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Accumulated Clinical Experiences from Successful Treatment of 1377 Severe and Critically Ill COVID-19 Cases

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Current Medical Science 2020年第4期40卷 597-601页

作者： Yong GAO Hai-bo QIU Shu ZHOU Zhen-ning WANG Jian-chu ZHANG Zheng-liang ZHANG Zhao-xin QIAN Hong-bo WANG Shi-huan YU Yi-feng LUO Ya dan WANG Zhuang LIU Wei-ci WANG Ming JIA Li-ming ZHANG Yu ZHANG Yang JIN Yong ZHANG Yong LIU Zi-hua ZHOU Ying SU Hui-qing LI Wei-min XIAO Kai HUANG Ping HE Gang LI Zhao-hui FU Shi LIU neng xing lin Fan-jun CHENG Union Hospital Tongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China Zhongda Hospital of Souheast University Nanjing 210009China The First Affiliated Hospital of China Medical University Shenyang 110001China The Second Affiliated Hospital of Xi'an Jiaotong University Xi'an 710004China Xiangya Hospital of Zhongnan University Changsha 410008China The First Afiliated Hospital of Harbin Medical University Harbin 150001China The First Affiliated Hospital of Sun Yat-sen University Guangzhou 510080China Beijing Friendship Hospital of Capital Medical University Beijing 100050China Beijing Anzhen Hospital of Capital Medical University Beijing 100029China Beijing Chaoyang Hospital of Capital Medical University Beiing 100020China

Summary:In late December 2019,COVID-19 was firstly recognized in Wuhan,China and spread rapidly to all of the provinces of *** West Campus of Wuhan Union Hospital,the designated hospital to admit and treat the severe and critically ill COVID-19 cases,has treated a large number of such patients with great success and obtained lots of valuable experiences based on the Chinese guideline(V7.0).To standardize and share the treatment procedures of severe and critically ill cases,Wuhan Union Hospital has established a working group and formulated an operational recommendation,including the monitoring,early warning indicators,and several treatment principles for severe and critically ill *** treatment experiences may provide some constructive suggestions for treating the severe and critically ill COVID-19 cases all over the world.

关键词： 2019-nCoV COVID-19 pneumonia treatment guidelines

Research on the influence of quadrupole deformation and continuum effects on the exotic properties of 15,17,19B with the complex momentum representation method

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Nuclear Science and Techniques 2023年第2期34卷 98-108页

作者： Xue‑neng Cao Xian‑Xian Zhou Ming Fu Xin‑xing Shi School of Management Science and Engineering Anhui University of Finance and EconomicsBengbu 233030China School of Mechanics and Optoelectronic Physics Anhui University of Science and TechnologyHuainan 232001China

The properties of exotic nuclei are the focus of the present ***-neutron halo structures of neutron-rich17,19B were experimentally *** studied the formation mechanism of halo phenomena in17,19B using the complex momentum representation method applied to deformation and continuum *** examining the evolution of the weakly bound and resonant levels near the Fermi surface,s–d orbital reversals and certain prolate deformations were *** addition,by analyzing the evolution of the occupation probabilities and density distributions occupied by valence neutrons,we found that the ground state of15B did not exhibit a halo and the ground states of17B and19B exhibited halos at 0.6≤β2≤0.7 and0.3≤β2≤0.7,*** low-l components in the valence levels that are weakly bound or embedded in the continuous spectrum lead to halo formation.

