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Enhancing global hepatocellular carcinoma management:Bridging Eastern and Western perspectives on dexamethasone and Nacetylcysteine before transarterial chemoembolization

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World Journal of Gastroenterology 2024年第47期30卷 4983-4990页

作者： Thang Viet Luong Nam Van Duc nguyen Linh Duy Le Hieu nguyen Hoang Minh Hai nguyen ngoc Dang Department of Internal Medicine University of Medicine and PharmacyHue UniversityHue 530000Viet Nam Department of Diagnostic Imaging University of Medicine and PharmacyHue UniversityHue 530000Viet Nam Faculty of Medicine Duy Tan UniversityDa Nang 550000Viet Nam

This article explores the integration of Eastern and Western perspectives on the use of dexamethasone and N-acetylcysteine as premedications in transarterial chemoembolization for hepatocellular carcinoma(HCC).By examining key concerns raised by Western researchers,particularly regarding the different etiologies of liver cirrhosis,and contrasting them with robust clinical data from Asia,this article highlights the necessity for region-specific research and proposes future directions for global HCC management.

关键词： Hepatocellular carcinoma Transarterial chemoembolization Dexamethasone N-acetylcysteine East-West perspectives Post-embolization syndrome

Assessing Asian Economies Renewable Energy Consumption Efficiency Using DEA with Undesirable Output

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Computer Systems Science & Engineering 2022年第10期43卷 347-362页

作者： Chia-Nan Wang ngoc-Ai-Thy nguyen Thanh-Tuan Dang Jing-Wein Wang Department of Industrial Engineering and Management National Kaohsiung University of Science and TechnologyKaohsiung80778Taiwan Department of Logistics and Supply Chain Management Hong Bang International UniversityHo Chi Minh723000Vietnam Institute of Photonics Engineering National Kaohsiung University of Science and TechnologyKaohsiung80778Taiwan

Along with vast non-fossil potential and significant expertise,there is a question of whether Asian nations are attaining efficient consumption and exploitation of renewable *** this perspective,the paper aims to evaluate the efficiency of 14 potential Asia countries in renewable energy consumption during the six-year periods(2014-2019).In analyzing the performance of the renewable energy sector,the data envelopment analysis(DEA)with an undesirable output model approach has been widely utilized to measure the efficiency of peer units compared with the best practice *** consider four inputs and two outputs to a DEA-based efficiency *** force,total energy consumption,share of renewable energy,and total renewable energy capacity are *** outputs consist of CO_(2)emissions as an undesirable output and gross domestic product as a desirable *** results show that United Arab Emirates,Saudi Arabia,Japan,and South Korea consistently outperform in the evaluation,achieving perfect efficiency scores during the research *** is found to have the lowest average efficiency of renewable energy utilization.

关键词： Asia renewable energy efficiency frontier data envelopment analysis bad output

Coordinated Expression of Cytosolic and Chloroplastic Glutamine Synthetase During Reproductive Stage and Its Impact in GS1 RNAi Transgenic Rice

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Rice science 2018年第5期25卷 250-260页

作者： Tieu-ngoc nguyen LE Beomgi LEE Kyoungwhan BACK Young Soon KIM Hyeonsook CHEONG Department of Biotechnology Chonnam National University Department of Life Science Chosun University

To understand the reallocation of organic nitrogen from leaf to the flower head of rice, the role of glutamine synthetase （GS） was investigated by characterizing GS1 RNAi transgenic rice, which revealed a significant reduction in panicle number and number of seeds per panicle. We observed the expression of GS isotypes at transcriptional and protein levels in flag leaves, leaf sheaths and panicles at three different flower development stages. The mRNA expression of GS1;1 was clearly suppressed in flag leaves, especially at the flowering stage. GS1 protein was barely detectable in flag leaves until the flowering stage, while GS1 protein was compromised in the leaf sheath and panicle, with transient expression of GS2 protein at the flowering stage. The glutamine level in transgenic plants was significantly reduced in both flag leaves and panicles, but ammonium was highly accumulated. The level of other amino acids, including aspartate and asparagine, tended to be higher in RNAi transgenic plants than the wild type plants during the reproductive stage. In addition, accumulation of toxic ammonium in panicles with low glutamine level might have caused low seed-setting in the transgenic rice. These results indicated that nitrogen reallocation was critical for panicle development, and that multiple GS isotypes functioned cooperatively to complete the rice life cycle when leaf nitrogen was remobilized to the developing reproductive organs.

