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Privacy Preserving Blockchain Technique to Achieve Secure and Reliable Sharing of IoT Data

Computers, Materials & Continua 2020年第10期65卷 87-107页

作者： Bao Le nguyen E.Laxmi Lydia Mohamed Elhoseny Irina V.Pustokhina Denis A.Pustokhin Mahmoud Mohamed Selim Gia nhu nguyen K.Shankar Faculty of Information Technology Duy Tan UniversityDa Nang550000Vietnam Computer Science and Engineering Vignan’s Institute of Information TechnologyVisakhapatnam530049India Faculty of Computers and Information Mansoura UniversityMansoura35516Egypt Department of Entrepreneurship and Logistics Plekhanov Russian University of EconomicsMoscow115093Russia Department of Logistics State University of ManagementMoscow109542Russia Department of Mathematics College of Science&Humanities in AlaflajPrince Sattam bin Abdulaziz UniversityAlaflaj16278Saudi Arabia Graduate School Duy Tan UniversityDa Nang550000Vietnam Department of Computer Applications Alagappa UniversityKaraikudi630003India

In present digital era,an exponential increase in Internet of Things(IoT)devices poses several design issues for business concerning security and *** studies indicate that the blockchain technology is found to be a significant solution to resolve the challenges of data security exist in *** this view,this paper presents a new privacy-preserving Secure Ant Colony optimization with Multi Kernel Support Vector Machine(ACOMKSVM)with Elliptical Curve cryptosystem(ECC)for secure and reliable IoT data *** program uses blockchain to ensure protection and integrity of some data while it has the technology to create secure ACOMKSVM training algorithms in partial views of IoT data,collected from various data ***,ECC is used to create effective and accurate privacy that protects ACOMKSVM secure learning *** this study,the authors deployed blockchain technique to create a secure and reliable data exchange platform across multiple data providers,where IoT data is encrypted and recorded in a distributed *** security analysis showed that the specific data ensures confidentiality of critical data from each data provider and protects the parameters of the ACOMKSVM model for data *** examine the performance of the proposed method,it is tested against two benchmark dataset such as Breast Cancer Wisconsin Data Set(BCWD)and Heart Disease Data Set(HDD)from UCI AI *** simulation outcome indicated that the ACOMKSVM model has outperformed all the compared methods under several aspects.

关键词： Blockchain optimization elliptical curve cryptosystem security ant colony optimization multi kernel support vector machine

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Antibiotic usage in surgical sperm retrievals among IVF centers

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Asian Journal of Andrology 2022年第6期24卷 633-638页

作者： Le Dang Khoa Ngo Dinh Trieu Vy nguyen Minh Tai Loc Le Duc Thang Dang Tuan Anh nguyen Phuc Hieu Giang Huynh nhu nguyen Dinh Tao Le Hoang David J Handelsman IVFTA Tam Anh General HospitalHo Chi Minh 700000Vietnam IVFTA Tam Anh General HospitalHa Noi 100000Vietnam IVF Center 16A Ha Dong HospitalHa Noi 100000Vietnam ANZAC Research Institute University of Sydney and Concord Repatriation General HospitalHospital RoadConcordNSW 2139Australia

Surgical sperm retrieval(SSR)is currently one of the most common procedures in in vitro fertilization(IVF).However,a gap between the guidelines and routine clinical practice regarding antibiotic use in sSR,which might lead to antibiotic resistance,is a challenging problem worldwide.A cross-sectional survey was conducted from May 1,2021,to July 15,2021,to investigate antibiotic usage by medical professionals when performing SSR in IVF centers in *** confidential questionnaire comprised 12 items,including characteristics of the study population,awareness of antimicrobial resistance,attitude toward prescribing antibiotics,and current practice of prescribing antibiotics when performing *** were completed by 30 of 45 registered IVF centers(66.7%).Among 67 physicians working at those centers,the age and work-experience years(mean±standard deviation[s.d.])were 38.6±6.6 years and 11.2±7.0 years,*** 60%of them held a degree in Obstetrics and Gynecology,and over four-fifths were *** respondents"often/very often/always"raised awareness of antimicrobial resistance to their patients(83.3%),but only half of them"often/occasionally"prescribed antibiotics to patients with SSR in cases where the prescription would be *** one-tenth of respondents followed the recommendation from the American Urological Association using"prophylaxis only"for SSR *** more invasive SSR,physicians tended to prescribe more complicated and sometimes inappropriate *** conclusion,antibiotic usage in SSR was not always appropriate among IVF *** studies may define specific recommendations for regimens,intervention strategies,and programs to promote appropriate antibiotic use for SSR patients among IVF specialists.

