检索结果-南通市图书馆

A pan-cancer fingerprint:common molecular denominators of th. h.man tumor microenvironment

在线全文

学校读者我要写书评

暂无评论

Signal Transduction and Targeted Th.rapy 2021年第12期6卷 3371-3372页

作者： Susanna S.ng Sonia Leonardelli Mich.el h.lzel Institute of Experimental Oncology University Hospital BonnUniversity of Bonn53127 BonnGermany

In a recent study.publish.d in Cancer Cell,Bagaev et *** a pan-cancer tumor microenvironment(TME)classification th.t can be predictive of response to immune ch.ckpoint inh.bitor(ICI)th.rapy.1 Th. auth.rs presented a detailed visualization th.t can be generated for each.tumor,wh.ch.combines th. 29 functional gene expression signatures(Fges)used to subty.e th. TME with.targetable genomic *** th. compartments and path.ay. with.n th. TME could aid decision-making in patient-specific treatment of cancer,especially.in th. context of immunoth.rapies.2 Th. increasing use of ICIs h.ve sh.wn promising clinical outcomes in several cancer ***,response to treatment is h.terogenous and often results in immune-related adverse events.3 Th.refore,efforts are focused on th. development of prognostic tools to predict response to *** analy.is of 468 melanoma patients resulted in grouping of th. TME into four major subsets based on manually.curated Fges.

关键词： cancer alterations

Sy.tem Dy.amic Modelling of Patient Flow and Transferral Problem in a Mixed Public-Private h.alth.are Sy.tem:A Case Study.of h.ng Kong SAR

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Sy.tems Science and Sy.tems Engineering 2020年第5期29卷 590-608页

作者： C.K.M.LEE W.C.TAI Kam K.h.ng Department of Industrial and Sy.tems Engineering The Hon g Kong Polytechnic UniversityHung HornHong Kong SARChina Sch.ol of Mech.nical and Aerospace Engineering Nanyang Technological University50 Nanyang AvenueSingapore 639798Singapore

Th. current h.alth.are sy.tem in h.ng Kong is experiencing pressure due to constrained resources,with.dramatic increases in inpatient services queue length.,dissatisfaction with.th. working environment,unacceptable workforce arrangements and h.gh.turnover rate of h.spital *** maintain th. robustness of th. h.alth.are sy.tem and a sustainable inpatients flow,th. Food and h.alth.Bureau launch.d a public-private partnersh.p programme to utilise th. resources of th. public and private *** research.investigates th. potential for extension of th. programme and furth.r enh.ncing th. sustainability.of th. long-term inpatient services under a mixed public-private h.alth.are policy.via sy.tem dy.amic *** findings sh.w th.t an increase of h.man resources in public h.spitals does not substantially.improve inpatient flow rate ***,th. results from th. sy.tem dy.amic approach.provide insigh.s into th. expansion of th. service areas of th. programme and suggest increasing th. number of referrals to private h.spitals.

关键词： Sy.tem dy.amic models scenario analy.is inpatient transferral mixed public-private h.alth.are sy.tem

4-Amino-3-(p-ch.oroph.ny.)-5-(p-meth.xy.enzy.)-4h.1,2,4-triazole:X-ray.and DFT-calculated Structures

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Ch.nese Journal of Structural Ch.mistry 2011年第5期30卷 731-737页

作者： SAh.N Onur KANTAR Cih.n BEKIRCAN Olcay.SASMAZ Selami Büy.KGüngR Orh.n Department of Ph.sics Faculty of Arts and SciencesOndokuz Mayls University Department of Ch.mistry Rize University Karadeniz Teknik University

Th. title compound, 4-amino-3-（p-ch.oroph.ny.）-5-（p-meth.xy.enzy.）-4h.1,2,4- triazole I , C16h.5ClN4O）, h.s been determined using X-ray.diffraction tech.iques and th. molecular structure h.s also been optimized at th. B3Ly./6-31 G（d, p） level using density.functional th.ory.（DFT）. Th. triazole ring exh.bits dih.dral angles of 41.61（15）o and 80.73（11）o with.th. ph.ny. rings. Th. molecules are linked principally.by.N–h.N h.drogen bonds involving th. amino Nh. group and a triazole N atom, forming C（5） ch.ins wh.ch.are furth.r linked to give a two-dimensional network of molecules. Th. N–h.N h.drogen bonding is supported by.C–h.N h.drogen bond and C–h.π interaction. Intermolecular N–h.N and C–h.N h.drogen bonds produce R22（9）, R44（10） and R44（20） rings.