关键词： Quadrupole deformation Resonant states Complex momentum representation Halo

Comparison between double caliper,imaging logs,and array sonic log for determining the in-situ stress direction:A case study from the ultra-deep fractured tight sandstone reservoirs,the Cretaceous Bashijiqike Formation in Keshen8 region of Kuqa depress

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Petroleum Science 2022年第6期19卷 2601-2617页

作者： Song Wang Gui-Wen Wang Dong Li xing-neng Wu Xu Chen Qi-Qi Wang Jun-Tao Cao Yi-lin Zhang State Key Laboratory of Petroleum Resources and Prospecting China University of Petroleum BeijingBeijing102249China College of Geosciences China University of Petroleum BeijingBeijing102249China Research Institute of Petroleum Exploration and Development Tarim Oilfield CompanyCNPCKorla841000XinjiangChina Department of Geological Sciences University of Texas at Austin2275 Speedway Stop C9000AustinTX78712USA

The tight sandstone in the Tarim Basin has the characteristics of large burial depth and development of nature fractures due to concentrated in-situ stress. Identifying the present-day in-situ stress orientation is important in hydrocarbon exploration and development, but also a key scientific question in understanding naturally fractured reservoirs. This paper presents a case study where we integrate various methods using wireline and image-log data, to identify present-day in-situ stress direction of ultra-deep fractured tight sandstone reservoirs, in the Kuqa depression. We discuss the formation mechanism of the elliptical borehole, compares the advantages and applicable conditions of the double caliper method,resistivity image logs and array sonic logs method. The well borehole diameter is measured orthogonally,then the ellipse is fitted, and the in-situ stress orientation is identified by the azimuth of the short-axis borehole, but it fails in the borehole expansion section, the fracture development section and the borehole collapse section. The micro-resistivity image logs method reveals the borehole breakouts azimuth, and also the strike of induced fractures, which are used to determine the orientation of in-situ stress. However, under water-based mud conditions, it’s hard to distinguish natural fractures from induced fractures by image logs. Under oil-based mud conditions, the induced fractures are difficult to identify due to the compromised image quality. As for the sonic log, shear waves will split when passing through an anisotropic formation, shear waves will split during propagation, and the azimuth of fast shear waves is consistent with the orientation of in-situ stress. However, it is usually affected by the anisotropy caused by the excessively fast rotation of the well log tools, so that the azimuth of fast shear wave cannot effectively reflect the orientation of the in-situ stress. Based on comprehensive assessment and comparison, in this paper we

关键词： Fractured tight sandstone In-situ stress Orientation Well logs

Effectiveness of Fiber Bragg Grating monitoring in the centrifugal model test of soil slope under rainfall conditions

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Journal of Mountain Science 2017年第5期14卷 936-947页

作者： LI Long-qi JU neng-pan GUO Yong-xing State Key Laboratory of Geohazard Prevention and Geoenvironment Protection Chengdu University of Technology Chengdu 610059 China College of Environment and Civil Engineering Chengdu University of Technology Chengdu 610059 China School of Machinery and Automation Wuhan University of Science and Technology Wuhan 430081 China

Centrifugal model testsare playing an increasingly importantrolein investigating slope characteristics under rainfall conditions. However, conventional electronic transducers usually fail during centrifugal model tests because of the impacts of limitedtest space, high centrifugal force, and presence of water, with the result that limited valid data is obtained. In this study, Fiber Bragg Grating(FBG) sensing technology is employed in the design and development of displacement gauge, an anchor force gauge and an anti-slide pile moment gauge for use on centrifugal model slopes with and without a retaining structure. The two model slopes were installed and monitored at a centrifugal acceleration of 100 g. The test results show that the sensors developed succeed in capturing the deformation and retaining structure mechanical response of the model slopes during and after rainfall. The deformation curvefor the slope without retaining structure shows a steepresponse that turns gradualfor the slope with retaining structure. Importantly, for the slope with the retaining structure, results suggest that more attention be paid to increase of anchor force and antislide pile moment during rainfall. This study verifies the effectiveness of FBG sensing technology in centrifuge research and presents a new and innovative method for slope model testing under rainfall conditions.

