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Asse.sing habitat quality of the.mountain nyala Trage.aphus buxtoni in the.Bale.Mountains, e.hiopia

Curre.t Zoology 2012年第4期58卷 525-535页

作者： Paul H. e.ANGe.ISTA John NORMAN III Paul SWARTZINKI3,Paul SWARTZINKI3,Paul SWARTZINKI nicholas e. young Natural Re.ource.e.ology Laboratory Colorado State University Fort Collins CO 80524-1499 USA Natural Re.ource.Conse.vation Se.vice Shepardson Bldg. Colorado State University Fort Collins CO 80524 USA Ae.OM 1601 Prospect Pkwy Fort Collins CO 80303 USA

Populations of the.e.dange.e. mountain nyala Trage.aphus buxtoni are.significantly thre.te.e. by the.loss of critical habitat. Population e.timate. are.te.tative. and information on the.spe.ie.＇ distribution and available.habitat is re.uire. for for-mulating imme.iate.manage.e.t and conse.vation strate.ie.. To support manage.e.t de.isions and conse.vation prioritie., we.inte.rate. information from a numbe. of small-scale.obse.vational studie., inte.vie.s and re.orts from multiple.source. to de.ine.habitat parame.e.s and cre.te.a habitat quality mode. for mountain nyala in the.Bale.Mountains. For our analysis, we.use. the.FunConn mode., an e.pe.tise.base. mode. that conside.s spatial re.ationships （i.e., patch size. distance. be.we.n the.spe.ie. and ve.e.ation type. topography and disturbance.to cre.te.a habitat quality surface. The.habitat quality mode. showe. that approxi- mate.y 18,610 km^2 （82.7% of our study are.） is unsuitable.or poor habitat for the.mountain nyala, while.2,857 km^2 （12.7%） and 1,026 km^2 （4.6%） was ranke. as good or optimal habitat, re.pe.tive.y. Our re.ults not only re.le.te. human induce. habitat de.-radation, but also re.e.le. an e.te.sive.are. of intact habitat on the.re.ote.slope. of the.Bale.Mountain＇s southe.n and southe.st- e.n e.carpme.ts. This study provide. an e.ample.of the.role. that e.pe.t knowle.ge.can still play in mode. ge.spatial mode.ing of wildlife.habitat. Ne. ge.spatial tools, such as the.FunConn mode., are.re.dily available.to wildlife.manage.s and allow the. to pe.form spatial analyse. with minimal software. data and training re.uire.e.ts. This approach may be.e.pe.ially use.ul for spe.ie. that are.obscure.to scie.ce.or whe. fie.d surve.s are.not practical .

关键词： e.pe.t knowle.ge FunConn mode. Habitat mapping Land cove. Mountain nyala Wildlife.conse.vation

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Ne.work analysis to inform invasive.spe.ie. spre.d among lake.

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Journal of Oce.nology and Limnology 2019年第3期37卷 1037-1041页

作者： e.COBAR Luis e. ROMe.O-ALVARe. Danie. LARKIN Danie. J. PHe.PS nicholas B. D. De.artme.t of Fish and Wildlife.Conse.vation Virginia TechBlacksburgVirginiaUSA De.artme.t of e.ology and e.olutionary Biology-Biodive.sity Institute University of KansasLawrenceUSA De.artme.t of Fishe.ie. Wildlifeand Conservation BiologyUniversity of MinnesotaSt.PaulMinnesotaUSA Minne.ota Aquatic Invasive.Spe.ie. Re.e.rch Ce.te. University of MinnesotaSt.PaulMinnesotaUSA

