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GeSnOI mid-infrared laser technology

2020年

作者： (法)乔立伟(nicolas jolivot)

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Light(Science & Applications) 2021年第12期10卷 2408-2420页

作者： Binbin Wang Emilie Sakat Etienne Herth Maksym Gromovyi Andjelika Bjelajac julien Chaste Gilles Patriarche Philippe Boucaud Frédéric Boeuf nicolas Pauc Vincent Calvo jérémie Chrétien Marvin Frauenrath Alexei Chelnokov Vincent Reboud jean-Michel Hartmann Moustafa El Kurdi UniversitéParis-Saclay CNRSC2N10 boulevard Thomas Gobert91120 PalaiseauFrance UniversitéCôte d’Azur CNRSCRHEARue Bernard Grégory06905 Sophia-AntipolisFrance STMicroelectronics Rue Jean Monnet38054 CrollesFrance UniversitéGrenoble Alpes CEAIRIG-DePhy17 rue des Martyrs38000 GrenobleFrance UniversitéGrenoble Alpes CEALeti17 rue des Martyrs38000 GrenobleFrance

GeSn alloys are promising materials for CMOS-compatible mid-infrared lasers ***,Sn alloying and tensile strain can transform them into direct bandgap *** growing laser technology however suffers from a number of limitations,such as poor optical confinement,lack of strain,thermal,and defects management,all of which are poorly discussed in the ***,a specific GeSn-on-insulator(GeSnOI)stack using stressor layers as dielectric optical claddings is demonstrated to be suitable for a monolithically integration of planar Group-IV semiconductor lasers on a versatile photonic platform for the near-and mid-infrared spectral ***-shape resonators on mesa structures were fabricated from GeSnOI,after bonding a Ge_(0.9)Sn_(0.1) alloy layer grown on a Ge strain-relaxed-buffer,itself on a Si(001)*** GeSnOI microdisk mesas exhibited significantly improved optical gain as compared to that of conventional suspended microdisk resonators formed from the as-grown *** further show enhanced vertical out-coupling of the disk whispering gallery mode in-plane radiation,with up to 30%vertical out-coupling *** a result,the GeSnOI approach can be a valuable asset in the development of silicon-based mid-infrared photonics that combine integrated sources in a photonic platform with complex lightwave engineering.

关键词： GeSn OI coupling

High-resolution multimodal flexible coherent Raman endoscope

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Light(Science & Applications) 2018年第1期7卷 932-939页

作者： Alberto Lombardini Vasyl Mytskaniuk Siddharth Sivankutty Esben Ravn Andresen Xueqin Chen jérôme Wenger Marc Fabert nicolas joly Frédéric Louradour Alexandre Kudlinski Hervé Rigneault Aix-Marseille Univ CNRSCentrale MarseilleInstitut FresnelMarseilleFrance Laboratoire de Physique des Lasers Atomes et Molécules UMR 8523CNRSUniversitéLille59000 LilleFrance CNRS XLIMUMR 7252Universitéde Limoges87060 LimogesFrance Department of Physics Max Planck Institute for the Science of LightUniversity of Erlangen Nuremberg91058 ErlangenGermany

Coherent Raman scattering microscopy is a fast,label-free,and chemically specific imaging technique that shows high potential for future in vivo optical ***,the imaging depth in tissues is limited to the sub-millimeter range because of absorption and *** of coherent Raman imaging using a fiber endoscope system is a crucial step towards imaging deep inside living tissues and providing information that is inaccessible with current microscopy *** now,the development of coherent Raman endoscopy has been hampered by several issues,mainly related to the fiber delivery of the excitation pulses and signal ***,we present a flexible,compact,coherent Raman,and multimodal nonlinear endoscope(4.2mm outer diameter,71mm rigid length)based on a resonantly scanned hollow-core Kagomé-lattice double-clad *** fiber design enables distortion-less,background-free delivery of femtosecond excitation pulses and back-collection of nonlinear signals through the same ***-micrometer spatial resolution over a large field of view is obtained by combination of a miniature objective lens with a silica microsphere lens inserted into the fiber *** demonstrate high-resolution,high-contrast coherent anti-Stokes Raman scattering,and second harmonic generation endoscopic imaging of biological tissues over a field of view of 320μm at a rate of 0.8 frames per *** results pave the way for intraoperative label-free imaging applied to real-time histopathology diagnosis and surgery guidance.

