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Brunner’s gland hyperplasia associated with lipomatous pseudohypertrophy of the pancreas presenting with gastrointestinal bleeding:A case report

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World Journal of Clinical Cases 2021年第31期9卷 9670-9679页

作者： long Cong nguyen Khanh Truong Vu Trang Thi Thuy Vo Chau Ha Trinh Tan Dang Do Ngoc Thi Van Pham Tuyen Van Pham thanh Tuan nguyen Hiep Canh nguyen Jeong-Sik Byeon Gastroenterology and Hepatology Center Bach Mai HospitalHanoi 10000Viet Nam Department of Gastroenterology School of Medicine and PharmacyVietnam National University HanoiHanoi 10000Viet Nam Radiology Center Bach Mai HospitalHanoi 10000Viet Nam Pathology Center Bach Mai HospitalHanoi 10000Viet Nam Department of Human Pathology Kanazawa University Graduate School of MedicineKanazawa 920-8640Japan Department of Gastroenterology Asan Medical CenterUniversity of Ulsan College of MedicineSeoul 05505South Korea

BACKGROUND Brunner’s gland hyperplasia(BGH)is a rare benign lesion of the *** pseudohypertrophy(LiPH)of the pancreas is an extremely rare *** each condition is rare,the probability of purely coincidental coexistence of both conditions is extremely *** SUMMARY We report a 26-year-old man presenting to our hospital with symptoms of recurrent upper gastrointestinal *** gastrointestinal endoscopy showed a huge pedunculated polypoid lesion in the duodenum with bleeding at the base of the *** examination of the duodenal biopsy specimens showed ***,abdominal computed tomography and magnetic resonance imaging revealed marked fat replacement over the entire pancreas,confirmed by histopathological evaluation on percutaneous pancreatic *** on the radiological and histological findings,LiPH of the pancreas and BGH were *** patient refused any surgical ***,he was managed with supportive *** patient’s symptoms improved and there was no further *** This is the first well-documented case showing the coexistence of LiPH of the pancreas and BGH.

关键词： Lipomatous pseudohypertrophy Pancreas Gastrointestinal bleeding Brunner’s gland Case report

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Anticancer effects of saponin and saponin–phospholipid complex of Panax notoginseng grown in Vietnam

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Asian Pacific Journal of Tropical Biomedicine 2016年第9期6卷 795-800页

作者： Thu Dang Kim Hai nguyen thanh Duong nguyen Thuy Loi Vu Duc Thu Vu Thi Hung Vu Manh Patcharee Boonsiri Tung Bui thanh Department of Pharmacology and Clinical Pharmacy School of Medicine and PharmacyVietnam National University Department of Pharmaceutics and Pharmaceutical Technology School of Medicine and PharmacyVietnam National University Department of Pharmacology Hanoi University of Pharmacy Department of Pharmacognosy and Traditional Pharmacy School of Medicine and PharmacyVietnam National University Faculty of Biology VNU University of Science Key Laboratory of Enzyme and Protein Technology VNU University of Science Department of Pharmacology School of PharmacyLac Hong University Department of Biochemistry Faculty of MedicineKhon Kaen University

Objective:To evaluate the antitumor activity both in vitro and in vivo of saponin–phospholipid complex of Panax ***:The in vitro cytotoxic effect of saponins extract and saponin–phospholipid complex against human lung cancer NCI-H460 and breast cancer cell lines BT474 was examined using MTS *** in vivo evaluation of antitumor potential,saponin and saponin–phospholipid complex were administered orally in rats induced mammary carcinogenesis by 7,12-dimethylbenz(a)anthracene,for 30 ***:Our data showed that saponin–phospholipid complex had stronger anticancer effect compared to saponin *** IC50 values of saponin–phospholipid complex and saponin extract for NCI-H460 cell lines were 28.47 mg/m L and 47.97 mg/mL,respectively and these values for BT474 cells were 53.18 mg/mL and 86.24 mg/mL,*** vivo experiments,administration of saponin,saponin–phospholipid complex and paclitaxel(positive control) effectively suppressed 7,12-dimethylbenz(a) anthracene-induced breast cancer evidenced by a decrease in tumor volume,the reduction of lipid peroxidation level and increase in the body weight,and elevated the enzymatic antioxidant activities of superoxide dismutase,catalase,glutathione peroxidase in rat breast ***:Our study suggests that saponin extract from Panax notoginseng and saponin–phospholipid complex have potential to prevent cancer,especially breast cancer.

