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腺病毒相关肝损伤患儿的临床特征及其影响因素

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肝脏 2024年第5期29卷 576-580页

作者：秦攸余邓巧妮宁南县人民医院儿科四川615400 宝鸡高新医院儿科陕西721700

目的了解腺病毒相关肝损伤患儿的临床特征及其影响因素。方法2019年4月至2023年4月宁南县人民医院收治的腺病毒感染患儿572例,其中肝损伤组236例,非肝损伤组336例。比较两组患儿的临床资料,多因素logistic回归分析腺病毒相关肝损伤患儿... 详细信息

目的了解腺病毒相关肝损伤患儿的临床特征及其影响因素。方法2019年4月至2023年4月宁南县人民医院收治的腺病毒感染患儿572例,其中肝损伤组236例,非肝损伤组336例。比较两组患儿的临床资料,多因素logistic回归分析腺病毒相关肝损伤患儿的危险因素。结果肝损伤组患儿男性、重症肺炎、胃肠炎、喘息、气促、呼吸困难、心力衰竭、混合感染比例分别为64.0%、19.1%、8.1%、37.3%、27.5%、20.3%、10.6%、53.0%,高于非肝损伤组的55.1%、12.5%、3.9%、25.6%、18.8%、12.8%、6.0%、42.3%;肝损伤组年龄、C反应蛋白(CRP)、降钙素原(PCT)、IL-6、ALT、AST、TBil、γ-谷氨酰转肽酶(GGT)、乳酸脱氢酶(LDH)和住院时间分别为(2.8±1.0)岁、(28.6±4.4)mg/L、(1.7±0.4)ng/mL、(78.4±20.8)pg/mL、(75.7±25.2)U/L、(162.3±45.6)U/L、(5.6±2.1)μmol/L、(18.1±10.3)U/L、(645.2±501.2)U/L和(10.5±2.3)d,高于非肝损伤组的(3.1±1.1)岁、(25.3±3.8)mg/L、(1.2±0.2)ng/mL、(36.5±16.3)pg/mL、(46.8±12.5)U/L、(124.6±40.3)U/L、(4.9±2.3)μmol/L、(12.4±8.6)U/L、(354.6±98.7)U/L和(8.1±1.6)d;肝损伤组支气管炎比例、Hb、IL-10分别为29.7%、(114.8±12.1)g/L、(1.08±0.4)pg/mL,低于非肝损伤组的30.1%、(119.4±10.5)g/L、(2.3±0.5)pg/mL,差异均有统计学意义(P<0.05)。重症肺炎[OR(95%CI):2.563(1.112~5.906)]、GGT[OR(95%CI):1.982(1.054~3.725)]、LDH[OR(95%CI):2.100(1.056~4.179)]是患儿发生肝损伤的独立危险因素。结论腺病毒相关肝损伤以年龄低的男性患儿常见,重症肺炎患儿肝损伤发生率高,临床症状以发热为主,重症肺炎、GGT、LDH是腺病毒相关肝损伤的影响因素。

关键词：腺病毒肝损伤临床特征影响因素儿童

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Dynamic analysis and regulation of the flexible pipe conveying fluid with a hard-magnetic soft segment

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Applied Mathematics and Mechanics(English Edition) 2022年第9期43卷 1415-1430页

作者： Zilong GUO qiao ni Wei CHEN Huliang DAI Lin WANG Department of Mechanics Huazhong University of Science and TechnologyWuhan 430074China Hubei Key Laboratory for Engineering Structural Analysis and Safety Assessment Wuhan 430074China State Key Lab of Digital Manufacturing Equipment and Technology School of Mechanical Science and EngineeringHuazhong University of Science and TechnologyWuhan 430074China State Key Laboratory of Structural Analysis for Industrial Equipment Dalian University of TechnologyDalian 116024Liaoning ProvinceChina

The recently developed hard-magnetic soft(HMS)materials can play a significant role in the actuation and control of medical devices,soft robots,flexible electronics,*** regulate the mechanical behaviors of the cantilevered pipe conveying fluid,the present work introduces a segment made of the HMS material located somewhere along the pipe *** on the absolute node coordinate formulation(ANCF),the governing equations of the pipe conveying fluid with an HMS segment are derived by the generalized Lagrange *** solving the derived equations with numerical methods,the static deformation,linear vibration characteristic,and nonlinear dynamic response of the pipe are *** result of the static deformation of the pipe shows that when the HMS segment is located in the middle of the pipe,the downstream portion of the pipe centerline will keep a straight shape,providing that the pipe is stable with a relatively low flow ***,it is possible to precisely regulate the ejection direction of the fluid flow by changing the magnetic and fluid *** is also found that the intensity and direction of the external magnetic field greatly affect the stability and dynamic response of the pipe with an HMS *** most cases,the magnetic actuation increases the critical flow velocity for the flutter instability of the pipe system and suppresses the vibration amplitude of the pipe.