关键词： antibiotic usage in vitro fertilization prophylaxis surgical sperm retrieval treatment

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Effect of heating time on structural,morphology,optical,and photocatalytic properties of g-C3N4 nanosheets

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Chinese Physics B 2020年第5期29卷 504-508页

作者： nguyen Manh Hung Le Thi Mai Oanh lam Thi Hang Pham Do Chung Pham Thi Duyen Dao Viet Thang nguyen Van Minh Center for Nano Science and Technology Hanoi National University of Education136 Xuan Thuy RoadCau Giay DistrictHanoi100000Vietnam Department of Physics Hanoi National University of Education136 Xuan Thuy RoadCau Giay DistrictHanoi100000Vietnam Faculty of Basic Sciences Hanoi University of Natural Resources and Environment41A Phu Dien RoadNorth Tu LiemHanoi100000Vietnam Hanoi University of Mining and Geology Duc Thang wardNorth Tu Liem DistrictHanoi100000Vietnam Military science Academy 322 Le Trong Tan streetDinh CongHoang MaiHanoi100000Vietnam

Effect of heating time on the structural,morphology,optical,and photocatalytic properties of graphitic carbon nitride(g-C3N4)nanosheets prepared at 550℃in Ar atmosphere is *** investigations are carried out by using x-ray diffraction(XRD),scanning electron microscopy(SEM),Fourier-transform infrared spectroscopy(FTIR),UV-vis absorption,and photoluminescence(PL).At a heating temperature of 550℃,g-C3N4 nanocrystals are formed after 0.5 h and become more orderly as the heating time *** surface area of the g-C3N4 nanosheets significantly increases as the preparation time *** g-C3N4 prepared in 2.5 h shows the highest photocatalytic performance,decomposing completely 10 ppm RhB solution under xenon lamp irradiation for 2.0 h.

关键词： nanosheets photocatalytic heating time Ar atmosphere

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A study implementing real-time PCR to identify Strongyloides species of third-stage larvae in human stool samples from Southern Vietnam

Infectious Medicine

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Infectious Medicine 2023年第3期2卷 229-236页

作者： Le Duc Vinh nguyen Kim Thach Huynh Hong Quang Do nhu Binh Tran Thi Duc Hanh nguyen Minh Toàn nguyen Trung Tuyen nguyen Thu Huong Department of Medical Parasitology Pham Ngoc Thach University of MedicineHo Chi Minh City 700000Vietnam Department of Fundamental Chemistry-Biochemistry Pham Ngoc Thach University of MedicineHo Chi Minh City 700000Vietnam Clinical Epidemiology Research Unit Institute of MalariologyParasitologyand Entomology Quy NhonBinh Dinh 55000Vietnam Department of Infectious Disease Military Hospital 103Hanoi 100000Vietnam Department of Epidemiology Hanoi University of Public HealthHanoi 100000Vietnam Department of Microbiology-Parasitology Hanoi University of Public HealthHanoi 100000Vietnam Department of Medicine University of Medicine and PharmacyVietnam National UniversityHanoi100000 Vietnam

