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Determination of the Administration Routes,Doses and Appropriate Age to Vaccinate With Ornitin Triple Vaccine For Cross-breed Colored Broilers in Vietnam

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Veterinary Science Research 2019年第2期1卷 1-9页

作者： nguyen Manh Ho Bui Ngoc xuan Ha Le thi Kim Tuyen Le thi Anh Thu Le Thanh Hien Quach Tuyet Anh Faculty of Animal Science and Veterinary Medicine Nong Lam UniversityHo Chi Minh CityVietnam

The study was to determine the appropriate dose and administration route of Ornitin Triple vaccine in cross-breed coloured broilers in Vietnam by evaluating the antibody titer against Ornithobacterium rhinotracheale(ORT)and local reactions at injection sites on chickens after *** study was divided into 2 *** trials were designed with 3 vaccine dose groups:0.0ml(control group),0.25ml and 0.5ml and 2 different administration routes:subcutaneous at neck(SC)and intramuscular at breast(IM)*** result showed that,no statistically significant difference was found between antibody titer of two administration routes as well as 2 vaccine doses until *** reactions at the injection sites of IM route was less severe than SC at neck and in higher dose would produce a more severe swelling *** weight gain was found to have a slight decrease in the vaccinated groups within 2 weeks after vaccination,however,no statistically significant difference was found in later stage(P>0.05).In conclusion,Ornitin Triple can be used to vaccinate by IM with the dose of 0.25ml for coloured broilers at early age(3-week-old),or 0.5ml for older birds and should be careful for some reactions at the injection sites.

关键词： ORT disease swelling reaction titer IDEXX bacteria vaccine

Real-world Effectiveness and Tolerability of Interferonfree Direct-acting Antiviral for 15,849 Patients with Chronic Hepatitis C:A Multinational Cohort Study

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Journal of Clinical and Translational Hepatology 2024年第7期12卷 646-658页

作者： Fanpu Ji Sally Tran Eiichi Ogawa Chung-Feng Huang Takanori Suzuki Yu Jun Wong Hidenori Toyoda Dae Won Jun Liu Li Haruki Uojima Akito Nozaki Makoto Chuma Cheng-Hao Tseng Yao-Chun Hsu Masatoshi Ishigami Takashi Honda Masanori Atsukawa Hiroaki Haga Masaru Enomoto Huy Trinh Carmen Monica Preda Phillip Vutien Charles Landis Dong Hyun Lee Tsunamasa Watanabe Hirokazu Takahashi Hiroshi Abe Akira Asai Yuichiro Eguchi Jie Li Xiaozhong Wang Jia Li Junping Liu Jing Liang Carla Pui-Mei Lam Rui Huang Qing Ye Hongying Pan Jiajie Zhang Dachuan Cai Qi Wang Daniel Q.Huang Grace Wong Vincent Wai-Sun Wong Junyi Li Son Do Norihiro Furusyo Makoto Nakamuta Hideyuki Nomura Eiji Kajiwara Eileen L.Yoon Sang Bong Ahn Koichi Azuma Kazufumi Dohmen Jihyun An Do Seon Song Hyun Chin Cho Akira Kawano Toshimasa Koyanagi Aritsune Ooho Takeaki Satoh Kazuhiro Takahashi Ming-Lun Yeh Pei-Chien Tsai Satoshi Yasuda Yunyu Zhao Yishan Liu Tomomi Okubo Norio Itokawa Mi Jung Jun Toru Ishikawa Koichi Takaguchi Tomonori Senoh Mingyuan Zhang Changqing Zhao Raluca Ioana Alecu Wei xuan Tay Pooja Devan Joanne Kimiko Liu Ritsuzo Kozuka Elena Vargas-Accarino Ai-thien Do Mayumi Maeda Wan-Long Chuang Jee-Fu Huang Chia-Yen Dai Ramsey Cheung Maria Buti Junqi Niu Wen Xie Hong Ren Seng Gee Lim Chao Wu Man-Fung Yuen Jia Shang Qiang Zhu Yoshiyuki Ueno Yasuhito Tanaka Jun Hayashi Ming-Lung Yu Mindie H.nguyen Department of Infectious Diseases The Second Affiliated Hospital of Xi’an Jiaotong UniversityXi’anShaanxiChina Division of Gastroenterology and Hepatology Department of MedicineStanford University Medical CenterPalo AltoCAUSA Department of General Internal Medicine Kyushu University HospitalFukuokaJapan Hepatobiliary Division Department of Internal MedicineKaohsiung Medical University HospitalKaohsiung Hepatitis Research Center College of Medicine and Center for Liquid Biopsy and Cohort ResearchKaohsiung Medical UniversityKaohsiung Department of Gastroenterology and Metabolism Nagoya City University Graduate School of Medical SciencesNagoyaJapan Gastroenterology&Hepatology Changi General HospitalSinghealthSingapore Singhealth Duke-NUS Medicine Academic Clinical Program Singapore Department of Gastroenterology Ogaki Municipal HospitalOgakiJapan Department of Internal Medicine Hanyang UniversityCollege of MedicineSeoulKorea Hanyang Institute of Bioscience and Biotechnology Hanyang UniversitySeoulKorea Department of Hepatology The Third People's Hospital of Kunming CityKunmingYunnanChina Department of Gastroenterology Internal MedicineKitasato University School of MedicineSagamiharaJapan Gastroenterological Center Yokohama City University Medical CenterYokohamaJapan Division of Gastroenterology and Hepatology Department of Internal MedicineE-Da Cancer HospitalKaohsiung Department of Gastroenterology and Hepatology Nagoya University Graduate School of MedicineNagoyaJapan Division of Gastroenterology and Hepatology Nippon Medical SchoolTokyoJapan Department of Gastroenterology Yamagata University Faculty of MedicineYamagataJapan Department of Transfusion Medicine and Department of Hepatology Osaka Metropolitan University Graduate School of MedicineOsakaJapan San Jose Gastroenterology San JoseCAUSA Gastroenterology&Hepatology Department Clinic Fundeni InstituteBucharestRomania Division of Gastroenterology and Hepatology University of WashingtonSeattleWAUSA Department of

