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Music as me.icine.fo. traumatic brain injury:a pe.spe.tive.o. future.re.e.rch dire.tio.s

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Ne.ral Re.e.e.atio. Re.e.rch 2024年第10期19卷 2105-2106页

作者： Antho.y e.Kline.e.e.i H.Mo.cho.as Co.ina o.Bo.di De.artme.t o. Physical Me.icine.Re.abilitatio. University of PittsburghPittsburghPAUSA Safar Ce.te. fo. Re.uscitatio. Re.e.rch University of PittsburghPittsburghPAUSA Ce.te. fo. Ne.ro.cie.ce University of PittsburghPittsburghPAUSA De.artme.t o. Critical Care.Me.icine University of PittsburghPittsburghPAUSA Ce.te. fo. the.Ne.ral Basis o. Co.nitio. University of PittsburghPittsburghPAUSA De.artme.t o. Psycho.o.y University of PittsburghPittsburghPAUSA De.artme.t o. Ne.ro.io.o.y University of PittsburghPittsburghPAUSA

Traumatic brain injury(TBI) impacts 69 millio. individuals glo.ally e.ch ye.r and is a le.ding cause.o. de.th and disability(De.an e. al.,2019).The.majo.ity o. mo.e.ate.to.se.e.e.TBI survivo.s e.dure.lo.g-lasting disturbance. in mo.o.,co.nitive.and affe.t that ne.ative.y impacts the.r *** a ple.ho.a o. re.e.rch o. pharmaco.o.ical inte.ve.tio.s fo. TBI has be.n co.ducte.,no.e.has translate. to.the.clinic,thus advo.ating fo. the.e.aluatio. o. no.pharmaco.o.ical the.ape.tic appro.che. that may incre.se.translatio.al succe.s.

关键词： injury traumatic

Co.le.tive.co.e.e.t e.issio. o. e.e.tro.s in stro.g lase. fie.ds and pe.spe.tive.fo. hard x-ray lase.s

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Matte. and Radiatio. at e.tre.e. 2024年第2期9卷 1-3页

作者： e.G.Ge.fe. A.M.Fe.o.o. o.Klimo.S.We.e. e.tre.e.Light Infrastructure.e.IC ELI Beamlines Facility25241 Dolní BřežanyCzech Republic HiLASe.Ce.tre Institute of Physics of the Czech Academy of Sciences25241 Dolní BřežanyCzech Republic Natio.al Re.e.rch Nucle.r Unive.sity Me.hI Moscow 115409Russia FNSPe Czech Technical University in Prague11519 PragueCzech Republic

Co.e.e.t mo.io. o. particle. in a plasma can imprint itse.f o. *** re.e.t adve.t o. high-po.e. lase.s—allo.ing the.no.line.r inve.se.Co.pto.-scatte.ing re.ime.to.be.re.che.—has o.e.e. the.po.sibility o. lo.king at co.le.tive.e.fe.ts in lase.–plasma *** ce.tain co.ditio.s,the.co.le.tive.inte.actio. o. many e.e.tro.s with a lase. pulse.can ge.e.ate.co.e.e.t radiatio. in the.hard x-ray *** pe.spe.tive.pape. e.plains the.limitatio.s unde. which such a re.ime.might be.attaine..

关键词： lase. scatte.ing co.e.e.t

Ste.o.dal scaffo.d de.o.atio.s in So.anum alkalo.d bio.ynthe.is

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Mo.e.ular Plant 2024年第8期17卷 1236-1254页

作者： Ro.alind Lucie. Mo.ame. o.Kamile.n Yo.o.Nakamura So.ia Se.e.iuk Ranjit Barbo.e.Je.s Wurlitze. Maritta Kune.t Sarah He.nicke.Sarah e.o.Co.no. Prashant D.So.awane De.artme.t o. Natural Pro.uct Bio.ynthe.is Max Planck Institute for Chemical Ecology07745 JenaGermany Re.e.rch Gro.p Bio.ynthe.is and NMR Max Planck Institute for Chemical Ecology07745 JenaGermany Bio.he.ical Scie.ce. Divisio. CSIR-National Chemical LaboratoryPune 411008MaharashtraIndia

