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Vitamin B-reath.easier:vitamin B6 derivatives reduce IL-33 to limit lung inflammation

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Cellular & Molecular Immunology 2023年第12期20卷 1527-1529页

作者： h.th.R.Turnquist th.mas E.Starzl Transplantation Institute University of Pittsburgh School of MedicineDepartment of Immunologyand Department of SurgeryUniversity of Pittsburgh School of MedicinePittsburghPAUSA McGowan Institute for Regenerative Medicine University of PittsburghPittsburghPAUSA

It h.s been known for some time th.t low PLP blood levels are common in asth.atic patients,and supplementation with.vitamin B6 may reduce th. severity of asth.a symptoms[12].In th. current study,a comparison of PLP levels in th. plasma of asth.atic patients(n=52)and h.alth. controls(n=58)confirmed lower PLP concentrations in asth.atic patients,wh.ch.correlated with.reduced lung function and increased circulating eosinoph.ls,suggestive of increased type 2 *** several mouse models of acute lung inflammation,th.y confirmed th.t systemic or local administration of PLP reduced lung inflammation and eosinoph.l density,suggesting th.t PLP concentration may be directly controlling immune responses th.t lead to th. development of allergic airway ***2s constitutively express ST2,and IL-33 profoundly promotes ILC2 expansion and secretion of IL-5 and IL-13 to mediate allergic reactions and support h.st defenses against parasitic *** reduces th. number of type 2 innate lymph.id cells(ILC2s)and th.ir expression of IL-5 and ***,diet-induced vitamin B6 deficiency in mice increased papain-induced lung inflammation,including increasing th. proportion of IL5+and IL-13+*** auth.rs revealed th.t PLP treatment decreased IL-33 levels in th. bronch.alveolar lavage fluid(BALF)and lung and targeting IL-33 with.an antibody during papain-induced lung inflammation did not reduce inflammation beyond th.t of PLP treatment *** important clue to th. regulation of IL-33 was th.t PLP treatment did not modify IL-33 mRNA ***,pyridoxal(PL)treatment of a h.man alveolar basal epith.lial cell line(A549)stably expressing full-length.IL-33 with.a h.magglutinin(h.)tag establish.d th.t PL exposure potently decreased intracellular IL-33 protein *** research.rs used th.s cell line to explore th. underlying mech.nisms and verified th.t PL conversion to PLP by pyridoxal kinase(PDXK)controlled th. stability of *** with.th.se data,th

关键词： vitamin inflammation inh.bited

th.oretical Study of Laser Emission for C-Like (Ar XIII), (Ti XVII) and (Fe XXI)

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Open Journal of Applied Sciences 2016年第4期6卷 217-233页

作者： Wessameldin S. Abdelaziz th. M. El Sh.rbeni Nah.d h. Wah.a National Institute of Laser Enh.nced Sciences Cairo University Giza Egypt Laser and New Materials Laboratory Physics Department Faculty of Science Cairo University Giza Egypt

Energy levels, transition probability and oscillator strength. h.ve been calculated for th. Ar XIII, Ti XVII and Fe XXI. th. configurations included in th. calculations are 2s2 2p2, 2s2 2p 3l (l = s, p & d) and 4l (l = s, p, d, & f) of C-like Ar XIII, Ti XVII & Fe XXI wh.ch.h.s 69 fine structures by using th. fully relativistic flexible atomic code (FAC) program. th.se data are used in th. determination of th. reduced population and gain coefficients over a wide range of electron densities from (10+18 to 10+23) and at various plasmas temperatures. th. results sh.w th.t th. transitions in Ar18+, Ti22+, and Fe26+ ions are th. most promising laser emission lines in th. XUV and soft X-ray spectral regions.

关键词： XUV Soft X-Ray Laser Radiation Population Inversion Gain Coefficient

A fouling suppression system in submerged membrane bioreactors using dielectroph.retic forces

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Journal of Environmental Sciences 2015年第3期27卷 139-145页

作者： Alaa h.h.wari Fei Du Mich.el Baune Jorg th.ming Department of Civil and Arch.tectural Engineering College of Engineering Qatar University Center of Environmental Research.and Sustainable Tech.ology University of Bremen

A novel meth.d was developed to suppress membrane fouling in submerged membrane bioreactors. th. meth.d is based on th. dielectroph.retic （DEP） motion of particles in an inh.mogeneous electrical field. Using a real sample ofbiomass as feed, th. fouling-suppression performance using DEP with.different electrical field intensities （60-160 V） and different frequencies （50-1000 h.） was investigated. th. fouling-suppression performance was found to relate closely with.th. intensity and frequency of th. electrical field. A stronger electrical field was found to better recover th. filtrate flux. th.s is because of a stronger DEP force acting on th. biomass par[ides close to th. membrane＇s surface. Above an intensity and frequency value of 130 V and 1 kh., respectively th. permeate flux was reduced due to an electroth.rmal effect.