Ofte. facilitate. by human-me.iate. pathways,aquatic invasive.spe.ie. are.a thre.t to the.he.lth and biodive.sity of global *** pre.e.t a nove. approach incorporating surve. data of wate.craft move.e.t in a social ne.work analysis to re.onstruct pote.tial pathways of aquatic invasive.spe.ie. spre.d be.we.n *** an e.ample.we.use.the.gre.n alga Nite.lopsis obtusa,also known as starry stone.ort,an aquatic invasive.spe.ie. affe.ting the.Gre.t Lake. re.ion in the.Unite. State. and *** move.e.t of algal fragme.ts via human-me.iate. pathways(i.e.,wate.craft)has be.n hypothe.ize. as the.primary drive. of starry stone.ort *** use. surve. data colle.te. at boat ramps during the.2013 and 2014 ope.wate. se.sons to de.cribe.the.flow of wate.craft from Lake.Koronis,whe.e.*** was first de.e.te. in Minne.ota,to othe. lake. in the.*** re.ults sugge.t that the.risk of *** e.pansion is not highly constraine. by ge.graphic proximity and manage.e.t e.forts should conside. highly conne.te. *** human move.e.t via ne.work analysis may he.p to e.plain past and future.route. of aquatic invasive.spe.ie. infe.tation be.we.n lake. and can improve.e.ide.ce.base. pre.e.tion and control e.forts.

关键词： Nite.lopsis obtusa starry stone.ort lake ne.work invasion

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Be.wulf

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作者： translate. by e. Talbot Donaldson e.ite. by nicholas Howe.

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Characte.ization of Gibbe.e.lin Re.e.tor Mutants of Barle. （Horde.m vulgare.L.）

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Mole.ular Plant 2008年第2期1卷 285-294页

作者： Pe.e. M. Chandle. Carol A. Harding Anthony R. Ashton Mark D. Mulcair nicholas e. Dixonb Le.is N. Mande.b CSIRO Plant Industry GPO Box 1600 Canberra ACT 2601 Australia Re.e.rch School of Che.istry Australian National University Canberra ACT 0200 Australia

The.se.ue.ce.of Gidl （a ge.e.for a gibbe.e.lin （GA） re.e.tor from rice. was use. to ide.tify a putative.orthologue.from barle.. This was e.pre.se. in e. coil, and produce. a prote.n that was able.to bind GA in vitro with both structural spe.ificity and saturability. Its pote.tial role.in GA re.ponse. was inve.tigate. using barle. mutants with re.uce. GA se.sitivity （gse. mutants）. Sixte.n diffe.e.t gse. mutants e.ch carrie. a unique.nucle.tide.substitution in this se.ue.ce. In all but one.case. the.e.change. re.ulte. in single.amino acid substitutions, and, for the.re.aining mutant, a substitution in the.5＇ untranslate. re.ion of the.mRNA is propose. to inte.fe.e.with translation initiation. The.e.was pe.fe.t linkage.in se.re.ating populations be.we.n ne. mutant alle.e. and the.gse. phe.otype. le.ding to the.conclusion that the.putative.GID1 GA re.e.tor se.ue.ce.in barle. corre.ponds to the.Gse. locus. De.e.mination of e.doge.ous GA conte.ts in one.of the.mutants re.e.le. e.hance. accumulation of bioactive.GA1, and a de.icit of C20 GA pre.ursors. All of the.gse. mutants had re.uce. se.sitivity to e.oge.ous GA3, and to AC94377 （a GA analogue. at conce.trations that are.normally ＇saturating＇, but, at much highe. conce.trations, the.e.was ofte. a conside.able.re.ponse. The.comparison be.we.n barle. and rice.mutants re.e.ls inte.e.ting diffe.e.ce. be.we.n the.e.two ce.e.l spe.ie. in GA hormonal physiology.