Ste.o.dal glyco.lkalo.ds(SGAs)are.spe.ialize. me.abo.ite. pro.uce. by hundre.s o. So.anum spe.ie.,including impo.tant ve.e.able.cro.s such as to.ato.po.ato.and *** it has be.n kno.n that SGAs play impo.tant ro.e. in de.e.se.in plants and“anti-nutritio.al"e.fe.ts(e.g.,to.icity and bitte.ne.s)to.humans,many o. the.e.mo.e.ule. have.do.ume.te. anti-cance.,anti-micro.ial,antiinflammato.y,anti-viral,and anti-pyre.ic *** the.e.α-so.aso.ine.andα-so.amargine.iso.ate. fro. black nightshade.So.anum nigrum)are.re.o.te. to.have.po.e.t anti-tumo.,anti-pro.ife.ative.and anti-inflammato.y ***,α-so.aso.ine.andα-so.amargine.alo.g with the.co.e.ste.o.dal aglyco.e.so.aso.ine.are.the.mo.t wide.pre.d SGAs pro.uce. amo.g the.So.anum ***,it is still unkno.n ho. plants synthe.ize.the.e.bio.ctive.ste.o.dal *** co.parative.me.abo.o.ictranscripto.e.guide. appro.ch,bio.ynthe.ic lo.ic,co.binato.ial e.pre.sio. in Nico.iana be.thamiana,and functio.al re.o.binant e.zyme.assays,he.e.we re.o.t the.disco.e.y o. 12 e.zyme. fro. *** that co.ve.ts the.starting cho.e.te.o. pre.urso.to.so.aso.ine.aglyco.e.and the.do.nstre.mα-so.aso.ine.α-so.amargine.and malo.yl-so.amargine.SGA *** furthe. ide.tifie. six e.zyme. fro. cultivate. e.gplant that catalyze.the.pro.uctio. o.α-so.aso.ine.α-so.amargine.and malo.yl-so.amargine.SGAs fro. so.aso.ine.aglyco.e.via glyco.ylatio. and atypical malo.ylatio. *** wo.k pro.ide. the.ge.e.to.l bo. and platfo.m fo. e.gine.ring the.pro.uctio. o. high-value.ste.o.dal bio.ctive.mo.e.ule. inhe.e.o.o.o.sho.ts usingsynthe.icbio.o.y.

关键词： ste.o.dal glyco.lkalo.ds So.anum bio.ynthe.ic pathway α-so.amargine malo.yl-so.amargine spe.ialize. me.abo.ite.

Impact o. de.ice.re.istance. in the.pe.fo.mance.o. graphe.e.base. te.ahe.tz pho.o.e.e.to.s

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Fro.tie.s o. o.to.le.tro.ics 2024年第2期17卷 87-97页

作者： o.Caste.ló So.ía M.Lópe. Baptista K.Watanabe.T.Taniguchi e.Die. J.e.Ve.ázque.-Pére. Y.M.Me.iani J.M.Caridad J.A.De.gado.No.ario De.artme.t o. Applie. Physics University of Salamanca37008 SalamancaSpain Unidad de.e.ce.e.cia e. Luz y Mate.ia e.tructurada(LUMe.) University of Salamanca37008 SalamancaSpain Re.e.rch Ce.te. fo. e.e.tro.ic and o.tical Mate.ials National Institute for Materials Science1-1 NamikiTsukuba 305-0044Japan Re.e.rch Ce.te. fo. Mate.ials Nano.rchite.to.ics National Institute for Materials Science1-1 NamikiTsukuba 305-0044Japan Nano.e.hno.o.y Gro.p USAL-NanolabUniversity of Salamanca37008 SalamancaSpain

In re.e.t ye.rs,graphe.e.fie.d-e.fe.t-transisto.s(GFe.s)have.de.o.strate. an o.tstanding po.e.tial fo. te.ahe.tz(THz)pho.o.e.e.tio. due.to.the.r fast re.po.se.and *** fe.ture. are.e.se.tial to.e.able.e.e.ging THz applicatio.s,including 6G wire.e.s co.municatio.s,quantum info.matio.,bio.maging and ***,the.o.e.all pe.fo.mance.o. the.e.pho.o.e.e.to.s may be.utte.ly co.pro.ise. by the.impact o. inte.nal re.istance. pre.e.te. in the.de.ice.so.calle. acce.s o. parasitic *** this wo.k,we.pro.ide.a de.aile. study o. the.influe.ce.o. inte.nal de.ice.re.istance. in the.pho.o.e.po.se.o. high-mo.ility dual-gate.GFe. *** dual-gate.archite.ture. allo. us to.fine.tune.de.re.se.the.inte.nal re.istance.o. the.de.ice.by an o.de. o. magnitude.and co.se.ue.tly de.o.strate.an impro.e. re.po.sivity and no.se.e.uivale.t-po.e. value. o. the.pho.o.e.e.to.,*** re.ults can be.well unde.sto.d by a se.ie. re.istance.mo.e.,as sho.n by the.e.ce.le.t agre.me.t fo.nd be.wee. the.e.pe.ime.tal data and the.0}e.ical *** findings are.the.e.o.e.re.e.ant to.unde.stand and impro.e.the.o.e.all pe.fo.mance.o. e.isting high-mo.ility graphe.e.pho.o.e.e.to.s.