关键词： Panax notoginseng Saponin Saponin–phospholipid complex Breast cancer Antitumor

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Anti-inflammatory effects of alkaloid enriched extract from roots of Eurycoma longifolia Jack

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Asian Pacific Journal of Tropical Biomedicine 2019年第1期9卷 18-23页

作者： Dao Thi thanh Hien Tran Phi long Tran Phuong Thao Jeong-Hyung Lee Duong Thu Trang nguyen Thi Thu Minh Pham Van Cuong Do Thi Ngoc Lan nguyen Hai Dang nguyen Tien Dat Deparment of Traditional Pharmacy Hanoi University of Pharmacy Department of Biochemistry College of Natural Sciences Kangwon National University Advanced Center for Bio-organic Chemistry Institute of Marine Biochemistry Vietnam Academy of Science and Technology National Institute of Drug Quality Control Center for Research and Technology Transfers

Objective: To examine the in vitro and in vivo anti-inflammatory effects of the alkaloid enriched extract(ELA) from the roots of Eurycoma longifolia. Methods: The in vitro antiinflammatory effects of ELA were evaluated by examining its inhibitory activities against nitric oxide(NO) production and inducible nitric oxide synthase(iN OS) and cyclooxygenase2(COX-2) expressions in lipopolysaccharide(LPS)-stimulated RAW264.7 cells. The level of NO produced in the culture media was determined by Griess method. The i NOS and COX-2 protein expressions were analyzed by Western blot. The in vivo effect of ELA was evaluated on LPS-induced septic shock in mice model. Mice mortality was monitored for5 days after injection of LPS. The chemical contents of the ELA were determined by using various chromatographic and spectroscopic techniques. Results: The ELA was found to exhibit a significant anti-inflammatory effect in both in vitro and in vivo models. The results demonstrated that ELA dose-dependently inhibited LPS-induced NO production as well as the protein iN OS and COX-2 expressions. In the septic shock model, ELA dose-dependently protected mice from LPS-induced mortality. Further study on the isolated components of ELA indicated that 9,10-dimethoxycanthin-6-one may contribute significantly to the antiinflammatory effects of the extract. Conclusions: These results suggest that ELA exhibits the anti-inflammatory activity via suppression of pro-inflammatory mediators such as NO, iN OS,and COX-2 and protects mice from LPS-induced mortality in septic shock model.

关键词： Eurycoma longifolia Anti-inflammation Alkaloid 9,10-dimethoxycanthin-6-one

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Synthesis, characterization and photoactivity of bi-crystalline mesoporous TiO2

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Frontiers of Materials Science 2016年第1期10卷 23-30页

作者： Dongthanh nguyen Wei WANG Haibo long Hongqiang RU Key Laboratory for Anisotropy and Texture of Materials of Ministry of Education (ATM) Northeastern University Shenyang 110819 China School of Materials and Metallurgy Northeastern University Shenyang 110819 China

Mesoporous titania （meso-TiO2） has received extensive attention owing to its versatile potential applications. This paper reports a low-temperature templating approach for the fabrication of meso-TiO2 using the peroxo titanic acid （PTA） sol as precursor and Pluronic P123 as nonionic template. The TGA, XRD, N2 sorption, FE-SEM and HRTEM were used to characterize the obtained samples. The results showed that meso-TiO2 with high surface area up to 163 m2.g^-1 and large pore volume of 0.65 cm3.^-1 can be obtained. The mesopore sizes can be varied between 13 and 20 nm via this synthesis approach. The amount of P123 and the calcination conditions were found to have great influence on the mesoporous and crystalline structures of meso-TiO2. The photocatalytic activity testing clearly shows that the high surface area and bi-crystallinity phases of meso-TiO2 play important roles in enhancing photocatalytic properties of meso-TiO2 in photo-decomposing Rhodamine B in water.

