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Pediatric dysphagia overview:best practice recommendation study by multidisciplinary experts

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World Journal of Pediatrics 2022年第11期18卷 715-724页

作者： Ebru Umay Sibel Eyigor Esra Giray Evrim Karadag Saygi Bulent Karadag Nihal Durmus Kocaaslan Deniz Yuksel Arzu Meltem Demir Engin Tutar Canan Tikiz Eda Gurcay Zeliha Unlu Pelin Celik Ece Unlu Akyuz Guven Mengu Serkan Bengisu Sibel Alicura necati Unver Nida Yekteusaklari Cuma Uz Merve Cikili Uytuni Fatih Bagcier Elif Tarihci Mazlum Serdar Akaltun Iclal Ayranci Sucakli Damla Cankurtaran Zeynep Aykin Resa Aydin Fatma Nazli Department of Physical Medicine and Rehabilitation Ankara University of Health Sciences TurkeyAnkara Diskapi Yildirim Beyazit Training and Research HospitalIstanbulTurkey Department of Physical Medicine and Rehabilitation Ege UniversityIzmirTurkey Department of Physical Medicine and Rehabilitation Fatih Sultan Mehmet Training and Research HospitalIstanbulTurkey Department of Physical Medicine and Rehabilitation Marmara UniversityIstanbulTurkey Department of Pediatric Pulmonology Marmara UniversityIstanbulTurkey Department of Plastic Reconstructive and Aesthetic SurgeryMarmara UniversityIstanbulTurkey Department of Pediatric Neurology University of Health SciencesAnkara Dr Sami Ulus MaternityChildren's Health and Diseases Training and Research HospitalAnkaraTurkey Department of Pediatric Gastroenterology Ankara City HospitalAnkaraTurkey Department of Pediatric Gastroenterology Marmara UniversityAnkaraTurkey Department of Physical Medicine and Rehabilitation Celal Bayar UniversityManisaTurkey University of Health Sciences Turkey Gaziler Physical Medicine and Rehabilitation Training and Research HospitalAnkaraTurkey Department of Developmental Pediatric Ankara City HospitalAnkaraTurkey Department of Western Languages and Literatures Ankara Haci Bayram Veli UniversityEnglish Language and Literature DivisionAnkaraTurkey Department of Speech and Language Therapy Uskudar UniversityIstanbulTurkey Department of Otolaryngology Head and Neck SurgeryUniversity of Health SciencesAnkara Diskapi Yildirim Beyazit Training and Research HospitalAnkaraTurkey Department of Otolaryngology Head and Neck SurgeryMarmara UniversityIstanbulTurkey Department of Child and Adolescent Psychiatry Ankara UniversityAnkaraTurkey Department of Physical Medicine and Rehabilitation Istanbul Basaksehir Cam and Sakura City HospitalIstanbulTurkey Department of Physical Medicine and Rehabilitation Istanbul UniversityIstanbulTurkey Department of Physical Medicine and Rehabilitation Gaziantep UniversityGazian

Background Currently,there is no comprehensive and multidisciplinary recommendation study covering all aspects of pediatric dysphagia(PD).This study aimed to generate PD management recommendations with methods that can be used in clinical practice to fill this gap in our country and in the world,from the perspective of experienced multidisciplinary *** This recommendation paper was generated by a multidisciplinary team,using the seven-step process and a three-round modified Delphi survey via ***,ten open-ended questions were created,and then detailed recommendations including management,diagnosis,treatment,and follow-up were created with the answers from these *** recommendation item was voted on by the experts as overall consensus(strong recommendation),approaching consensus(weak recommendation)and divergent consensus(not recommended).Results In the 1st Delphi round,a questionnaire of 414 items was prepared based on the experts’responses to ten open-ended *** the 2nd Delphi round,59.2%of these items were accepted as *** the 3rd Delphi round,62.6%of 246 items were accepted for inclusion in the *** final version recommendations consisted of 154 *** This study includes comprehensive and detailed answers for every problem that could be posed in clinical practice for the management of PD,and recommendations are for all pediatric patients with both oropharyngeal and esophageal dysphagia.

