorghe Bujoreanu Faculty of Materials Science and Engineering The "Gheorghe Asachi" Technical UniversityIasi Bd. D. Mangeron 61A 700050 Iasi Romania

Different fragments of a hot-rolled and homogenized Cu–Zn–Al shape memory alloy（SMA） were subjected to thermal cycling by means of a differential scanning calorimetric（DSC） device. During thermal cycling, heating was performed at the same constant rate of increasing temperature while cooling was carried out at different rates of decreasing temperature. For each cooling rate, the temperature decreased in the same thermal interval. During each cooling stage, an exothermic peak（maximum） was observed on the DSC thermogram. This peak was associated with forward martensitic transformation. The DSC thermograms were analyzed with PROTEUS software： the critical martensitic transformation start（Ms） and finish（Mf） temperatures were determined by means of integral and tangent methods, and the dissipated heat was evaluated by the area between the corresponding maximum plot and a sigmoid baseline. The effects of the increase in cooling rate, assessed from a calorimetric viewpoint, consisted in the augmentation of the exothermic peak and the delay of direct martensitic transformation. The latter had the tendency to move to lower critical transformation temperatures. The martensite plates changed in morphology by becoming more oriented and by an augmenting in surface relief, which corresponded with the increase in cooling rate as observed by scanning electron microscopy（SEM） and atomic force microscopy（AFM）.

关键词： copper alloys shape memory effect microstructure phase transformations martensite cooling rate differential scanning calo-rimetry

Iron casting skin management in no-bake mould – Effects of magnesium residual level and mould coating

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China Foundry 2015年第3期12卷 222-230页

作者： Mihai Chisamera nicoleta Ivan Iulian Riposan Stelian Stan POLITEHNICA University of Bucharest

The relative performance of coatings for furan resin sand moulds [P-toluol sulphonic acid(PTSA) as hardener] [FRS-PTSA moulds], was compared by analyzing the surface layer for degenerated graphite in Mg treated iron with 0.020 wt.% to 0.054 wt.% Mgres. It was found that the iron nodularising potential(Mg, Ce, La content) and whether the mould coatings contained S, or were capable of desulphurizing were important factors. These moulds have S in the PTSA binder, which aggravates graphite degeneration in the surface layer, depending strongly on the Mgres with lower Mgres increasing the layer thickness. The application of a mould coating strongly influenced graphite deterioration in the surface layer of castings. It either promoted graphite degeneration to less compact morphologies when using S-bearing coatings, or conversely, limited the surface layer thickness using desulphurization type coatings. Independently of the S-source at the metal – mould interface, the presence of sulphur had an adverse effect on graphite quality at the surface of Mg-treated irons, but its negative effect could also reach the graphite phase within the casting section. If the coatings employed desulphurization materials, such as Mg O, or a mixture(Ca O + Mg O + Talc) or Mgbearing Fe Si, they protected the graphite shape, improving graphite nodularity, at the metal – mould interface, and so decreased the average layer thickness in FRS-PTSA moulds. Fe Si Mg was highly efficient in minimizing the casting skin by improving graphite nodularity. It is presumed that the Mg O or(Mg O + Ca O + Talc) based coatings acted to remove any S released by the mould media. The Mg-Fe Si coatings also reacted with S from the mould but additionally supplemented the Mg nodularising potential prior to solidification. This dual activity is achievable with coatings containing active magnesium derived from fine Mg-Fe Si materials.

关键词： ductile iron compacted graphite iron surface layer graphite degeneration resin bonded sand mould Mg-bearing mould coating S-bearing mould coating

A Feasibility Study of Selling International Car Brands in China （SEAT）

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A Feasibility Study of Selling International Car Brands in C...

作者： Popa nicoleta-Elena 浙江科技学院

学位级别：硕士

This research uses the analysis of SEAT Company to conclude that the Spanish manufacturer which is a Volkswagen owned *** company has a history in manufacturing SUV’s and Sedans and as such can verily provide all the features its customers demand,it focuses its production mostly on low emission vehicles and can offer a competitive price on the *** has verily been discovered that the Chinese don’t know much about SEAT and its vehicles,they have few information to access that’s why a big part of them are not willing to purchase the *** Chinese costumers are still very sensitive to pricing policies,so offering a high price when the competition is very fierce is not a suitable *** appreciate different values in vehicles;some find quality and safety essential,while others care more about brand or *** understanding and complying with all costumer needs has set the performance of the manufacturer on market very *** have been three of the main causes why good quality vehicles manufactured by SEAT failed to succeed in China in its first *** view of this situation,this research proposes to strengthen the brand building of SEAT,by researching Chinese people’s preferences in vehicles,finding the locations that have the highest purchasing potential,suggesting the right pricing policy and by researching advertising methods suitable for China’s national conditions and promote the development of SEAT on the Chinese *** achieve its objectives,the research utilized the relevance of both quantitative and qualitative methodologies where primary sources of data were deployed to compliment the secondary sources of information harvested in the field for procession.

关键词：

Exploring the asymmetric effect of COVID‑19 pandemic news on the cryptocurrency market:evidence from nonlinear autoregressive distributed lag approach and frequency domain causality

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Financial Innovation 2023年第1期9卷 692-749页

作者： Ştefan Cristian Gherghina Liliana nicoleta Simionescu Department of Finance Bucharest University of Economic Studies6 Romana Square010374 BucharestRomania

This paper explores the asymmetric effect of COVID-19 pandemic news,as measured by the coronavirus indices(Panic,Hype,Fake News,Sentiment,Infodemic,and Media Coverage),on the cryptocurrency *** daily data from January 2020 to September 2021 and the exponential generalized autoregressive conditional heter-oskedasticity model,the results revealed that both adverse and optimistic news had the same effect on Bitcoin returns,indicating fear of missing out behavior does not ***,when the nonlinear autoregressive distributed lag model is esti-mated,both positive and negative shocks in pandemic indices promote Bitcoin’s daily changes;thus,Bitcoin is resistant to the SARS-CoV-2 pandemic crisis and may serve as a hedge during market *** analysis of frequency domain causality supports a unidirectional causality running from the Coronavirus Fake News Index and Sentiment Index to Bitcoin returns,whereas daily fluctuations in the Bitcoin price Granger affect the Coronavirus Panic Index and the Hype *** findings may have significant policy implications for investors and governments because they highlight the impor-tance of news during turbulent *** empirical results indicate that pandemic news could significantly influence Bitcoin’s price.

关键词： COVID-19 Bitcoin NARDL EGARCH Frequency domain causality