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CAIPIRINHA-accelerated T1w 3D-FLASH for small-bowel MR imaging in pediatric patients with Crohn's disease:assessment of image quality and diagnostic performance

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World Journal of Pediatrics 2016年第4期12卷 455-462页

作者： Mengxia Li Anke Dick nicole hassold Thomas Pabst Thorsten Bley Herbert Köstler Henning Neubauer Department of Radiation Oncology University Hospital Wuerzburg97080 WuerzburgGermany Department of Pediatrics University Hospital Wuerzburg97080 WuerzburgGermany Department of Diagnostic and Interventional Radiology University Hospital Wuerzburg97080 WuerzburgGermany

Background:The“Controlled Aliasing In Parallel Imaging Results In Higher Acceleration”(CAPIRINHA)technique greatly accelerates T1w 3D fast low angle shot(FLASH)scans while maintaining high image *** studied image quality and conspicuity of inflammatory lesions on CAIPIRINHA-accelerated imaging for pediatric small-bowel magnetic resonance imaging(MRI).Methods:Forty-four consecutive patients(mean 14±3 years,18 girls)underwent small-bowel MRI(MR enterography,MRE)at 1.5 T including diffusion-weighted imaging(DWI),contrast-enhanced CAIPIRINHA 3D-FLASH and standard 2D-FLASH ***’s disease(CD)was confirmed in 26 patients,18 patients served as *** blinded readings were performed for grading of image quality and conspicuity of CD lesions on CAIPIRINHA FLASH and standard FLASH images in comparison to a reference standard comprising imaging and endoscopic ***:CAIPIRINHA FLASH yielded significantly higher image quality with good inter-observer agreement(κ=0.68)and showed better visual delineation in 40%of the assessed bowel lesions,as compared to standard *** was full agreement for identification of CD patients between CAIPIRINHA and standard *** FLASH detected two small-bowel lesions that were not seen on standard *** revealed additional inflammatory lesions inconspicuous on contrast-enhanced *** showed an overall diagnostic accuracy of 93%.Conclusion:We present first evidence that CAIPIRINHA greatly accelerates T1w imaging in paediatric MRE without trade-off in image quality or lesion conspicuity and is thus preferable to standard FLASH imaging.

关键词： CAIPIRINHA Crohn's disease FLASH pediatrics small-bowel MRI

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