关键词： Diagnosis Dysphagia Pediatric Recommendation Rehabilitation

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桥梁工程设计的综合安全风险评估法研究

华东交通大学学报 2013年第4期30卷 7-13页

作者：彭可可 F. necati. Catbas 万志勇佛山科学技术学院环境与土木建筑学院佛山528000 佛罗里达大学土木与环境工程系奥兰多佛罗里达州32816 广东省公路勘察规划设计院有限公司广州510510

以江顺大桥的斜拉桥方案初步设计阶段安全风险评估为工程背景,采用层次分析(AHP)-模糊聚类(Fuzzy Clustering)-德尔菲(Delphi method)综合风险评估法(AFD法),进行建设条件风险评估、结构方案风险评估、施工技术风险评估和工程运营管理4... 详细信息

以江顺大桥的斜拉桥方案初步设计阶段安全风险评估为工程背景,采用层次分析(AHP)-模糊聚类(Fuzzy Clustering)-德尔菲(Delphi method)综合风险评估法(AFD法),进行建设条件风险评估、结构方案风险评估、施工技术风险评估和工程运营管理4个准则层风险评估的研究。以工程实际情况及专家经验为基础确定风险源,通过层次分析确定风险准则层权重、子层权重和风险源权重。采用模糊聚类分析的方法对每个风险源的专家打分给出综合总评结果以确保专家打分结果的有效性。对专家打分数据进行分析后,结合层次分析权重结果,获得单项风险源风险水平、准则层风险水平和该项目方案整体风险水平。结果表明,该方案综合风险等级为Ⅱ级,属中度风险。本文提出的AFD法用于工程设计安全风险评估是可行的。

关键词：安全风险评估 AFD法风险概率风险损失风险等级

一种适用于媒体分配的模型：武器-目标分配方法

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国际品牌观察 2021年第13期 29-33页

作者： Eyüp ?etin Seda Tolun Esen 张方圆吴正鹏丁俊杰土耳其伊斯坦布尔大学阿夫西拉尔校区工商管理学院定量方法系中国传媒大学数据科学与智能媒体学院中国传媒大学广告学院

媒体的分配问题是媒体策划者面临的一个重要问题,其中包括在最优框架内对一场广告活动进行预算分配。本研究从军事运筹学中的武器-目标分配问题出发,建立了一种既能分配媒体又能分配预算的近似优化模型。所建立的模型与广告活动的持续... 详细信息

媒体的分配问题是媒体策划者面临的一个重要问题,其中包括在最优框架内对一场广告活动进行预算分配。本研究从军事运筹学中的武器-目标分配问题出发,建立了一种既能分配媒体又能分配预算的近似优化模型。所建立的模型与广告活动的持续时间无关。该模型是一个整数非线性规划问题。本文给出了一个假想算例,并用功能强大的电子表格工具MS Excel进行求解。MS Excel的求解器也被用来解决非线性规划NP-完全类型的问题。这项研究是将军事运筹学模型应用到商业界中的一个很好的例子。

关键词：媒体建模广告宣传预算分配整数非线性规划电子表格建模军事行动研究

Noncontrast-enhanced MRI-based Noninvasive Score for Portal Hypertension(CHESS1802):An International Multicenter Study

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Journal of Clinical and Translational Hepatology 2021年第6期9卷 818-827页

作者： Yanna Liu Tianyu Tang necatiÖrmeci Yifei Huang Jitao Wang Xiaoguo Li Zhiwei Li Weimin An Dengxiang Liu Chunqing Zhang Changchun Liu Jinqiang Liu Chuan Liu Guangchuan Wang Cristina Mosconi Alberta Cappelli Antonio Bruno Seray Akçalar EmrecanÇelebioğlu EvrenÜstüner Sadık Bilgiç Zeynep Ellik ÖzgünÖmer Asiller Lei Li Haijun Zhang Ning Kang Dan Xu Ruiling He Yan Wang Yang Bu Ye Gu Shenghong Ju Rita Golfieri Xiaolong Qi CHESS Center Institute of Portal HypertensionThe First Hospital of Lanzhou UniversityLanzhouGansuChina CHESS Center The Sixth People’s Hospital of ShenyangShenyangLiaoningChina Department of Infectious Disease Nanfang HospitalSouthern Medical UniversityGuangzhouGuangdongChina Department of Microbiology and Infec-tious Disease Center School of Basic Medical SciencesPeking University Health Science CenterBeijingChina Depart-ment of Radiology Zhongda HospitalMedical School of Southeast UniversityNanjingJiangsuChina Istanbul Health and Technology University Zytinburnu/İstanbulTurkey CHESS Working Party Xingtai People’s HospitalXingtaiHebeiChina Department of Hepatobiliary Surgery The Third People’s Hospital of ShenzhenShenzhenGuangdongChina Department of Radiology Fifth Medical Center of PLA General HospitalBeijingChina Department of Gastroenterol-ogy Shandong Provincial Hospital Affiliated to Shandong UniversityJinanShandongChina Department of Radiology IRCCS Azienda Ospedaliero-Universitaria di BolognaUniversity of BolognaItaly Department of Radiology Ankara University School of MedicineAnkaraTurkey Department of Gastroenterology Ankara University School of MedicineAnkaraTurkey Department of Hepatobiliary Surgery People’s Hospital of Ningxia Hui Autonomous RegionYinchuanNingxiaChina