关键词： fiber scattering millimeter

Hysteresis Loops and Phase Diagrams of the Spin-1 Ising Model in a Transverse Crystal Field

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Chinese Physics Letters 2012年第1期29卷 194-197页

作者： S.Bouhou I.Essaoudi A.Ainane M.Saber j.j.de Miguel M.Kerouad Laboratoire de Physique des Materiaux et Modelisations des Systemes Unite Associee au CNRST-URAC 08Department of PhysicsFaculty of SciencesUniversity of Moulay IsmailB.P.11201MeknesMorocco Max-Planck-Institut fur Physik Complexer Systeme Nohnitzer Str.38D-01187 DresdenGermany Dpto.Fisica de la Materia Condensada C-3 and Institut of Materials Sciences“Nicolas Cabrera”Univ.AutonomaCantoblanco E-28049-MadridSpain

Within the framework of the effective-field theory with a probability distribution technique,which accounts for the self-spin correlation functions,the ferromagnetic spin-1 Ising model with a transverse crystal field on honeycomb,square and simple cubic lattices is *** have investigated the effect of the transverse crystal field on the phase diagrams,magnetization,hysteresis loops and χ_(z,h) of the system.A number of interesting phenomena of the system are discussed.

关键词： transverse Ising crystal

Spontaneous and stimulated electron-photon interactions in nanoscale plasmonic near fields

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Light(Science & Applications) 2021年第5期10卷 867-880页

作者： Matthias Liebtrau Murat Sivis Armin Feisto Hugo Lourenco-Martins nicolas Pazos-Pérez Ramon A.Alvarez Puebla F.javier Garcia de Abajo Albert Polman Claus Ropers Center for Nanophotonics AMOLF1098 XG AmsterdamThe Netherlands th Physical Institute-Solids and Nanostructures University of GÖttingen37077 GÖttingenGermany Max Plank Institute for Biophysical Chemistry 37077 GottingenGermany Department of Physical Chemistry and EMaS Universitat Rovira i Virgili43007 TarragonaSpain ICREA-Institucio Catalana de Recerca i Estudis Avangats 08010 BarcelonaSpain ICFO-Institut de Ciencies Fotoniques The Barcelona Institute of Science and Technology08860 Castelldefels(Barcelona)Spain

The interplay between free electrons,light,and matter offers unique prospects for space,time,and energy resolved optical material characterization,structured light generation,and quantum information ***,we study the nanoscale features of spontaneous and stimulated electron–photon interactions mediated by localized surface plasmon resonances at the tips of a gold nanostar using electron energy-loss spectroscopy(EELS),cathodoluminescence spectroscopy(CL),and photon-induced near-field electron microscopy(PINEM).Supported by numerical electromagnetic boundary-element method(BEM)calculations,we show that the different coupling mechanisms probed by EELS,CL,and PINEM feature the same spatial dependence on the electric field distribution of the tip ***,the electron–photon interaction strength is found to vary with the incident electron velocity,as determined by the spatial Fourier transform of the electric near-field component parallel to the electron *** the tightly confined plasmonic tip resonances,our calculations suggest an optimum coupling velocity at electron energies as low as a few *** results are discussed in the context of more complex geometries supporting multiple modes with spatial and spectral *** provide fundamental insights into spontaneous and stimulated electron-light-matter interactions with key implications for research on(quantum)coherent optical phenomena at the nanoscale.

关键词： photon quantum coupling

普通海洋物种作为保护界定目标的功能性价值:以沙管虫(Lanice conchilega[Pallas 1766],多毛纲,环节动物门)底床为例

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AMBIO－人类环境杂志 2008年第5期37卷 330-338页

作者： Laurent Godet nicolas Toupoint Frédéric Olivier jérme Fournier Christian Retière 赵绪才

海洋环境保护主要集中在对受到威胁的,更确切说对那些脆弱和濒危物种的保护,比如鸟类和哺乳动物。在处理海洋栖息地保护方面,科学界的兴趣主要放在多样性的热点地区,如欧洲的海草床,或具地方特有性的热点区域,如热带区域的珊瑚礁等。然... 详细信息