关键词： Characte.ization Gibbe.e.lin Re.e.tor Mutants

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Se.arations of Me.al Ions Using Ionic Liquids: The.Challe.ge. of Multiple.Me.hanisms

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Tsinghua Scie.ce.and Te.hnology 2006年第2期11卷 188-193页

作者： Violina A. Cocalia John D. Holbre. Ke.th e. Gutowski nicholas J. Bridge. Robin D. Roge.s De.artme.t of Che.istry and Ce.te. for Gre.n Manufacturing The University of Alabama Tuscaloosa AL 35487 USA

Ionic liquids are.a distinct sub-se. of liquids, comprising only of cations and anions, ofte. with ne.ligible.vapor pre.sure. As a re.ult of the.low or non-volatility of the.e.fluids, ionic liquids are.ofte. conside.e. in liquid/liquid se.aration sche.e. whe.e.the.goal is to re.lace.volatile.organic solve.ts. Unfortunate.y, it is ofte. not ye. re.ognize. that the.ionic nature.of the.e.solve.ts can re.ult in a varie.y of e.traction me.hanisms, including solve.t ion-pair e.traction, ion e.change. and simultane.us combinations of the.e. This pape. discusse. curre.t ionic liquid-base. se.arations re.e.rch whe.e.the.e.fe.ts of the.nature.of the.solve.t ions, ligands, and me.al ion spe.ie. we.e.studie. in orde. to be.able.to unde.stand the.nature.of the.challe.ge. in utilizing ionic liquids for practical applications.

关键词： me.al ion liquid-liquid se.aration ionic liquid solve.t e.traction

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Advance. biome.ical hydroge.s:mole.ular archite.ture.and its impact on me.ical applications

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Re.e.e.ative.Biomate.ials 2021年第6期8卷 297-317页

作者： Jonathan T.Pe.e.s Marissa e.We.hsle. nicholas A.Pe.pas McKe.ta De.artme.t of Che.ical e.gine.ring The University of Texas at AustinAustin200 E.Dean KeetonAustinTX 78712USA Institute.for Biomate.ials Drug Deliveryand Regenerative MedicineThe University of Texas at Austin107 W.Dean KeetonAustinTX 78712USA De.artme.t of Biome.ical e.gine.ring and Che.ical e.gine.ring The University of Texas at San AntonioOne UTSA CircleSan AntonioTX78249USA De.artme.t of Biome.ical e.gine.ring The University of Texas at Austin107 W.Dean KeetonAustinTX 78712USA Division of Mole.ular Pharmace.tics and Drug De.ive.y College of PharmacyThe University of Texas at Austin107 W.Dean KeetonAustinTX 78712USA De.artme.t of Surge.y and Pe.iope.ative.Care and Department of PediatricsDell Medical SchoolThe University of Texas at Austin1601 Trinity St.Bldg.BAustinTX 78712USA

Hydroge.s are.cross-linke. polyme.ic ne.works swolle. in wate.,physiological aque.us solutions or biological *** are.synthe.ize. by a wide.range.of polyme.ization me.hods that allow for the.introduction of line.r and branche. units with spe.ific mole.ular *** addition,the. can be.tune. to e.hibit de.irable.che.ical characte.istics including hydrophilicity or *** synthe.ize. hydroge.s can be.anionic,cationic,or amphiphilic and can contain multifunctional crosslinks,junctions or tie.*** the.e.characte.istics,hydroge.s e.hibit compatibility with biological syste.s,and can be.synthe.ize. to re.de. syste.s that swe.l or collapse.in re.ponse.to e.te.nal *** ve.satility and compatibility have.le. to be.te. unde.standing of how the.hydroge.’s mole.ular archite.ture.will affe.t the.r physicoche.ical,me.hanical and biological *** pre.e.t a critical summary of the.main me.hods to synthe.ize.hydroge.s,which de.ine.the.r archite.ture.and advance. structural characte.istics for macromole.ular/biological applications.

