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External validation of the Moroccan Arabic version of the European Organization for Research and Treatment of Cancer colorectal(CR29)module:Monocentric study

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World Journal of Methodology 2023年第4期13卷 259-271页

作者： Houda Bachri Hajar Essangri nezha el bahaoui Amine Benkabbou Raouf Mohsine Anass Mohammed Majbar Amine Souadka Surgical Oncology Department National Institute of OncologyMohammed Vth University in RabatRabat 10100Morocco Gynecology oncology Department Royal London HospitalBarts NHS HealthLondon SE186EYUnited Kingdom

BACKGROUND Quality of life(QoL)outcomes are a focal endpoint of cancer treatment *** To externally validate the Moroccan Arabic version of the European Organization for Research and Treatment of Cancer(EORTC)QoL Questionnaire(QLQ)for colorectal cancer(CRC)patients(CR29).METHODS Both Moroccan Arabic modules of QLQ-CR29 and QLQ-C30 were administered to Moroccan *** properties were retested by measuring Cronbach’s alpha coefficient for reliability and Intraclass correlation coefficient(ICC)to examine test-retest *** multitrait-scaling analysis was performed to demonstrate the validity of the instrument and known-groups comparison was used to test the score’s ability to discriminate between different groups of *** In total,221 patients were included in our study and 34 patients completed the questionnaire *** Urinary Frequency scale and Stool Frequency scale had good internal consistency with alpha Cronbach coefficients of 0.79 and 0.83 respectively,while the same coefficients were moderately lower for the Blood and Mucus in Stool scale(0.61)and the Body Image scale(0.67).The ICCs ranged from 0.88 to 1 indicating good to excellent *** multitrait scaling analyses,the criterion for item convergent and divergent validity was *** known-group comparison showed statistically significant differences between patients according to age,gender,stoma status,tumor location,and *** The Moroccan Arabic version of the EORTC QLQ-CR29 is a valid and reliable tool that can be used safely for research and clinical purposes in Moroccan CRC patients.

关键词： Rectal neoplasm Colorectal cancer Health-related quality of life Patient reported outcome measures European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-CR29 European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-C30

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Geochemical characterization of rare earth elements in sediment profiles from the Oualida lagoon(Morocco)

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Acta Geochimica 2023年第6期42卷 1051-1064页

作者： nezha Mejjad Abdelmourhit Laissaoui Ouafa el Hammoumi Ahmed Fekri Hamid Amsil National Center for Energy Sciences and Nuclear Techniques(CNESTEN)RabatMorocco LGAGE Faculty of Sciences Ben M'sikUniversity of Hassan IICasablancaMorocco

The present work assesses the temporal distribution pattern and geochemical changes of rare earth elements and Yttrium, Scandium, Thorium, and Uranium delivery into the Oualidia lagoon. Two sediment cores were retrieved from the Oualidia lagoon and analyzed using neutron activation analysis. The results indicated that heavy rare earth elements are slightly enriched the sediment cores over light rare earth elements. The highest values of REEs were recorded in the top layers of the cores and depleted with depth, suggesting a possible change in factors controlling their accumulation, including mechanical, chemical, and environmental parameters such as weathering intensity, grain size, and Fe-Mn oxides. The sediments display positive Ce anomalies, which are probably related to the submarine weathering process and detrital input. Noting also the variation of hydrodynamics conditions and confinement of the upstream part of the lagoon played a key role in changing the sediment ***, further investigation of REEs origin in the Oualidia lagoon sediment is required to identify their sources,provenances, and the factors controlling their spatial and vertical distributions. However, these results provide baseline data of occurring changes in REEs geochemical composition and constitute a typical study case to understand the link between sedimentary and geochemistry processes in a lagoonal ecosystem.

关键词： Geochemical characterization Rare earth elements Sediment Oualidia lagoon

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Renormalized Solutions of Nonlinear Parabolic Equations in Weigthed Variable-Exponent Space

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Journal of Partial Differential Equations 2015年第3期28卷 225-252页

作者： YOUSSEF Akdim CHAKIR Allalou nezha el gorch Laboratory LSL Faculty Polydisciplinary of Taza. University Sidi Mohamed BenAbdellah P. O. Box 1223 Taza Gare Marocco.

