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Prospective associations between joint categories of physical activity and insomnia symptoms with onset of poor mental health in a population-based cohort

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Journal of Sport and Health Science 2023年第3期12卷 295-303页

作者： Mitch J Duncan Elizabeth G Holliday nicola w burton Nicholas Glozier Stina Oftedal School of Medicine and Public Health College of HealthMedicineand WellbeingThe University of NewcastleCallaghanNSW 2308Australia Priority Research Centre for Physical Activity and Nutrition The University of NewcastleCallaghanNSW 2308Australia School of Applied Psychology Griffith UniversityBrisbaneQLD 4122Australia Menzies Health Institute Queensland Griffith UniversityBrisbaneQLD 4122Australia Brain and Mind Centre Central Clinical SchoolThe University of SydneyNSW 2050Australia

Background:Physical inactivity and insomnia symptoms are independently associated with increased risk of depression and anxiety;however,few studies jointly examine these risk *** study aimed to prospectively examine the joint association of physical activity(PA)and insomnia symptoms with onset of poor mental health in ***:Participants from the 2013 to 2018 annnual waves of the Household Income and Labour Dynamics in Australia panel study who had good mental health(Mental Health Inventory-5>54)in 2013,and who completed at least 1 follow-up survey(2014-2018),were included(n=10,977).Poor mental health(Mental Health Inventory-5≤54)was assessed ***(2013)PA was classified as high/moderate/low,and insomnia symptoms(i.e.,trouble sleeping)were classified as no insomnia symptoms/insomnia symptoms,with 6 mutually exclusive PAinsomnia symptom groups *** of PA-insomnia symptom groups with onset of poor mental health were examined using discrete-time proportional-hazards logit-hazard ***:There were 2322 new cases of poor mental health(21.2%).Relative to the high PA/no insomnia symptoms group,there were higher odds(odds ratio and 95%confidence interval(95%CI))of poor mental health among the high PA/insomnia symptoms(OR=1.87,95%CI:1.57-2.23),moderate PA/insomnia symptoms(OR=1.93,95%CI:1.61-2.31),low PA/insomnia symptoms(OR=2.33,95%CI:1.96-2.78),and low PA/no insomnia symptoms(OR=1.14,95%CI:1.01-1.29)*** level of PA combined with insomnia symptoms was associated with increased odds of poor mental health,with the odds increasing as PA ***:The se findings highlight the potential benefit of interventions targeting both PA and insomnia symptoms for promoting mental health.

关键词： Depression Physical activity Sleep quality

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Factors associated with changes in physical activity and sedentary behaviour during one year among university-based young adults

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Sports Medicine and Health Science 2021年第4期3卷 236-242页

作者： Riaz Uddin nicola w.burton Asaduzzaman Khan School of Health and Rehabilitation Sciences The University of QueenslandAustralia Institute for Physical Activity and Nutrition(IPAN) School of Exercise and Nutrition ScienceDeakin UniversityAustralia School of Applied Psychology Griffith UniversityAustralia School of Human Movement and Nutrition Sciences The University of QueenslandAustralia

The purpose of this study was to identify correlates of changes in physical activity(PA)and sedentary behaviour(SB)among university-based young adults in *** were from a 1-year prospective study with 2 assessment points(baseline n=573,20.7±1.35 years,45%female;retention rate 69%,analytical sample=395).Participants completed a self-administered written survey on PA,SB,health and lifestyle be-haviours,and *** in PA were categorised as:negligible(±week),>60 min/week decrease,or>60 min/week *** in SB were categorised as negligible(±week),>120 min/week decrease,and>120 min/week *** logistic regression analysis was used to identify the *** quarters(72%)of participants had insufficient PA at both assessment *** those who were sufficiently active at wave 1,5%became insufficiently active at wave *** quarter of par-ticipants(23%)had high SB at wave 1 and wave *** those who had low SB at wave 1,16%had high SB at wave *** male[OR=2.04(95%CI:1.06–3.93)],baseline phone time of>2 h/day[OR=3.14(95%CI:1.04–7.04)]and not participating in organised sports at baseline[OR=2.56(95%CI:1.24–5.29)]were associated with a decrease in PA by>60 min/*** who frequently experienced stress at baseline had higher odds of increasing SB by>120 min/day[OR=1.83(95%CI:1.04–3.23)].SB is more variable than PA over 1 year in university-based young adults in ***,those with high phone time,those not engaging with organised sports,and those with frequent stress may change to a more inactive lifestyle.

