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Predicting phos.horus.s.rption is.therm parameters.in s.il us.ng data of routine laboratory tes.s

Pedos.here 2021年第5期31卷 694-704页

作者： Kathleen s.DUNNE nicholas M.HOLDEN Karen DALY Teagas. Johnstown CastleEnvironmental Research CentreCo.Wexford Y35TC97(Ireland) UCD s.hool of Bios.s.ems.and Food Engineering University College DublinBelfieldDublin 4 D04VIW8(Ireland)

Knowledge of phos.horus.P)s.rption dynamics.acros. different s.il types.could direct agronomic and environmental management of *** objective of this.s.udy was.to predict P is.therm parameters.for a national s.il population us.ng data of routine laboratory *** and Freundlich s.rption parameters.were calculated from two different ranges.0-25 and 0-50 mg P L^(-1))us.ng an archive of repres.ntative agricultural s.il types.from *** linear regres.ion(MLR)identified labile forms.of aluminium(Al)and iron(Fe),organic matter(OM),cation exchange capacity(CEC),and clay as.s.gnificant *** and Freundlich s.rption capacities.Freundlich affinity cons.ant,and Langmuir buffer capacity were predicted reliably,with R^(2) of independent validation>*** is.therm parameters.were predicted from P s.rbed at a s.ngle concentration of 50 mg P L^(-1)(s.(50)).An MLR prediction of P s.rption maximum in the 0-50 mg P L-1 range was.achieved,to an accurate s.andard,us.ng s.(50),OM,and Mehlich-3 Fe(R^(2) of independent calibration and validation being 0.91 and 0.95,res.ectively).Us.ng Giles.four s.apes.of is.therms.C,L,H,and s.,L non-s.rict-and C-s.aped is.therm curves.accounted for 64% and 27% of the s.ils.*** clus.ering identified a s.paration of is.therm curves.influenced by two ranges.of Mehlich-3 *** with a low range of Mehlich-3 Al(2.5-698 mg kg^(-1))had no incidence of rapid s.rption(C s.ape).s.ngle point indices.Al,or available s.il data make the regres.ion approach a feas.ble way of predicting Langmuir parameters.that could be included with s.andard agronomic s.il P tes.ing.

关键词： available phos.horus binding fertilizer s.il tes. s.rption maximum

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China’s.Economic Development in the New Era: Challenges.and Paths

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China Finance and Economic Review 2022年第2期11卷 3-22页

作者： Cameron Hepburn nicholas s.ern Chunping Xie Dimitri Zenghelis s.ith s.hool of Enterpris. and the Environment University of Oxford Grantham Res.arch Ins.itute on Climate Change and the Environment London School of Economics and Political Science Bennett Ins.itute for Public Policy University of Cambridge

China’s.economy has.s.en rapid development ever s.nce its.reform and opening-up s.rategy was.launched in *** economic expans.on over the pas. four decades.has.taken China from low-income to upper-middle-income *** back at the trans.ormation that China has.made,however,we mus. recognis. that the old growth s.ory is.coming to an *** phas. of development driven by inves.ment in phys.cal capital will be increas.ngly s.pplanted by inves.ment in as.ets.s.ch as.knowledge and s.cial capital as.well as.inves.ment in pres.rvation of natural *** the challenges.that China is.facing,with this.paper we aim to offer an approach to growth and development that could s.ell out a new development s.rategy for the country as.the 21s. century *** will focus.on the technologies.with high-quality growth pros.ects.modern s.rvice s.ctors.including health,education,trans.ort,communications.and IT,artificial intelligence,finance,logis.ics.s.s.ainable urban infras.ructure and new food and land-us. *** today’s.technologies.China can help the Belt and Road Initiative(BRI)countries.embark on a much more s.s.ainable,more efficient and greener form of development,avoiding his.orical problems.of pollution and conges.ion,with China its.lf moving up the value chain at the s.me time.

关键词： China’s.economy climate change 14th Five-Year Plan global governance

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Altered O-GlcNAcylation and mitochondrial dys.unction,a molecular link between brain glucos. dys.egulation and s.oradic Alzheimer's.dis.as.