Background and Aims:This study aimed to determine the performance of the non-invasive score using noncontrastenhanced MRI(CHESS-DIS score)for detecting portal hy-pertension in ***:In this international multicenter,diagnostic study(***,NCT03766880),patients with cirrhosis who had hepatic venous pressure gradient(HVPG)measurement and noncontrast-enhanced MRI were prospectively recruited from four university hospitals in China(n=4)and Turkey(n=1)between December 2018 and April 2019.A cohort of patients was retrospectively recruited from a university hospital in Italy between March 2015 and November *** segmentation of the liver on fat-suppressed T1-weighted MRI maps,CHESS-DIS score was calculated automatically by an in-house developed code based on the quantification of liver surface ***:A total of 149 patients were included,of which 124 were from four Chinese hospitals(training cohort)and 25 were from two international hospitals(validation cohort).A positive correlation between CHESS-DIS score and HVPG was found with the correlation coefficients of 0.36(p<0.0001)and 0.55(p<0.01)for the training and validation cohorts,*** area under the receiver operating characteristic curve of CHESS-DIS score in detection of clinically significant portal hypertension(CSPH)was 0.81 and 0.9 in the training and validation cohorts,*** intra-class correlation coefficients for assessing the inter-and intra-observer agreement were 0.846 and 0.841,***:A non-invasive score using noncontrast-enhanced MRI was developed and proved to be significantly correlated with invasive ***,this score could be used to detect CSPH in patients with cirrhosis.

关键词： Liver cirrhosis Advanced chronic liver disease Hepatic venous pressure gradient Liver surface nodularity Imaging

Impact of adjuvant treatment modalities on survival outcomes in curatively resected pancreatic and periampullary adenocarcinoma

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Chinese Journal of Cancer Research 2015年第4期27卷 408-416页

作者： Nedim Turan Mustafa Benekli Olcun Umit Unal ?lkay Tugba Unek Didem Tastekin Faysal Dane Efnan Alg?n Sukran Ulger Tulay Eren Turkan Ozturk Topcu Esma Turkmen Nalan Akgül Babacan Gulnihal Tufan Zuhat Urakci Basak Oven Ustaalioglu Ozlem Sonmez Uysal Ozlem Balvan Ercelep Burcu Yapar Taskoylu Asude Aksoy Mustafa Canhoroz Umut Demirci Erkan Dogan Veli Berk Ozan Balakan Ahmet ?iyar Ekinci Mukremin Uysal ?brahim Petekkaya Sel?uk Cemil Ozturk ?nder Tonyal? Bülent ?etin Mehmet Naci Aldemir Kaan Helvac? Nuriye Ozdemir ?lhan Oztop Ugur Coskun Aytug Uner Ahmet Ozet Suleyman Buyukberber Department of Medical Oncology Faculty of Medicine Cumhuriyet University Department of Medical Oncology Faculty of Medicine Gazi University Department of Medical Oncology Faculty of Medicine Dokuz Eylul University Department of Medical Oncology Faculty of Medicine Necmettin Erbakan University Department of Medical Oncology Faculty of Medicine Marmara University Department of Radiation Oncology Faculty of Medicine Gazi University Department of Medical Oncology Numune Education and Research Hospital Department of Medical Oncology Faculty of Medicine Karadeniz Technical University Department of Medical Oncology Faculty of Medicine Trakya University Department of Medical Oncology Rize Education and Research Hospital Department of Medical Oncology Faculty of Medicine Dicle University Department of Medical Oncology Dr.Lutfi Kirdar Kartal Education and Research Hospital Department of Medical Oncology Sakarya Education and Research Hospital Department of Medical Oncology Faculty of Medicine Pamukkale University Department of Medical Oncology Faculty of Medicine Inonu University Department of Medical Oncology Faculty of Medicine Firat University Department of Medical Oncology Dr.Abdurrahman Yurtaslan Education and Research Hospital Department of Medical Oncology Faculty of Medicine Yuzuncu Yil University Department of Medical Oncology Faculty of Medicine Erciyes University Department of Medical Oncology Faculty of Medicine Sutcu Imam University Department of Medical Oncology Diyarbakir Education and Research Hospital Department of Medical Oncology Faculty of Medicine Kocatepe University Department of Medical Oncology Dr.Ersin Arslan State Hospital Department of Medical Oncology Education and Research Hospital Ad?yaman University Department of Medical Oncology Faculty of Medicine Mustafa Kemal University Department of Medical Oncology Faculty of Medicine Ataturk University