关键词： Graphe.e THz Pho.o.e.e.to. Fie.d-e.fe.t transisto. Plasmo.ic

Highly De.e.tive.Dark Tio.(2) Mo.ifie. with Pt: e.fe.ts o. Pre.urso. Nature.and Pre.aratio. Me.ho. o. Pho.o.atalytic Pro.e.tie.

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Transactio.s o. Tianjin Unive.sity 2024年第2期30卷 198-209页

作者： e.D.Fakhrutdino.a o.A.Re.to.a T.A.Bugro.a I.Yu.o.syuk L.S.Kibis o.A.Sto.kus D.B.Vasilche.ko.o.V.Vo.yankina V.A.Sve.lychnyi Natio.al Re.e.rch To.sk State.Unive.sity TomskRussia 634050 No.o.ibirsk State.Unive.sity NovosibirskRussia 630090 Bo.e.ko. Institute.o. Catalysis NovosibirskRussia 630090 Niko.ae. Institute.o. Ino.ganic Che.istry NovosibirskRussia 630090

The.study fo.use. o. the.mo.ificatio. with platinum o. dark de.e.tive.titania o.taine. via pulse. lase. ablatio.. Bo.h the.me.ho. o. Pt intro.uctio. and the.nature.o. the.Pt pre.urso. we.e.varie.. All sample. e.hibite. similar phase.co.po.itio.s, spe.ific surface.are.s, and Pt co.te.ts. High-re.o.utio. transmissio. e.e.tro. micro.co.y co.ple. with pulse. Co.adso.ptio. re.e.le. incre.se. dispe.sity whe. pho.o.e.uctio. and the.hydro.o.itrate.co.ple. (Me._(4) N) _(2) [Pt _(2) (o.) _(2) (No._(3) ) _(8) ] we.e.use.. The.sample.fe.ture. a high co.te.t o. single.ato. spe.ie. and subnano.size. Pt cluste.s. The.X-ray pho.o.le.tro. spe.tro.co.y re.ults sho.e. that the.pho.o.e.uctio. me.ho. facilitate. the.appe.rance.o. a large. numbe. o. Pt ^(2+) state., which appe.re. o.ing to.the.stro.g me.al-suppo.t inte.actio. (SMSI) e.f e.t o. the.transfe. o. e.e.tro. de.sity fro. the.e.e.tro.-saturate. de.e.ts o. the.Tio._(2) surface.to.Pt ^(4+) . In the.hydro.e. e.o.utio. re.ctio., sample. with a significant fractio. o. the.Pt ^(2+) io.ic co.po.e.t, capable.o. ge.e.ating sho.t-live. Pt^(0) single.ato. site. unde. irradiatio. due.to.the.SMSI e.f e.t, e.hibite. the.highe.t pho.o.atalytic activity. The.0.5Pt(C)/Tio.(2) -Ph sample.e.hibite. the.highe.t hydro.e. yie.d with a quantum e.ficie.cy o. 0.53, re.aining its activity e.e. afte. 8 h o. o.e.atio..

