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Study of the Types of Refractive Disturbances Obseved during Hyperglycemia in Humans

Open Journal of Ophthalmology 2022年第2期12卷 142-151页

作者： Angue Tatiana Harly Mba Aki Jean Fidèle Nnang Essone nesta ziza ngaila Daniella Nsame Muriel Obono Akoma Olive Rosine Matsanga Félix Ovono Abessolo Department of Surgery and Specialties University of Health Sciences Libreville Gabon Ophthalmology Unit The Mother-Child University Hospital of Libreville Gabon Department of Physiology University of Health Sciences Libreville Gabon Department of Endocrinology and Metabolic Diseases Libreville Gabon Department of Biochemistry University of Health Sciences Libreville Gabon

Introduction: Refractive disturbances have been observed during hyperglycemia. However, there remains controversy as to the types of disturbances that it induces. Objective: To determine the types of refractive disturbances observed during hyperglycemia in humans. Population and Methods: This was an observational and cross-sectional study with an analytical purpose conducted from July to November 2021. Emmetropia, hypermetropia, and myopia as well as blood glucose levels were compared between day 0 (D0) and day 30 (D30) after initiation of hypoglycemic therapy in 222 people (444 eyes) with recently discovered hyperglycemia (Chi-2;p Results: At D0, the mean of blood glucose was 18.1 mmol/L ± 8.2 vs 6.9 mmol/L ± 3.0 at D30 (p = 0.001). At day 0, 80% (n = 355) of eyes were hypermetropic compared to 73.9% (n = 328) at D30 (p = 0.02). At D0, 14.2% of eyes (n = 63) were myopic compared to 11.3% (n = 50) at D30 (p = 0.02). Refraction improved from 0.75 to 1.5D for 34.5% (n = 18) of hypermetropic eyes and 10.2% (n = 2) of myopic eyes. Conclusion: Our results show that hypermetropia is the most common ametropia during hyperglycemia. Moreover, these data suggest that the normalization of blood glucose improves refraction.

关键词： Hyperglycemia Hypermetropia Myopia Hypoglycemic Treatment Libreville

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