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Negative supracrystals inducing a FCC-BCC transition in gold nanocrystal superlattices

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Nano Research 2014年第2期7卷 171-179页

作者： nicolas Goubet Universite Pierre et Marie Curie Paris 6 UMR 7070 LM2N BP 52 4 place Jussieu 75005 Paris France Centre National de la Recherche Scientifique Unite Mixte de Recherche 7070 LM2N 4 place Jussieu 75005 Paris France

The growth of nanocrystal superlattices of 5 nm single domain Au nanocrystals at an air-toluene interface induces formation of well-defined thin films （300--400 nm） with large coherence lengths. High-resolution electron microscopy showed that polyhedral holes （negative supracrystal） were formed on the nanocrystal superlattice surface. Formation of negative supracrystals is attributed to inclusion in the superlattice of organic molecules （dodecanethiol）, which are present in concentrated zones at the air-toluene interface. The coexistence of two supracrystalline structures （bcc/fcc） is attributed to diffusion of dodecanethiol molecules resulting in a Bain deformation of the nanocrystal array.

关键词： Negative crystalBain transformation nanocrystal superlattice supracrystal gold nanocrystal self-assembly

Performance Back-deduction from a Loading to Flow Coefficient Map:Application to Radial Turbine

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Journal of Thermal Science 2012年第6期21卷 509-517页

作者： Xavier CARBONNEAU nicolas BINDER Université de Toulouse Institut Supérieur de l'Aéronautique et de l'Espace(ISAE)10avenue Edouard Belin BP 54032 31400 ToulouseFrance

Radial turbine stages are often used for applications requiring off-design operation,as turbocharging for *** off-design ability of such stages is commonly analyzed through the traditional turbine map,plotting the reduced mass-flow against the pressure-ratio,for reduced-speed ***,some alternatives are possible,such as the flow-coefficient(Ψ)to loading-coefficient(φ)diagram where the pressure-ratio lines are actually straight lines,very convenient property to perform prediction.A robust method re-creating this map from a predicted Ψ-φ diagram is *** work has shown that this back-deduction quality,without the use of any loss models,depends on the knowledge of an intermediate pressure-ratio.A modelization of this parameter is then *** comparison with both experimental and CFD results is presented,with quite good agreement for mass flow rate and rotational speed,and for the intermediate pressure *** last part of the paper is dedicated to the application of the intermediate pressure-ratio knowledge to the improvement of the deduction of the pressure ratio lines in the Ψ-φ *** this improvement,the back-deduction method of the classical map is structured,applied and evaluated.

关键词： Radial turbine off-design flow coefficient load coefficient performance

Blockchain software patterns for the design of decentralized applications:A systematic literature review

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Blockchain(Research and Applications) 2022年第2期3卷 25-38页

作者： nicolas Six nicolas Herbaut Camille Salinesi Centre de Recherche en Informatique Universite Paris 1 Pantheon-Sorbonne75231 ParisFrance

A software pattern is a reusable solution to address a commonly occurring problem within a given context when designing *** patterns is a common practice for software architects to ensure software *** pattern collections have been proposed for a large number of application ***,because of the technology's recentness,there are only a few available collections with a lack of extensive testing in industrial blockchain *** is also difficult for software architects to adequately apply blockchain patterns in their applications,as it requires deep knowledge of blockchain *** a systematic literature review,this paper has identified 120 unique blockchain-related patterns and proposes a pattern taxonomy composed of multiple categories,built from the extracted pattern *** purpose of this collection is to map,classify,and describe all the available patterns across the literature to help readers make adequate decisions regarding blockchain pattern *** study also shows potential applications of those patterns and identifies the relationships between blockchain patterns and other non-blockchain software patterns.

关键词： Blockchain Software patterns Software design Smart contracts

Inspection of free energy functions in gradient crystal plasticity

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Acta Mechanica Sinica 2013年第6期29卷 763-772页

作者： Samuel Forest nicolas Guninchault Centre des Matriaux Mines ParisTechCNRS UMR 7633 BP 8791003 Evry CedexFrance

The dislocation density tensor computed as the cud of plastic distortion is regarded as a new constitutive variable in crystal plasticity. The dependence of the free energy function on the dislocation density tensor is explored starting from a quadratic ansatz. Rank one and logarithmic dependencies are then envisaged based on considerations from the statistical theory of dislocations. The rele- vance of the presented free energy potentials is evaluated from the corresponding analytical solutions of the periodic two-phase laminate problem under shear where one layer is a single crystal material undergoing single slip and the second one remains purely elastic.

关键词： Gradient plasticity Crystal plasticity Continuum thermodynamics Dislocation density tensor Read- Shockley energy

Detailed Analysis of the Flow in the Inducer of a Transonic Centrifugal Compressor

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Journal of Thermal Science 2012年第1期21卷 1-12页

作者： nicolas Buffaz Isabelle Trébinjac Laboratoire de Mécanique des Fluides et d'Acoustique Ecole Centrale de Lyon 36 av. Guy de Collongue

Numerical and experimental investigations were conducted in a transonic centrifugal compressor stage composed of a backswept splittered unshrouded impeller and a vaned diffuser. A detailed analysis of the flow in the inducer (i.e. the entry zone of the impeller between the main blade leading edge and the splitter blade leading edge) is proposed from choke to surge. Steady and unsteady simulations were performed using the code elsA, which uses a multi-domain approach on structured meshes and solves the compressible RANS equations, associated with a two-equation turbulence model k-l in the rotating frame of reference. The 1MW LMFA-ECL test rig was used for carrying out the tests in the compressor stage. Unsteady pressure measurements up to 150 kHz and Laser Doppler Anemometry measurements were performed in the inducer. A good agreement is obtained between the experimental and numerical data even if an over dissipation is noticed in the numerical results. The change in flow pattern from choke to surge is mainly due to a change in the tip leakage flow trajectory which straightens, leading to a flow blockage of an individual passage near shroud. A spectral analysis shows that only the blade passing frequency and its harmonics compose the various spectra obtained from choke to surge.

