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Predicting 3D Radiotherapy Dose-Volume Based on Deep Learning

Intelligent Automation & Soft Computing 2024年第2期39卷 319-335页

作者： Do Nang Toan Lam Thanh Hien Ha Manh Toan nguyen Trong Vinh Pham Trung hieu Institute of Information Technology Vietnam Academy of Science and TechnologyHanoi10072Vietnam Faculty of Information Technology Lac Hong UniversityBien HoaDong Nai76120Vietnam

Cancer is one of the most dangerous diseaseswith *** of the principal treatments is radiotherapy by using radiation beams to destroy cancer cells and this workflow requires a lot of experience and skill from doctors and *** our study,we focused on the 3D dose prediction problem in radiotherapy by applying the deeplearning approach to computed tomography(CT)images of cancer *** image data has more complex characteristics than normal image data,and this research aims to explore the effectiveness of data preprocessing and augmentation in the context of the 3D dose prediction *** proposed four strategies to clarify our hypothesis in different aspects of applying data preprocessing and *** strategies,we trained our custom convolutional neural network model which has a structure inspired by the U-net,and residual blocks were also applied to the *** output of the network is added with a rectified linear unit(Re-Lu)function for each pixel to ensure there are no negative values,which are absurd with radiation *** experiments were conducted on the dataset of the Open Knowledge-Based Planning Challenge which was collected from head and neck cancer patients treatedwith radiation *** results of four strategies showthat our hypothesis is rational by evaluating metrics in terms of the Dose-score and the Dose-volume histogram score(DVH-score).In the best training cases,the Dose-score is 3.08 and the DVH-score is *** addition,we also conducted a comparison with the results of another study in the same context of using the loss function.

关键词： CT image 3D dose prediction data preprocessing augmentation

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GLOBAL BOUND ON THE GRADIENT OF SOLUTIONS TO p-LAPLACE TYPE EQUATIONS WITH MIXED DATA

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Acta Mathematica Scientia 2024年第4期44卷 1394-1414页

作者： Minh-Phuong TRAN The-Quang TRAN Thanh-Nhan nguyen Applied Analysis Research Group Faculty of Mathematics and StatisticsTon Duc Thang UniversityHo Chi Minh CityVietnam nguyen huu Huan High School Thu Duc CityVietnam Group of Analysis and Applied Mathematics Department of MathematicsHo Chi Minh City University of EducationVietnam

In this paper,the study of gradient regularity for solutions of a class of elliptic problems of p-Laplace type is *** particular,we prove a global result concerning Lorentz-Morrey regularity of the non-homogeneous boundary data problem:-div((s^(2)+|▽u|^(2)p-2/2)▽u)=-div(|f|^(p-2)f)+g inΩ,u=h in■Ω,with the(sub-elliptic)degeneracy condition s∈[0,1]and with mixed data f∈L^(p)(Q;R^(n)),g∈Lp/(p-1)(Ω;R^(n))for p∈(1,n).This problem naturally arises in various applications such as dynamics of non-Newtonian fluid theory,electro-rheology,radiation of heat,plastic moulding and many *** on the idea of level-set inequality on fractional maximal distribution functions,it enables us to carry out a global regularity result of the solution via fractional maximal *** to the significance of M_(α)and its relation with Riesz potential,estimates via fractional maximal functions allow us to bound oscillations not only for solution but also its fractional derivatives of orderα.Our approach therefore has its own interest.

关键词： gradient estimates p-Laplace quasilinear elliptic equation fractional maximal operators Lorentz-Morrey spaces

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Is convenience really king? Comparative evaluation of catastrophic costs due to tuberculosis in the public and private healthcare sectors of Viet Nam: a longitudinal patient cost study

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贫困所致传染病(英文) 2024年第2期13卷 1-12页

作者： nguyen Hoa Binh Quang Vo Luan nguyen Forse Rachel Jeanette Wiemers Anja Maria Christine Huynh Huy Ba Dong Thuy Thi Thu Phan Yen Thi Hoang Creswell Jacob Dang Thi Minh Ha nguyen Lan huu Shedrawy Jad L?nnroth Knut nguyen Tuan Dinh Van Dinh Luong Annerstedt Kristi Sidney Codlin Andrew James National Lung Hospital Ha Noi Viet Nam Friends for International TB Relief Ha Noi Viet Nam Department of Global Public Health WHO Collaboration Centre On Tuberculosis and Social Medicine Karolinska Institute Stockholm Sweden Stop TB Partnership Geneva Switzerland Pham Ngoc Thach Hospital Ho Chi Minh City Viet Nam

