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Process of establishing design requirements and selecting alternative configurations for conceptual design of a VLA

Chinese Journal of Aeronautics 2017年第2期30卷 738-751页

作者： Bo-Young Bae Sangho Kim Jae-Woo Lee nhu van nguyen Bong-Cheul Chung Department of Aerospaee Information Engineering Konkuk University Seoul 143-701 Republic of Korea Konkuk Aerospace Design Airworthiness Research Institute Konkuk University Seoul 143-701 Republic of Korea

In this study,a process for establishing design requirements and selecting alternative configurations for the conceptual phase of aircraft design has been *** proposed process uses system-engineering-based requirement-analysis techniques such as objective tree,analytic hierarchy process,and quality function deployment to establish logical and quantitative ***,in order to perform a logical selection of alternative aircraft configurations,it uses advanced decision-making methods such as morphological matrix and technique for order preference by similarity to the ideal *** addition,a preliminary sizing tool has been developed to check the feasibility of the established performance requirements and to evaluate the flight performance of the selected *** present process has been applied for a two-seater very light aircraft（VLA）,resulting in a set of tentative design requirements and two families of VLA configurations：a high-wing configuration and a low-wing *** resulting set of design requirements consists of three categories：customer requirements,certification requirements,and performance *** performance requirements include two mission requirements for the flight range and the endurance by reflecting the customer *** flight performances of the two configuration families were evaluated using the sizing tool developed and the low-wing configuration with conventional tails was selected as the best baseline configuration for the VLA.

关键词： Aircraft configuration Conceptional design Design requirements Requirement analysis Very light aircraft (VLA)

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Adaptive optimal control system design for semi-active suspension system by supposing variable parameters under exogenous road disturbance

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Control Theory and Technology 2025年第1期23卷 64-73页

作者： Viet nguyen Hoang Feiqi Deng Chi nguyen van School of Automation Science and Engineering South China University of TechnologyGuangzhou510640GuangdongChina Thai nguyen University of Technology Thai Nguyen CityVietnam

This article presents an adaptive optimal control method for a semi-active suspension *** model of the suspension system is built,in which the components of uncertain parameters and exogenous disturbance are *** adaptive optimal control law consists of the sum of the optimal control component and the adaptive control ***,the optimal control law is designed for the model of the suspension system after ignoring the components of uncertain parameters and exogenous disturbance caused by the road *** optimal control law expresses the desired dynamic characteristics of the suspension ***,the adaptive component is designed with the purpose of compensating for the effects caused by uncertain parameters and exogenous disturbance caused by the road surface;the adaptive component has adaptive parameter rules to estimate uncertain parameters and exogenous *** exogenous disturbances are eliminated,the system responds with an optimal controller *** separating theoretically the dynamic of a semi-active suspension system,this solution allows the design of two separate controllers easily and has reduced the computational burden and the use of too many tools,thus allowing for more convenient hardware *** simulation results also show the effectiveness of damping oscillations of the proposed solution in this article.

关键词： Quarter car suspension system Semi-active suspension Adaptive control Optimal control Linear-quadratic regulator Exogenous disturbance

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Landslide Susceptibility Mapping Using RBFN-Based Ensemble Machine Learning Models

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Computer Modeling in Engineering & Sciences 2025年第1期142卷 467-500页

作者： Duc-Dam nguyen nguyen Viet Tiep Quynh-Anh Thi Bui Hiep van Le Indra Prakash Romulus Costache Manish Pandey Binh Thai Pham Faculty of Civil Engineering University of Transport TechnologyThanh XuanHa Noi100000Vietnam Faculty of Hydraulic Engineering Hanoi University of Civil EngineeringHa Noi100000Vietnam DDG(R)Geological Survey of India Gandhinagar382010India Research Institute of the University of Bucharest Bucharest050663Romania National Institute of Hydrology and Water Management Bucharest013686Romania Department of Civil Engineering Transilvania University of BrasovBrasov500152Romania Danube Delta National Institute for Research and Development Tulcea820112Romania Marwadi University Research Center(MURC) Marwadi UniversityRajkotGujaratBharat360003India Department of Civil Engineering Faculty of Engineering&TechnologyMarwadi UniversityRajkotGujaratBharat360003India