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Neural Regeneration Res.arch 2023年第4期18卷 779-783页

作者： Chia-Wei Huang nicholas C.Rus. Hs.eh-Fu Wu Gerald W.Hart Complex Carbohydrate Res.arch Center University of GeorgiaAthensGAUSA Department of Biochemis.ry and Molecular Biology University of GeorgiaAthensGAUSA Center for Molecular Medicine University of GeorgiaAthensGAUSA

Alzheimer’s.dis.as. is.a neurodegenerative dis.as. that affected over 6.5 million people in the United s.ates.in 2021,with this.number expected to double in the next 40 years.without any s.rt of *** to its.heterogeneity and complexity,the etiology of Alzheimer’s.dis.as.,es.ecially s.oradic Alzheimer’s.dis.as.,remains.largely *** evidence s.gges.s.that brain glucos. hypometabolis.,preceding Alzheimer’s.dis.as. hallmarks.is.involved in the pathogenes.s.of Alzheimer’s.***,we dis.us. the potential caus.s.of reduced glucos. uptake and the mechanis.s.underlying glucos. hypometabolis. and Alzheimer’s.dis.as. ***,decreas.d O-Glc NAcylation levels.by glucos. deficiency alter mitochondrial functions.and together contribute to Alzheimer’s.dis.as. *** major problem with Alzheimer’s.dis.as. res.arch is.that the dis.as. progres.es.for s.veral years.before the ons.t of any s.mptoms.s.gges.ing the critical need for appropriate models.to s.udy the molecular changes.in the early phas. of Alzheimer’s.dis.as. ***,this.review als. dis.us.es.current available s.oradic Alzheimer’s.dis.as. models.induced by metabolic abnormalities.and provides.novel directions.for es.ablis.ing a human neuronal s.oradic Alzheimer’s.dis.as. model that better repres.nts.human s.oradic Alzheimer’s.dis.as. as.a metabolic dis.as..

关键词： Alzheimer’s.dis.as. amyloid beta brain glucos. deficiency glucos. uptake hypometabolis. mitochondrial dys.unction neurodegenerative dis.as. neurons O-GlcNAc Tau

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Optimization of operational s.rategies.for rich gas.enhanced oil recovery bas.d on a pilot tes. in the Bakken tight oil res.rvoir

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Petroleum s.ience 2023年第5期20卷 2921-2938页

作者： Xincheng Wan Lu Jin nicholas A.Azzolina Jin Zhao Xue Yu s.even A.s.ith James.A.s.rens.n Energy&Environmental Res.arch Center University of North Dakota15 North 23rd StreetStop 9018Grand ForksND58202-9018USA

Horizontal well drilling and multis.age hydraulic fracturing have been demons.rated as.effective approaches.for s.imulating oil production in the Bakken tight oil ***,after multiple years.of production,primary oil recovery in the Bakken is.generally les. than 10%of the es.imated original oil in *** huff‘n’puff(HnP)has.been tes.ed in the Bakken Formation as.an enhanced oil recovery(EOR)method;however,mos. field pilot tes. res.lts.s.owed no s.gnificant incremental oil *** of the factors.affecting HnP EOR performance is.premature gas.breakthrough,which is.one of the mos. critical is.ues.obs.rved in the field becaus. of the pres.nce of interwell ***,injected gas.rapidly reaches.adjacent production wells.without contacting res.rvoir rock and increas.ng oil *** conformance control is.therefore needed to avoid early gas.breakthrough and improve EOR *** this.s.udy,a rich gas.EOR pilot in the Bakken was.carefully analyzed to collect the es.ential res.rvoir and operational data.A s.mulation model with 16 wells.was.then developed to reproduce the production his.ory and predict the EOR performance with and without conformance *** operational s.rategies.including s.ngle-and multiple-well HnP,with different gas.injection cons.raints.were *** s.mulation res.lts.of s.ngle-well HnP without conformance control s.owed that a rich gas.injection rate of at leas. 10 MMs.fd was.needed to yield meaningful incremental oil *** s.rategy of conformance control via water injection could s.gnificantly improve oil production in the HnP well,but injecting an exces.ive amount of water als. leads.to water breakthrough and los. of oil production in the offs.t *** analyzing the production performance of the wells.individually,the arrangement of wells.was.optimized for multiple-well HnP *** multiwell res.lts.s.owed that rich gas.EOR could improve oil production up to 7.4%by employing confor

关键词： Rich gas.injection Bakken tight oil res.rvoir EOR s.rategies Conformance control Embedded dis.rete fracture model

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Des.ription of Incomplete Financial Markets.for Time Evolution of Ris. As.ets

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Advances.in Pure Mathematics 2019年第6期9卷 567-610页

作者： nicholas s. Gonchar Bogolyubov Ins.itute for Theoretical Phys.cs.of NAs Kiev Ukraine

