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Truly optimal semi-active damping to control free vibration of a single degree of freedom system

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Theoretical & Applied Mechanics Letters 2024年第2期14卷 142-145页

作者： Viet duc La Ngoc Tuan nguyen Institute of Mechanics Vietnam Academy of Science and TechnologyHanoi 10000Vietnam Graduate University of Science and Technology Vietnam Academy of Science and TechnologyHanoi 10000Vietnam

This paper studies a single degree of freedom system under free vibration and controlled by a general semiactive damping.A general integral of squared error is considered as the performance index.A one-time switching damping controller is proposed and *** pontryagin maximum principle is used to prove that no other form of semi-active damping can provide the better performance than the proposed one-time switching damping.

关键词： Analytical optimization Quadratic integral Lyapunov equation Pontryagin maximum principle

Autohydrolysis treatment of bamboo and potassium oxalate(K_(2)C_(2)O_(4))activation of bamboo product for CO_(2) capture utilization

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Frontiers of Chemical Science and Engineering 2024年第4期18卷 63-72页

作者： dang duc Viet Doan Thi Thao Khuong Duy Anh Toshiki Tsubota Department of Materials Science Faculty of EngineeringKyushu Institute of TechnologyFukuoka 804-8550Japan Vietnamese Academy of Forest Sciences Hanoi 10000Vietnam Collaborative Research Centre for Green Materials on Environmental Technology Kyushu Institute of TechnologyFukuoka 808-0196Japan

Typically,the hydroxide agents,such as sodium hydroxide and potassium hydroxide,which have corrosive properties,are used in the carbon activation *** this study,potassium oxalate(K_(2)C_(2)O_(4)),a less toxic and non-corrosive activating reagent,was used to synthesize activated carbon from the solid residue after autohydrolysis *** effect of the autohydrolysis treatment and the ratio of the K_(2)C_(2)O_(4)/solid residue are presented in this ***,the comparison between the activated carbon from bamboo and biochar from the solid residue are also *** resulting activated carbon from the solid residue exhibited a high surface area of up to 1432 m^(2)·g^(-1) and a total pore volume of up to 0.88 cm^(3)·g^(-1).The autohydrolysis treatment enhanced the microporosity properties compared to those without pretreatment of the activated *** microporosity of the activated carbon from the solid residue was dominated by the pore width at 0.7 nm,which is excellent for CO_(2) *** 25℃ and 1.013×10^(5) Pa,the CO_(2) captured reached up to 4.1 mmol·g^(-1).On the other hand,the ratio between K_(2)C_(2)O_(4) and the solid residue has not played a critical role in determining the porosity *** ratio of the K_(2)C_(2)O_(4)/solid residue of 2 could help the carbon material reach a highly microporous textural property that produces a high carbon capture *** finding proved the benefit of using the solid residue from the autohydrolysis treatment as a precursor material and offering a more friendly and sustainable activation carbon process.

关键词： activated carbon bamboo biochar CO_(2)capture potassium oxalate

Forecasting measured responses of structures using temporal deep learning and dual attention

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Frontiers of Structural and Civil Engineering 2024年第6期18卷 832-850页

作者： Viet-Hung dang Trong-Phu nguyen Thi-Lien PHAM Huan X.nguyen Department of Structural Mechanics Hanoi University of Civil EngineeringHanoi 11600Vietnam Faculty of Applied Science University of Economics-Technology for IndustriesHanoi 11600Vietnam London Digital Twin Research Centre Faculty of Science and TechnologyMiddlesex UniversityLondon NW44BTUK International School Vietnam National UniversityHanoi 11600Vietnam

The objective of this study is to develop a novel and efficient model for forecasting the nonlinear behavior of structures in response to time-varying random *** key idea is to design a deep learning architecture to leverage the relationships,between external excitations and structure's vibration signals,and between historical values and future values,within multiple time-series *** proposed method consists of two main steps:the first step applies a global attention mechanism to combine multiple-measured time series and time-varying excitation into a weighted time series before feeding it to a temporal architecture;the second step utilizes a self-attention mechanism followed by a fully connected layer to predict multi-step future *** viability of the proposed method is demonstrated via two case studies involving synthetic data from a three-dimensional(3D)reinforced concrete structure and experimental data from an 18-story steel ***,comparison and robustness studies are carried out,showing that the proposed method outperforms conventional methods and maintains high performance in the presence of noise with an amplitude of less than 10%.