关键词： ammonium grain yield RNA interference panicle development nitrogen reallocation rice glutamine synthase flowering stage

Understanding gastric metastasis of small cell lung carcinoma:Insights from case reports and clinical implications

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World Journal of Gastroenterology 2024年第47期30卷 5092-5096页

作者： Nhi Thi Y nguyen Thang Viet Luong Dat Xuan nguyen Linh Duy Le Hai nguyen ngoc Dang Department of Internal Medicine University of Medicine and PharmacyHue UniversityHue 530000Viet Nam Faculty of Medicine Duy Tan UniversityDa Nang 550000Viet Nam

Small cell lung cancer(SCLC)is a common type of primary lung cancer that contributes to approximately 15%of *** is closely associated with tobacco risk *** is also known as a type of lung cancer that has a high mortality rate within a short time due to its rapid growth rate(with tumor doubling time of 30 days)and its tendency to metastasize early in the disease *** primary sites of metastasis in SCLC are similar to those in other primary lung cancers and often include the brain,bones,adrenal glands,liver,and lymph ***,there are a few clinical reports of uncommon metastases,such as gastric metastasis from *** the incidence of this clinical presentation is very low,reported cases have generally resulted in early mortality due to inadequate *** purpose of this letter is to discuss the knowledge related to gastric metastasis from SCLC and remind clinical doctors not to miss atypical symptoms,thereby providing the right attitude to improve the prognosis for these patients.

关键词： Gastric metastasis Small cell lung cancer Primary lung cancer Immunohistochemistry Clinical cases

Seroprotection after hepatitis B vaccination amongst infants aged between 12 and 24 months in Ho Chi Minh City, Vietnam

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Asian Pacific Journal of Tropical Medicine 2020年第7期13卷 295-300页

作者： Giao Huynh Quang Vinh Bui ngoc Lan nguyen Le An Pham Faculty of Public Health University of Medicine and Pharmacy at Ho Chi Minh CityVietnam Department of Pediatrics University of Medicine and Pharmacy at Ho Chi Minh CityVietnam Department of Microbiology and Parasitology University of Medicine and Pharmacy at Ho Chi Minh CityVietnam Center for training of Family Medicine University of Medicine and Pharmacy at Ho Chi Minh City Vietnam

Objective:To assess levels of HBs Ab amongst infants who received hepatitis B vaccine in the Expanded Program on Immunization in ***:A cross-sectional study was carried out at 16 community health centers from February 2016 to July *** infants were tested for HBs Ab and HBs *** questionnaires were used to collect relevant information about the demographics of the parents/caregivers and their infants after physical ***:A total of 199 eligible infants were selected with a mean age of(17.3±4.5)*** antibody levels with HBs Ab≥10 m IU/m L were detected in 68.3%of *** these,antibody levels from 10 to 99 m IU/m L were 48.5%of those tested and antibody levels≥100 ml U/m L were recorded as 51.5%.No cases were recorded of being infected with hepatitis B *** rate of positive HBs Ab level in those who were not wasting and≥18 months old was less than that among those who were<18 months old(OR 0.49,95%CI:0.26-0.92,P<0.05)while the infants with wasting and<18 months were less likely to be positive HBs Ab than those who were not wasting and of the same age group(OR 0.15,95%CI:0.04-0.55,P<0.05).Conclusions:Seroprotection against hepatitis B virus was low in the infants tested(at 68.3%),which suggests that the hepatitis B vaccine should be administered with one additional dose for infants between 12 and 24 months of age,particularly those with wasting.