Background:Strongyloidiasis,a neglected disease caused by intestinal nematodes of the genus,is endemic to tropical and subtropical areas such as *** methods only identify the genus,while DNA-molecular techniques are susceptible in Strongyloides *** study aims to determine the prevalence of dominant Strongyloides species among the population in Duc Hoa district,Long An,***:A cross-sectional study used 1190 stool specimens collected from July 2017 to November *** samples were transported within 2 h,stored at 2-8℃,and processed within 48 h for microscopy smear and culture at the Laboratory of Medical Parasitology,Pham Ngoc Thach University of Medicine(PNT).Then all positive samples with the above 2 methods were verified by real-time PCR ***-time PCR amplification was conducted at the Laboratory of Molecular Biology,***:Direct microscopy and modified Harada-Mori culture detected Strongyloides *** in 79/1190 sam-ples(6.6%).About 94.2%of the DNA samples were Strongyloides stercoralis,2.9%were co-infections with Strongy-loides ratti and ***,and 2.9%were patients with *** identity of 12/14 sequences was confirmed as *** with a high level of similarity(91.3%-100%)and over 98%for ***:DNA-molecular techniques and sequence analysis are highly suitable for identifying Strongyloides species isolated from stool *** is remarkable evidence of the presence of zoonosis *** disease in human,not just the known *** is likely to result in a certain proportion of people being infected by this animal-borne infectious pathogen.

关键词： Strongyloidiasis Strongyloides stercoralis Strongyloides ratti DNA-molecular techniques

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Zirconium metal organic framework for design of tetragonal rare earth-doped zirconia nanoparticles

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Journal of Rare Earths 2019年第11期37卷 1230-1236页

作者： lam Thi Kieu Giang Lukasz Marciniak Krzysztof Kamil Zur Dinh Manh Tien nguyen Vu nguyen Thanh Binh Tran Kim Anh Le Quoc Minh Institute of Materials Science Vietnam Academy of Science and Technology18 Hoang Quoc VietCau GiayHanoiViet Nam Graduate University of Science and Technology Vietnam Academy of Science and Technology18 Hoang Quoc VietCau GiayHanoiViet Nam Institute of Low Temperature and Structural Research Polish Academy of Sciencesul.Okolna 250-422 WroclawPoland Faculty of Mechanical Engineering Bialystok University of TechnologyWiejska 45C15-351 BialystokPoland Institute of Applied Physics and Scientific Instrument Vietnam Academy of Science and Technology18 Hoang Quoc VietCau GiayHanoiViet Nam Duy Tan University 03 Quang TrungDa NangViet Nam

Zirconium metal-organic frameworks ZrOBDC(where BDC=C6H4(COOH)2,terephthalic acid)doped and co-doped with rare earth ions Ln(ZrOBDC:Ln^3+,where Ln^3+=Eu3+and Tb^3+as well as Er^3+and Yb^3+)were used as precursors for the design of tetragonal rare earth doped zirconia nanoparticles(t-ZrO2:Ln^3+NPs)through annealing ***,characterization and luminescence properties of ZrOBDC:Ln^3+and ZrO2:Ln^3+NPs were *** as-obtained t-ZrO2:Ln^3+NPs have high purity with an average size of 20-30 *** luminescence spectra of ZrOBDC:Tb^3+and ZrOBDC:Eu3+display strong green and red emission at around 544 and 611 nm which correspond to 5D4→7F5 and 5D0→7F2 transitions of Tb^3+and Eu3+ions,*** green and red up-conversion emissions of ZrO2:Er^3+,Yb^3+NPs due to 2H11/2,4S3/2→4I15/2 and 4F9/2→4I15/2 transitions of the Er^3+ions are observed under 976 nm laser excitation.