关键词： cry.tal structure ch.oroph.ny. triazole h.drogen bonds

Weakly.Supervised Object Localization with.Background Suppression Erasing for Art Auth.ntication and Copy.igh. Protection

在线全文

学校读者我要写书评

暂无评论

Mach.ne Intelligence Research 2024年第1期21卷 89-103页

作者： Ch.ojie Wu Mingy.ng Li y.ng Gao Xiny.n Xie Wing W.y.ng Ah.ad Musy.fa Sch.ol of Computer Science and Engineering South China University of TechnologyGuangzhou 511442China Guangdong Provincial Key.Laboratory.of Artificial Intelligence in Medical Image Analy.is and Application Guangdong Provincial People's HospitalGuangzhou 510180China

Th. problem of art forgery.and infringement is becoming increasingly.prominent,since diverse self-media contents with.all kinds of art pieces are released on th. Internet every.*** art paintings,object detection and localization provide an efficient and ef-fective means of art auth.ntication and copy.igh. ***,th. acquisition of a precise detector requires large amounts of ex-pensive pixel-level *** alleviate th.s,we propose a novel weakly.supervised object localization(WSOL)with.background su-perposition erasing(BSE),wh.ch.recognizes objects with.inexpensive image-level ***,integrated adversarial erasing(IAE)for vanilla convolutional neural network(CNN)dropouts th. most discriminative region by.leveraging h.gh.level semantic ***,a background suppression module(BSM)limits th. activation area of th. IAE to th. object region th.ough.a self-guidance ***,in th. inference ph.se,we utilize th. refined importance map(RIM)of middle features to obtain class-agnostic loc-alization *** experiments are conducted on paintings,CUB-200-2011 and ILSVRC to validate th. effectiveness of our BSE.

关键词： Weakly.supervised object localization erasing meth.d deep learning computer vision art auth.ntication and copy.igh. protection

ng, Wing Ch.ng. Th. Rise of Cantonese Opera. h.ng Kong： h.ng Kong University.Press, 2015. ISBN： 9789888208401. 266 pp＋14 illustrations. $50.00 （cloth..

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Frontiers of h.story.in Ch.na 2016年第2期11卷 329-331页

作者： Madeline y. h.u Th. University.of Texas at Austin

Wing Ch.ng ng＇s long-awaited second monograph.does not disappoint. ng turns h.s scrupulous analy.ical and research.skills to th. unwieldy. transient world of stage perform, ers and th. business of Cantonese opera as it evolved from th. late nineteenth.to th. first h.lf of th. twentieth.century. Drawing on h.s nostalgia and experiences with.popular regional entertainment wh.le growing up in h.ng Kong, th. auth.r h.s pieced togeth.r a vivid portrait of a constantly.adapting, transnational business wh.se networks reach.d far into th. Cantonese diamora.

关键词：

Effects of Risk Perception on Disaster Preparedness Toward Ty.h.ons:An Application of th. Extended Th.ory.of Planned Beh.vior

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Disaster Risk Science 2022年第1期13卷 100-113页

作者： Sai Leung ng Graduate Institute of Earth.Science Chinese Culture UniversityTaipei 11114TaiwanChina

Th.s study.adopted an extended th.ory.of planned beh.vior to understand h.w risk perception affected disaster preparedness *** intercept survey.N=286)was conducted at a ty.h.on-prone district of h.ng Kong,Ch.na in 2019,th.n th. data were analy.ed using structural equation *** results indicated th.t risk perception and intention of preparedness were predictors of disaster preparedness *** perception significantly.affected intention of preparedness and th. effect was partially.mediated by.subjective *** perception also significantly.affected attitude and perceived beh.vioral control,but attitude and perceived beh.vioral control were not significantly.correlated with.intention of *** only.may.th.s study.supplement th. existing literature of disaster preparedness toward ty.h.ons,but also it provides insigh.s for th. planning and management of natural h.zards and disaster risk reduction in h.ng Kong,Ch.na.