关键词： Dark(black)Tio.(2) Pulse. lase. ablatio. Platinum re.uctio. me.ho. Pre.urso. type Pho.o.atalysis Hydro.e. e.o.utio. re.ctio.

e.fe.tive.e.s o. ive.me.tin mass drug administratio. in the.co.tro. o. so.l-transmitte. he.minth infe.tio.s in e.de.ic po.ulatio.s: a syste.atic re.ie. and me.a-analysis

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Infe.tio.s Dise.se. o. Po.e.ty 2024年第1期13卷 1-15页

作者： Brando. Le.Nao.i e.Clarke.Nico.as Le.rand Susana Vaz Ne.y The.Kirby Institute University of New South WalesLevel 6Wallace Wurth BuildingSydneyNSW2052Australia

Backgro.nd Curre.t so.l-transmitte. he.minth(STH)co.tro. guide.ine. e.do.se.the.use.o. albe.dazo.e.o. me.e.-dazo.e.fo. scho.l-base. targe.e. pre.e.tive.che.o.he.apy(PC),ye. the.r re.uce. e.ficacy against Stro.gylo.de. ste.c-o.alis and Trichuris trichiura pre.e.ts significant *** e.ide.ce.indicate. that co.munity-wide.PC[o. mass drug administratio.(MDA)]using ive.me.tin,co.mo.ly use. in o.he. ne.le.te. tro.ical dise.se.NTD)co.tro. pro.rams,may play an impo.tant ro.e.in co.tro.ling the.e.*** co.ducte. a syste.atic re.ie. and me.a-analysis to.e.aluate.the.e.fe.tive.e.s o. ive.me.tin PC in re.ucing STH pre.ale.ce.in e.de.ic *** We.se.rche. Pubme.,e.BASe.and We. o. Scie.ce.o. Fe.ruary 14,2023,fo. studie. that inve.tigate. the.e.fe.tive.e.s o. ive.me.tin PC,e.the. alo.e.o. in co.binatio. with o.he. anthe.mintic drugs,o. STH infe.-tio.s,and pro.ide. a me.sure.o. STH pre.ale.ce.be.o.e.and afte. *** calculate. po.le. pre.ale.ce.re.uctio.s fo. e.ch STH using rando.-e.fe.ts *** pro.o.o. is available.o. PRo.Pe.o.re.istratio. numbe. CRD42023401219).Re.ults A to.al o. 21 we.e.e.igible.fo. the.syste.atic re.ie.,o. which 15 we.e.e.igible.fo. *** studie. de.ive.e. ive.me.tin thro.gh *** po.le. pre.ale.ce.re.uctio. o. *** fo.lo.ing MDA with ive.me.-tin alo.e.was 84.49%(95%CI:54.96-94.66)acro.s five.studie. and 81.37%(95% CI:61.62-90.96)acro.s se.e. studie. with o. witho.t *** pre.ale.ce.re.uctio. o. *** was 49.93%(95%CI:18.23-69.34)acro.s five.studie. with ive.me.tin alo.e.and 89.40%(95%CI:73.66-95.73)acro.s thre. studie. with the.additio. o. *** was high he.e.o.e.e.ty fo. all synthe.e.(I^(2)>65%).Co.clusio.s This study unde.sco.e. the.ke. ro.e.o. ive.me.tin-base. MDA in addre.sing limitatio.s in curre.t glo.al STH guide.ine. in te.ms o. limite. e.ficacy against *** and *** o. the.e.findings,re.ising inte.-natio.al STH guide.ine. to.include.i

关键词： So.l-transmitte. he.minths Ive.me.tin Albe.dazo.e Mass drug administratio. Pre.e.tive.che.o.he.apy

The.e.fe.t o. the.co.ce.tratio. o. plastic waste.o. the.fo.matio. o. re.ctio. pro.ucts o. the.Ti–Pe. syste.

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Gre.n Che.ical e.gine.ring 2024年第3期5卷 374-382页

作者： Ale.se. e.Matve.v To.sk Scie.tific Ce.te. o. the.Sibe.ian Branch o. the.Russian Acade.y o. Scie.ce.

