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Supervised vs home-based exercise program in kidney transplant recipients: A pilot pragmatic non-randomized study

World Journal of Transplantation 2024年第4期14卷 123-132页

作者： Anna Crepaldi Giovanni Piva nicola Lamberti Michele Felisatti Luca Pomidori Yuri Battaglia Fabio Manfredini Alda Storari Pablo Jesús López-Soto Unit of Nephrology University Hospital of FerraraFerrara 44121Emilia-RomagnaItaly Department of Nursing Instituto Maimónides de Investigación Biomédica de CórdobaCordoba 14004AndalusiaSpain Department of Neuroscience and Rehabilitation University of FerraraFerrara 44121Emilia-RomagnaItaly Esercizio Vita Medical Fitness Ferrara 44124Emilia-RomagnaItaly Department of Medicine University of VeronaVerona 37100VenetoItaly Department of Nursing Maimonides Biomedical Research Institute of CordobaUniversity of CordobaReina Sofía University HospitalCordoba 14004AndalusiaSpain

BACKGROUND Although the benefits of exercise for kidney transplant recipients(KTRs)have been widely demonstrated,these patients experience several barriers in undertaking a structured exercise program in hospital and non-hospital *** To compare the effects of a supervised moderate-intensity gym-based intervention with a home-based low-intensity walking program on exercise capacity in *** KTRs were asked to choose between two six-month *** first group performed a low-intensity interval walking intervention at home-based exercise intervention (HBex). The second group performed a supervised training program at an adapted physical activitygym (Sgym), including aerobic and resistance training. The outcomes, collected at baseline and at the end of theprograms, included the 6-minute walking test, the peak oxygen consumption (VO_(2)peak) during a treadmill test,the 5-time sit-to-stand test, and blood *** patients agreed to participate and self-selected into the HBex (n = 9) and Sgym (n = 8) groups. Twopatients in the Sgym group dropped out because of familial problems. At baseline, patients in the HBex group weresignificantly older and had lower walking distance, VO_(2)peak, and lower limb strength. Primary outcome changeswere significantly greater in the HBex group than in the Sgym group (52 ± 23 m vs 8 ± 34;P = 0.005). No othersignificant differences between groups were observed. Both groups improved most of the outcomes in the withingroupcomparisons, with significant variations in VO_(2) ***-month moderate-intensity supervised or low-intensity home-based training programs effectively improvedexercise capacity in KTRs. Gym-based programs combine aerobic and resistance training;however, in-homewalking may be proposed for frail KTRs.

关键词： Exercise Transplantation Walking Training Nephrology Kidney disease

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逍遥散加味联合曲安奈德治疗口腔扁平苔藓肝郁血瘀证疗效研究

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陕西中医 2024年第7期45卷 918-921页

作者：卓思源 [澳大利亚]nicola Cirillo 杨小如何昕安徽中医药大学第一附属医院安徽合肥230031 墨尔本大学口腔健康学院墨尔本3000 山南市人民医院西藏山南856000 安徽医科大学附属口腔医院安徽合肥230036

目的:探讨逍遥散加味联合曲安奈德治疗口腔扁平苔藓(OLP)肝郁血瘀证的疗效及对唾液炎症因子的影响。方法:选取84例OLP肝郁血瘀证患者按照随机数字表法分为观察组(n=42)和对照组(n=42)。对照组予曲安奈德注射液1 ml混合等量2%盐酸利多卡... 详细信息

目的:探讨逍遥散加味联合曲安奈德治疗口腔扁平苔藓(OLP)肝郁血瘀证的疗效及对唾液炎症因子的影响。方法:选取84例OLP肝郁血瘀证患者按照随机数字表法分为观察组(n=42)和对照组(n=42)。对照组予曲安奈德注射液1 ml混合等量2%盐酸利多卡因注射液于病损边缘局部注射,观察组在对照组治疗基础上予以逍遥散加味治疗,治疗8周后比较两组的临床疗效、症状评分、唾液炎症因子、免疫功能及不良反应发生情况,记录治疗后6个月的复发情况。结果:观察组临床总有效率为92.86%高于对照组的76.19%(P0.05)。观察组复发率明显低于对照组(P<0.05)。结论:逍遥散加味联合曲安奈德可有效提高OLP肝郁血瘀证患者的治疗效果,进一步缓解患者的临床症状,降低复发率及唾液炎症因子表达水平,提高机体免疫功能,安全性较好。

关键词：口腔扁平苔藓肝郁血瘀逍遥散加味曲安奈德唾液炎症因子免疫功能不良反应

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万物皆AI?那自行车运动呢?