关键词： hard-magnetic soft(HMS)material pipe conveying fluid absolute node coordinate formulation(ANCF) stability dynamic response regulation

Knowledge,attitude,practice and factors that influence the awareness of college students with regards to breast cancer

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World Journal of Clinical Cases 2022年第2期10卷 538-546页

作者： qiao-ni Zhang Hui-Xia Lu Clinical Medical College Dali UniversityDali 671003Yunnan ProvinceChina Gynecology and Obstetrics Clinical Medical CollegeDali UniversityDali 671003Yunnan ProvinceChina

BACKGROUND Breast cancer has the highest incidence of all global *** data show that breast cancer is becoming more prevalent in the younger ***,preventing breast cancer in young populations is a significant priority for public *** investigations of the incidence of breast cancer in young females have already been undertaken in China;however,none of these previous studies investigated the awareness of female college students with regards to breast *** To investigate the knowledge,attitude,and practice(KAP)of female college students in Yunnan with regards to breast cancer and a series of influential *** A random sample of 1387 female college students from two universities in Dali city were investigated by *** The total KAP scores for breast cancer were 9.86±2.50,3.19±2.01 and 13.31±2.49,*** linear regression analysis showed that educational grade was the most significant influential factor underlying the level of knowledge female college students had with regards to the treatment of breast cancer(Pnificant factors that influenced attitude(Pnificant factors that influenced behavior(P<0.05).The KAP of female college students in western Yunnan with regards to breast cancer were *** There is an urgent need to provide standardized publicity and educational strategies in China to improve the knowledge,attitude,and practice,of college students with regards to breast cancer.

关键词： Breast cancer Regression analysis Rejuvenation Western Yunnan College students Knowledge,attitude and practice

STABILITY AND LOCAL BIFURCATION IN A SIMPLY-SUPPORTED BEAM CARRYING A MOVING MASS

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Acta Mechanica Solida Sinica 2007年第2期20卷 123-129页

作者： Liu Pan ni qiao Wang Lin Yuan Liang Department of Mechanics Huazhong University of Science and Technology Wuhan 430074 China

The stability and local bifurcation of a simply-supported flexible beam （Bernoulli- Euler type） carrying a moving mass and subjected to harmonic axial excitation are investigated. In the theoretical analysis, the partial differential equation of motion with the fifth-order nonlinear term is solved using the method of multiple scales （a perturbation technique）. The stability and local bifurcation of the beam are analyzed for 1/2 sub harmonic resonance. The results show that some of the parameters, especially the velocity of moving mass and external excitation, affect the local bifurcation significantly. Therefore, these parameters play important roles in the system stability.

关键词： stability local bifurcation simply-supported beam moving mass

Nonlinear Vibration of A Loosely Supported Curved Pipe Conveying Pulsating Fluid under Principal Parametric Resonance

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Acta Mechanica Solida Sinica 2016年第5期29卷 468-478页

作者： Yangyang Luo Min Tang qiao ni Yikun Wang Lin Wang Department of Mechanics Huazhong University of Science and Technology Wuhan 430074 China Hubei Key Laboratory for Engineering Structural Analysis and Safety Assessment Wuhan 430074 China Wuhan Second Ship Design and Research Institute Wuhan 430205 China

In this paper,the nonlinear dynamics of a curved pipe is investigated in the case of principal parametric resonance due to pulsating flow and impact with loose *** coupled in-plane and out-of-plane governing equations with the consideration of von Karman geometric nonUnearity are presented and discretized via the differential quadrature method（DQM）.The nonlinear dynamic responses are calculated numerically to demonstrate the influence of pulsating ***,the impact is taken into *** influence of clearance on frettingwear damage,such as normal work rate,contact ratio and impact force level,is demonstrated.

关键词： curved governing quadrature clearance Karman numerically loose conveying parametric dynamical

NONLINEAR DYNAMICS AND SYNCHROniZATION OF TWO COUPLED PIPES CONVEYING PULSATING FLUID

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Acta Mechanica Solida Sinica 2014年第2期27卷 162-171页

作者： qiao ni Zilong Zhang Lin Wang Qin Qian Min Tang Hubei Key Laboratory for Engineering Structural Analysis and Safety Assessment Department of Mechanics Huazhong University of Science and Technology

In this paper, the nonlinear dynamical behavior of two coupled pipes conveying pulsating fluid is studied. The connection between the two pipes is considered as a distributed linear spring. Based on this consideration, the equations of motion of the coupled two-pipe system are obtained. The two coupled nonlinear partial differential equations, discretized using the fourth- order Galerkin method, are solved by a fourth-order Runge-Kutta integration algorithm. Results show that the connection stiffness has a significant effect on the dynamical behavior of the coupled system. It is found that for some parameter values the motion types of the two pipes might be synchronous.