The.pape. pre.e.ts re.e.rch re.ults o. the.synthe.is, phase.co.po.itio., and structure.o. pro.ucts o.taine. by highly e.o.he.mic re.ctio.s be.wee. Ti and C10H8o.mixture.co.po.e.ts, de.e.ding o. the.plastic waste.co.ce.tratio. and Ti po.de. dispe.sive.e.s, de.sity o. initial sample., and synthe.is me.ium. The.de.e.de.ce.o. the.phase.co.po.itio. and structure.o. the.synthe.is pro.ucts o. the.co.ce.tratio. o. the.po.yme.（plastic）co.po.e.t in the.initial Ti-Pe.(C10H8o.) syste. was fo.nd. Whe. the.plastic waste.co.te.t is 20 wt% to.25 wt%, synthe.is pro.ucts co.tain TiC0.5o..5–TiC0.6–0.75particle.agglo.e.ate.. Furthe. gro.th in the.po.ye.hyle.e.te.e.hthalate.co.te.t fro. 30 wt% to.45 wt% le.ds to.the.fo.matio. o. synthe.is pro.ucts co.sisting o. titanium carbide.TiC0.6–1.0). The.gase.0}s bypro.uct co.po.itio. o. the.e.o.he.mic re.ctio. is inve.tigate. fo. the.Ti–-C10H8o.mixture.co.po.itio.. It is fo.nd that the.gase.0}s by-pro.uct mo.tly co.tains hydro.e. and carbo. mo.o.ide.as we.l as impuritie. o. diffe.e.t hydro.arbo.s（me.hane. ace.yle.e. e.hane. e.he.e. and carbo. dio.ide. The.maximum adiabatic te.pe.ature.o. the.gas co.bustio. te.pe.ature.is 2080℃, which de.o.strate. the.po.sibility o. using gas as a fue. fo. e.e.gy ge.e.atio. de.ice.. Base. o. the.data o.taine., it is po.sible.to.cre.te.a basis fo. a ne. plastic waste.te.hno.o.y to.fabricate.carbide.co.taining mate.ials.

关键词： Plastic waste Titanium carbide Gre.n te.hno.o.y Hydro.e. synthe.is

Spatial analysis o. the.o.te.0}rthritis micro.nviro.me.t: te.hnique., insights, and applicatio.s

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Bo.e.Re.e.rch 2024年第1期12卷 1-19页

作者： Xiwe. Fan Anto.ia Rujia Sun Re.be. S.e.Yo.ng Isaac o.Afara Bre.t R.Hamilto. Lo.is Jun Ye.o.g Ro.s Crawfo.d Indira Prasadam Ce.tre.fo. Bio.e.ical Te.hno.o.ie. Queensland University of TechnologyBrisbaneQLDAustralia Scho.l o. Me.hanical Medical&Process EngineeringQueensland University of TechnologyBrisbaneQLDAustralia Ce.tral Analytical Re.e.rch Facility Queensland University of TechnologyBrisbaneQLDAustralia Mo.e.ular Ho.izo.s University of WollongongWollongongNSWAustralia De.artme.t o. Te.hnical Physics University of Eastern FinlandKuopioFinland Scho.l o. e.e.trical e.gine.ring and Co.pute. Scie.ce Faculty of EngineeringArchitecture and Information TechnologyUniversity of QueenslandBrisbaneQLDAustralia Ce.tre.fo. Micro.co.y and Micro.nalysis University of QueenslandBrisbaneQLDAustralia The.Prince.Charle. Ho.pital BrisbaneQLDAustralia

o.te.0}rthritis(o.)is a de.ilitating de.e.e.ative.dise.se.affe.ting multiple.jo.nt tissue.,including cartilage.bo.e.syno.ium,and adipo.e.*** pre.e.ts dive.se.clinical phe.o.ype. and distinct mo.e.ular e.do.ype.,including inflammato.y,me.abo.ic,me.hanical,ge.e.ic,and syno.ial ***,inno.ative.te.hno.o.ie. are.ne.de. to.suppo.t the.de.e.o.me.t o. e.fe.tive.diagno.tic and pre.isio. the.ape.tic *** analysis o. bulk o. tissue.e.tracts has limitatio.s due.to.te.hnical co.straints,causing challe.ge. in the.diffe.e.tiatio. be.wee. vario.s physio.o.ical and patho.o.ical phe.o.ype. in jo.nt *** issue.has le. to.standardizatio. difficultie. and hinde.e. the.succe.s o. clinical *** insights into.the.spatial variatio.s o. the.ce.lular and mo.e.ular structure. in o. tissue.,e.co.passing DNA,RNA,me.abo.ite.,and pro.e.ns,as we.l as the.r che.ical pro.e.tie.,e.e.e.tal co.po.itio.,and me.hanical attribute.,can co.tribute.to.a mo.e.co.pre.e.sive.unde.standing o. the.dise.se.*** re.o.ve. bio.o.y e.able. bio.o.ists to.inve.tigate.ce.ls within the.co.te.t o. the.r tissue.micro.nviro.me.t,pro.iding a mo.e.ho.istic vie. o. ce.lular *** advance. in inno.ative.spatial bio.o.y te.hnique. no. allo. intact tissue.se.tio.s to.be.e.amine. using vario.s-o.ics le.se.,such as ge.o.ics,transcripto.ics,pro.e.0}ics,and me.abo.o.ics,with spatial *** fusio. o. appro.che. pro.ide. re.e.rche.s with critical insights into.the.mo.e.ular co.po.itio. and functio.s o. the.ce.ls and tissue. at pre.ise.spatial ***,advance. imaging te.hnique.,including high-re.o.utio. micro.co.y,hype.spe.tral imaging,and mass spe.tro.e.ry imaging,e.able.the.visualizatio. and analysis o. the.spatial distributio. o. bio.o.e.ule.,ce.ls,and *** the.e.mo.e.ular imaging o.tputs to.co.ve.tio.al tissue.histo.o.y can facilitate.a mo.e.co.pre.e.sive.characte.izatio. o. dise.se.*** re.ie. summarize. the.re.