关键词： Zirconium Rare earth ZrOBDC ZrOBDC:Ln3+ ZrO2:Ln3+ Up-conversion

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One-step hydrothermal synthesis of Sn-doped α-Fe_(2)O_(3) nanoparticles for enhanced photocatalytic degradation of Congo red

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Journal of Semiconductors 2022年第12期43卷 22-31页

作者： Van Nang lam Thi Bich Vu Quang Dat Do Thi Thanh Xuan Le Tien Dai nguyen T-Thanh-Bao nguyen Hoang Tung Do Thi Tu Oanh nguyen Department of Natural Sciences Hoa Lu UniversityNinh NhatNinh Binh CityViet Nam Institute of Theoretical and Applied Research Duy Tan UniversityHanoi 100000Viet Nam Faculty of Natural Sciences Duy Tan UniversityDa Nang 550000Vietnam Institute of Physics Vietnam Academy of Science and Technology10 Dao TanBa DinhHanoiVietnam Institute of Materials Science Vietnam Academy of Science and Technology18 Hoang Quoc VietCaugiayHanoiVietnam

We report on the synthesis of Sn-doped hematite nanoparticles(Sn-α-Fe_(2)O_(3) NPs)by the hydrothermal *** prepared Sn-α-Fe_(2)O_(3) NPs had a highly pure and well crystalline rhombohedral phase with an average particle size of 41.4 *** optical properties of as-synthesizedα-Fe_(2)O_(3) NPs show a higher bandgap energy(2.40-2.57 eV)than that of pure bulkα-Fe_(2)O_(3)(2.1 eV).By doping Sn intoα-Fe_(2)O_(3) NPs,the Sn-doped hematite was observed a redshift toward a long wavelength with in-creasing Sn concentration from 0%to 4.0%.The photocatalytic activity of Sn-dopedα-Fe_(2)O_(3) NPs was evaluated by Congo red(CR)dye *** degradation efficiency of CR dye using Sn-α-Fe_(2)O_(3) NPs catalyst is higher than that of pureα-Fe_(2)O_(3) *** highest degradation efficiency of CR dye was 97.8%using 2.5%Sn-dopedα-Fe_(2)O_(3) NPs catalyst under visible-light *** results suggest that the synthesized Sn-dopedα-Fe_(2)O_(3) nanoparticles might be a suitable approach to develop a photocatalytic degradation of toxic inorganic dye in wastewater.

关键词： α-Fe_(2)O_(3)nanoparticles Sn Congo red photocatalytic properties photodegradation

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Antibiofilm activity of alpha-mangostin loaded nanoparticles against Streptococcus mutans

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Asian Pacific Journal of Tropical Biomedicine 2020年第7期10卷 325-332页

作者： Phuong T.M.nguyen Minh T.H.nguyen Lien T.Quach Phuong T.M.nguyen lam L.nguyen Dong V.Quyen Institute of Biotechnology Vietnam Academy of Science and Technology18 Hoang Quoc Viet RoadHanoiVietnam Institute of Graduate University of Science and Technology Vietnam Academy of Science and Technology18 Hoang Quoc Viet RoadHanoiVietnam University of Science and Technology of Hanoi Vietnam Academy of Science and Technology18-Hoang Quoc Viet RoadCau GiayHanoiVietnam

Objective:To investigate the antibiofilm activity of alphamangostin(AMG)loaded nanoparticle(nano AMG)against dental caries pathogen Streptococcus ***:AMG was isolated from the peels of Garcinia mangostana *** silica gel columns and chemically analysed by high performance liquid chromatography and nuclear magnetic *** AMG was prepared using the solvent evaporation method combined with high-speed *** nanoparticles were characterized using dynamic light scattering,field emission scanning electron microscopy(FE-SEM)and Fourier transform infrared spectroscopy(FTIR).The toxicity of nano AMG in fibroblast NIH/3 T3 cell line was determined using MTT *** antibiofilm effect of nano AMG was determined through the evaluation of biofilm formation by Streptococcus mutans using a 96-well *** biomass was quantified using crystal *** viability was observed under confocal microscopy using LIVE/DEAD Bac Light ***,gene expression was determined by quantitative real-time PCR and membrane permeabilization activity by measuring the uptake of o-nitrophenol-β-***:Nano AMG size was in a range of 10-50 nm with a polydispersity index of<0.3 and zeta potential value of-35.2 m *** size and the incorporation of AMG in the nanoparticles were confirmed by FE-SEM and FTIR *** IC50 values of the test agents on NIH/3 T3 cells were(9.80±0.63)μg/m L for AMG and(8.70±0.81)μg/m L for nano AMG,while no toxicity was generated from excipients used to prepare *** the early stage of biofilm formation,treatment with 6.25μmol/L nano AMG caused a reduction in biofilm biomass up to 49.1%,compared to 33.4%for *** contrast,biofilms at the late stage were more resistant to the test *** 96μmol/L(=10×MIC),nano AMG reduced only 20.7%of biofilm biomass while AMG did not showany *** of gtf B and gtf C genes involved in biofilm formation were down-regulated 3.3 and 12.5 folds,res

