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Resected specimen evaluation,anorectal manometry,endoanal ultrasonography and clinical follow-up after STARR procedures

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World Journal of Gastroenterology 2011年第19期17卷 2411-2416页

作者： Gabriele Naldini Guido Cerullo Claudia Menconi Jacopo Martellucci Simone Orlandi nicola romano Mauro Rossi Fourth Unit of Surgery Santa Chiara Hospital of Pisa Department of General Surgery University of Siena-Policlinico Le Scotte

AIM:To investigate stapled transanal rectal resection (STARR) procedures as surgical techniques for obstructed defecation syndrome (ODS) by analyzing specimen evaluation,anorectal manometry,endoanal ultrasonography and clinical follow-up.METHODS:From January to December 2007,we have treated 30 patients.Fifteen treated with double PPH-01 staplers and 15 treated using new CCS 30 contour.Resected specimen were measured with respect to average surface and volume.All patients have been evaluated at 24 mo with clinical examination,anorectal manometry and endoanal ultrasonography.RESULTS:Average surface in the CCS 30 group was 54.5 cm2 statistically different when compared to the STARR group (36.92 cm2).The average volume in the CCS 30 group was 29.8 cc,while in the PPH-01 it was23.8 cc and difference was statistically significant.The mean hospital stay in the CCS 30 group was 3.1 d,while in the PPH-01 group the median hospital stay was 3.4 d.As regards the long-term follow-up,an overall satisfactory rate of 83.3% (25/30) was achieved.Endoanal ultrasonography performed 1 year following surgery was considered normal in both of the studied groups.Mean resting pressure was higher than the preoperative value (67.2 mmHg in the STARR group and 65.7 mmHg in the CCS30 group vs 54.7 mmHg and 55.3 mmHg,respectively).Resting and squeezing pressures were lower in those patients not satisfied,but data are not statistically significant.CONCLUSION:The STARR procedure with two PPH-01 is a safe surgical procedure to correct ODS.The new Contour CCS 30 could help to increase the amount of the resected tissue without differences in early complications,post-operative pain and in hospital stay compared to the STARR with two PPH-01 technique.

关键词：临床检查直肠超声标本测压肛门评价程序

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Perinatal variation and covariation of oxidative status and telomere length in yellow-legged gull chicks

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Current Zoology 2019年第5期65卷 509-516页

作者： Marco PAROLINI Cristina Daniela POSSENTI Andrea romano Manuela CAPRIOLI Diego RUBOLINI nicola SAINO Department of Environmental Science and Policy University of MilanMilanItaly Department of Ecology and Evolution University of LausanneBuilding BiophoreLausanneSwitzerland

The perinatal period is critical to survival and performance of many organisms.In birds,rapid postnatal growth and sudden exposure to aerial oxygen around hatching markedly affect the chick redox status,with potentially negative consequences on physiology mediated by oxidative stress.In addition,telomere length(TL)undergoes reduction during birds’early life,partly depending on oxidative status.However,relatively few studies have focused specifically on the changes in oxidative status and TL that occur immediately after hatching.In this study of the yellow-legged gull Larus michahellis,we found that chicks undergo a marked increase in plasma total antioxidant capacity and a marked decrease in the concentration of pro-oxidant molecules during the first days after hatching.In addition,TL in erythrocytes decreased by 1 standard deviation over the 4days post-hatching.Body mass and tarsus length covaried with total antioxidant capacity and concentration of pro-oxidants in a complex way,that partly depended on sex and laying order,suggesting that oxidative status can affect growth.Moreover,TL positively covaried with the concentration of pro-oxidant molecules,possibly because retention of high concentrations of pro-oxidant molecules results from mechanisms of prevention of their negative effects,including reduction in TL.Thus,this study shows that chicks undergo marked variation in oxidative status,which predicts growth and subsequent TL,prompting for more studies of the perinatal changes in the critical posthatching stages.