关键词： Fiber Bragg Grating sensing technology Centrifugal model test Soil slope Rainfall conditions Slope displacement

Myeloproliferative neoplasms complicated withβ-thalassemia:Two case report

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World Journal of Clinical Cases 2022年第29期10卷 10655-10662页

作者： neng-Wen Xu lin-Jie Li Department of Hematology College of MedicineLishui HospitalZhejiang UniversityLishui 323000Zhejiang ProvinceChina

BACKGROUND BCR-ABL-negative myeloproliferative neoplasms(MPNs)are clonal hematopoietic stem cell disorders characterized by the proliferation of one or more myeloid lineages and by mutually exclusive JAK2 V617F,CALR,and MPL[A1]*** combination of MPN and thalassemia is extremely *** cases with myeloproliferative neoplasms andβ-thalassemia have been ***,these have not been extensively *** present report describes two cases of myeloproliferative neoplasms complicated withβ-thalassemia and reviews all similar cases reported in the *** SUMMARY We report two patients who were diagnosed with myeloproliferative neoplasms complicated withβ-*** patients had abnormal increases in platelet *** on bone marrow pathology and molecular biology assessment,we made the diagnosis of myeloproliferative neoplasms complicated withβ-*** female patient was given hydroxyurea and interferon,which enabled good control of her blood counts;the male patient was given ruxolitinib tablets,thalidomide tablets,and interferon to control the condition,but the patient poorly responded to drug treatment and died of gastrointestinal bleeding six months *** Given the findings of our cases and the literature review,we hypothesize that myeloproliferative neoplasms complicated withβ-thalassemia can lead to rapid disease progression and a poor prognosis.

关键词： Myeloproliferative Neoplasms β-thalassemia Somatic gene mutation Germline gene mutation Case report

The mitigation negative effect of tunnel-blasting-induced vibrations on constructed tunnel and buildings

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Journal of Coal Science & Engineering(China) 2011年第1期17卷 28-33页

作者： lin Da-neng School of Energy ＆ Safety Engineering Hunan University of Science and Technology Xiangtan 411201 China

Provided the results of a research conducted to investigate the relationships between the empirical vibration attenuation equation of Peak Particle Velocity （PPV） and the Scaled Charge （SC） through testing the blasting-induced vibrations on the spot of Wanshishan tunnel based on 96 vibration recordings. It is found that the maximum charge amount per delay in Wanshishan tunnel excavating is determined by the buildings on the surface and the constructed tunnel nearby. Considering that the repeated blast loading in tunnel blasting caused accumulative effects of damage on buildings, comfortable threshold damage limits of PPV to maintain buildings safety was given. Dynamic Stress Ratio （DSR） was adopted to study the stability of constructed tunnel on the action of blasting induced vibrations. The method to determine specific maximum charge amount per delay in Wanshishan tunnel excavation was given. It is proved that the findings in this study are very effective to control the negative effects of blasting-induced vibrations on buildings on the surface and constructed tunnel nearby.

关键词： blasting-induced vibration tunnel blasting threshold damage limits maximum charge amount per delay

Comprehensive bibliometric analysis of pharmacotherapy for bipolar disorders:Present trends and future directions

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World Journal of Psychiatry 2025年第1期15卷 153-167页

作者： Bo-Fan Chen Li Liu Fang-Zhen lin Hai-Min Zeng Hai-Qiang Huang Chun-Fang Zhang Cong-Cong Liu Xiang Chen Jie Peng Yun-Fa Wang Zhi-lin Wang Bin Chen De-Le Liu Yun Liu Zheng-Zheng Li Xin-xing Zeng The Second Affiliated Hospital Jiangxi Medical CollegeNanchang UniversityNanchang 330006Jiangxi ProvinceChina The Second Clinical Medical College Jiangxi Medical CollegeNanchang UniversityNanchang 330006Jiangxi ProvinceChina Department of Rehabilitation Medicine The Second Affiliated HospitalJiangxi Medical CollegeNanchang UniversityNanchang 330006Jiangxi ProvinceChina Jiangxi Provincial People’s Hospital The First Affiliated Hospital of Nanchang Medical CollegeNanchang 330006Jiangxi ProvinceChina Department of Psychiatry Jiangxi Mental HospitalHospital of Nanchang UniversityNanchang UniversityNanchang 330029Jiangxi ProvinceChina