This study was aimed to prepare landslide susceptibility maps for the Pithoragarh district in Uttarakhand,India,using advanced ensemble models that combined Radial Basis Function Networks(RBFN)with three ensemble learning techniques:DAGGING(DG),MULTIBOOST(MB),and ADABOOST(AB).This combination resulted in three distinct ensemble models:DG-RBFN,MB-RBFN,and ***,a traditional weighted method,Information Value(IV),and a benchmark machine learning(ML)model,Multilayer Perceptron Neural Network(MLP),were employed for comparison and *** models were developed using ten landslide conditioning factors,which included slope,aspect,elevation,curvature,land cover,geomorphology,overburden depth,lithology,distance to rivers and distance to *** factors were instrumental in predicting the output variable,which was the probability of landslide *** analysis of the models’performance indicated that the DG-RBFN model,with an Area Under ROC Curve(AUC)of 0.931,outperformed the other *** AB-RBFN model achieved an AUC of 0.929,the MB-RBFN model had an AUC of 0.913,and the MLP model recorded an AUC of *** results suggest that the advanced ensemble ML model DG-RBFN was more accurate than traditional statistical model,single MLP model,and other ensemble models in preparing trustworthy landslide susceptibility maps,thereby enhancing land use planning and decision-making.

关键词： Landslide susceptibility map spatial analysis ensemble modelling information values(IV)

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The Theory of the Extended Electron (Anti-Particles of Dirac and Majorana)

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Journal of High Energy Physics, Gravitation and Cosmology 2025年第1期11卷 183-202页

作者： Hoa van nguyen Toronto Canada

This theory proposes an extended model of the electron based on the image of the screened electron in the concept of vacuum polarization of QED. The extended electron consists of a negatively charged core −q0which is surrounded by an assembly (an aggregation) of tiny static electric dipoles −q,+q. When subjected to an external field, electromagnetic forces are produced on these point charges to give rise to various properties of the electron. Three major properties of the electron that will be explored in this theory are: 1) the effective electric charge of the electron;2) the mechanism of the spin of the electron;3) the mechanism of radiation of the electron. The investigation of these properties leads to various innovative explanations for the generation of anti-particle, the orbital of the electron, the strong nuclear forces between nucleons … Other topics are also listed in the following content.

关键词： The Extended Model of the Electron The Core (-q0) Static Electric Dipoles (-q +q) The Effective Electric Charge Q the Permittivity ε The Permeability μ

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Prediction of Shear Bond Strength of Asphalt Concrete Pavement Using Machine Learning Models and Grid Search Optimization Technique

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Computer Modeling in Engineering & Sciences 2025年第1期142卷 691-712页

作者： Quynh-Anh Thi Bui Dam Duc nguyen Hiep van Le Indra Prakash Binh Thai Pham Civil Engineering Department University of Transport Technology54 Trieu KhucThanh XuanHanoi100000Vietnam DDG(R)Geological Survey of India Gandhinagar382010India

Determination of Shear Bond strength(SBS)at interlayer of double-layer asphalt concrete is crucial in flexible pavement *** study used three Machine Learning(ML)models,including K-Nearest Neighbors(KNN),Extra Trees(ET),and Light Gradient Boosting Machine(LGBM),to predict SBS based on easily determinable input ***,the Grid Search technique was employed for hyper-parameter tuning of the ML models,and cross-validation and learning curve analysis were used for training the *** models were built on a database of 240 experimental results and three input variables:temperature,normal pressure,and tack coat *** validation was performed using three statistical criteria:the coefficient of determination(R2),the Root Mean Square Error(RMSE),and the mean absolute error(MAE).Additionally,SHAP analysis was also used to validate the importance of the input variables in the prediction of the *** show that these models accurately predict SBS,with LGBM providing outstanding ***(Shapley Additive explanation)analysis for LGBM indicates that temperature is the most influential factor on ***,the proposed ML models can quickly and accurately predict SBS between two layers of asphalt concrete,serving practical applications in flexible pavement structure design.

关键词： Shear bond asphalt pavement grid search optimization machine learning

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Optimization of the in Vitro Fertilization System in Cỏ Goat Oocytes

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Open Journal of Animal Sciences 2025年第1期15卷 39-50页

作者： van Khanh nguyen Huong Thi Thu Vu Au Thi Hoang Yen Thi Kim Pham Dat van Le Quan Xuan Huu Lan Anh Thi nguyen Huong Le Thi nguyen Lan Doan Pham Key Laboratory of Animal Cell Biotechnology National Institute of Animal Sciences Hanoi Vietnam