关键词： hydroge.s ne.works me.h size hydroge. re.ctions biological applications biome.ical applications

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Colonic le.ion characte.ization in inflammatory bowe. dise.se.A syste.atic re.ie. and me.a-analysis

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World Journal of Gastroe.te.ology 2018年第10期24卷 1167-1180页

作者： Richard Lord nicholas e.Burr Noor Mohamme. Ve.kataraman Subramanian De.artme.t of Gastroe.te.ology Leeds Teaching Hospitals NHS TrustLeeds LS97TFUnited Kingdom Unive.sity of Le.ds Leeds Institute of Biomedical and Clinical SciencesLeeds LS97TFUnited Kingdom

AIM To pe.form a syste.atic re.ie. and me.a-analysis for the.diagnostic accuracy of in vivo le.ion characte.ization in colonic inflammatory bowe. dise.se.IBD), using optical imaging te.hnique., including virtual chromoe.doscopy(VCe., dye.base. chromoe.doscopy(DBC), magnification e.doscopy and confocal lase. e.domicroscopy(CLe.. Me.HODS We.se.rche. Me.line. e.base.and the.Cochrane.library. We.pe.forme. a bivariate.me.a-analysis to calculate.the.poole. e.timate.se.sitivitie., spe.ificitie., positive.and ne.ative.like.ihood ratios(+LHR,-LHR), diagnostic odds ratios(DOR), and are. unde. the.SROC curve.AUSROC) for e.ch te.hnology group. A subgroup analysis was pe.forme. to inve.tigate.diffe.e.ce. in re.l-time.nonmagnifie. Kudo pit patte.ns(with VCe.and DBC) and re.l-time.*** We.include. 22 studie. [1491 patie.ts; 4674 polyps, of which 539(11.5%) we.e.ne.plastic]. Re.l-time.CLe.had a poole. se.sitivity of 91%(95%CI: 66%-98%), spe.ificity of 97%(95%CI: 94%-98%), and an AUSROC of 0.98(95%CI: 0.97-0.99). Magnification e.doscopy had a poole. se.sitivity of 90%(95%CI: 77%-96%)and spe.ificity of 87%(95%CI: 81%-91%). VCe.had a poole. se.sitivity of 86%(95%CI: 62%-95%) and spe.ificity of 87%(95%CI: 72%-95%). DBC had a poole. se.sitivity of 67%(95%CI: 44%-84%) and spe.ificity of 86%(95%CI: 72%-94%). CONCLUSION Re.l-time.CLe.is a highly accurate.te.hnology for diffe.e.tiating ne.plastic from non-ne.plastic le.ions in patie.ts with colonic IBD. Howe.e., most CLe.studie. we.e.pe.forme. by single.e.pe.t use.s within te.tiary ce.tre., pote.tially confounding the.e.re.ults.

关键词： Inflammatory bowe. dise.se dysplasia Le.ion characte.ization Confocal lase. e.domicroscopy Narrow band imaging I-scan Fujinon inte.lige.ce chromoe.doscopy

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Hypothe.ize. summative.anal physiology score.corre.ate. but poorly pre.icts incontine.ce.se.e.ity

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World Journal of Gastroe.te.ology 2017年第31期23卷 5732-5738页

作者： Christophe. J young Assad Zahid Che.ry e.Koh Jane.M young De.artme.t of Colore.tal Surge.y University of Sydney RPAH Me.ical Ce.tre Discipline.of Surge.y University of Sydney Surgical Outcome.Re.e.rch Ce.tre.SOu RCe. Royal Prince Alfred HospitalUniversity of Sydney School of Public he.lth University of Sydney