Background： We examined the impact of adjuvant modalities on resected pancreatic and periampullary adenocarcinoma（PAC）.Methods： A total of 563 patients who were curatively resected for PAC were retrospectively analyzed between 2003 and ***： Of 563 patients, 472 received adjuvant chemotherapy（CT） alone, chemoradiotherapy（CRT） alone, and chemoradiotherapy plus chemotherapy（CRT-CT） were analyzed. Of the 472 patients, 231 were given CRT-CT, 26 were given CRT, and 215 were given CT. The median recurrence-free survival（RFS） and overall survival（OS） were 12 and 19 months, respectively. When CT and CRT-CT groups were compared, there was no significant difference with respect to both RFS and OS, and also there was no difference in RFS and OS among CRT-CT, CT and CRT groups. To further investigate the impact of radiation on subgroups, patients were stratified according to lymph node status and resection margins. In node-positive patients, both RFS and OS were significantly longer in CRT-CT than CT. In contrast, there was no significant differencebetween groups when patients with node-negative disease or patients with or without positive surgical margins were ***： Addition of radiation to CT has a survival benefit in patients with node-positive disease following pancreatic resection.

关键词： Pancreatic adenocarcinoma adjuvant chemotherapy(adjuvant CT) adjuvant radiotherapy

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银屑病患者的跟腱超声评估

世界核心医学期刊文摘（皮肤病学分册） 2006年第2期2卷 58-58页

作者： zckar L. etin A. Inánici F. 李政霄 Horasan Sokak 17/6 Gaziosmanpasa 06700 Ankara Turkey

Background: Psoriasis is a common dermatological disease with erythematous plaques where articular and extra articular findings (tenosynovitis and enthesitis) may well accompany. The aim of this current study was to evaluate the Achilles’ tendon of psoriasis patients with ultrasonography. Methods: The study comprised 30 psoriasis patients and 20 healthy controls. Ankle ultrasonography was performed with posterior approach, the joint in neutral or in a little dorsiflexed position. The statistical analysis was carried out with a Student’ s t- test and Spearman correlation tests. Results: The mean values of Achilles’ tendon thickness of two groups were compared: the psoriatic group was found to have thicker tendon measurements (P = 0.00). The tendons of the patients with radiologically proven enthesopathy were found to be even thicker (P=0.001). Conclusions: We encourage the use of diagnostic ultrasonography for evaluation of enthesopathy manifestations in psoriasis patients as an adjunct to conventional methods owing to its convenience and promising results.

关键词：银屑病起止点炎超声检查起止点病背屈位中间位斑块性影像学 Student 统计分析

Tolerance and acceptance of hepatic venous pressure gradient measurement in cirrhosis(CHESS1904):An international multicenter study

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Portal Hypertension & Cirrhosis 2022年第1期1卷 7-14页