关键词： early-life period oxidative status telomeres yellow-legged gull

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Predation risk affects egg mass but not egg steroid hormone concentrations in yellow-legged gulls

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Current Zoology 2019年第4期65卷 401-408页

作者： Cristina Daniela Possenti Alexandra Bea Bentz Andrea romano Marco Parolini Manuela Caprioli Diego Rubolini Kristen Navara nicola Saino Department of Environmental Science and Policy University of Milan Via Giovanni Celoria 26 Milano 20133 Italy Department of Agricultural and Environ mental Sciences Un iversity of Georgia 203 Poultry Science Building Athens GA 30602 USA

Predators have both direct, consumptive effects on their prey and non-lethal effects on physiology and behavior, including reproductive decisions, with cascading effects on prey ecology and evol tion. Here, we experime ntally tested such non-lethal effects of exposure to in creased predati on risk on clutch size, egg mass, and the concentration of yolk steroid hormones in the yellow-legged gull Larus michahellis. We simulated increased predation risk by displaying stuffed predators (adult fox Vulpes vulpes, and adult buzzard Buteo buteo) to breeding adults before egg laying. The concentration of corticosterone, which has bee n show n to in crease un der exposure to mater nal predati on risk in other species, and of testosterone did not differ between eggs from mothers exposed to the predators and eggs from control mothers (i.e., eggs exposed to a novel object of similar size and position to the stuffed predators). The concentration of the two hormones negatively covaried. Clutch size did not vary according to experimental treatment, whereas egg mass was markedly larger in clutches from n ests exposed to predators than in clutches from control n ests. By in creasing egg mass, mothers may reduce the risk of cooling of the eggs when incubation is impeded by predators, boost energy reserves, reduce post-natal detectability caused by food solicitation, and/ or enha nee developme nt at hatchi ng, thus increasing the cha nces of offspri ng survival. In general, our results are inconsistent with most of the few previous studies on similar non-lethal predator effects and suggest that such effects may vary among species according to ecological conditions, social behavior, and developmental mode.

关键词： clutch size corticosterone egg size predation effects testosterone

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Yolk vitamin E positively affects prenatal growth but not oxidative status in yellow-legged gull embryos

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Current Zoology 2018年第3期64卷 285-292页

作者： Marco PAROLINI Cristina Daniela POSSENTI Filiz KARADAS Graziano COLOMBO Maria romano Manuela CAPRIOLI Isabella DALLE-DONNE Diego RUBOLINI Aldo MILZANI nicola SAINO Department of Environmental Science and Policy University of Milan via Celoria 26 20133 Milano Italy Department of Animal Science University of Yuzuncu Yil 65090 Van Turkey Department of Biosciences University of Milan via Celoria 26 20133 Milan Italy

Parental effects occur whenever the phenotype of parents or the environment that they experience influences the phenotype and fitness of their offspring. In birds, parental effects are often mediated by the size and biochemical quality of the eggs in terms of maternally transferred components. Exogenous antioxidants are key egg components that accomplish crucial physiological functions during early life. Among these, vitamin E plays a vital role during prenatal development when the intense metabolism accompanying rapid embryo growth results in overproduction of pro-oxidant molecules. Studies of captive birds have demonstrated the positive effect of vitamin E supplementation on diverse phenotypic traits of hatchling and adult individuals, but its effects on embryo phenotype has never been investigated neither in captivity nor under a natural selection regime. In the present study, we experimentally tested the effect of the supplementation of vitamin E on morphological traits and oxidative status of yellow-legged gull () embryos. The supplementation of vitamin E promoted somatic growth in embryos soon before hatching, but did not affect their oxidative status. Our results suggest that maternally transferred vitamin E concentrations are optimized to prevent imbalances of oxidative status and the consequent raise of oxidative damage in yellow-legged gull embryos during prenatal development.

关键词：胚胎生长维生素非氧化欺骗蛋黄抗氧化剂人工孵化生物化学

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Quality of bowel preparation in patients with inflammatory bowel disease undergoing colonoscopy:What factors to consider?