关键词： transonic centrifugal compressor inducer unsteady pressure measurements

Sensing of physiological regulators by innate lymphoid cells

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Cellular & Molecular Immunology 2019年第5期16卷 442-451页

作者： Cyril Seillet nicolas Jacquelot Molecular Immunology Division Walter and Eliza Hall Institute of Medical ResearchMelbourneVIC 3052Australia Department of Medical Biology University of MelbourneMelbourneVIC 3010Australia

Maintenance of homeostasis and immune protection rely on the coordinated action of different physiological *** communication between the immune system and physiological systems is required to sense and restore any disruption of *** transcriptomic analyses of innate lymphoid cells(ILCs)from different tissues have revealed that ILCs express a large array of receptors involved in the recognition of neuropeptides,hormones and metabolic *** rapidly secrete effector cytokines that are central in the development and activation of early immune responses,but they also constitutively secrete mediators that are important for tissue *** achieve these functions effectively,ILCs integrate intrinsic and extrinsic signals that modulate their constitutive and induced *** of the regulation of ILCs by physiological regulators leads to altered immune responses with harmful consequences for the *** understanding of these complex interactions between the immune system and physiological mediators is crucial to decipher the events leading to the protective versus pathological effects of these cells.

关键词： innate lymphoid cells immunity immune protection homeostasis

New animal models for hepatitis C viral infection and pathogenesis studies

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World Journal of Gastroenterology 2007年第17期13卷 2427-2435页

作者： Dina Kremsdorf nicolas Brezillon INSERM U812 ParisFrance Pasteur Institute Paris France Université Paris Descartes Faculté de Médecine René Descartes CHU Necker Paris 75015France

Hepatitis C virus （HCV） is a major cause of chronic liver disease, cirrhosis and hepatocellular carcinoma （HCC）. In man, the pathobiological changes associated with HCV infection have been attributed to both the immune system and direct viral cytopathic effects. Until now, the lack of simple culture systems to infect and propagate the virus has hampered progress in understanding the viral life cycle and pathogenesis of HCV infection, including the molecular mechanisms implicated in HCV-induced HCC. This clearly demonstrates the need to develop small animal models for the study of HCV-associated pathogenesis. This review describes and discusses the development of new HCV animal models to study viral infection and investigate the direct effects of viral protein expression on liver disease.

关键词： Hepatitis C virus Viral infection Transgenicmice Pathogenesis

Convex Concentration for Some Additive Functionals of Jump Stochastic Differential Equations

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Acta Mathematica Sinica,English Series 2013年第8期29卷 1449-1458页

作者： Yutao MA nicolas PRIVAULT School of Mathematical Sciences and Laboratory for Mathematics and Complex Systems Beijing Normal University School of Physical and Mathematical Sciences Nanyang Technological University

Using forward-backward stochastic calculus, we prove convex concentration inequalities for some additive functionals of the solution of stochastic differential equations with jumps admitting an invariant probability measure. As a consequence, transportation-information inequalities are obtained and bounds on option prices for interest rate derivatives are given as an application.

关键词： Convex concentration inequalities transportation-information inequalities stochastic differential equations with jumps interest rate derivatives

Impedance spectroscopy of the cell/nanovolcano interface enables optimization for electrophysiology

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Microsystems & Nanoengineering 2023年第3期9卷 297-308页

作者： nicolas Maïno Arnaud Bertsch Philippe Renaud Microsystems laboratory 4 Institute of Electrical and Micro EngineeringEcole Polytechique Fédérale de Lausanne(EPFL)LausanneSwitzerland

Volcano-shaped microelectrodes have demonstrated superior performance in measuring attenuated intracellular action potentials from cardiomyocyte cultures. However, their application to neuronal cultures has not yet yielded reliable intracellular access. This common pitfall supports a growing consensus in the field that nanostructures need to be pitched to the cell of interest to enable intracellular access. Accordingly, we present a new methodology that enables us to resolve the cell/probe interface noninvasively through impedance spectroscopy. This method measures changes in the seal resistance of single cells in a scalable manner to predict the quality of electrophysiological recordings. In particular, the impact of chemical functionalization and variation of the probe’s geometry can be quantitatively measured. We demonstrate this approach on human embryonic kidney cells and primary rodent neurons. Through systematic optimization, the seal resistance can be increased by as much as 20-fold with chemical functionalization, while different probe geometries demonstrated a lower impact. The method presented is therefore well suited to the study of cell coupling to probes designed for electrophysiology, and it is poised to contribute to elucidate the nature and mechanism of plasma membrane disruption by micro/nanostructures.

关键词： enable interface optimization