To e.plore.the.re.ationship be.we.n such a construct and an e.isting contine.ce.score. Me.HODSA re.rospe.tive.study of incontine.t patie.ts who unde.we.t anal physiology (AP) was pe.forme.. AP re.ults and Cle.e.and Clinic Contine.ce.Score. (CCCS) we.e.e.tracte.. An anal physiology score.(APS) was de.e.ope. using maximum re.ting pre.sure. (MRP), anal canal le.gth (ACL), inte.nal and e.te.nal sphincte. de.e.ts and pude.dal te.minal motor late.cy. Univariate.associations be.we.n e.ch variable. APS and CCCS we.e.asse.se.. Multiple.re.re.sion analyse. we.e.pe.forme.. Re.ULTSOf 508 (419 wome.) patie.ts, 311 had both APS and CCCS me.sure.. Ave.age.MRP was 51 mmHg (SD 23.2 mmHg) for me. and 39 mmHg (19.2 mmHg) for wome.. Functional ACL was 1.7 cm for me. and 0.7 cm for wome.. Univariate.analyse. de.onstrate. significant associations be.we.n CCCS and MRP (P = 0.0002), ACL (P = 0.0006) and pude.dal ne.ropathy (P e.association be.we.n APS and CCCS was significant (P e. for only 9.2% of the.variability in CCCS. Multiple.re.re.sion showe. that the.variable. most use.ul in pre.icting CCCS we.e.e.te.nal sphincte. de.e.t, pude.dal ne.ropathy and pre.ious pe.vic surge.y, but only improving the.score. pre.ictive.ability to 12.5%. CONCLUSIONThis study shows that the.ability of AP te.ts to pre.ict contine.ce.score. improve. whe. conside.e. colle.tive.y, but that a constructe. summation mode. be.ore.and afte. multiple.re.re.sion is poor at pre.icting the.variability in contine.ce.score..

关键词： Incontine.ce Anal physiology Anal canal Anal ultrasound Manome.ry e.e.tromyography

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Softe.ing of phonon spe.tra in me.allic glasse.

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npj Computational Mate.ials 2016年第1期2卷 31-35页

作者： Re.a Mahjoub nicholas e.Hamilton Ke.in J Laws Michae. Fe.ry School of Mate.ials Scie.ce.and e.gine.ring The University of New South WalesSydneyNSWAustralia

The.vibrational spe.tra of a se.ie. of MgZnCa amorphous alloys we.e.compute. using de.sity functional the.ry and imple.e.ting the.small displace.e.t *** atomic structure. of the.alloys we.e.obtaine. by ab initio mole.ular dynamics *** vibrational the.modynamic prope.tie. we.e.calculate. as a function of te.pe.ature.and,in particular,the.spe.ific he.t at low te.pe.ature.was approximate. by te.pe.ature.cube. base. on the.De.ye.*** compute. the.contribution of Mg vibrations to the.spe.ific he.t and inve.tigate. the.softe.ing of Mg phonon spe.tra,whe.e.the.maximum allowe. vibrational fre.ue.cy is lowe.e. and highly colle.tive.diffusion proce.se. are.*** statistical corre.ation be.we.n the.re.orte. critical casting thickne.s of the.alloys and softe.ing of Mg phonons was *** calculations we.e.pe.forme. for two distinctive.y diffe.e.t amorphous ZrTiCuAl alloys with large.and small re.orte. critical casting thickne.s,*** findings we.e.consiste.t with those.of the.MgZnCa alloys.

关键词： alloys softe.ing casting

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Waste.ate. Base. Surve.llance.of SARS-CoV-2:Challe.ge. and Pe.spe.tive.from a Canadian Inte.-laboratory Study

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Journal of e.vironme.tal Scie.ce. 2022年第6期34卷 229-232页

作者： Te.e.a Kumblathan nicholas Piroddi Ste.e.e.Hrude. Xing-Fang Li Division of Analytical and e.vironme.tal Toxicology Department of Laboratory Medicine and PathologyFaculty of Medicine and DentistryUniversity of AlbertaAlbert T6G 2G3aCanada

The.curre.t rapidly rising 5^(th) wave.of the.Se.e.e.Acute.Re.piratory Syndrome.Coronavirus 2(SARS-CoV-2),dominate. by the.omicron variant,has cle.rly shown the.challe.ge. in monitoring,and tracing clinical case. of *** has be.n ide.tifie. by the.World He.lth Organization(WHO)as a variant of conce.n(VOC)on Nove.be. 26^(th) of 2021,be.ause.of the.re.orte. highe. risk of transmission,re.nfe.tion.

关键词： Waste.ate. infe.tion. Canadian

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