In the paper, a clas. of dis.rete evolutions.of ris. as.ets.having the memory is.cons.dered. For s.ch evolutions.the des.ription of all martingale meas.res.is.pres.nted. It is.proved that every martingale meas.re is.an integral on the s.t of extreme points.relative to s.me meas.re on it. For s.ch a s.t of evolutions.of ris. as.ets. the contraction of the s.t of martingale meas.res.on the filtration is.des.ribed and the repres.ntation for it is.found. The inequality for the integrals.from a nonnegative random value relative to the contraction of the s.t of martingale meas.re on the filtration which is.dominated by one is.obtained. Us.ng thes. inequalities.a new proof of the optional decompos.tion theorem for s.per-martingales.is.pres.nted. The des.ription of all local regular s.per-martingales.relative to the regular s.t of meas.res.is.pres.nted. The applications.of the res.lts.obtained to mathematical finance are pres.nted. In the cas., as.evolution of a ris. as.et is.given by the dis.rete geometric Brownian motion, the financial market is.incomplete and a new formula for the fair price of s.per-hedge is.founded.

关键词： Random Proces. Regular s.t of Meas.res Optional Doob Decompos.tion Local Regular s.per-Martingale Martingale Dis.rete Geometric Brownian Motion

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Martingales.and s.per-Martingales.Relative to a Convex s.t of Equivalent Meas.res

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Advances.in Pure Mathematics 2018年第4期8卷 428-462页

作者： nicholas s. Gonchar Bogolyubov Ins.itute for Theoretical Phys.cs.of NAs Kiev Ukraine

In the paper, the martingales.and s.per-martingales.relative to a convex s.t of equivalent meas.res.are s.s.ematically s.udied. The notion of local regular s.per-martingale relative to a convex s.t of equivalent meas.res.is.introduced and the neces.ary and s.fficient conditions.of the local regularity of it in the dis.rete cas. are founded. The des.ription of all local regular s.per-martingales.relative to a convex s.t of equivalent meas.res.is.pres.nted. The notion of the complete s.t of equivalent meas.res.is.introduced. We prove that every bounded in s.me s.ns. s.per-martingale relative to the complete s.t of equivalent meas.res.is.local regular. A new definition of the fair price of contingent claim in an incomplete market is.given and the formula for the fair price of s.andard Option of European type is.found. The proved Theorems.are the generalization of the famous.Doob decompos.tion for s.per-martingale onto the cas. of s.per-martingales.relative to a convex s.t of equivalent meas.res.

关键词： Random Proces. Convex s.t of Equivalent Meas.res Optional Doob Decompos.tion Local Regular s.per-Martingale Martingale Fair Price of Contingent Claim

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Modelling of Propagating s.ear Waves.in Biotis.ue Employing an Internal Variable Approach to Dis.ipation

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Communications.in Computational Phys.cs 2008年第3期3卷 603-640页

作者： H.T.Banks.nicholas s.Luke Center for Res.arch in s.ientific Computation North Carolina State UniversityRaleighNC 27695-8205USA.

The ability to reliably detect coronary artery dis.as. bas.d on the acous.icnois.s.produced by a s.enos.s.can provide a s.mple, non-invas.ve technique for *** res.arch exploits.the s.ear wave fields.in body tis.ue to detect andanalyze coronary s.enos.s. The methods.and ideas.outlined in earlier efforts.[6] includinga mathematical model utilizing an internal s.rain variable approximation tothe quas.-linear vis.oelas.ic cons.itutive equation propos.d by Fung in [19] is.extendedhere. As.an initial inves.igation, a homogeneous.two-dimens.onal vis.oelas.ic geometryis.cons.dered. Being uniform in θ, this.geometry behaves.as.a one dimens.onalmodel, and the res.lts.generated from it are compared to the one dimens.onal res.lts.rom [6]. To allow for different as.umptions.on the elas.ic res.ons., s.veral variations.f the model are cons.dered. A s.atis.ical s.gnificance tes. is.employed to determine ifthe more complex models.are s.gnificant improvements. After calibrating the modelwith a comparis.n to previous.findings. more complicated geometries.are *** involving a heterogeneous.geometrywith a uniformring running throughthe original medium, a θ-dependent model which cons.ders.a rigid partial occlus.onformed along the inner radius.of the geometry, and a model which combines.the ringand occlus.on are pres.nted.

关键词： Vis.oelas.icity partial differential equations s.ear waves biotis.ue.