This article is devoted to study the existence of renormalized solutions for the nonlinear p （x）-parabolic problem in the Weighted-Variable-Exponent Sobolev spaces, without the sign condition and the coercivity cond... 详细信息

关键词： Weighted variable exponent Lebesgue Sobolev space Young's inequality renormal-ized solution parabolic problems.

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The Ciliate Protist <i>Tetrahymena pyriformis</i>as a Cellular Adhesion Model for the Pathogenic Bacterium <i>Staphylococcus aureus</i>

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Advances in Bioscience and Biotechnology 2017年第12期8卷 491-507页

作者： Bouchra el Khalfi Mohammed Benlahfid Sofia Jarmouni nezha Senhaji Aurelio Serrano Delgado Abdelaziz Soukri Laboratory of Physiopathology Genetics Molecular and Biotechnology (PGMB) Faculty of Sciences Ain Chock Research Center: Health & Biotechnology University Hassan II of Casablanca Casablanca Morocco Laboratory of Genetic and Molecular Pathology (LGPM) Medical School Hassan II University Casablanca Morocco Institute of Biochemistry Vegetal and Photosynthesis (IBVF-CSIC University of Seville) Seville Spain

Staphylococcus aureus is one of the main pathogenic agents responsible for nosocomial and community-acquired bacterial infections. The pathogenicity of this Gram-positive bacterium is ensured by its different adhesion factors. Collagen and the extracellular glycoprotein adhesin are among the Staphylococcus most important virulence factors. It has been shown that most of the S. aureus strains carry the ica operon, responsible for biofilm production. However, the coexpression of the icaA and the icaD genes is necessary for complete biofilm synthesis. The aim of our study was to study a collection of 15 clinical strains of S. aureus from different sources for the presence of can and icaD genes coding intercellular adhesion proteins. We also intended to estimate the strains’ ability to form biofilms by the red Cong method and to test the adhesion ability of S. aureus to the ciliated protist Tetrahymena pyriformis, which we used as a novel cellular adhesion model. Finally, we checked the adhesion’s inhibition capacity of some plants extracts. The molecular detection of adhesion genes revealed that 80% of strains are cna positive, and 73% are icaD positive. Qualitative biofilm production of S. aureus revealed that 66.6% of strains were slime producers. The adhesion test revealed that 20% of strains are strongly adhering to T. pyriformis and that the Clematis cirrhosa extract has an anti-adhering effect of S. aureus to the ciliate T. pyriformis.

关键词： Staphylococcus aureus Adhering Genes (can and icaD) Tetrahymena pyriformis Biofilm Production Plant Extract Anti-Adhesion Effect

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Biotransformation of Ternary Mixture of Organic Industrial Waste into Poultry Feed

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Journal of Agricultural Science and Technology(A) 2018年第3期8卷 171-181页

作者： Lakhal Dounia Bahlaouan Bouchaib Boutaleb Nadia Fathi Asmaa Taiek Taha Abouakil nezha Lazar Said el Antri Said Laboratory of Biochemistry Environment and AgriFood (URAC36) University Hassan Ⅱ 20650 Casablanca Morocco Higher Institutes of the Nursing Professions and Techniques of Health (ISPITS) 20250 Casablanca Morocco

The objective of present study was to produce poultry feed with a best quality using ternary mixture of industrial wastes： fish industry waste, sugar industry waste （molasses） and yeast waste after 15 d biotransformation using response surface methodology to design and analyze the experiment data. Changes in the nutritional quality and biochemical properties viz., pH, dry matter, conductivity, total organic carbon, total nitrogen, phosphorus, trimethylamine, protein, fat, carbohydrate, histamine, aflatoxins and minerals were evaluated during a biotransformation period of 15 d. The experimental findings revealed that the formulation including 50% of fish waste, 12.5% of molasses and 37.50% of yeast waste were found to be best quality poultry waste. It was characterized as odorless, with a stable pH, rich in protein, fat and carbohydrate as well as no alterations of bacteria and absence aflatoxins from the fifth day on ward. The nutritional value of the developed poultry fees was studied on a population of broiler chickens by incorporating with barley flour and eggshell. The product possesses a better nutritional quality comparable to commercially feed.

关键词： Fish waste ternary mixture biotransformation poultry feed response surface

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