关键词： insight Spatial e.able

e.gine.ring nano.e.icine. fo. immuno.e.ic e.adicatio. o. cance. ce.ls:Re.e.t tre.ds and syne.gistic appro.che.

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Acta Pharmace.tica Sinica B 2024年第6期14卷 2475-2504页

作者： Ahme. o.e.zo.hby o.ar Samir Hagar e.e.am Ahme. So.iman Riham M.Abde.galil Yo.na M.e.mo.she.y Kadria A.e.kho.airy Mahmo.d L.Nasr Divisio. o. e.gine.ring in Me.icine.and Divisio. o. Re.al Me.icine Department of MedicineBrigham and Women's HospitalHarvard Medical SchoolBoston 02115MAUSA Cance. Nano.e.hno.o.y Re.e.rch Labo.ato.y(CNRL) Faculty of PharmacyAlexandria UniversityAlexandria 21521Egypt

Re.istance.to.cance. immuno.he.apy is mainly attribute. to.po.r tumo. immuno.e.icity as we.l as the.immuno.uppre.sive.tumo. micro.nviro.me.t(TMe.le.ding to.failure.o. immune.*** the.ape.tic strate.ie. including che.o.he.apy,radio.he.apy,pho.o.ynamic,pho.o.he.mal,magne.ic,che.o.ynamic,so.o.ynamic and o.co.ytic the.apy,have.be.n de.e.o.e. to.induce.immuno.e.ic ce.l de.th(ICD)o. cance. ce.ls and the.e.y e.icit immuno.e.icity and bo.st the.antitumo. immune.***,many challe.ge. hampe. the.clinical applicatio. o. ICD induce.s re.ulting in mo.e.t immuno.e.ic ***,we.o.tline.the.curre.t state.o. using nano.e.icine. fo. bo.sting ICD o. cance. ***,syne.gistic appro.che. use. in co.binatio. with ICD inducing nano.e.icine. fo. re.o.e.ing the.TMe.via targe.ing immune.che.kpo.nts,phago.yto.is,macro.hage.po.arizatio.,tumo. hypo.ia,auto.hagy and stro.al mo.ulatio. to.e.hance.immuno.e.icity o. dying cance. ce.ls we.e.*** furthe. highlight the.e.e.ging tre.ds o. using nano.ate.ials fo. trigge.ing amplifie. ICD-me.iate. antitumo. immune.*** re.iculum lo.alize. ICD,fo.use. ultraso.nd hype.the.mia,ce.l me.brane.camo.flage. nano.e.icine.,amplifie. re.ctive.o.yge. spe.ie.(Ro.)ge.e.atio.,me.allo.immuno.he.apy,io. mo.ulato.s and e.gine.re. bacte.ia are.amo.g the.mo.t inno.ative.*** challe.ge.,me.its and de.e.its o. ICD induce. nano.e.icine. we.e.also.discusse. with she.ding light o. the.future.ro.e.o. this te.hno.o.y in impro.ing the.o.tco.e. o. cance. immuno.he.apy.

关键词： Immuno.e.ic ce.l de.th Immuno.e.ic e.adicatio. Nano.e.icine. Drug de.ive.y Cance. immuno.he.apy Antitumo. immunity T ce.ls Tumo. asso.iate. antige.s Syne.gistic immune.re.po.se