关键词： surfactant templating mesopore bi-crystallinity titania

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Facile and controllable preparation of mesoporous TiO2 using poly（ethylene glycol） as structure-directing agent and peroxotitanic acid as precursor

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Frontiers of Materials Science 2016年第4期10卷 405-412页

作者： Dongthanh nguyen Wei WANG Haibo long Hongqiang RU Key Laboratory for Anisotropy and Texture of Materials (Ministry of Education) School of Materials Science and Engineering Northeastern University Shenyang 110819 China

This work demonstrated that mesoporous TiO= （meso-TiO2） with con- trollable mesoporous and crystalline structures can be facilely prepared by using poly （ethylene glycol）（PEG） as structure-directing （SD） agent and peroxotitanic acid （PTA） as precursor. Meso-TiO2 with high specific surface area （157 m2.g-1）, pore volume （0.45 cm3.g-1） and large mesopore size of 13.9 nm can be obtained after calcination at 450℃. Such meso-TiO2 also shows relatively high thermal stability. BET surface area still reaches 114 m2-g-1 after calcination at 550℃. In the synthesis and calcination process, PEG that plays multiple and important roles in delivering thermally stable and tunable mesoporous and crystalline structures shows to be a suitable low-cost SD agent for the controllable preparation of nanocrystalline meso-TiO2. The photocataiytic activity tests show that both high surface area and bi-crystallinity of obtained meso-TiO2 are important in enhancing the performance in photo-decomposing Rhodamine B in water.

关键词： sol-gel preparation mesoporous titania poly(ethylene glycol)

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Invariant Lighting Hand Posture Classification

Invariant Lighting Hand Posture Classification

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The 2010 IEEE International Conference on Progress in Informatics and Computing

作者： Thi-thanh-Hai Tran Thi-thanh-Mai nguyen MICA International Research Center Hanoi University of Science and Technology VietNam

ISBN: (纸本)9781424467860

＜正＞Hand posture classification is a key problem for many human computer interaction ***,this is not a simple *** this paper,we propose to decompose the hand posture classification problem into 2 *** the first step,we detect skin regions using a very fast algorithm of color segmentation based on thresholding *** segmentation is robust to lighting condition thank to a step of color normalization using neural *** the second step, each skin region will be classified into one of hand posture class using Cascaded Adaboost *** contributions of this paper are:（i） By applying a step of color normalization,the posture classification rate is significantly improved under varying lighting condition;（ii） The cascaded Adaboost technique has been studied for the problem of face detection（2 classes）.In this paper, it will be studied and evaluated in more detail in a problem of classification of hand postures（multi-classes）.

关键词： Hand posture classification Cascaced Adaboost Color normalization Neural network Lighting invariance

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A Model for Selecting a Biomass Furnace Supplier Based on Qualitative and Quantitative Factors

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Computers, Materials & Continua 2021年第11期69卷 2339-2353页

作者： Chia-Nan Wang Hsin-Pin Fu Hsien-Pin Hsu Van thanh nguyen Viet Tinh nguyen Ansari Saleh Ahmar Department of Industrial Engineering and Management National Kaohsiung University of Science and TechnologyKaohsiung80778Taiwan Department of Marketing and Distribution Management National Kaohsiung University of Science and TechnologyKaohsiung80778Taiwan Department of Supply Chain Management National Kaohsiung University of Science and TechnologyKaohsiung80778Taiwan Faculty of Commerce Van Lang UniversityHo Chi Minh City70000Vietnam Faculty Department of Statistics Faculty of Mathematics and Natural SciencesUniversitas Negeri MakassarMakassar90223Indonesia

In developing countries,solar energy is the largest source of energy,accounting for 35%–45%of the total energy *** energy resource plays a vital role in meeting the energy needs of the world,especially in *** has favorable natural conditions for this energy *** it is hot and humid,and it has much rainfall and fertile soil,biomass develops very ***,byproducts from agriculture and forestry are abundant and continuously ***,byproducts that are considered natural waste have become the cause of environmental pollution;these include burning forests,straw,and sawdust in the North;and rice husks dumped into rivers and canals in the Mekong Delta *** energy is provided in a short cycle,is environmentally safe to use and is encouraged by organizations that support sustainable *** advantage of this energy source provides energy for economic development and ensures environmental *** to the abovementioned favorable conditions,many biomass energy plants are being built in *** other renewable energy investment projects,the selection of the construction contractor,the selection of equipment for the installation of the power plant,and the choice of construction site are complex multi-criteria *** this case,decisionmakers must evaluate many qualitative and quantitative *** factors interact with each other and it is difficult to use personal experience to choose the optimal solution for such complex decision-making problems,especially in a fuzzy decision-making ***,in this study,the authors use a Multi-Criteria Decision-Making(MCDM)model that uses a Fuzzy Analytic Hierarchy Process(FAHP)model and the Combined Compromise Solution(CoCoSo)algorithm to select biomass furnace suppliers utilizing both qualitative and quantitative ***,the results of this work will provide the first look at a hybrid CoCoSo/FAHP method that decision-m

关键词： Biomass energy supplier selection biomass furnace MCDM optimization CoCoSo algorithm fuzzy theory FAHP model industry 4.0

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Research on The Development Trend and Countermeasures of Vietnam-China Trade Deficit

Research on The Development Trend and Countermeasures of Vie...