Background and Aims:As practice patterns and hepatitis C virus(HCV)genotypes(GT)vary geographically,a global real-world study from both East and West covering all GTs can help inform practice policy toward the 2030 HCV elimination *** study aimed to assess the effectiveness and tolerability of DAA treatment in routine clinical practice in a multinational cohort for patients infected with all HCV GTs,focusing on GT3 and ***:We analyzed the sustained virological response(SVR12)of 15,849 chronic hepatitis C patients from 39 Real-World Evidence from the Asia Liver Consortium for HCV clinical sites in Asia Pacific,North America,and Europe between 07/01/2014–07/01/***:The mean age was 62±13 years,with 49.6%*** demographic breakdown was 91.1%Asian(52.9%Japanese,25.7%Chinese/Taiwan residents,5.4%Korean,3.3%Malaysian,and 2.9%Vietnamese),6.4%White,1.3%Hispanic/Latino,and 1%Black/***,34.8%had cirrhosis,8.6%had hepatocellular carcinoma(HCC),and 24.9%were treatment-experienced(20.7%with interferon,4.3%with direct-acting antivirals).The largest group was GT1(10,246[64.6%]),followed by GT2(3,686[23.2%]),GT3(1,151[7.2%]),GT6(457[2.8%]),GT4(47[0.3%]),GT5(1[0.006%]),and untyped GTs(261[1.6%]).The overall SVR12 was 96.9%,with rates over 95%for GT1/2/3/6 but 91.5%for ***12 for GT3 was 95.1%overall,98.2%for GT3a,and 94.0%for ***12 was 98.3%overall for GT6,lower for patients with cirrhosis and treatment-experienced(TE)(93.8%)but≥97.5%for tretment-naive patients regardless of cirrhosis *** multivariable analysis,advanced age,prior treatment failure,cirrhosis,active HCC,and GT3/4 were independent predictors of lower SVR12,while being Asian was a significant predictor of achieving ***:In this diverse multinational realworld cohort of patients with various GTs,the overall cure rate was 96.9%,despite large numbers of patients with cirrhosis,HCC,TE,and GT3/***12 for GT3/6 with cirrhosis and TE was lower but st

关键词： Hepatitis C virus Liver cirrhosis Hepatocellular carcinoma Genotype DAA REAL-C

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越南基巧红宝石中的包裹体及其成因

宝石和宝石学杂志 2004年第3期6卷 40-42页

作者： Pham Van Long Hoang Quang Vinh nguyen xuan Nghia 闫晨 CentreforGemandGoldResearchandIdentification HanoiVietnam InstituteofGeologicalSciences NCNSTHanoiVietnam InstituteofMaterialsScience NCNSTHanoiVietnam 不详

展示了对越南基巧红宝石中包裹体的研究成果。用光学显微镜检测了这些包裹体的特征。采用拉曼散射法和扫描电子探针分析了包裹体的成分。在该类红宝石中发现了锐钛矿、红柱石、钙长石、磷灰石、黑云母、一水软铝石、板钛矿、方解石、刚... 详细信息