Background In Viet Nam, tuberculosis (TB) represents a devastating life-event with an exorbitant price tag, partly due to lost income from daily directly observed therapy in public sector care. Thus, persons with TB may seek care in the private sector for its flexibility, convenience, and privacy. Our study aimed to measure income changes, costs and catastrophic cost incurrence among TB-affected households in the public and private *** Between October 2020 and March 2022, we conducted 110 longitudinal patient cost interviews, among 50 patients privately treated for TB and 60 TB patients treated by the National TB Program (NTP) in Ha Noi, Hai Phong and Ho Chi Minh City, Viet Nam. Using a local adaptation of the WHO TB patient cost survey tool, participants were interviewed during the intensive phase, continuation phase and post-treatment. We compared income levels, direct and indirect treatment costs, catastrophic costs using Wilcoxon rank-sum and chi-squared tests and associated risk factors between the two cohorts using multivariate *** The pre-treatment median monthly household income was significantly higher in the private sector versus NTP cohort (USD 868 vs USD 578;P=0.010). However, private sector treatment was also significantly costlier (USD 2075 vs USD 1313;P=0.005), driven by direct medical costs which were 4.6 times higher than costs reported by NTP participants (USD 754 vs USD 164;P<0.001). This resulted in no significant difference in catastrophic costs between the two cohorts (Private: 55% vs NTP: 52%;P=0.675). Factors associated with catastrophic cost included being a single-person household [adjusted odds ratio [(aOR=13.71; 95% confidence interval (CI): 1.36–138.14;P=0.026], unemployment during treatment (aOR=10.86; 95%CI: 2.64–44.60;P<0.001) and experiencing TB-related stigma (aOR=37.90; 95%CI: 1.72–831.73;P=0.021).Conclusions Persons with TB in Viet Nam face similarly high risk of catastrophic costs whether treated in the

关键词： Tuberculosis Patient cost Catastrophic cost Private sector Comparative analysis Viet Nam

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A Study on Optimizing the Double-Spine Type Flow Path Design for the Overhead Transportation System Using Tabu Search Algorithm

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Intelligent Automation & Soft Computing 2024年第2期39卷 255-279页

作者： nguyen huu Loc Khuu Thuy Duy Truong Quoc Dien Le Tran Thanh Cong Vu Hoa Binh Tran Tuong Quan Vo Department of Mechatronics Faculty of Mechanical EngineeringHo Chi Minh City University of Technology(HCMUT)Ho Chi Minh CityVietnam Bach Khoa Research Center for Manufacturing Engineering Ho Chi Minh City University of Technology(HCMUT)Ho Chi Minh CityVietnam VietnamNational University Ho ChiMinh City Ho ChiMinh CityVietnam

Optimizing Flow Path Design(FPD)is a popular research area in transportation system design,but its application to Overhead Transportation Systems(OTSs)has been *** study focuses on optimizing a double-spine flow path design for OTSs with 10 stations by minimizing the total travel distance for both loaded and empty *** employ transportation methods,specifically the North-West Corner and Stepping-Stone methods,to determine empty vehicle travel ***,the Tabu Search(TS)algorithm is applied to branch the 10 stations into two main layout *** results obtained from our proposed method demonstrate a reduction in the objective function value compared to the initial feasible ***,we explore howchanges in the parameters of the TS algorithm affect the optimal *** validate the feasibility of our approach by comparing it with relevant literature and conducting additional tests on layouts with 20 and 30 stations.