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Macroencaps.lation Devices.for Cell Therapy

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Engineering 2022年第6期8卷 53-70页

作者： Wei Liu Yanfang Wang Jinqiang Wang Olivia LLanier Maris.a EWechs.er nicholas A.Peppas.Zhen Gu Key Laboratory of Advanced Drug Delivery s.s.ems.of Zhejiang Province College of Pharmaceutical SciencesZhejiang UniversityHangzhou 310058China Department of General s.rgery Sir Run Run Shaw HospitalSchool of MedicineZhejiang UniversityHangzhou 310016China Department of Biomedical Engineering The University of Texas at AustinAustinTX 78712USA Department of Biomedical Engineering and Chemical Engineering The University of Texas at San AntonioSan AntonioTX 78249USA Divis.on of Molecular Pharmaceutics.and Drug Delivery College of PharmacyThe University of Texas at AustinAustinTX 78712USA Zhejiang Laboratory of s.s.ems.and Precis.on Medicine Zhejiang University Medical CenterHangzhou 311121China MOE Key Laboratory of Macromolecular s.nthes.s.and Functionalization Department of Polymer Science and EngineeringZhejiang UniversityHangzhou 310027China

Macroencaps.lation has.been widely us.d in cell therapy due to its.capability to provide immune-privileged s.tes.for implanted allogeneic or xenogeneic *** als. s.rves.to provide mechanical and phys.ochemical s.pport for maintaining cell expans.on and promoting therapeutic *** devices.s.ch as.membrane-controlled releas. s.s.ems.hydrogels.micronee-dle(MN)array patches.and three-dimens.onal(3D)s.ents.have s.own promis.ng in-lab and preclinical res.lts.in the maintenance of long-term cell s.rvival and the s.rengthening of treatment *** s.udies.focus.on expanding the applications.of thes. devices.to new cell-bas.d areas.s.ch as.chimeric antigen receptor(CAR)-T cell delivery,cardiovas.ular dis.as. therapy,and the exploration of new materials.cons.ruction methods.and working principles.to augment treatment efficacy and prolong therapy ***,we s.rvey innovative platforms.and approaches.as.well as.trans.ation outcomes.for advancing the performance and applications.of macrodevices.for cell-bas.d therapies.A dis.us.ion and critique regarding future opportunities.and challenges.is.als. provided.

关键词： Drug delivery Cell encaps.lation Cell therapy Cell trans.lantation Biomedical devices

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Facial fillers.Relevant anatomy,injection techniques.and complications

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World Journal of Otorhinolaryngology-Head and Neck s.rgery 2023年第3期9卷 227-235页

作者： nicholas W.Clark Debbie R.Pan Dane M.Barrett Duke Univers.ty Department of Head and Neck s.rgery and Communication s.iences DurhamNorth CarolinaUSA

Objective:The aim of this.review article is.to dis.us. the currently available facial fillers.their differences.and indications.relevant anatomy,injection techniques.and avoidance and management of *** s.urces.Clinical experience and s.ientific ***:Revers.l of facial aging via filler injection has.been around s.nce the late 1800s.with the initial us. of detrimental ***,many s.fe and effective products.exis. and can be tailored to the individual patient’’s.des.red *** the evolution of both products.and injection techniques.the rate of complications.with facial filler us. is.***,providers.offering facial filler injections.s.ould have detailed knowledge of facial anatomy,including facial planes.and s.ft tis.ue *** injection techniques.*** techniques.s.ould be us.d,depending on the anatomic *** s.ould als. know how to avoid and manage complications.

关键词： cos.etic facial filler injection plas.ic s.rgery

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Antitangling and manufacturable Fog Harps.for high‐efficiency water harves.ing

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Droplet 2023年第4期2卷 38-44页

作者： Jimmy K.Kaindu Kevin R.Murphy nicholas G.Kowals.i Alexandra N.Jones.Matthew Davis.Fleming Brook s.Kennedy Jonathan B.Boreyko Department of Mechanical Engineering Virginia TechBlacksburgVirginiaUSA Department of Biomedical Engineering and Mechanics Virginia TechBlacksburgVirginiaUSA s.hool of Architecture and Des.gn Virginia TechBlacksburgVirginiaUSA s.ms.reen Inc. ConklinNew YorkUSA

Fog Harps.harves. s.bs.antially more water than conventional mes.‐bas.d ***,to date,all large‐s.ale Fog Harps.have been impractically hand‐wound at low wire tens.ons.and s.ffer from elas.ocapillary wire ***,we develop large‐s.ale and high‐tens.on Fog Harps.that are manufacturable and *** Fog Harps.retain the record‐s.tting fog harves.ing efficiency(η≈17%)of their optimized s.ale‐model counterparts.while uniquely enabling practical real‐life *** was.achieved by adapting the indus.rial proces. for making harp s.reens.a pre‐exis.ing technology us.d for s.reening s.lid *** critical tens.on required to minimize wire tangling was.rationalized by an improved elas.ocapillary tangling model.

关键词： harves.ing capillary rational

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