关键词： structural dynamic time-varying excitation deep learning signal processing response forecasting

Wedelolactone from Eclipta prostrata(L)*** inflammation and improves insulin resistance

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Asian Pacific Journal of Tropical Biomedicine 2024年第6期14卷 253-258页

作者： Trinh Tat Cuong Duong duc Thien Hoang Hai Yen nguyen Anh duc Trinh Quang Nam Do Viet Khanh Key Laboratory for Enzyme and Protein Technology Vietnam National University University of ScienceHanoiVietnam Faculty of Biology Vietnam National University University of ScienceHanoiVietnam Hanoi University of Pharmacy HanoiVietnam Vinschool HanoiVietnam

Objective:To evaluate the effects of wedelolactone,a major flavonoid from Vietnamese Eclipta prostrata(L)L.,on inflammation and insulin ***:Wedelolactone was extracted from the leaves of Vietnamese Eclipta prostrata(L.)*** methanol by *** effects of wedelolactone on lipopolysaccharide(LPS)-induced cytokine production,reactive oxygen species(ROS)generation,and nicotinamide adenine dinucleotide phosphate(NADPH)oxidase activities in Raw 264.7 cells were measured by enzyme-linked immunosorbent assay(ELISA),specific immunofluorescent dyes and luminometric analysis,*** addition,its effects on glucose uptake and the protein expression of insulin receptor substrate 1(IRS1)and glucose transporter 4(GLUT4)were examined in 3T3-L1 cells by immunofluorescent dyes and Western ***:Wedelolactone at 30μg/mL significantly inhibited LPS-induced production of tumor necrosis factor-α,interleukin(IL)-6,and IL-8(Pduced ROS generation and NADPH oxidase activities in LPS-stimulated Raw 264.7 cells(P<0.01).Furthermore,wedelolactone showed anti-insulin resistance activity,as evidenced by improved glucose uptake and the upregulated expression of IRS1 and GLUT4 in 3T3-L1 cells(P<0.01).Conclusions:Wedelolactone exhibits anti-inflammation and anti-insulin resistance effects,which may be used for the treatment of diabetes and inflammation-associated diseases.

关键词： Wedelolactone Eclipta prostrata Inflammatory responses Anti-insulin resistance Diabetes IRS1 GLUT4

A comparative study on kinetics and dynamics of two dump truck lifting mechanisms using MATLAB simscape

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Theoretical & Applied Mechanics Letters 2024年第2期14卷 146-156页

作者： Thong duc Hong Minh Quang Pham Son Cong Tran Lam Quang Tran Truong Thanh nguyen Faculty of Transportation Engineering Ho Chi Minh City University of Technology(HCMUT)Ho Chi Minh City 700000Vietnam Vietnam National University Ho Chi Minh City(VNU-HCM) Ho Chi Minh City 700000Vietnam Industrial Maintenance Training Center Ho Chi Minh City University of Technology(HCMUT)Ho Chi Minh City 700000Vietnam

In this paper,two lifting mechanism models with opposing placements,which use the same hydraulic hoist model and have the same angle of 50°,have been *** mechanical and hydraulic simulation models are established using MATLAB Simscape to analyze their kinetics and dynamics in the lifting and holding *** simulation findings are compared to the analytical calculation results in the steady state,and both methods show good *** the early lifting stage,Model 1 produces greater force and discharges goods in the container faster than Model ***,Model 2 reaches a higher force and ejects goods from the container cleaner than its counterpart at the end lifting *** established simulation models can consider the effects of dynamic loads due to inertial moments and forces generated during the system *** is crucial in studying,designing,and optimizing the structure of hydraulic-mechanical systems.

关键词： Dump truck Lifting mechanism Hydraulic MATLAB Simscape Kinetic dynamic analysis

Adiponectin restores the obesity-induced impaired immunomodulatory function of mesenchymal stromal cells via glycolytic reprogramming

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Acta Pharmaceutica Sinica B 2024年第1期14卷 273-291页

作者： duc-Vinh Pham Thi-Kem nguyen Bao-Loc nguyen Jong-Oh Kim Jee-Heon Jeong Inho Choi Pil-Hoon Park Department of Pharmacology Hanoi University of PharmacyHanoi 100000Viet Nam College of Pharmacy Yeungnam UniversityGyeongsan 38541Republic of Korea Department of Medical Biotechnology Yeungnam UniversityGyeongsan 38541Republic of Korea Research Institute of Cell Culture Yeungnam UniversityGyeongsan 38541Republic of Korea Department of Precision Medicine School of MedicineSungkyunkwan UniversitySuwon 16419Republic of Korea