BACKGROUND Bipolar disorder(BD)is a severe mental illness characterized by significant mood *** drug treatment modalities are crucial for managing *** To analyze the current status and future trends of global research on BD drug treatment over the last *** The Web of Science Core Collection database spanning from 2015 to 2024 was utilized to retrieve literature related to BD drug treatment.A total of 2624 articles were *** visualization and analysis were conducted using CiteSpace,VOSviewer,Pajek,Scimago Graphica,and R-studio bibliometrix to identify RESULTS The United States,China,and the United Kingdom have made the most significant contributions to research on BD drug treatment and formed notable research collaboration *** University of Pittsburgh,Massachusetts General Hospital,and the University of Michigan have been identified as the major research institutions in this *** Journal of Affective Disorders is the most influential journal.A keyword analysis revealed research hotspots related to clinical symptoms,drug efficacy,and genetic mechanisms.A citation analysis identified the management guidelines published by Yatham et al in 2018 as the most cited *** This study provides a detailed overview of the field of BD drug treatment,highlighting key contributors,research hotspots,and future *** study findings can be employed as a reference for future research and policymaking,which may enable further development and optimization of BD pharmacotherapy.

关键词： Bipolar disorder Drug treatment Bibliometric analysis Visualization Mental disorder

Ionosphere correction algorithm for spaceborne SAR imaging

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Journal of Systems Engineering and Electronics 2016年第5期27卷 993-1000页

作者： lin Yang Mengdao xing Guangcai Sun School of Electronic Science and Engineering National University of Defense TechnologyChangsha 410073China National Laboratory of Radar Signal Processing Xidian UniversityXi'an 710071China

For spaceborne synthetic aperture radar （SAR） imaging,the dispersive ionosphere has significant effects on the propagationof the low frequency （especially P-band） radar signal. Theionospheric effects can be a significant source of the phase error inthe radar signal, which causes a degeneration of the image qualityin spaceborne SAR imaging system. The background ionosphericeffects on spaceborne SAR through modeling and simulation areanalyzed, and the qualitative and quantitative analysis based onthe spatio-temporal variability of the ionosphere is given. A novelionosphere correction algorithm （ICA） is proposed to deal with theionospheric effects on the low frequency spaceborne SAR radarsignal. With the proposed algorithm, the degradation of the imagequality caused by the ionosphere is corrected. The simulation resultsshow the effectiveness of the proposed algorithm.

关键词： synthetic aperture radar (SAR) radar imaging highresolution ionospheric effects total electron content (TEC).

Choice of discount rate in reinforcement learning with long-delay rewards

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Journal of Systems Engineering and Electronics 2022年第2期33卷 381-392页

作者： lin Xiangyang xing Qinghua LIU Fuxian Department of Air Defense and Anti-Missile Air Force Engineering UniversityXi’an 710051China

In the world, most of the successes are results of longterm efforts. The reward of success is extremely high, but before that, a long-term investment process is required. People who are “myopic” only value short-term rewards and are unwilling to make early-stage investments, so they hardly get the ultimate success and the corresponding high rewards. Similarly, for a reinforcement learning(RL) model with long-delay rewards, the discount rate determines the strength of agent’s “farsightedness”.In order to enable the trained agent to make a chain of correct choices and succeed finally, the feasible region of the discount rate is obtained through mathematical derivation in this paper firstly. It satisfies the “farsightedness” requirement of agent. Afterwards, in order to avoid the complicated problem of solving implicit equations in the process of choosing feasible solutions,a simple method is explored and verified by theoreti cal demonstration and mathematical experiments. Then, a series of RL experiments are designed and implemented to verify the validity of theory. Finally, the model is extended from the finite process to the infinite process. The validity of the extended model is verified by theories and experiments. The whole research not only reveals the significance of the discount rate, but also provides a theoretical basis as well as a practical method for the choice of discount rate in future researches.

关键词： reinforcement learning(RL) discount rate longdelay reward Q-learning treasure-detecting model feasible solution