关键词： Overhead transportation systems tabu search double-spine layout transportationmethod empty travel flow path design

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Complexities and pitfalls in analyzing and interpreting mitochondrial DNA content in human cancer

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Journal of Genetics and Genomics 2020年第7期47卷 349-359页

作者： hieu nguyen Thomas LaFramboise Vinmec Research Institute of Stem Cell and Gene Technology(VRSIG) 458 M inh KhaiVinh TuyHai Ba TrungHanoiViet Nam Department of Genetics and Genome Sciences Case Western Reserve University School of Medicine10900 Euclid AvenueClevelandOH44106USA

Mutations in the human mitochondrial genome have been observed in all types of human cancer,indicating that mutations might contribute to tumorigenesis,metastasis,recurrence,or drug *** possibility is appealing because of the known shift from oxidative metabolism to glycolysis,known as the Warburg effect,that occurs in *** DNA(mtDNA)mutations could either bematernally inherited and predispose to cancer(germ line mutations)or occur sporadically in the mtDNA of specific tissues(rissue-or tumor-specific somatic mutations)and contribute to the tumor initiation and progression ***-throughput sequencing technologies now enable comprehensive detection of mtDNA variation in tissues and bodily fluids,with the potential to be used as an early detectiontool that may impact the treatment of ***,we discuss insights into the roles of mtDNA mutations in carcinogenesis,highlighting the complexities involved in the analysis and interpretation of mitochondrial genomic *** challenges in studying their contribution to pathogenesis,and the value of mtDNA mutations in developing early detection,diagnosis,prognosis,and therapeuticstrategics for cancer.

关键词： Mitochondrial DNA Cancer Genetic variation

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Face Mask Recognition for Covid-19 Prevention

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Computers, Materials & Continua 2022年第11期73卷 3251-3262页

作者： Trong hieu Luu Phan nguyen Ky Phuc Zhiqiu Yu Duy Dung Pham huu Trong Cao College of Engineering Can Tho UniversityCan Tho city910900Viet Nam International University-Vietnam National University Vietnam National UniversityHoChiMinh City70000Vietnam Department of Industrial Management National Taiwan University of Science and TechnologyTaipei10607Taiwan

In recent years,the COVID-19 pandemic has negatively impacted all aspects of social *** to ease in the infected method,i.e.,through small liquid particles from the mouth or the nose when people cough,sneeze,speak,sing,or breathe,the virus can quickly spread and create severe problems for people’s *** to some research as well as World Health Organization(WHO)recommendation,one of the most economical and effective methods to prevent the spread of the pandemic is to ask people to wear the face mask in the public space.A face mask will help prevent the droplet and aerosol from person to person to reduce the risk of virus *** simple method can reduce up to 95%of the spread of the ***,this solution depends heavily on social consciousness,which is sometimes *** order to improve the effectiveness of wearing face masks in public spaces,this research proposes an approach for detecting and warning a person who does not wear or misuse the face *** approach uses the deep learning technique that relies on GoogleNet,AlexNet,and VGG16 *** results are synthesized by an ensemble method,i.e.,the bagging *** the experimental results,the approach represents a more than 95%accuracy of face mask recognition.

关键词： Face mask detection deep learning AlexNet GoogLeNet VGG16 ensemble method

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Graphene-driving novel strain relaxation towards AlN film and DUV photoelectronic devices

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Light(Science & Applications) 2022年第7期11卷 1318-1319页

作者： hieu.P.T.nguyen New Jersey Institute of Technology Department of Electrical&Computer EngineeringNewarkNJ 07102USA

Graphene-driving strain-pre-store engineering enables the epitaxy of strain-free AlN film with low dislocation density for DUV-LED and the unique mechanism of strain-relaxation in QvdW epitaxy was demystified.

关键词： driving relaxation strain

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STABILITY ANALYSIS OF A COMPUTER VIRUS PROPAGATION MODEL WITH ANTIDOTE IN VULNERABLE SYSTEM

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Acta Mathematica Scientia 2016年第1期36卷 49-61页

作者： nguyen huu KHANH nguyen Bich HUY Department of Mathematics College of Natural SciencesCan Tho University Departmet of Mathematics Ho Chi Minh University of Education

We study a proposed model describing the propagation of computer virus in the network with antidote in vulnerable system. Mathematical analysis shows that dynamics of the spread of computer viruses is determined by the threshold Ro. If Ro 〈 1, the virusfree equilibrium is globally asymptotically stable, and if R0 〉 1, the endemic equilibrium is globally asymptotically stable. Lyapunov functional method as well as geometric approach are used for proving the global stability of equilibria. A numerical investigation is carried out to confirm the analytical results. Through parameter analysis, some effective strategies for eliminating viruses are suggested.