展示了对越南基巧红宝石中包裹体的研究成果。用光学显微镜检测了这些包裹体的特征。采用拉曼散射法和扫描电子探针分析了包裹体的成分。在该类红宝石中发现了锐钛矿、红柱石、钙长石、磷灰石、黑云母、一水软铝石、板钛矿、方解石、刚玉、硬水铝石、白云石、石墨、珍珠云母、白云母、金云母、黄铁矿、金红石、锆石、黝帘石包裹体组合。描述了该类红宝石多相包裹体中气-液相与负晶的成分,讨论了主晶红宝石的形成条件。

关键词：包裹体红宝石矿物组合成因越南

基于灰云模型的城市道路交叉口交通冲突严重性研究

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交通运输工程与信息学报 2019年第3期17卷 162-169页

作者：王春勤牟瑞芳阮黄山西南交通大学交通运输与物流学院成都611756 越南交通运输大学越南河内

城市道路是城市道路网中的重要节点,也是交通事故的多发点。因其交通组成和交通特性复杂,易造成车辆相互干扰和交通冲突。交通冲突严重性与交通事故发生可能性和严重性之间具有密切关系。因此,分析交通冲突严重性对于提高道路交叉口安... 详细信息

城市道路是城市道路网中的重要节点,也是交通事故的多发点。因其交通组成和交通特性复杂,易造成车辆相互干扰和交通冲突。交通冲突严重性与交通事故发生可能性和严重性之间具有密切关系。因此,分析交通冲突严重性对于提高道路交叉口安全性具有实际意义。本文采用早高峰、平峰以及晚高峰三个时段的交通冲突数与混合当量交通量的比值(TC/MPCU)作为评价指标,并利用灰云模型建立交叉口交通冲突严重性分级评价方法,针对8个相似交叉口进行实例应用,结果表明该方法评价所得结果与交叉口实际交通状况接近,说明该方法有效可行。

关键词：灰云模型交通冲突交叉口严重性分级

A novel over-sampling method and its application to miRNA prediction

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Journal of Biomedical Science and Engineering 2013年第2期6卷 236-248页

作者： xuan Tho Dang Osamu Hirose Thammakorn Saethang Vu Anh Tran Lan Anh T. nguyen Tu Kien T. Le Mamoru Kubo Yoichi Yamada Kenji Satou Graduate School of Natural Science and Technology Kanazawa University Kanazawa Japan Institute of Science and Engineering Kanazawa University Kanazawa Japan

MicroRNAs (miRNAs) are short (~22nt) non-coding RNAs that play an indispensable role in gene regulation of many biological processes. Most of current computational, comparative, and non-comparative methods commonly classify human precursor micro- RNA (pre-miRNA) hairpins from both genome pseudo hairpins and other non-coding RNAs (ncRNAs). Although there were a few approaches achieving promising results in applying class imbalance learning methods, this issue has still not solved completely and successfully yet by the existing methods because of imbalanced class distribution in the datasets. For example, SMOTE is a famous and general over-sampling method addressing this problem, however in some cases it cannot improve or sometimes reduces classification performance. Therefore, we developed a novel over-sampling method named incre-mental- SMOTE to distinguish human pre-miRNA hairpins from both genome pseudo hairpins and other ncRNAs. Experimental results on pre-miRNA datasets from Batuwita et al. showed that our method achieved better Sensitivity and G-mean than the control (no over- sampling), SMOTE, and several successsors of modified SMOTE including safe-level-SMOTE and border-line-SMOTE. In addition, we also applied the novel method to five imbalanced benchmark datasets from UCI Machine Learning Repository and achieved improvements in Sensitivity and G-mean. These results suggest that our method outperforms SMOTE and several successors of it in various biomedical classification problems including miRNA classification.

关键词： Imbalanced Dataset Over-Sampling SMOTE miRNA Classification

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日本的下一步--秘密移民政策

商业周刊（中文版） 2019年第6期 31-33页

作者： Jason Clenfield Yuko Takeo Pavel Alpeyev xuan Ouynh nguyen 永年(译) 不详

换成是在几年前,杉原尚辅(Naosuke Sugihara)如今经营的业务都是无法想象的。自2016年以来,他一直在为日本的酒店、疗养院和食品加工厂的低技能工作岗位招聘菲律宾人、越南人和中国人。尽管该国长期以来一直抵制聘用外国人,但2019年,杉... 详细信息

换成是在几年前,杉原尚辅(Naosuke Sugihara)如今经营的业务都是无法想象的。自2016年以来,他一直在为日本的酒店、疗养院和食品加工厂的低技能工作岗位招聘菲律宾人、越南人和中国人。尽管该国长期以来一直抵制聘用外国人,但2019年,杉原的公司Gaijinbank有望提供500多名工人,大约是2018年的两倍(gaijin在日语中意为“外人”)。他说:“这只是一个开始,一股大浪潮即将到来。”