关键词： Alpha-mangostin Nanoparticle Antibiofilm activity Streptococcus mutans

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Marker-Assisted Selection of Xa21 Conferring Resistance to Bacterial Leaf Blight in indica Rice Cultivar LT2

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Rice science 2018年第1期25卷 52-56页

作者： Hue Thi nguyen Quang Hong VU Tan Van MAI Thu Thi nguyen lam Duc VU Tung Thanh nguyen Long Viet nguyen Hien Thu Thi VU Hue Thi NONG Trung nguyen DINH Nakano TOSHITSUGU Liet Van VU Crop Research and Development Institute Vietnam National University of Agriculture Trau Qui Gia Lam Hanoi 10000 Vietnam Faculty of Agronomy Vietnam National University of Agriculture Trau Qui Gia Lam Hanoi 10000 Vietnam Faculty of Biotechnology Vietnam National University of Agriculture Trau Qui Gia Lam Hanoi 10000 Vietnam Faculty of Land Management Vietnam National University of Agriculture Trau Qui Gia Lam Hanoi 10000 Vietnam Japan International Cooperation Agency 16 Phan Chu Trinh Hoan Kiem Hanoi 10000 Vietnam

Bacterial leaf blight of rice (BLB), caused by Xanthomonas oryzae pv. oryzae, is one of the most destructive diseases in Asian rice fields. A high-quality rice variety, LT2, was used as the recipient ***21, which carries the Xa21 gene, was used as the donor parent. The resistance gene Xa21 was introduced into LT2 by marker-assisted backcrossing. Three Xoo races were used to inoculate the improved lines following the clipping method. Eleven BC_3F_3 lines carrying Xa21 were obtained based on molecular markers and agronomic performance. The 11 lines were then inoculated with the three Xoo races. All the 11 improved lines showed better resistance to BLB than the recipient parent LT2. Based on the level of resistance to BLB and their agronomic performance, five lines (BC_3F_3 5.***.5.1, BC_3F_3 5.***.5.12, BC_3F_3 8.***.6.44, BC_3F_3 9.***.4.1 and BC_3F_3 9.***.4.23) were selected as the most promising for commercial release. These improved lines could contribute to rice production in terms of food security.

关键词： rice backcrossing bacterial leaf blight marker-assisted selection

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High burden of hepatocellular carcinoma and viral hepatitis in Southern and Central Vietnam:Experience of a large tertiary referral center,2010 to 2016

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World Journal of Hepatology 2018年第1期10卷 116-123页

作者： Song-Huy nguyen-Dinh Albert Do Trang Ngoc Doan Pham Doan Y Dao Trinh nhu Nguy Moon S Chen Jr Liver Tumor DepartmentCho Ray HospitalHo Chi Minh City 700000Vietnam Department of Internal Medicine Yale UniversityNew HavenCT 06510United States School of Public Health University of IllinoisChicagoIL 60302United States Division of Digestive and Liver Diseases UT Southwestern Medical CenterDallasTX 75390United States Vietnam Viral Hepatitis Alliance Ho Chi Minh City 7000Vietnam Davis Comprehensive Cancer Center University of CaliforniaSacramentoCA 95817United States