海洋环境保护主要集中在对受到威胁的,更确切说对那些脆弱和濒危物种的保护,比如鸟类和哺乳动物。在处理海洋栖息地保护方面,科学界的兴趣主要放在多样性的热点地区,如欧洲的海草床,或具地方特有性的热点区域,如热带区域的珊瑚礁等。然而,以普通的、分布广泛的海洋无脊椎动物沙管虫(Laniceconchilega,多毛纲蛰龙介科[Terebellidae])为例,我们展示了为保护目的而选择最佳的自然环境成分时,物种的脆弱性和稀有性并不是唯一要考虑的要素。这个物种能够形成增加生物多样性的致密海底床,是鸟类和鱼类有吸引力的摄食场所,并且具有较高的社会经济价值。因此,它们具有较高的功能性价值,应该看作是重要的保护界定目标。通过绍塞(Chausey)群岛和圣米歇尔山湾(Mont Saint-Michel)(法国)的实例,我们提出一个综合的学科间方法来评价这些海底床的保护需求。尽管它们有很高的遗产价值,考虑到这些自然要素和很多相同的要素还没有受益于欧洲任何法律上的保护,这个问题显得愈发紧迫了。

关键词：海洋环境保护社会经济价值濒危物种多毛纲环节动物门底床管虫界定

Crystal growth of bullet-shaped magnetite in magnetotactic bacteria of the Nitrospirae phylum

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Crystal growth of bullet-shaped magnetite in magnetotactic b...

Predictors of future stroke in adults 60-64 years living in the community

中国科学院地质与地球物理研究所2015年度（第15届）学术年会

作者： jinhua Li nicolas Menguy Christophe Gatel Victor Boureau Etienne Snoeck Gilles Patriarche Eric Leroy Yongxin Pan Paleomagnetism and Geochronology Lab Key Laboratory of Earth and Planetary PhysicsInstitute of Geology and Geophysics Chinese Academy of Sciences Institut de Mineralogie de Physique des Materiaux et de Cosmochimie (IMPMC) Sorbonne Universites—UPMC Univ Paris 06 UMR CNRS 7590 Museum National d’Histoire Naturelle (MNHN) IRD UMR 2064 Place Jussieu Paris 75005 France France-China Biomineralization and Nano-structures Laboratory Chinese Academy of Sciences CEMES/CNRS LPN-UPR20/CNRS Route de Nozay Marcoussis 91460 France

Magnetotactic bacteria(MTB) are known to produce single-domain magnetite or greigite crystals within intracellular membrane organelles and to navigate along the Earth’s magnetic field lines. MTB have been suggested as being one of the most ancient biomineralizing metabolisms on the Earth and they represent a fundamental model of intracellular biomineralization. Moreover, the determination of their specific crystallographic signature(e.g. structure and morphology) is essential for palaeoenvironmental and ancient-life studies. Yet, the mechanisms of MTB biomineralization remain poorly understood, although this process has been extensively studied in several cultured MTB strains in the Proteobacteria phylum. Here, we show a comprehensive transmission electron microscopy(TEM) study of magnetic and structural properties down to atomic scales on bullet-shaped magnetites produced by the uncultured strain MYR-1 belonging to the Nitrospirae phylum, a deeply branching phylogenetic MTB group. We observed a multiple-step crystal growth of MYR-1 magnetite: initial isotropic growth forming cubo-octahedral particles(less than approx. 40 nm), subsequent anisotropic growth and a systematic final elongation along [001] *** the crystal growth, one major f111 g face is well developed and preserved at the larger basal end of the crystal. The basal f111 g face appears to be terminated by a tetrahedral – octahedral-mixed iron surface, suggesting dimensional advantages for binding protein(s), which may template the crystallization of magnetite. This study offers new insights for understanding magnetite biomineralization within the Nitrospirae phylum.