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中国自行车 2024年第4期 96-99页

作者：尼古拉·史密斯不详

在万物皆可AI(人工智能)的当下,能利用AI的力量来改善自行车运动吗?AI可以快速处理大量数据来探寻变化趋势,能在一定程度上预测未来,并且它正在渗透到我们生活的各个领域,自行车运动也避免不了它的进入。自行车运动员或者爱好者可以利... 详细信息

在万物皆可AI(人工智能)的当下,能利用AI的力量来改善自行车运动吗?AI可以快速处理大量数据来探寻变化趋势,能在一定程度上预测未来,并且它正在渗透到我们生活的各个领域,自行车运动也避免不了它的进入。自行车运动员或者爱好者可以利用这一新兴技术来提高他们的表现,享受更加舒适的骑行,或者只是为了让骑行更安全,你已经在不知不觉中应用到了AI技术。

关键词：自行车运动人工智能 AI技术快速处理新兴技术骑行预测未来万物

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福田中学校园设计

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建筑实践 2024年第4期 100-103页

作者：陈忱 nicola Saladino 吕守拓 Federico Ruberto reMIX临界工作室

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紧迫感增强欧洲车企加强合作

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商业周刊（中文版） 2024年第3期 54-55页

作者： Albertina Torsoli Stefan nicola Monica Raymunt 孟洁冰(译) 不详

大众汽车公司(Volkswagen)、雷诺公司(Renault)和斯泰54兰蒂斯集团(Stellantis)正在考虑采取不可思议的举措,不惜与势不两立的竞争对手结盟,以生产更便宜的电动汽车,抵御事关生存的威胁。

关键词：大众汽车公司电动汽车 Volkswagen 竞争对手紧迫感不可思议

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Empirical assessment of the role of the Sun in climate change using balanced multi-proxy solar records

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Geoscience Frontiers 2023年第6期14卷 191-209页

作者： nicola Scafetta Department of Earth Sciences Environment and GeoresourcesUniversity of Naples Federico IIComplesso Universitario di Monte S.Angelovia Cinthia21Naples 80126Italy

The role of the Sun in climate change is hotly *** studies suggest its impact is significant,while others suggest it is *** Intergovernmental Panel on Climate Change(IPCC)supports the latter view and suggests that nearly 100%of the observed surface warming from 1850–1900 to 2020 is due to anthropogenic ***,the IPCC’s conclusions are based solely on computer simulations made with global climate models(GCMs)forced with a total solar irradiance(TSI)record showing a low multi-decadal and secular *** same models also assume that the Sun affects the climate system only through radiative forcing–such as TSI–even though the climate could also be affected by other solar *** this paper I propose three“balanced”multi-proxy models of total solar activity(TSA)that consider all main solar proxies proposed in scientific *** optimal signature on global and sea surface temperature records is assessed together with those produced by the anthropogenic and volcanic radiative forcing functions adopted by the CMIP6 *** is done by using a basic energy balance model calibrated with a differential multi-linear regression methodology,which allows the climate system to respond to the solar input differently than to radiative forcings alone,and to evaluate the climate’s characteristic time-response as *** proposed methodology reproduces the results of the CMIP6 GCMs when their original forcing functions are applied under similar physical conditions,indicating that,in such a scenario,the likely range of the equilibrium climate sensitivity(ECS)could be 1.4℃to 2.8℃,with a mean of 2.1℃(using the HadCRUT5 temperature record),which is compatible with the low-ECS CMIP6 GCM ***,if the proposed solar records are used as TSA proxies and the climatic sensitivity to them is allowed to differ from the climatic sensitivity to radiative forcings,a much greater solar impact on climate change is found,along with a significant

关键词： Solar activity changes Solar variability climatic impact Global climate change and modeling Equilibrium climate sensitivity

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Effect of template shape on metal nanoimprinting:a dislocation dynamics study

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2010年第10期11卷 722-726页

作者： Lucia nicola Department of Materials Science and Engineering Delft University of Technology

Dislocation dynamics simulations are performed to investigate the effect of template shape on the nanoimprinting of metal layers. To this end, metal thin films are imprinted by a rigid template made of an array of equispaced indenters of various shapes, i.e., rectangular, wedge, and circular. The geometry of the indenters is chosen such that the contact area is approximately the same at the final imprinting depth. Results show that, for all template shapes, the final patterns strongly depend on the dislocation activity, and that each imprint differs from the neighboring ones. Large material pile ups appear between the imprints, such that polishing of the metal layer is suggested for application of the patterns in electronics. Rectangular indenters require the lowest imprinting force and achieve the deepest retained imprints.