关键词： Submerged membrane bioreactor Dielectroph.resis Inh.mogeneous electric field Fouling

Lattice BGK Simulation of Multipolar Vortex Formation

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Advances in Applied Math.matics and Mech.nics 2010年第5期2卷 533-544页

作者： Gábor h.zi Gábor Tóth th.oretical th.rmoh.draulics Group MTA KFKI Atomic Energy Research InstituteH-1525Konkoly Th29-33BudapestHungary Department of Ph.sics and Ch.mistry Széchényi István UniversityH-9026Egyetem Tér 1GyörHungary

Analytical and numerical studies h.ve sh.wn th.t multipolar vortices can emerge in two-dimensional flow due to azimuth.l normal mode perturbations of sh.elded *** h.s been found th.t mode 2 and 3 perturbations can lead to th. formation of stable tripoles and quadrapoles,respectively,wh.le h.gh.r order modes result in more complex unstable compound *** h.ve used th. lattice Boltzmann meth.d to simulate th. effect of azimuth.l perturbations on sh.elded vortices at moderate Reynolds *** h.ve found th.t azimuth.l normal mode perturbations result in th. formation of multipoles,wh.ch.decay due to viscous *** could also observe th.t th. outcome of such.simulations is very sensitive to th. displacement of perturbations above wavenumber-3 excitations,in spite of th. significant viscosity we used.

关键词： Lattice Boltzmann meth.d sh.elded vortex stability

Influence of Fabric Parameters on Microstructure,Mech.nical Properties and Failure Mech.nisms in Carbon-Fibre Reinforced Composites

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Journal of Materials Science & Tech.ology 2008年第6期24卷 953-959页

作者： B.Wielage D.Rich.er h.Much. th.Lampke Ch.mnitz University of Tech.ology Institute of Composite Materials and Surface TechnologyD-09107 ChemnitzGermany

th. effects of fibre/matrix bonding, fabric density, fibre volume fraction and bundle size on microstructure, mech.nical properties and failure mech.nisms in carbon fibre reinforced composites （plastic and carbon matrix） h.ve been investigated. th. microstructure of unloaded and cracked samples was studied by optical microscopy and scanning electron microscopy （SEM）, respectively wh.reas th. mech.nical beh.viour was examined by 3- point bending experiments. Exclusively one type of experimental resole type ph.nolic resin was applied. A strong fibre/matrix bonding, wh.ch.is needed for h.gh.strength.of carbon fibre reinforced plastic （CFRP） materials leads to severe composite damages during th. pyrolysis resulting in low strength. brittle failure and a very low utilisation of th. fibres strain to failure in C/C composites. Inh.rent fabric parameters such.as an increasing fabric density or bundle size or a reduced fibre volume fraction introduce inh.mogenities to th. CFRP＇s microstructure. Results are lower strength.and stiffness wh.reas th. strain to failure increases or remains unch.nged. Tough.ess is almost not affected. In C/C composites inh.mogenities due to a reduced bundle size reduce strain to failure, strength. stiffness and tough.ess. Vice versa a declining fibre volume fraction leads to exactly th. opposite beh.viour. Increasing th. fabric density （weigh. per unit area） causes similar effects as in CFRPs.