作者： Jun‐Hui Sun He Zhao Haijun Zhang Lei Li necatiÖrmeci Zi‐Niu Yu Xun Li Shuangxi Li Xujun Yang Huaping Wei Xiaoliang Zhu Zhengcong Zhang Yajin Wang Zhongwei Zhao Jianting Mao Qiaohong Wu Xiaole Sun Huiling Xiang Kefeng Jia Chao Yang Wei Wu Xiuqing Lin Haixin Yao Changzeng Zuo Jitao Wang Bo Zhang Chunqing Zhang Xiaoling Wu Guangchuan Wang Shengjuan Yao Ruihang Wang Li Zhou Hui Huan Qingli Tu Xue Pu Feng Zhang Qin Yin Linpeng Zhang Ying Guo Jian Wang Kohei Kotani Sawako Uchida‐Kobayashi Norifumi Kawada He Zhu Li Li Wei Wang Guo Zhang Lei Yu Xudong Cui Qingliang Zhu Hailong Zhang Xiaoli Hu Rafael OXimenes Adriano Gonçalves de Araújo Giulliano Gardenghi Yubao Zheng Zebin Wu Mingsheng Huang Xiaoyong Chen Jun Wu Feng Xie Yang Bo Shengjuan Hu Linke Ma Xiao Li Xiaolong Qi Hepatobiliary and Pancreatic Interventional Treatment Center Division of Hepatobiliary and Pancreatic SurgeryThe First Affiliated HospitalZhejiang University School of MedicineZhejiang Clinical Research Center of Hepatobiliary and Pancreatic DiseasesZhejiang Provincial Research Center for Diagnosis and Treatment of Heapatobiliary DiseasesZhejiang University Cancer CenterHangzhouZhejiangChina Department of Interventional Therapy National Cancer Center/National Clinical Research Center/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina Institute of Portal Hypertension Department of General SurgeryThe First Hospital of Lanzhou UniversityLanzhouGansuChina Department of Anesthesiology and Operating Theater The First Hospital of Lanzhou UniversityLanzhouGansuChina Interventional Radiology Department The First Hospital of Lanzhou UniversityLanzhouGansuChina Department of Gastroenterology Ankara University School of MedicineAnkaraTurkey Department of Internal Medicine Istanbul Health and Technology University Medical SchoolIstanbulTurkey Department of General Surgery Key Laboratory of Biotherapy and Regenerative Medicine of Gansu ProvinceThe First Hospital of Lanzhou UniversityLanzhouGansuChina Nursing Department The First Hospital of Lanzhou UniversityLanzhouGansuChina Department of General Surgery Donggang BranchFirst Hospital of Lanzhou UniversityLanzhouGansuChina The Diagnosis and Treatment Center of Endoscopy and Interventional Radiology Department of General SurgeryDonggang BranchFirst Hospital of Lanzhou UniversityLanzhouGansuChina Department of Interventional Radiology Lishui Central HospitalLishuiZhejiangChina Department of Hepatology and Gastroenterology of The Third Central Hospital of Tianjin TianjinChina Department of Radiology of The Third Central Hospital of Tianjin TianjinChina Department of Gastroenterology The First Affiliated Hospital of Wenzhou Medical UniversityWenzhouZhejiangChina Department of Hepatobiliar

Aim:To determine the tolerance and acceptance of hepatic venous pressure gradient(HVPG)measurements in patients with liver ***:This prospective international multicenter study included 271 patients with cirrhosis who were scheduled to undergo HVPG measurement between October 2019 and June *** related to the tolerance and acceptance of HVPG measurements were collected using descriptive ***:HVPG measurements were technically successful in all 271 patients,with 141(52.0%)undergoing HVPG measurement *** complication rate was 0.4%.Postoperative pain was significantly lower than preoperative expected pain(p<0.001)and intraoperative pain(p<0.001),and intraoperative pain was also significantly lower than preoperative expected pain(p=0.036).No,mild,moderate,severe,and intolerable discomfort scores were reported by 36.9%,44.6%,11.1%,6.3%,and 0.4%of these patients,respectively,during HVPG measurement and by 54.6%32.5%,11.4%,1.5%,and 0%,respectively,after HVPG *** these patients,39.5%had little understanding and 10%had no understanding of the value of HVPG measurement,with 35.1%and 4.1%regarding HVPG measurements as being of little or no help,*** patients reported that they would definitely(15.5%),probably(46.9%),or possibly(29.9%)choose to undergo additional HVPG measurements again,and 62.7%regarded the cost of the procedure as ***:HVPG measurement was safe and well‐tolerated in patients with cirrhosis,but patient education and communication are warranted to improve the acceptance of this procedure.

关键词： design hypertension multicenter study portal pressure prospective study questionnaire wedge