This study aimed to optimization of the in vitro fertilization system in Cỏ goat oocytes to achieve the maximum possible blastocyst development rate. In Experiment 1, we assessed the effects of IVF media on the in vitro fertilization of Cỏ goat oocytes. There was no significant difference in the cleavage, blastocyst, or hatching rates between TALP-Fert and BO-IVF media. Experiment 2 was performed to assess the concentration of sperm in the in vitro fertilization of Cỏ goat oocytes. The matured Cỏ goat oocytes were fertilized in BO-IVF for four sperm concentrations: 5 × 105, 1 × 106, 2 × 106 and 3 × 106 sperm/ml. The blastocyst rate of 2 × 106 sperm/ml and 3 × 106 sperm/ml groups was higher than that of 5 × 105 sperm/ml and 1 × 106 sperm/ml groups (P Experiment 3 was performed to assess the IVF duration on the in vitro fertilization of Cỏ goat oocytes. The matured Cỏ goat oocytes were fertilized in BO-IVF with sperm concentration of 3 × 106 sperm/ml for 18, 20, 22 and 24 h. The cleavage, blastocyst, and hatching blastocyst rates of 18 h group were lower than those of 20, 22 and 24 h groups (P 0.05). In conclusion, the matured Cỏ goat oocytes were fertilized in BO-IVF with sperm concentration of 3 × 106 sperm/ml for 20 hours, which is suitable for the in vitro Cỏ goat embryo production.

关键词： Cỏ Goat Oocytes In Vitro Fertilizaition Media In Vitro Fertilizaition Duration Sperm Concentration In Vitro Embryos

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Numerical investigation of the influence of casting techniques on fiber orientation distribution in ECC

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Frontiers of Structural and Civil Engineering 2022年第11期16卷 1424-1435页

作者： Chung nguyen van Hai TRAN THANH Thuc nhu nguyen Jianchun LI Faculty of Civil Engineering Ho Chi Minh City University of Technology and EducationHo Chi Minh 721400Vietnam School of Civil and Environmental Engineering University of Technology SydneySydneyNSW 2007Australia School of Civil Engineering Hue Industrial CollegeHue 49120Vietnam

Engineered cementitious composites(ECC),also known as bendable concrete,were developed based on engineering the interactions between fibers and cementitious *** orientation of fibers,in this regard,is one of the major factors influencing the ductile behavior of this *** this study,fiber orientation distributions in ECC beams influenced by different casting techniques are evaluated via numerical modeling of the casting *** casting directions and two casting positions of the funnel outlet with beam specimens are modeled using a particle-based smoothed particle hydrodynamics(SPH)*** this SPH approach,fresh mortar and fiber are discretized by separated mortar and fiber particles,which smoothly interact in the computational domain of *** movement of fiber particles is monitored during the casting ***,the fiber orientations at different sections of specimens are determined after the fresh ECC stops flowing in the *** simulation results show a significant impact of the casting direction on fiber orientation distributions along the longitudinal wall of beams,which eventually influence the flexural strength of *** addition,casting positions show negligible influences on the orientation distribution of fibers in the short ECC beam,except under the pouring position.

关键词： ECC fiber orientation distribution casting direction casting position

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Hepatic eosinophilic pseudotumor due to Fasciola hepatica infection mimicking intrahepatic cholangiocarcinoma: A case report

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World Journal of Hepatology 2025年第1期17卷 158-166页

作者： Kim-Long Le Minh-Quang Tran Tri-Nhan Pham nhu Ngoc-Quynh Duong Thien Thuan Dinh nguyen-Khoi Le Department of Surgery Pham Ngoc Thach University of MedicineHo Chi Minh 07000Viet Nam Department of Hepato-Pancreato-Biliary Nhan Dan Gia Dinh HospitalHo Chi Minh 07000Viet Nam Department of Surgery District 4 HospitalHo Chi Minh 07000Viet Nam

BACKGROUND Hepatic eosinophilic pseudotumor(HEPT)is a rare condition that mimics ma-lignant hepatic tumors,posing significant diagnostic *** case report highlights the importance of considering parasitic infections like Fasciola hepatica(***)in the differential diagnosis of hepatic masses,especially in endemic regions,to prevent unnecessary *** SUMMARY A 40-year-old female presented with a 1-month history of epigastric pain and significant weight *** revealed a hepatic mass,initially misdiagnosed as intrahepatic *** results showed marked eosinophilia,and histopathological examination confirmed significant eosinophilic infiltration without *** testing identified *** *** patient was treated with a single dose of triclabendazole,leading to complete symptom resolution and normalization of hepatic imaging findings within *** HEPT due to *** can closely mimic malignancy;timely antiparasitic treat-ment is crucial for resolution.