Obesity has been known to negatively modulate the life-span and immunosuppressive potential of mesenchymal stromal cells(MSC).However,it remains unclear what drives the compromised potency of obese *** this study,we examined the involvement of adiponectin,an adipose tissuederived hormone,in obesity-induced impaired therapeutic function of ***-induced obesity leads to a decrease in serum adiponectin,accompanied by impairment of survival and immunomodulatory effects of adipose-derived MSC(ADSC).Interestingly,priming with globular adiponectin(gAcrp)improved the immunomodulatory potential of obese *** effects were also observed in lean *** addition,gAcrp potentiated the therapeutic effectiveness of ADSC in a mouse model of DSS-induced ***,while obesity inhibited the glycolytic capacity of MSC,gAcrp treatment induced a metabolic shift toward glycolysis through activation of adiponectin receptor type 1/p38 MAPK/hypoxia inducible factor-1a *** findings suggest that activation of adiponectin signaling is a promising strategy for enhancing the therapeutic efficacy of MSC against immune-mediated disorders.

关键词： Adiponectin Adipose-derived stromal cells Colitis Glycolytic induction HIF1a Immunomodulation Mesenchymal stromal cells Obesity

循环三轴试验加载频率和压实度对重塑砂土液化行为的影响

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岩土力学 2024年第6期45卷 1813-1823页

作者： THUY Do Van TIEP Pham duc HIEU nguyen Van THANG Pham Cao 勒奎东技术大学特殊工程技术研究所越南河内越南航空科技协会越南河内

通过对各向同性固结不排水试样进行循环三轴试验,研究了饱和重塑砂土的液化行为。试验采用恒幅正弦载荷,通过测量剪切模量、阻尼比、轴向应变和超孔隙水压力比的变化,评估了加载频率(分别为0.1、0.5、1.0 Hz)和压实度(分别为0.95、0.90... 详细信息

通过对各向同性固结不排水试样进行循环三轴试验,研究了饱和重塑砂土的液化行为。试验采用恒幅正弦载荷,通过测量剪切模量、阻尼比、轴向应变和超孔隙水压力比的变化,评估了加载频率(分别为0.1、0.5、1.0 Hz)和压实度(分别为0.95、0.90和0.80)对砂土液化行为的影响。试验结果表明,对于压实度为0.95的砂样,在5000次加载循环中,0.1 Hz的加载频率对液化过程影响甚微;而对于压实度为0.90和0.80的砂样,此频率的影响显著。对于压实度为0.80的砂样,当频率增加到0.5 Hz时几乎一加载就直接发生液化。这表明增加加载频率会加快液化速度,而增加压实度则会减慢液化速度。因此,通过一系列的试验可以模拟现场砂土在不同频率下的动荷载条件。试验结果表明,饱和砂土的液化行为由以下因素决定:(1)试样的压实度越低,液化越容易发生;(2)加载频率越高,液化越容易发生;(3)循环轴向应变越大,发生液化所需的循环次数越少;(4)超孔隙水压力随加载循环次数增加,直至试样完全液化。

关键词：液化行为加载频率循环三轴试验饱和固结不排水条件重塑砂土压实度

Is convenience really king? Comparative evaluation of catastrophic costs due to tuberculosis in the public and private healthcare sectors of Viet Nam: a longitudinal patient cost study

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贫困所致传染病(英文) 2024年第2期13卷 1-12页

作者： nguyen Hoa Binh Quang Vo Luan nguyen Forse Rachel Jeanette Wiemers Anja Maria Christine Huynh Huy Ba Dong Thuy Thi Thu Phan Yen Thi Hoang Creswell Jacob dang Thi Minh Ha nguyen Lan Huu Shedrawy Jad L?nnroth Knut nguyen Tuan Dinh Van Dinh Luong Annerstedt Kristi Sidney Codlin Andrew James National Lung Hospital Ha Noi Viet Nam Friends for International TB Relief Ha Noi Viet Nam Department of Global Public Health WHO Collaboration Centre On Tuberculosis and Social Medicine Karolinska Institute Stockholm Sweden Stop TB Partnership Geneva Switzerland Pham Ngoc Thach Hospital Ho Chi Minh City Viet Nam

