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The protean manifestations of central nervous system IgG4-related hypertrophic pachymeningitis:a report of two cases

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Chinese Neurosurgical Journal 2021年第4期7卷 306-312页

作者： Peter Y.M.Woo Ben C.F.Ng June H.M.Wong Oliver K.S.Ng Timothy S.K.Chan ngai-fung kwok Kwong-Yau Chan Department of Neurosurgery Kwong Wah HospitalHong KongHong KongChina Department of Internal Medicine Caritas Medical CenterHong KongHong KongChina Department of Pathology Kwong Wah Hospital25 Waterloo RoadYaumateiHong KongHong KongChina Department of Neurosurgery Queen Elizabeth HospitalHong KongHong KongChina

Background:IgG4-related hypertrophic pachymeningitis is a relative newly recognized and rare manifestation of IgG4-related disease,an immune-mediated fibroinflammatory tumefactive *** than 80 patients have been reported in the literature,and it can mimic common neurosurgical *** describe the clinical presentation of two patients that were initially considered to have a subdural collection,tuberculous meningitis,and a cervical spinal meningioma,but were eventually diagnosed with this *** presentation:Two ethnic Chinese men,86 and 62 years old,experienced a 4-week history of *** patients had a history of autoimmune disease,namely glomerulonephritis and Grave’s disease,*** resonance brain imaging revealed diffuse dural thickening with the latter patient exhibiting homogeneous and intense gadolinium-contrast *** the 86-year-old patient also had progressive bilateral visual loss,giant cell arteritis was suspected and a 2-week course of glucocorticoid therapy was prescribed,but his symptoms failed to *** 62-year-old patient also had accompanying low-grade fever and was treated empirically as having tuberculous meningitis although there were no confirmatory microbiological *** patient further developed right hemiparesis,and additional imaging revealed a C4/5 intradural-extramedullary contrast-enhancing lesion resembling a meningioma causing cord *** patients underwent neurosurgical intervention with the former undergoing a dural biopsy and the latter having the cervical lesion *** final diagnosis was IgG4-related hypertrophic pachymeningitis with the hallmark histological features of lymphoplasmacytic infiltration of IgG4+plasma cells,storiform fibrosis,and obliterative *** addition,their serum IgG4 levels were elevated(i.e.,>135 mg/dL).Both patients received at least 6 months of glucocorticoid therapy while the latter also had *** symptom

关键词： Hypertrophic pachymeningitis IgG4-related disease IgG4-related sclerosing disease Central nervous system

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Using MRE to Quantitatively Measure the Effects of Acupuncture on Muscle Stiffness

Using MRE to Quantitatively Measure the Effects of Acupunctu...

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第十四届全国中药和天然药物学术研讨会

作者： Derek Hang Chun kwok Geng Li Jason Wan Man fung Kiu ngai So Ye Zhang Ying Zheng Sun Yiu Chong Simon Sze Man Yeung Qi Yuan Ma Time Medical Limited

＜正＞Background Magnetic Resonance Elastography（MRE）is a non-invasive technique that quantitatively measures tissue stiffness[1].It consists of generating shear waves in tissue;acquiring MR images of the induced sh...

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The influence of a walking exercise program on the balance of residents ambulating with stick in a local care and attention home

The influence of a walking exercise program on the balance o...

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中国康复医学会第二届全国康复治疗学术会议

作者： ngai Rebecca Au-Yeung Stephanie Playsiotherapy Department fung Yiu King Hospital Hong Kong Departement of Rehabilitation Sciences Hong Kong Polytechnic University

＜正＞Objective:The balance of elderly people deserves special attention because of its importance in functional mobility and safety （Berg 1989）. The objective of the study is to investigate the effect of a task - specific walking exercise program and its carry - over effect on the balance of residents ambulating with stick in a care and attention home. Method:This study was of the pretest - posttest control group design. Thirty subjects of stick ambulators living in a

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