关键词：移民政策日本食品加工厂菲律宾人岗位招聘 “外人” 疗养院中国人

以固态核径迹探测器方法为基础的铀矿勘探钻孔测井技术

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国外铀金地质 1993年第1期10卷 64-68页

作者： xuan Thang nguyen Anh Tuan Doan Duc Tien Hoang 李珍媛核工业北京地质研究院 100029

根据不同介质中氡迁移的不同机制,本文作者研究了一种新的铀矿勘探钻孔测井技术。这种新技术参照了其他钻孔测井方法,其优点是:有可能找到钻孔所需深度的答案.在空气和水中,氡迁移的2种形式一直被用来测定氡分布。对这2种研究的形式开... 详细信息

根据不同介质中氡迁移的不同机制,本文作者研究了一种新的铀矿勘探钻孔测井技术。这种新技术参照了其他钻孔测井方法,其优点是:有可能找到钻孔所需深度的答案.在空气和水中,氡迁移的2种形式一直被用来测定氡分布。对这2种研究的形式开发了计算机程序,以期从理论上对氡径迹密度(作为钻孔深度的一个函数)进行计算。本文将理论上与实际上所获得的数据进行了比较.

关键词：氡迁移钻孔测井铀矿床勘探

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东南亚断裂构造的演化(英文)

大地测量与地球动力学 2005年第1期25卷 51-60页

作者：高庭朝阮友宣黎文勇范南雄 Mai xuan Bach Thai Anh Tuan 越南国家自然科学与技术中心地球物理研究所

本研究项目是采用诸如地质学解释、影像判读和地球物理探测等多种方法相结合进行的。在所得结果的基础上参考了越南国内外同行的一些资料编制了东南亚、越南及邻区的断裂构造图,其比例尺分别为1∶4百万和1∶1百万。分析所得结果... 详细信息

本研究项目是采用诸如地质学解释、影像判读和地球物理探测等多种方法相结合进行的。在所得结果的基础上参考了越南国内外同行的一些资料编制了东南亚、越南及邻区的断裂构造图,其比例尺分别为1∶4百万和1∶1百万。分析所得结果显示出东南亚断裂构造演化的下列情况: 1)在现今地质结构方面　东南亚是欧亚岩石圈板块的东南部分,由一条消减带围绕,这条消减带的伸展从 Myanmer开始,通过Nicobar,JavaTimor直到东菲律宾。东南亚被SongHong(即红河)断裂,ThreePagodas断裂和Hainam Natuna断裂等2级断裂系统分成3个微板块。 2)在早新生代,东南亚是分为5个微板块的。它们的分界断裂中有2个一级断裂(中央东海扩张带和Lupar Kuching消减带)和3个二级断裂(即上述3个)。 3)上述绝大多数二和三级断裂从晚新生代起活化且继承了从早新生代即已发生和发展了的二、三级断裂,但在某些条件下,运动方向却完全变成了相反,尤其是走滑运动的方向。我们的研究结果表明:在这一地区内,盆地、隆起、岩浆侵入、褶皱和局部断裂等构造的形成都取决于这些沿着一、二级走滑断裂的微板块运动。

关键词：断裂构造消减带走滑断裂走滑运动板块运动岩石圈演化东南亚中央继承

Predicting residue contacts for protein-protein interactions by integration of multiple information

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Journal of Biomedical Science and Engineering 2014年第1期7卷 28-37页

作者： Tu Kien T. Le Osamu Hirose Vu Anh Tran Thammakorn Saethang Lan Anh T. nguyen xuan Tho Dang Duc Luu Ngo Mamoru Kubo Yoichi Yamada Kenji Satou Graduate School of Natural Science and Technology Kanazawa University Kanazawa Japan Institute of Science and Engineering Kanazawa University Kanazawa Japan

Detailed knowledge of interfacial region between interacting proteins is not only helpful in annotating function for proteins, but also very important for structure-based drug design and disease treatment. However, this is one of the most difficult tasks and current methods are constrained by some factors. In this study, we developed a new method to predict residue-residue contacts of two interacting protein domains by integrating information about evolutionary couplings andamino acid pairwise contact potentials, as well as domain-domain interaction interfaces. The experimental results showed that our proposed method outperformed the previous method with the same datasets. Moreover, the method promises an improvement in the source of template-based protein docking.

关键词： Residue-Residue Contacts Domain-Domain Interactions Protein-Protein Interactions Domain Interfaces Residue Co-Evolution Contact Potentials