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作者： nguyen THI thanh THU 合肥工业大学

学位级别：硕士

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Xanthine oxidase inhibitors from Archidendron clypearia(Jack.) I.C. Nielsen: Results from systematic screening of Vietnamese medicinal plants

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Asian Pacific Journal of Tropical Medicine 2017年第6期10卷 619-626页

作者： nguyen Thuy Duong Pham Duc Vinh Phuong Thien Thuong nguyen Thi Hoai Le nguyen thanh Tran The Bach nguyen Hai Nam nguyen Hoang Anh Department of Pharmacology Hanoi University of Pharmacy Department of Pharmaceutical Analysis and Standardization National Institute of Medicinal Materials Department of Pharmacognosy Hue University of Medicine and Pharmacy Institute of Marine Biochemistry Vietnam Academy of Science and Technology Institute of Ecology and Biological Resources Vietnam Academy of Science and Technology Department of Medicinal Chemistry Hanoi University of Pharmacy

Objective: To screen Vietnamese medicinal plants for xanthine oxidase(XO) inhibitory activity and to isolate XO inhibitor(s) from the most active plant. Methods: The plants materials were extracted by methanol. The active plant materials were fractionated using different organic solvents, including n-hexane, ethyl acetate, and n-butanol. Bioassay-guided fractionation and column chromatography were used to isolate compounds. The compounds structures were elucidated by analysis of spectroscopic data, including IR, MS, and NMR. Results: Three hundreds and eleven methanol extracts(CME) belonging to 301 Vietnamese herbs were screened for XO inhibitory activity. Among these plants, 57 extracts displayed XO inhibitory activity at 100 μg/m L with inhibition rates of over 50%. The extracts of Archidendron clypearia, Smilax poilanei, Linociera ramiflora and Passiflora foetida exhibited the greatest potency with IC_(50) values below 30 μg/m L. Chemical study performed on the extract of Archidendron clypearia resulted in the isolation of six compounds, including 1-octacosanol, docosenoic acid, daucosterol, methyl gallate, quercitrin and(-)-7-O-galloyltricetiflavan. The compound(-)-7-O-galloyltricetiflavan showed the most potent XO inhibitory activity with an IC_(50) value of 25.5 μmol/L. Conclusions: From this investigation, four Vietnamese medicinal plants were identified to have XO inhibitory effects with IC_(50) values of the methanol extracts below 30 μg/m L. Compound(-)-7-O-galloyltricetiflavan was identified as an XO inhibitor from Archidendron clypearia with IC_(50) value of 25.5 μmol/L.

关键词： Xanthine oxidase Inhibitor Medicinal plants Vietnam

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Numerical investigation of the effect of seasonal variations of depthof-closure on shoreline evolution

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International Journal of Sediment Research 2021年第1期36卷 1-16页

作者： Xuan Tinh nguyen Minh thanh Tran Hitoshi Tanaka Trung Viet nguyen Yuta Mitobe Cong Dien Duong Department of Civil Engineering Tohoku University

The current study presents the effects of seasonal variations in the depth-of-closure（D;） on shoreline evolution using a numerical,one-line shoreline *** erosion of the southern beach of the Nha Trang Coast,which is located in south central of Vietnam,is selected as the study *** study area is immensely influenced by the tropical monsoon climate that has a clear pattern of large waves in the northeast monsoon season and calm waves in the non-monsoon *** analysis of the long-term measured shoreline variations from a video-camera system has found a strong correlation of these variations to the monsoon-dominated wave characteristics in the Nha Trang ***,a new approach for determining the depth-of-closure with consideration of the seasonal wave climate changes is purposed in the current *** implementing this new approach into a numerical,one-line shoreline model,it is found that the seasonal variations of D;appear to better describe the periodical shoreline evolution due to the monsoon-dominated wave characteristics for the Nha Trang *** important findings are considered to commonly apply for monsoon-dominated coastal regions in *** findings are useful information not only for scientific readers but also for the coastal authorities and managers in order to make better countermeasure plans against this kind of erosion mechanism in the future.

关键词： Video camera Shoreline change One-line theory Nha Trang Beach Depth-of-closure Monsoon wave climate

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