Soft tissue sarcoma accounts for approximately 1% of all cancers diagnosed annually in the United States. When these rare malignant mesodermal tumours arise in the pelvis and extremities, they may potentially encase o...
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Soft tissue sarcoma accounts for approximately 1% of all cancers diagnosed annually in the United States. When these rare malignant mesodermal tumours arise in the pelvis and extremities, they may potentially encase or invade large calibre vascular structures. This presents a major challenge in terms of safe excision while also leaving acceptable surgical margins. In recent times, the trend has been towards limb salvage with vascular reconstruction in preference to amputation. Newer orthopaedic and vascular reconstructive techniques including both synthetic and autogenous graft reconstruction have made complex limb-salvage surgery feasible. Despite this, limb-salvage surgery with concomitant vascular reconstruction remains associated with higher rates of post-operative complications including infection and amputation. In this review we describe the initial presentation and investigation of patients presenting with soft tissue sarcomas in the pelvis and extremities, which involve vascular structures. We further discuss the key surgical reconstructive principles and techniques available for the management of these complex tumours, drawn from our institution's experience as a national tertiary referral sarcoma service.
Tungsten ditelluride(WTe_(2))is a layered transition metal dichalcogenide(TMD)that has attracted increasing research inter-est in recent ***_(2) has demonstrated large non-saturating magnetoresistance,potential for sp...
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Tungsten ditelluride(WTe_(2))is a layered transition metal dichalcogenide(TMD)that has attracted increasing research inter-est in recent ***_(2) has demonstrated large non-saturating magnetoresistance,potential for spintronic applications and promise as a type-II Weyl *** majority of works on WTe_(2) have relied on mechanically exfoliated flakes from chemical vapour transport(CVT)-grown crystals for their *** producing high-quality samples,this method is hindered by several disadvantages including long synthesis time,high-temperature annealing and an inherent lack of *** this work,a synthesis method is demonstrated that allows the production of large-area polycrystalline films of WTe_(2).This is achieved by the reaction of pre-deposited films of W and Te at a relatively low temperature of 550℃.Sputter X-ray photoelectron spectroscopy reveals the rapid but self-limiting nature of the oxidation of these WTe_(2) films in ambient *** WTe_(2) films are composed of areas of micrometre-sized nanobelts that can be isolated and offer potential as an alternative to CVT-grown *** nanobelts are highly crystalline with low defect densities indicated by transmission electron microscopy and show promising initial electrical results.
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