关键词： Hepatitis B virus Hepatitis B Vaccine Vaccination Expanded Program on Immunization

Photocatalytic degradation of antibiotic sulfamethizole by visible light activated perovskite LaZnO_(3)

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Journal of Environmental Sciences 2024年第10期144卷 212-224页

作者： Bui The Huy XCuong nguyen Vu Khac Hoang Bui nguyen ngoc Tri Iqra Rabani Nhu Hoa Thi Tran Quang Viet Ly Hai Bang Truong Major of Biomedical Engineering Division of Smart HealthcareCollege of Information Technology and ConvergencePukyong National UniversityBusan 48513Korea Center for Advanced Chemistry Institute of Research and DevelopmentDuy Tan UniversityDa Nang 550000Viet Nam Faculty of Environmental and Chemical Engineering Duy Tan UniversityDa Nang 550000Viet Nam Department of Environment and Energy Sejong UniversitySeoul 05006Korea Lab of Computational Chemistry and Modelling Department of ChemistryFaculty of Natural SciencesQuy Nhon UniversityQuy NhonViet Nam Department of Nanotechnology and Advanced Materials Engineering Sejong UniversitySeoul 05006Korea Faculty of Materials Science and Technology University of ScienceHo Chi Minh City 700000Viet Nam Vietnam National University Ho Chi Minh City 700000Viet Nam Department of Environmental Engineering Seoul National University of Science and TechnologySeoul 01811Korea Optical Materials Research Group Science and Technology Advanced InstituteVan Lang UniversityHo Chi Minh CityViet Nam Faculty of Applied Technology School of TechnologyVan Lang UniversityHo Chi Minh CityViet Nam

In thiswork,the perovskite LaZnO_(3) was synthesized via sol-gel method and applied for photocatalytic treatment of sulfamethizole(SMZ)antibiotics under visible light *** was almost completely degraded(99.2%±0.3%)within 4 hr by photocatalyst LaZnO_(3) at the optimal dosage of 1.1 g/L,with amineralization proportion of 58.7%±0.4%.The efficient performance of LaZnO_(3) can be attributed to itswide-range light absorption and the appropriate energy band edge levels,which facilitate the formation of active agents such as·O_(2)^(−),h^(+),and·*** integration of RP-HPLC/Q-TOF-MS and DFT-based computational techniques revealed three degradation pathways of SMZ,which were initiated by the deamination reaction at the aniline ring,the breakdown of the sulfonamidemoieties,and a process known as Smile-type rearrangement and SO2 *** toxicity of SMZ and the intermediateswere analyzed by quantitative structure activity relationship(QSAR),indicating the effectiveness of LaZnO_(3)-based photocatalysis in preventing secondary pollution of the intermediates to the ecosystem during the degradation *** visible-light-activated photocatalyst LaZnO_(3) exhibited efficient performance in the occurrence of inorganic anions and maintained high durability across multiple recycling tests,making it a promising candidate for practical antibiotic treatment.

关键词： Perovskite Antibiotics Photocatalysis Density functional theory Toxicity

N4-methylcytidine ribosomal RNA methylation in chloroplasts is crucial for chloroplast function,development,and abscisic acid response in Arabidopsis

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Journal of Integrative Plant Biology 2021年第3期63卷 570-582页

作者： Le nguyen Tieu ngoc Su Jung Park Trinh Thi Huong Kwang Ho Lee Hunseung Kang Department of Applied Biology College of Agriculture and Life SciencesChonnam National UniversityGwangju 61186Republic of Korea Faculty of Forestry Agriculture Tay Nguyen UniversityBuonMaThuotDakLak63000Vietnam Center for Research Facilities Chonnam National UniversityGwangju 61186Republic of Korea