关键词： Developing country Health behaviour Health promotion Longitudinal data South Asia University student

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High-intensity Interval Training for the Management of Nonalcoholic Steatohepatitis: Participant Experiences and Perspectives

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Journal of Clinical and Translational Hepatology 2023年第5期11卷 1050-1060页

作者： Shelley E.Keating Ilaria Croci Matthew P.wallen Emily R.Cox Jeff S.Coombes nicola w.burton Graeme A.Macdonald Ingrid J.Hickman Centre for Research on Exercise Physical Activity and HealthSchool of Human Movement and Nutrition SciencesThe University of QueenslandBrisbaneAustralia K.G.Jebsen Center of Exercise in Medicine Norwegian University of Science and Technology Department of Circulation and Medical ImagingFaculty of MedicineTrondheimNorway Department of Sport Exercise and HealthUniversity of BaselBaselSwitzerland Caring Futures Institute College of Nursing and Health SciencesFlinders UniversityAdelaideAustralia Institute of Health and wellbeing Federation UniversityMount HelenAustralia School of Environmental and Life Sciences University of NewcastleOurimbahAustralia School of Applied Psychology Griffith UniversityMt GravattAustralia Menzies Health Institute Griffith UniversityGold CoastAustralia Centre for Mental Health Griffith UniversityBrisbaneAustralia Department of Gastroenterology and Hepatology Princess Alexandra HospitalBrisbaneAustralia Faculty of Medicine The University of QueenslandBrisbaneAustralia Department of Nutrition and Dietetics Princess Alexandra HospitalBrisbaneAustralia

Background and Aims:High-intensity interval training(HIIT)is a therapeutic option for people with nonalcoholic steatohepatitis(NASH).However,the perspectives and experiences of HIIT for people with NASH are unknown,limiting translation of *** explored the experiences and perspectives of both professionally supervised and self-directed HIIT in people with NASH and evaluated participant-reported knowledge,barriers,and enablers to commencing and sustaining ***:Twelve participants with NASH underwent 12 weeks of supervised HIIT(3 days/week,4×4 minutes at 85–95%maximal heart rate,interspersed with 3 minutes active recovery),followed by 12-weeks of selfdirected(unsupervised)***-on-one,semistructured participant interviews were conducted by exercise staff prior to HIIT and following both supervised and self-directed HIIT to explore prior knowledge,barriers,enablers,and outcomes at each *** were audio-recorded,transcribed,coded,and thematically analyzed by two independent ***:Four dominant themes were identified:(1)no awareness of/experience with HIIT and ambivalence about exercise capabilities;(2)multiple medical and social barriers to commencing and continuing HIIT;(3)exercise specialist support was a highly valued enabler,and(4)HIIT was enjoyed and provided holistic ***:People with NASH may lack knowledge of and confidence for HIIT,and experience multiple complex barriers to commencing and continuing *** specialist support is a key enabler to sustained *** factors need to be addressed in future clinical programs to augment the uptake and long-term sustainability of HIIT by people with NASH so they can experience the range of related benefits.

关键词： Nonalcoholic fatty liver disease NAFLD Exercise Lifestyle Qualitative Patient-reported outcomes

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A pilot double-blind, randomized, placebo-controlled trial of curcumin/bioperine for lung cancer chemoprevention in patients with chronic obstructive pulmonary disease

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Advances in Lung Cancer 2013年第3期2卷 62-69页

作者： Amir Sharafkhaneh J. Jack Lee Diane Liu Ruth Katz Nancy Caraway Cherise Acosta Ignacio I. wistuba Bharat Aggarwal burton Dickey Seyed J. Moghaddam nicola Hanania Robert Newman Hanan Abdel-Monem Nga Bich Nguyen Carol J. Farhangfar waun K. Hong Jonathan M. Kurie Department of Biostatistics The University of Texas MD Anderson Cancer Center Houston USA Department of Experimental Therapeutics The University of Texas MD Anderson Cancer Center Houston USA Department of Medicine Baylor College of Medicine Houston USA Department of Pathology The University of Texas MD Anderson Cancer Center Houston USA Department of Pulmonary Medicine The University of Texas MD Anderson Cancer Center Houston USA Department of Thoracic/Head and Neck Medical Oncology The University of Texas MD Anderson Cancer Center Houston USA Division of Cancer Medicine The University of Texas MD Anderson Cancer Center Houston USA

Chronic obstructive pulmonary disease is an inflammatory condition with increased risk of lung cancer. we hypothesized that curcumin/ bioperine (CB), which has anti-inflammatory effects, may reduce cytological abnormalities in the sputum of patients with COPD. we conducted a 3-month, three-to-one randomized, doubleblind, pilot trial of escalating doses of CB in patients with moderate or worse COPD who were capable of producing sputum. The primary efficacy endpoint was changed in sputum cytology. we also explored changes in fluorescence in situ hybridization (FISH). we obtained sputum samples for cytology and chromosome abnormalities at baseline and each monthly follow-up visit. we enrolled 57 participants, with 35 completing the study. The participants’ mean age (standard deviation [SD]) was 66.6 (8.2) years, and they were mainly male (91.2%), with an average of 63.8 pack-years of smoking history. Also, 42.1% of participants were active smokers and the mean (SD) FEV1 was 37% (13%). At baseline, 13 subjects had moderate or worse dysplasia (22.8%). Subjects with moderate to severe sputum dysplasia had more chromosome abnormalities in epithelial cells and neutrophils, as measured by deletion and aneuploidy in 10q22.3. The changes in sputum cytology and chromosome abnormalities did not differ between the active and placebo arms. CB was well tolerated at the bid doses of 1, 1.5, and 2 gm of curcumin and 5 mg of bioperine, with minor side effects related to the gastrointestinal tract. In this short pilot trial, CB compared to placebo did not alter cytological and chromosomal abnormalities seen in sputum of patients with COPD.

关键词： Lung Cancer Inflammation Nutraceutical Agents COPD Cytological Abnormalities

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