关键词： Nanoimprinting Dislocation dynamics Simulations

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核能在净零世界中的作用

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世界科学 2024年第5期 22-25页

作者：李威尼古拉·琼斯

在能源不断摆脱化石燃料的过程中，核能是不是扮演了一个不可或缺的角色？在相关争议愈演愈烈的同时，新技术和体积更小的反应堆或许会打破这种平衡。在超安全核能公司发布的一段动画模拟了海啸摧毁核电站并切断未来城市电力供应的场景...

在能源不断摆脱化石燃料的过程中，核能是不是扮演了一个不可或缺的角色？在相关争议愈演愈烈的同时，新技术和体积更小的反应堆或许会打破这种平衡。在超安全核能公司发布的一段动画模拟了海啸摧毁核电站并切断未来城市电力供应的场景。接下去会发生什么？也没什么：核反应堆会安静地自行关闭。这段令人颇感安慰的视频说：“它就在那儿，慢慢地冷却，最后没有任何工作的部分，也没有任何液体，没有任何指令、操作。那个时候，我们设计的核反应堆本质上极为安全，能够抵御任何意外事件。”

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Production of metallic iron nanoparticles in a baffled stirred tank reactor: Optimization via computational fluid dynamics simulation

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Particuology 2020年第5期18卷 83-96页

作者： Giorgio Vilardi nicola Verdone Sapienza University of Rome Department of Chemical Engineering Materials EnvironmentVia Eudossiana 1800184RomeItaly

The aim of this work is to optimize iron nanoparticle production in stirred tank reactors equipped with two classical impellers:Rushton and four-pitched blade turbines,which are largely used in batch industrial synthesis and efficient *** main operative parameters of nanoparticle synthesis are the precursor initial concentration,reducing agent/precursor molar ratio,impeller-tank clearance,and impeller rotational *** parameters were varied during the synthesis to find the optimal operating values based on the Fe(0)(%)production,zeta potential,particle size distribution,and powder X-ray diffraction pattern *** found that the optimal operating conditions for nanoparticle production were an impeller velocity of 1500 rpm,initial iron precursor concentration of 20 mM,molar ratio of reducing agent to iron precursor of 3 mol/mol,and impeller clearance of 0.25 and 0.4 times the vessel diameter for Rushton and four-pitched blade impellers,*** these conditions achieved a total conversion of 0.94-0.98 and yielded a product with a unimodal size distribution and average diameters in the range 30-50 *** computational fluid dynamics results agreed with the expectations,and the obtained mixing Damkohler numbers show that the process is mixed controlled.

关键词： Nano zero-valent iron Computational fluid dynamics Turbulence Micromixing Length scale

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Integrating acupuncture:are there positive health outcomes for women?

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2017年第3期18卷 233-238页

作者： nicola ROBINSON School of Health and Social Care London South Bank University London SE10AA UK

The key health issues for women tend to be primarily associated with the female reproductive system. There are also other gender priorities and consequences associated with ageing, which require effective interventions. Acupuncture is used worldwide and its evidence base is increasing on both mechanisms of action and its effectiveness in clinical care. Although acupuncture may be a valuable addition to healthcare for some conditions, it is rarely fully integrated into mainstream Western medicine clinical practice. Inadequate design and poor reporting of clinical trials have been barriers. Additionally systematic reviews and meta-analyses have tended to be equivocal and have reported that there is insufficient evidence for its recommendation. Future research should focus on ensuring good trial design including cost effectiveness and qualitative data and using a more pragmatic stance which reflects acupuncture in clinical practice. Undoubtedly, effective interventions are always needed to ensure the best health outcomes and address preventable deaths, morbidities, and disabilities among women but integration will be compromised unless underpinned by good evidence.

关键词： Acupuncture Women's health Evidence-based medicine Acupuncture mechanisms of action Integration Health outcomes

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