Although the essential role of messenger RNA methylation in the nucleus is increasingly understood,the nature of ribosomal RNA(rRNA)methyltransferases and the role of rRNA methylation in chloroplasts remain largely unknown.A recent study revealed that CMAL(for Chloroplast mraW-Like)is a chloroplast-localized rRNA methyltransferase that is responsible for N4-methylcytidine(m^(4)C)in 16S chloroplast rRNA in Arabidopsis *** this study,we further examined the role of CMAL in chloroplast biogenesis and function,development,and hormone *** cmal mutant showed reduced chlorophyll biosynthesis,photosynthetic activity,and growth-defect phenotypes,including severely stunted stems,fewer siliques,and lower seed *** cmal mutant was hypersensitive to chloroplast translation inhibitors,such as lincomycin and erythromycin,indicating that the m^(4)C methylation defect in the 16S rRNA leads to a reduced translational activity in ***,the stunted stem of the cmal mutant was partially rescued by exogenous gibberellic acid or *** cmal mutant grew poorer than wild type,whereas the CMAL-overexpressing transgenic Arabidopsis plants grew better than wild type in the presence of abscisic ***,these results indicate that CMAL is an indispensable rRNA methyltransferase in chloroplasts and is crucial for chloroplast biogenesis and function,photosynthesis,and hormone response during plant growth and development.

关键词： abiotic stress Arabidopsis chloroplast CMAL RNA methylation rRNA methylation

Effects of parental age on offspring growth and survival in both wild and domesticated strains of bighead catfish(Clarias macrocephalus Günther,1864)

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Aquaculture and Fisheries 2023年第2期8卷 141-147页

作者： Thuy Yen Duong Thet Su Win Thi ngoc Tran nguyen College of Aquaculture and Fisheries Can Tho UniversityCan Tho920000Viet Nam International Master Program in Aquaculture Course 4Can Tho UniversityCan Tho920000Viet Nam

Understanding the relationship between fish parental age and offspring performance over their life cycle is crucial for *** study investigates the effect of parental age for both 1-and 2-year-old fish on the growth and survival rates of their larval to grow-out stages for two wild and domesticated strains of bighead catfish(Clarias macrocephalus).Fish were sampled from the Vietnamese Mekong Delta where wild adult fish were collected from a conservation area in Ca Mau Province and domesticated fish were taken from a hatchery in Can *** offspring treatments of 1-and 2-year-old broodstock strains were reared for 3 successive periods:40 days for fingerling rearing in static tanks with water exchange,60 days for juveniles,and 90 days for grow-out in recirculating *** final weight of fish at 190 days varied from 96.7 to 144.7 *** growth of offspring was not affected by parental age(P>0.05),over the 3 rearing ***,the domesticated fish strain showed significantly better growth rates than the wild fish strain(P<0.05).Feed conversion ratios were comparable across fish *** rates did not differ at the fingerling(21.8%-36.4%)and juvenile(69.0%-73.3%)***,significant differences were found at the grow-out stage(69.3%-84.0%),with offspring from 2-year-old parents of both strains having greater survival ***,1-and 2-year-old fish appear to be suitable for bighead catfish breeders.

关键词： Parental age Clarias catfish Fish growth Strain evaluation Wild broodstock

Morphology and kinematics of the gas envelope of the Mira binary W Aquilae

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Research in Astronomy and Astrophysics 2016年第7期16卷 47-54页

作者： Do Thi Hoai Pham Tuyet Nhung Pham ngoc Diep nguyen Thi Phuong Pham Tuan-Anh nguyen Thi Thao Pierre Darriulat Department of Astrophysics Vietnam National Satellite CenterVAST

We analyse ALMA observations of the12CO（3-2） emission of the circumstellar envelope（CSE）of the Mira variable binary star W Aql. These provide, for the first time, spatially resolved Doppler velocity spectra of the CSE up to angular distances to the central star ofy nature of the observations（only five minutes in each of～5′′（meaning some 2000 AU）. The explorator two different configurations） does not allow for a detailed modelling of the properties of the CSE but provides important qualitative information on its morphology and kinematics. Emission is found to be enhanced along an axis moving from east/west to north-east/south-west when the angular distance from the central star projected on the plane of the sky increases from zero to four arcseconds. In parallel, the Doppler velocity distribution displays asymmetry along an axis moving from east/west to north-west/south-east. The results are discussed in the context of earlier observations, in particular of the dust morphology.

关键词： stars AGB and post-AGB (stars ) circumstellar matter stars individual(W Aql) stars mass-loss radio lines stars