关键词： magnetotactic bacteria Nitrospirae phylum bullet-shaped magnetite crystal growth biomineralization micromagnetic property

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World journal of Neurology 2016年第1期6卷 14-22页

作者： nicolas Cherbuin Leeanne Carey Moyra Mortby Kaarin j Anstey Centre for Research on Ageing Health and Wellbeing Australian National University Neurorehabilitation and Recovery Stroke Division the Florey Institute of Neuroscience and Mental Health Department of Occupational Therapy La Trobe University

AIM:To investigate predictors of incident stroke in a large epidemiological sample of cognitively healthy individuals in their early 60'***:Cardiovascular(systolic and diastolic blood pressure, hypertension status and medication, body mass index, lung forced vital capacity), lifestyle(alcohol intake, smoking, physical activity), mental health(anxiety and depression status, medication and symptomatology), cognition(executive function, processing speed, working memory, sensorimotor skills), and personality measures(behavioural inhibition and activation, positive and negative affect, neuroticism, psychoticism, extraversion) were investigated as predictors of incident stroke in 1774 participants from the Personality and Total Health Through Life Project over an 8-year *** regression analyses controlled for age, gender, and education were conducted in the whole cohort as well as in case-control subanalyses including precisely matched controls to identify factors associated with stroke ***:The cohort selected had a mean age of 62.5 years(SD = 1.5) and was 48.6% female with an average of 14.1 years of education(SD = 2.6).When 28 individuals with incident stroke were compared to 1746 cognitively healthy individuals in multivariate logistic regression analyses the only significant predictors of stroke across the five domains considered(cardiovascular, lifestyle, mental health, cognition, personality) and after controlling for gender, age, and education were systolic blood pressure(per unit above 140 mm Hg:OR = 1.04, 95%CI:1.01-1.07, P = 0.002), smoking(trend OR = 2.28, 95%CI:0.99-5.24, P = 0.052), and sensorimotor skills(purdue pegboard:OR = 0.80, 95%CI:0.62-0.96, P = 0.037).Similarly, in matched-control analyses significant group differences were found for systolic blood pressure(P = 0.001), smoking(P = 0.036), and sensorimotor skills(P = 0.028).CONCLUSION:Identified predictors of incident stroke in community-living individuals included hi

关键词： Smoking Fine motor skills Longitudinal Epidemiology Hypertension Cognition Personality Stroke

Targeting Kupffer cells in non-alcoholic fatty liver disease/non-alcoholic steatohepatitis: Why and how?

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World journal of Hepatology 2015年第19期7卷 2184-2188页

作者： nicolas Lanthier Service d’Hépato-gastroentérologie Cliniques Universitaires Saint-Luc Université catholique de Louvain Laboratory of Hepatogastroenterology Institut de Recherche Expérimentale et Clinique Université catholique de Louvain

Mechanisms for non-alcoholic steatohepatitis(NASH)development are under investigation in an era of increased prevalence of obesity and metabolic syndrome. Previous findings have pointed to the role of adipose tissue, adipose tissue macrophages and their secretory products in the development of a chronic inflammatory status inducing insulin resistance and a higher risk of liver steatosis called non-alcoholic fatty liver disease. The activation of resident macrophages [Kupffer cells(KC)] and the recruitment of blood derived monocytes/macrophages into the diseased liver have now been identified as key elements for disease initiation and progression. Those cells could be activated through gut flora modifications and an altered gut barrier function but also through the internalization of toxic lipid compounds in adjacent hepatocytes or in KC themselves. Due to the role of activated KC in insulin resistance, fibrosis development and inflammation amplification, they became a target in clinical trials. A shift towards an anti-inflammatory KC phenotype through peroxisome proliferator activator-receptorδ agonists, an inhibition of macrophage recruitment through anti-C-C chemokine receptor 2 action and a specific blocking of internalization of toxic lipoxidation or glycation compounds into KC by galectin-3 receptor inhibitors are now under investigation in human NASH.

关键词： Steatosis Non-alcoholic steatohepatitis Insulin No

Endoproteolytic cleavage as a molecular switch regulating and diversifying prion protein function

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Neural Regeneration Research 2016年第2期11卷 238-239页

作者： Cathryn L.Haigh Steven j.Collins Department of Medicine (Royal Melbourne Hospital) The University of Melbourne

The prion protein（Pr P）,through misfolding,is widely known for its causative role in prion diseases,which are transmissible neurodegenerative diseases of humans and *** is still no defined function assigned to Pr P,especially in the central nervous system,despite many studies in this *** functions are protean and include signal transduction,neuroprotection,neurogenesis,neuritogenesis,metal-ion homeostasis,memory formation and consolidation,as well as circadian rhythms（nicolas et al.,2009）.

关键词： molecular cleavage Endoproteolytic