AIM To examine the largest tertiary referral center in southern and central Vietnam from 2010 to 2016, evaluating epidemiological trends of hepatocellular carcinoma(HCC) and viral hepatitis B-C in this resource-limited *** We extracted data of patients receiving care from Cho Ray Hospital(Ho Chi Minh City), the largest oncology referral center in southern and central Vietnam, from 2010 to 2016. We collected information on patient age, gender, geographic distribution, and disease characteristics including disease stage, tumor biomarker levels [serum alpha-fetoprotein(AFP), AFP-L3 isoform percentage, and prothrombin induced by induced by vitamin K absence-Ⅱ], and serological testing for hepatitis B virus(HBV) and hepatitis C virus(HCV) *** Data from 24091 HCC patients were extracted, with sample demographics comprising mostly male(81.8%) and older age(however with 8.5% younger than 40 years old). This patient sample included a geographic catchment population of 56 million people(60% of the country's total population of 92.7 million), derived from 38 provinces and municipalities in Vietnam. Chronic HBV infection was found in 62.3% of cases, and chronic HCV infection in 26.0%. HBV and HCV co-infection was seen in 2.7%. Cirrhosis was found in an estimated 30% to 40% of cases. Nine percent of patients were not found to have chronic viral hepatitis. Twenty three point two percent of the patients had a normal AFP level. A total of 2199 patients were tested with AFP-L3 and PIVKA Ⅱ over two years, with 57.7% having elevated AFP-L3%, and 88.5% with elevated PIVKA Ⅱ levels. Over this 7-year period, the incidence of HCC increased, with a large proportion of cases(overall 40.8%) presenting initially an advanced stage, not amendable to surgical or locoregional *** HCC contributes significant health care burden in southern and central Vietnam, with increasing case volume over this seven-year period. Viral hepatitis likely explains this high

关键词： Hepatocellular carcinoma Hepatitis B virus Hepatitis C virus Alpha-fetoprotein

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Structure-based Comparative Analysis and Prediction of N-linked Glycosylation Sites in Evolutionarily Distant Eukaryotes

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Genomics, Proteomics & Bioinformatics 2013年第2期11卷 96-104页

作者： Phuc Vinh nguyen lam Radoslav Goldman Konstantinos Karagiannis Tejas Narsule Vahan Simonyan Valerii Soika Raja Mazumder Life Sciences Department Paris Diderot University Department of Biochemistry and Molecular Biology George Washington University Medical Center Department of Oncology Georgetown University Center for Biologics Evaluation and Research Food and Drug Administration

The asparagine-X-serine/threonine （NXS/T） motif, where X is any amino acid except proline, is the consensus motif for N-linked glycosylation. Significant numbers of high-resolution crystal structures of glycosylated proteins allow us to carry out structural analysis of the N-linked glycosylation sites （NGS）. Our analysis shows that there is enough structural information from diverse glycoproteins to allow the development of rules which can be used to predict NGS. A Python-based tool was developed to investigate asparagines implicated in N-glycosylation in five species： Homo sapiens, Mus musculus, Drosophila melanogaster, Arabidopsis thaliana and Saccharo- myees cerevisiae. Our analysis shows that 78 % of all asparagines of NXS/T motif involved in N-gly- cosylation are localized in the loop/turn conformation in the human proteome. Similar distribution was revealed for all the other species examined. Comparative analysis of the occurrence of NXS/T motifs not known to be glycosylated and their reverse sequence （S/TXN） shows a similar distribu- tion across the secondary structural elements, indicating that the NXS/T motif in itself is not bio- logically relevant. Based on our analysis, we have defined rules to determine NGS. Using machine learning methods based on these rules we can predict with 93% accuracy if a particular site will be glycosylated. If structural information is not available the tool uses structural prediction results resulting in 74% accuracy. The tool was used to identify glycosylation sites in 108 human proteins with structures and 2247 proteins without structures that have acquired NXS/T site/s due to non-synonymous variation. The tool, Structure Feature Analysis Tool （SFAT）, is freely available to the public at http：//***/tools/sfat.

关键词： N-linked glycosylation Gain and loss of glycosyla-tion nsSNP nsSNV Variation

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