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World Journal of Gastrointestinal Endoscopy 2023年第3期15卷 133-145页

作者： Antonietta Gerarda Gravina Raffaele Pellegrino Mario Romeo Giovanna Palladino Marina Cipullo Giorgia Iadanza Simone Olivieri Giuseppe Zagaria nicola De Gennaro Antonio Santonastaso Marco romano Alessandro Federico Department of Precision Medicine University of Campania"Luigi Vanvitelli"Naples 80138Italy

An adequate bowel preparation in patients with inflammatory bowel disease(IBD)is a prerequisite for successful colonoscopy for screening,diagnosis,and surveillance.Several bowel preparation formulations are available,both high-and low-volume based on polyethylene glycol.Generally,low-volume formulations are also based on several compounds such as magnesium citrate preparations with sodium picosulphate,oral sulphate solution,and oral sodium phosphatebased solutions.Targeted studies on the quality of bowel preparation prior to colonoscopy in the IBD population are still required,with current evidence from existing studies being inconclusive.New frontiers are also moving towards the use of alternatives to anterograde ones,using preparations based on retrograde colonic lavage.

关键词： Bowel preparation Colonoscopy Inflammatory bowel disease Crohn’s disease Ulcerative colitis Artificial intelligence

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Archeological crop marks identified from Cosmo-SkyMed time series: the case of Han-Wei capital city, Luoyang, China

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International Journal of Digital Earth 2017年第8期10卷 846-860页

作者： Aihui Jiang Fulong Chen nicola Masini Luigi Capozzoli Gerardo romano Maria Sileo Ruixia Yang Panpan Tang Panpan Chen Rosa Lasaponara Guolin Liu College of Geodesy and Geomatics Shangdong University of Science and TechnologyQingdaoPeople’s Republic of China Key Laboratory of Digital Earth Science Institute of Remote Sensing and Digital EarthChinese Academy of SciencesHaidian DistrictBeijingPeople’s Republic of China International Centre on Space Technologies for Natural and Cultural Heritage under the Auspices of UNESCO BeijingPeople’s Republic of China Institute for Archaeological and Monumental Heritage National Research CouncilTito ScaloItaly Institute of Methodologies for Environmental Analysis National Research CouncilTito ScaloItaly Department of Earth and Geoenvironmental Sciences University of Bari Aldo MoroBariItaly Zhengzhou Base International Center on Space Technologies for Natural and Cultural Heritage under the Auspices of UNESCOZhengzhouPeople’s Republic of China

The development of spaceborne Synthetic Aperture Radar(SAR)technology declares that the golden era of SAR remote sensing in archeology is approaching;however,nowadays its methodology framework is still lacking due to the inadequate case studies validated by ground-truths.In this study,we investigated the crop marks using multi-temporal Cosmo-SkyMed data acquired in 2013 by applying a twostep decision-tree classifier in conjunction with a spatial analysis in an area of archeological interest nearby the archeological site of Han-Wei capital city(1900–1500 BP),in Luoyang,China.The time-series backscattering anomalies related to the wheat growth cycle were identified and then further validated in two zones by geophysical investigations(Ground Penetration Radar and electrical measurements)and in a third zone by archeological excavations made after the SAR data acquisition.This study provides a new approach for the relic detection,shallowly buried and covered by the crop vegetation,by temporal crop marks on spaceborne SAR images.We also emphasize the necessity to establish a satellite-to-ground methodology framework for the promotion of remote-sensing technology in archeology.

关键词： SAR crop mark archeological prospection Luoyang HanWei capital city geoarcheology

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“世博会大门见”

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建筑实践 2015年第7期 24-27页

作者：徐会玲 Filippo romano

项目名称:米兰世博会大门地址:意大利,米兰建筑设计:Alessandro Scandurra-Scandurra Studio Architettura设计团队:Alessandro Scandurra,nicola Bianchi,Davide Sala,Giovanni Nardin Poe Matteo George结构:Redesco s.r.I.装置:Copra... 详细信息

关键词：世博会建筑师米兰大教堂建筑设计

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