关键词： pipe conveying pulsating fluid nonlinear dynamics coupled two-pipe system synchronization

New insight into the stability and dynamics of fluid-conveying supported pipes with small geometric imperfections

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Applied Mathematics and Mechanics(English Edition) 2021年第5期42卷 703-720页

作者： Kun ZHOU qiao ni Wei CHEN Huliang DAI Zerui PENG Lin WANG Department of Mechanics School of Aerospace EngineeringHuazhong University of Science and TechnologyWuhan 430074China Hubei Key Laboratory for Engineering Structural Analysis and Safety Assessment Wuhan 430074China Department of Mechanical Engineering Technische Universitat DarmstadtDarmstadt 64293Germany

In several previous studies,it was reported that a supported pipe with small geometric imperfections would lose stability when the internal flow velocity became sufficiently ***,however,it has become clear that this conclusion may be at best incomplete.A reevaluation of the problem is undertaken here by essentially considering the flow-induced static deformation of a *** the aid of the absolute nodal coordinate formulation(ANCF)and the extended Lagrange equations for dynamical systems containing non-material volumes,the nonlinear governing equations of a pipe with three different geometric imperfections are introduced and *** on extensive numerical calculations,the static equilibrium configuration,the stability,and the nonlinear dynamics of the considered pipe system are determined and *** results show that for a supported pipe with the geometric imperfection of a half sinusoidal wave,the dynamical system could not lose stability even if the flow velocity reaches an extremely high value of ***,for a supported pipe with the geometric imperfection of one or one and a half sinusoidal waves,the first-mode buckling instability would take place at high flow ***,based on a further parametric analysis,the effects of the amplitude of the geometric imperfection and the aspect ratio of the pipe on the static deformation,the critical flow velocity for buckling instability,and the nonlinear responses of the supported pipes with geometric imperfections are analyzed.

关键词： supported pipes conveying fluid geometric imperfection absolute nodal coordinate formulation(ANCF) static equilibrium configuration critical flow velocity nonlinear dynamics

TRANSFER MATRIX METHOD FOR ANALYZING VIBRATION AND DAMPING CHARACTERISTICS OF ROTATIONAL SHELL WITH PASSIVE CONSTRAINED LAYER DAMPING TREATMENT

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Acta Mechanica Solida Sinica 2010年第4期23卷 297-311页

作者： Jing Lu Yu Xiang Yuying Huang Xiaoni Li qiao ni College of Civil Engineering and Mechanics Huazhong University of Science and Technology Wuhan 430074 China Department of Automotive Engineering Guangxi University of Technology Liuzhou 545006 China

The first order differential matrix equations of the host shell and constrained layer for a sandwich rotational shell are derived based on the thin shell *** the layer wise principle and first order shear deformation theory, only considering the shearing deformation of the viscoelastic layer, the integrated first order differential matrix equation of a passive constrained layer damping rotational shell is established by combining with the normal equilibrium equation of the viscoelastic layer.A highly precise transfer matrix method is developed by extended homogeneous capacity precision integration *** numerical results show that present method is accurate and effective.

关键词： passive constrained layer damping rotational shell transfer matrix method first order differential matrix equation precise integration technology

Mesoporous TiO2 microparticles formed by the oriented attachment of nanocrystals： A super-durable anode material for sodium-ion batteries

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Nano Research 2018年第3期11卷 1563-1574页

作者： Liming Ling Ying Bai Huali Wang qiao ni Jiatao Zhang Feng Wu Chuan Wu Beijing Key Laboratory of Environmental Science and Engineering School of Materials Science and Engineering Beijing Institute of Technology Beijing 100081 China Collaborative Innovation Center of Electric Vehicles in Beijing Beijing 100081 China Beijing Key Laboratory of Construction-Tailorable Advanced Functional Materials and Green Applications School of Materials Science and Engineering Beijing Institute of Technology Beijing 100081 China

Spindle-shaped anatase TiO2 secondary particles were successfully fabricated via the oriented attachment of primary nanocrystals. By adjusting the concentration of tetrabutyl titanate, the size of the TiO2 nanocrystals and particles could be controlled, resulting in pore evolution. Pores for the random aggregation of secondary particles gradually transformed to nanopores originating from the oriented attachment of the primary nanocrystals, resulting in an excellent micro/nanostructure that increased the performance of a sodium-ion battery. The mesoporous TiO2 microparticle anode, with its unique combination of nanocrystals and uniform nanopores, displays super durability （95 mAh/g after 11,000 cycles at I C）, high initial efficiency （61.4%）, and excellent rate performance （265 and 77 mAh/g at 0.1 and 20 C, respectively）. In particular, at slow discharge （0.1 C） and fast charge （5, 50, and 100 C） rates, the anatase TiO2 shows remarkable initial charge capacities of 200, 119, and 56 mAh/g, corresponding to 172, 127, and 56 mAh/g, after 150 cycles, respectively, thus meeting the requirements for fast energy storage. This excellent performance can be attributed to the stability of the material and its high ionic conductivity, resulting from the stable architecture with a mesoporous microstructure and without the random aggregation of secondary particles. A fundamental understanding of the pore structure and controllable pore construction has been proven to be effective in increasing the rate capability and durability of nanostructured electrode materials.

关键词： oriented attachment pore evolution mesoporous TiO2 durabilit sodium ion batteries