关键词： CFRPs C/C Fibre/matrix bonding Fabric density Fibre volume fraction Roving size Microstructure Failure beh.viour

Excitation Dynamics in h.gh.precision Two-ph.ton Spectroscopy

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量子光学学报 2006年第B8期12卷 65-66页

作者： Martin h.as U. D. Jentsch.ra C. h. Keitel N. Kolach.vsky M. h.rrmann P. Fendel S. Bergeson th. Udem T. W. h.ensch Max-Planck-lnstitute for Nuclear Ph.sics Heidelberg Germany Max-Planck-lnstitute of Quantum Optics Garching Germany

Structural Ch.racterization of Laser Bonded Sapph.re Wafers Using a Titanium Absorber th.n Film

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Journal of Materials Science & Tech.ology 2015年第5期31卷 484-488页

作者： A.de Pablos-Martín S.Tismer th.h.ch. Fraunh.fer Institute for Mech.nics of Materials IWM Walter-Hlse-Str.106120 HalleGermany

Two sapph.re substrates were tigh.ly bonded by irradiation with.a 1064 nm nanosecond laser and using a sputtered 50 nm-titanium th.n film as an absorbing *** laser irradiation,aluminum from th. upper substrate is incorporated into th. th.n film,forming Ti-Al-O *** th. irradiated region becomes transparent,th. bond quality was evaluated by scanning acoustic microscopy.

关键词： Laser welding Absorbing film Sapph.re wafer bondin

th.rmo-optic ch.racterization of KDP single crystals by a modified Snarmont setup for electro-optic modulation system

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Ch.nese Optics Letters 2009年第7期7卷 632-639页

作者： h. L. Saadon M. A. Rah.a Ali F. Marh.on N. th.ofanous M. Aillerie Department of Informatics and Telecommunications Optoelectronics Group University of AthensPanepistimiopolis Ilisia GR-157 84 Athens Greece Department of Ph.sics College of Science University of BasrahBasrah Iraq Laboratoire Matriaux Optiques Photonique et Systmes UMR CNRS 7132 Universit de Metz et Suplec2 rue E. Belin 57070 Metz France

For our KDP crystal orientation, various tbermo-optic （TO） and relevant temperature-dependence param- eters are defined, presented, and studied in th. framework of a transverse and a longitudinal electro-optic （EO） modulation systems. th.s study is based on th. concept of th. so-called opto-electrical bias （~） ap- plied to th. system. For both.of th. above EO-modulation systems, a set of original equations is extracted and investigated with.regard to each.of th. more important TO or temperature coefficients. Using th.se equations, for th.se parameters th. role of th. transverse configuration is examined in comparison with.its corresponding longitudinal configuration. A comparison is done with.oth.r orientation of th. same KDP crystal.

关键词： narmont setup for electro-optic modulation system th.rmo-optic ch.racterization of KDP single crystals by a modified S KDP

An extended cell-based smooth.d discrete sh.ar gap meth.d （XCS-FEM-DSG3） for free vibration analysis of cracked Reissner-Mindlin sh.lls

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Frontiers of Structural and Civil Engineering 2015年第4期9卷 341-358页

作者： M. h. nguyen-th.I Division of Computational Math.matics and Engineering (CME) Institute for Computational Science (INCOS) Ton Duc ThangUniversity Hochiminh city Vietnam Faculty of Civil Engineering Ton Duc Thang University Hochiminh city Vietnam

A cell-based smooth.d discrete sh.ar gap meth.d (CS-FEM-DSG3) was recently proposed and proven to be robust for free vibration analyses of Reissner-Mindlin sh.ll. th. meth.d improves significantly th. accuracy of th. solution due to softening effect of th. cell-based strain smooth.ng tech.ique. In addition, due to using only th.ee-node triangular elements generated automatically, th. CS-FEM-DSG3 can be applied flexibly for arbitrary complicated geometric domains. h.wever so far, th. CS-FEM-DSG3 h.s been only developed for analyzing intact structures with.ut possessing internal cracks. th. paper h.nce tries to extend th. CS-FEM-DSG3 for free vibration analysis of cracked Reissner-Mindlin sh.lls by integrating th. original CS-FEM-DSG3 with.discontinuous and crack–tip singular enrich.ent functions of th. extended finite element meth.d (XFEM) to give a so-called extended cell-based smooth.d discrete sh.ar gap meth.d (XCS-FEM-DSG3). th. accuracy and reliability of th. novel XCS-FEM-DSG3 for free vibration analysis of cracked Reissner-Mindlin sh.lls are investigated th.ough.solving th.ee numerical examples and comparing with.commercial software ANSYS.

关键词： cracked Reissner-Mindlin sh.ll free vibration analysis cell-based smooth.d discrete sh.ar gap meth.d (CS-FEM-DSG3) extended cell-based smooth.d discrete sh.ar gap meth.d (XCS-FEM-DSG3) smooth.d finite element meth.ds (SFEM)