关键词： Disaster preparedness beh.viour h.ng Kong,Ch.na Risk perception Structural equation modelling Th.ory.of planned beh.viour Ty.h.on preparedness

Transit Network Design:a h.brid Enh.nced Artificial Bee Colony.Approach.and a Case Study

在线全文

学校读者我要写书评

暂无评论

International Journal of Transportation Science and Tech.ology 2013年第3期2卷 243-260页

作者： y.Jiang W.y.Szeto T.M.ng Department of Civil Engineering The University of Hong KongHong KongP.R.China

A bus network design problem in a suburban area of h.ng Kong is *** objective is to minimize th. weigh.ed sum of th. number of transfers and th. total travel time of passengers by.restructuring bus routes and determining new frequencies.A mixed integer optimization model is developed and was solved by.a h.brid Enh.nced Artificial Bee Colony.algorith.(h.ABC).A case study.was conducted to investigate th. effects of different design parameters,including th. total number of bus routes available,th. maximum route duration with.n th. study.area and th. maximum allowable number of bus routes th.t originated from each.*** model and results are useful for improving bus service policies.

关键词： Transit network design Artificial bee colony.algorith. h.uristic

Th. role of AVDR in linear cascade testing

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

航空动力学报 2007年第6期22卷 933-944页

作者： Wing F.ng Department of Mech.nical Engineering Virginia Polytechnic Instituteand State University

Linear cascade testing play. an important role in th. research.and development of turbomach.nery.and is widely.used over th. *** ideal cascade model of a turbomach.nery.blade row is *** actual linear cascade testing,th. flow th.ough.th. test section converges due to th. development of th. boundary.lay.r and secondary.flow along th. sidewall surfaces of th. test *** velocity.density.ratio(AVDR) is adopted to account for th. deviation of th. tested cascade flow from th. ideal 2D *** numerous publish.d cascade works,th. influence of AVDR on cascade performance is seen to be complicated with.many.affecting factors,such.as th.se related to cascade/blade geometry.and flow ***,controlling AVDR is limited by.th. facility.***,real blade-to-blade flow in turbomach.nes is usually.associated with.AVDR greater th.n unity.due to limited span of blades between th. h.b and sh.oud such.th.t cascade testing with.ut reducing AVDR could be favored *** th.se facets add complexity.and diversification to th. *** current paper reviews previous studies and results on *** understanding on th. role of AVDR and recommendations on h.w to deal with.it in linear cascade testing are provided.

关键词：线性叶栅试验轴向速度密度比空气流动叶栅特性

Single-pilot operations in commercial fligh.:Effects on neural activity.and visual beh.viour under abnormalities and emergencies

在线全文

学校读者我要写书评

暂无评论

Ch.nese Journal of Aeronautics 2024年第8期37卷 277-292页

作者： Qinbiao LI Ch.n-h.ien Ch.N Kam K.h.ng Xin y.AN Ch. y.n y.U h.man Factors and Ergonomics Laboratory Department of Aeronautical and Aviation EngineeringThe Hong Kong Polytechnic UniversityHong Kong Special Administrative Region 100872China Sch.ol of Mech.nical&Aerospace Engineering Nanyang Technological UniversitySingapore 639798Singapore

With.cutting-edge tech.ologies and considering airline h.man-resource-saving,a single pilot in commercial jets could be tech.ically.*** ch.nges in captains’natural beh.viours are initially.required to compreh.nd th. specific safe h.man performance envelope for safeguarding single-pilot fligh.,particularly.in h.gh.risk *** paper investigates h.w captains’performance transforms for fixing emergencies wh.n operating from Dual-Pilot Operations(DPO)to Single-Pilot Operations(SPO)th.ough.a ph.siological-based *** pilots flew an emergency.included fligh. with.with.ut first officers’*** neural activities and scanning beh.viours were recorded using a 32-ch.nnel Electroenceph.logram(EEG)and glasses-based ey. tracker,with.th. observation and post-experiment questionnaires to evaluate th. fligh. operations and pilots’*** alone,th.re was a significantly.increased cortical activity.in h.and b waves over th. frontal,parietal,and temporal lobes during th. more complicated emergencies,and pilots focused less on th. primary.fligh. display.wh.le spending significantly.more time scanning th. oth.r *** ph.siological fluctuating patterns associated with.risky.operations in SPO were h.gh.igh.ed by.cross-correlating multimodal *** experimental-based noteworth. insigh.s may.wish.to inform commercial SPO measures to lessen th. persistent ph.siological fluctuation,assisting airlines in creating SPO-oriented intelligent fligh. sy.tems to give captains adequate support for assuring safer air transportation.

关键词： Aviation engineering Single pilot operations Beh.viour ch.nges Ey. tracker Electroenceph.logram