Background In Viet Nam, tuberculosis (TB) represents a devastating life-event with an exorbitant price tag, partly due to lost income from daily directly observed therapy in public sector care. Thus, persons with TB may seek care in the private sector for its flexibility, convenience, and privacy. Our study aimed to measure income changes, costs and catastrophic cost incurrence among TB-affected households in the public and private *** Between October 2020 and March 2022, we conducted 110 longitudinal patient cost interviews, among 50 patients privately treated for TB and 60 TB patients treated by the National TB Program (NTP) in Ha Noi, Hai Phong and Ho Chi Minh City, Viet Nam. Using a local adaptation of the WHO TB patient cost survey tool, participants were interviewed during the intensive phase, continuation phase and post-treatment. We compared income levels, direct and indirect treatment costs, catastrophic costs using Wilcoxon rank-sum and chi-squared tests and associated risk factors between the two cohorts using multivariate *** The pre-treatment median monthly household income was significantly higher in the private sector versus NTP cohort (USD 868 vs USD 578;P=0.010). However, private sector treatment was also significantly costlier (USD 2075 vs USD 1313;P=0.005), driven by direct medical costs which were 4.6 times higher than costs reported by NTP participants (USD 754 vs USD 164;P<0.001). This resulted in no significant difference in catastrophic costs between the two cohorts (Private: 55% vs NTP: 52%;P=0.675). Factors associated with catastrophic cost included being a single-person household [adjusted odds ratio [(aOR=13.71; 95% confidence interval (CI): 1.36–138.14;P=0.026], unemployment during treatment (aOR=10.86; 95%CI: 2.64–44.60;P<0.001) and experiencing TB-related stigma (aOR=37.90; 95%CI: 1.72–831.73;P=0.021).Conclusions Persons with TB in Viet Nam face similarly high risk of catastrophic costs whether treated in the

关键词： Tuberculosis Patient cost Catastrophic cost Private sector Comparative analysis Viet Nam

Push forward LC-MS-based therapeutic drug monitoring and pharmacometabolomics for anti-tuberculosis precision dosing and comprehensive clinical management

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Journal of Pharmaceutical Analysis 2024年第1期14卷 16-38页

作者： nguyen Quang Thu nguyen Tran Nam Tien nguyen Thi Hai Yen Thuc-Huy Duong nguyen Phuoc Long Huy Truong nguyen Department of Pharmacology and PharmacoGenomics Research Center Inje University College of MedicineBusan47392Republic of Korea Department of Chemistry University of EducationHo Chi Minh City700000Viet Nam Faculty of Pharmacy Ton Duc Thang UniversityHo Chi Minh City700000Viet Nam

The spread of tuberculosis(TB),especially multidrug-resistant TB and extensively drug-resistant TB,has strongly motivated the research and development of new anti-TB *** strategies to facilitate drug combinations,including pharmacokinetics-guided dose optimization and toxicology studies of first-and second-line anti-TB drugs have also been introduced and *** chromatography-mass spectrometry(LC-MS)has arguably become the gold standard in the analysis of both endo-and exo-genous *** technique has been applied successfully not only for therapeutic drug monitoring(TDM)but also for pharmacometabolomics *** improves the effectiveness of treatment,reduces adverse drug reactions,and the likelihood of drug resistance development in TB patients by determining dosage regimens that produce concentrations within the therapeutic target *** on TDM,the dose would be optimized individually to achieve favorable *** is essential in generating and validating hypotheses regarding the metabolism of anti-TB drugs,aiding in the discovery of potential biomarkers for TB diagnostics,treatment monitoring,and outcome *** article highlighted the current progresses in TDM of anti-TB drugs based on LC-MS bioassay in the last two ***,we discussed the advantages and disadvantages of this technique in practical *** pressing need for non-invasive sampling approaches and stability studies of anti-TB drugs was ***,we provided perspectives on the prospects of combining LC-MS-based TDM and pharmacometabolomics with other advanced strategies(pharmacometrics,drug and vaccine developments,machine learning/artificial intelligence,among others)to encapsulate in an all-inclusive approach to improve treatment outcomes of TB patients.

关键词： Tuberculosis Therapeutic drug monitoring LC-MS MIPD Pharmacometabolomics Precision medicine