关键词： Hepatic eosinophilic pseudotumor Eosinophilic liver infiltration Eosinophilia Fascioliasis Fasciola hepatica Eosinophilic pseudotumor Parasitic infection Hepatic abscess Triclabendazole Case report

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Predictive value of tacrolimus concentration/dose ratio in first posttransplant week for CYP3A5-polymorphism in kidney-transplant recipients

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World Journal of Transplantation 2025年第2期15卷 197-204页

作者： Pham-Thai Dung Hoang-Xuan Su nguyen-Chi Tue nguyen-Huu Ben nguyen-Minh Phuong Tuan-Ngoc Tran Phan-Ba Nghia Diem-Thi van nguyen Thi-Thuy Dung Hoang-Trung Vinh Lionel Rostaing Pham-Quoc Toan Center of Critical Care Medicine Emergency and Clinical ToxicologyMilitary HospitalHanoï100000Viet Nam Institute of Biomedicine and Pharmacy Vietnam Military Medical UniversityHanoï100000Viet Nam Department of Post-Transplant Intensive Care and Treatment Center of Organ Transplantation-Military HospitalHanoï100000Viet Nam Department of Occupational Medicine Vietnam Military Medical UniversityHanoï100000Viet Nam Department of Military Medical Command and Organization Vietnam Military Medical UniversityHanoï100000Viet Nam Department of Nephrology and Dialysis Military HospitalHanoï100000Viet Nam Department of Nephrology HemodialysisApheresisand Kidney TransplantationGrenoble University HospitalGrenoble 38043Auvergne-Rhone-AlpesFrance

BACKGROUND Tacrolimus(TAC)is metabolized primarily by the CYP3A-encoded enzyme family(CYP3A4,CYP3A5,and CYP3A7).Individuals expressing the CYP3A51 allele are considered fast metabolizers and generally require higher TAC doses to reach therapeutic *** To evaluate the predictive value of the TAC concentration-to-dose(C0/D)ratio for identifying CYP3A5 poly-morphisms in renal transplant *** Eighty-six de novo kidney transplant recipients with TAC-based immunosuppression from the Department of Nephrology and Dialysis at Military Hospital 103(Hanoi,Vietnam)were included in this retrospective *** samples were collected within the first week post-transplantation to monitor TAC levels and to perform genotyping for CYP3A5 genetic *** The CYP3A53/3 genotype was identified in 37 patients(43%),CYP3A51/3 in 40 patients(46.5%),and CYP3A51/1 in 9 patients(10.5%).Patients carrying the CYP3A51/3 or CYP3A51/1 genotype,classified as fast metabolizers(CYP3A5 expressers),had significantly lower TAC C0 concentrations and C0/D ratios compared to slow meta-bolizers(CYP3A53/3 genotype)at multiple time points during follow-up(all P<0.001).Notably,the TAC C0/D ratio obtained on day 1(0.91)was shown to predict CYP3A5 polymorphism with a sensitivity of 84.6%and a specificity of 84.6%.CONCLUSION This study demonstrates that the TAC C0/D ratio provides a reliable predictive value for CYP3A5 polymorphisms,which can be used to individualize TAC dosing in renal transplant recipients in Vietnam and other low-income countries.

关键词： Tacrolimus CYP3A5 Renal transplant recipient Concentration-to-dose Kidney transplant

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Persistent challenges in the diagnosis of acute pancreatitis due to primary hyperparathyroidism during pregnancy

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World Journal of Gastroenterology 2025年第7期31卷 1-9页

作者： Thang Viet Luong Linh Duy Le Nam van Duc nguyen Hai nguyen Ngoc Dang Department of Internal Medicine University of Medicine and PharmacyHue UniversityHue 530000Viet Nam Faculty of Medicine Duy Tan UniversityDa Nang 550000Viet Nam

In this manuscript,we provide critical commentary on the systematic review by Augustin et al,which investigated acute pancreatitis induced by primary hyperparathyroidism during *** this is an infrequent complication,it poses severe risks to both maternal and fetal *** to its infrequent occurrence in clinical practice,this review is based on an analysis of individual case reports over the past 55 *** this is not the first study to utilize this sampling method for primary hyperparathyroidism-induced acute pancreatitis,it is unique in that it has a sufficiently large sample size with statistically significant *** discussion focuses on the diagnostic challenges associated with this condition,which are grounded in the mechanisms of parathyroid hormone secretion and variations in serum calcium *** also address the limitations of the current review and suggest potential strategies to increase diagnostic accuracy and improve health outcomes for both mothers and fetuses during pregnancy.

关键词： Primary hyperparathyroidism Acute pancreatitis Pregnancy Diagnostic algorithm Parathyroid hormone Systematic review

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