关键词： computer virus virus-free equilibrium endemic equilibrium global stability antidote

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Epidemiology and Clonal Spread Evidence of Carbapenem-Resistant Organisms in the Center of Care and Protection of Orphaned Children, Vietnam

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Open Journal of Medical Microbiology 2024年第3期14卷 165-189页

作者： Van Kim nguyen Pirom Noisumdaeng Pol. Maj. Katiya Ivanovitch Stephen Baker Eugene Athan Stephanie Jones Le Thi Lan Larry Croft Yin Peng Lee Tara Cassidy Van Hung Tran Thi Hang Phan huu Tinh Ho Faculty of Public Health Thammasat University Bangkok Thailand Department of Prevention and Infection Control Hung Vuong Hospital HCM City Vietnam Microbiology of Faculty of Public Health Thammasat University Bangkok Thailand Thammasat University Research Unit in Modern Microbiology and Public Health Genomics Thammasat University Bangkok Thailand National Heart & Lung Institute (NHLI) University of Cambridge Cambridge UK Barwon South West Public Health Unit Geelong Australia Center for Innovation in Infectious Disease and Immunology Research (CIIDIR) Geelong Australia School of Medicine Deakin University Burwood Australia Monash Health Berwick Australia Center of Care and Protection of Orphaned Children HCM City Vietnam Charles River Laboratories Microbial Solutions Melbourne Australia Personnel Department of Nhan Dan Gia Dinh Hospital HCM City Vietnam Hung Vuong Hospital HCM City Vietnam Department of Epidemiology Institute of Public Health HCM City Vietnam

Objective: To determine the prevalence of colonization and transmission of carbapenem-resistant Gram-negative organisms in order to develop of an effective infection prevention program. Design: Cross-sectional study with carbapenem-resistant organisms (CRO) colonization detection from the fecal specimens of 20 Health Care Workers (HCWs) and 67 residents and 175 random environment specimens from September 2022 to September 2023. Setting: A Care and Protection Centre of Orphaned Children in South of HCM City. Participants: It included 20 HCWs, 67 residents, and 175 randomly collected environmental specimens. Method: Rectal and environmental swabs were collected from 20 HCWs, 67 residents (most of them were children), and 175 environmental specimens. MELAB Chromogenic CARBA agar plates, Card NID, and NMIC-500 CPO of the BD Phoenix TM Automated Microbiology System and whole genome sequencing (WGS) were the tests to screen, confirm CROs, respectively and determine CRO colonization and transmission between HCWs, residents, and the environment. Result: We detected 36 CRO isolates, including 6, 11 and 19 CROs found in 6 HCWs, 10 residents and 19 environments. The prevalence of detectable CRO was 30% (6/20) in HCWs, 14.92% (10/67) in residents, and 10.86% (19/175) in environmental swabs in our study. WGS demonstrated CRO colonization and transmission with the clonal spread of E. coli and A. nosocomialis, among HCWs and residents (children). Conclusion: Significant CRO colonization and transmission was evident in HCWs, residents, and the center environment. Cleaning and disinfection of the environment and performing regular hand hygiene are priorities to reduce the risk of CRO colonization and transmission.

关键词： Carbapenem-Resistant Organisms Contamination Hand Hygiene Whole Genome Sequencing Infection Prevention

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Electronic Band Structure of Carbon Nanotubes with Kekule Structure

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Chinese Physics Letters 2013年第9期30卷 97-100页

作者： nguyen Ngoc hieu Le Cong Nhan Center of Research and Development Duy Tan UniversityK7/25 Quang TrungDa NangViet Nam Department of Environmental Science Saigon University273 An Duong VuongHo Chi Minh cityViet Nam

Electronic band structure of carbon nanotubes with the Kekule structure is studied by the tight-binding *** give a complete geometrical approach to structural properties of carbon nanotubes with bond alternation,including chiral and achiral *** the Kekule is introduced,all carbon nanotubes become semiconducting with a small band gap at the Fermi *** band gap of the carbon nanotubes depends only on the difference between C–C bond lengths or the resonance integrals.

关键词： carbon structure Fermi

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