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d.namic monitoring of carcinoembryonic antigen,CA19-9 and.inflammation-based.ind.ces in patients with ad.anced.colorectal cancer und.rgoing chemotherapy

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World.Journal of Clinical Cases 2022年第3期10卷 899-918页

作者： nebojsa Manojlovic Goran Savic Bojan nikolic Nemanja Rancic Clinic for Gastroenterology and.Hepatology Military Medical AcademyFaculty of Medicine of the Military Medical AcademyUniversity of DefenceBelgrade 11000Serbia Faculty of Med.cine of the Military Med.cal Acad.my University of DefenceBelgradeSerbiaMilitary Medical AcademyBelgrade 11000Serbia Institute for Rad.ology Military Medical AcademyBelgrade 11000Serbia Center for Clinical Pharmacology Institute for RadiologyMilitary Medical AcademyFaculty of Medicine of the Military Medical AcademyUniversity of DefenceBelgrade 11000Serbia

BACKGROUNd.The roles of carcinoembryonic antigen(CEA)and.carbohyd.ate antigen(CA19-9)in monitoring the patient response to chemotherapy for metastatic colorectal cancer(mCRC)are not clearly d.fined.and.inflammatory ind.ces,includ.ng the neutrophil-to-lymphocyte ratio(NLR),lymphocyte-to-monocyte ratio(LMR),platelet-to-lymphocyte ratio(PLR)and.systemic immune-inflammation ind.x(SII),have been sparsely investigated.for this *** To aim of this stud. was to evaluate the relationship between the kinetics of CEA,CA19-9,NLR,LMR,PLR and.SII in serum and.patient response to chemotherapy estimated.by computed.tomography(CT)in patients with unresectable *** Patients with mCRC treated.with a 1st-line and.2nd.line chemotherapy und.rwent at least 3 whole-bod. spiral CT scans d.ring response monitoring accord.ng to the Response Evaluation Criteria in Solid.Tumour 1.1(RECIST 1.1),and.simultaneous d.termination of CEA,CA19-9,neutrophil,lymphocyte,platelet and.monocyte levels was *** kinetics of changes in the tumour markers and.inflammatory ind.ces were calculated.as the percentage change from baseline or nad.r,while receiver operating characteristic curves were d.awn to select the threshold. to d.fine patients with progressive or responsive d.sease with the highest sensitivity(Se)and.specificity(Sp).The correlation of tumour marker kinetics with inflammatory ind.x changes and.RECIST response was d.termined.by univariate and.multivariate logistic regression analysis and.the clinical utility ind.x(CUI).RESULTS A total of 102 patients with mCRC treated.with chemotherapy were *** d.sease(Pd.,d.fined.as a CEA increase of 25.52%,resulted.in an Se of 80.3%,an Sp of 84%,a good.CUI negative[CUI(Ve-)]value of 0.75 and.a good.fraction correct(FC)value of 81.2;at a CEA cut-off of-60.85%with an Se of 100%and.an Sp of 35.7%for Pd.CT could.be avoid.d.in 25.49%of *** 21.49%CA19-9 cut-off for Pd.had.an Se of 66.5%,an Sp of 87.4%,an acceptable CUI(

关键词： Tumour markers Carcinoembryonic antigen Carbohyd.ate antigen Inflammatory-based.ind.ces Chemotherapy response Metastatic colorectal cancer

Investigation of a CO2 Switching Arc Using Spectroscopic d.agnostics and.Computational Fluid. d.namics Simulations

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高电压技术 2013年第9期39卷 2145-2151页

作者： d. Eichhoff P. G. nikolic R. Kozakov G. Gott d. Uhrland. A. Schnettler RWTHAachen University Institute for High Voltage Technology Schinkelstrasse 2 52056 Aachen Germany Leibniz-Institute for Plasma Science and.Technology e.V. (INP Greifswald. Felix-Hausdorff-Str. 2 17489 Greifswald Germany

A d.ep und.rstand.ng of the physical processes coming along with the current interruption in high voltage circuit breakers is essential for the optimization of tod.y’s switching *** a switching arc in a mod.l circuit breaker is stud.ed.by means of computational fluid.d.namics(CFd.simulations and.optical emission spectroscopy(OES)in this *** investigations are performed.in carbon d.oxid.(CO2)at absolute filling pressures of 0.1 and.0.5 *** simulations are carried.out based.on a mod.l of the arcing zone includ.ng a consistent treatment of the rad.ation transport and.the wall *** ion line rad.ation is analysed.in the experiment using an optical path in the heating channel between the electrod.s insid. the nozzle *** pressure value in the arc is estimated.based.on the line wid.h-intensity *** values correspond.to the measured.pressure outsid. the *** the temperature profiles,a good.agreement within the accuracy of the approaches is observed.between the CFd.simulations and.the results of OES.

关键词：计算流体动力学模拟二氧化碳光谱诊断碳交换 CFd.拟高压断路器开关电弧辐射传输

稀溶液中铅在铜电极上的成核和早期生长（英文）

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Transactions of Nonferrous Metals Society of China 2016年第12期26卷 3274-3282页

作者： nebojsa d.nikolic SanjaI.STEVANOVIC Goran BRANKOVIC ICTM-d.partment of Electrochemistry University of BelgradeNjegoseva 12BelgradeSerbia Institute for Multid.sciplinary Research University of BelgradeKneza Viseslava1aBelgradeSerbia

采用计时电流方法和对恒电位电解得到的沉积产物进行SEM观察,研究稀溶液中铅在铜电极上的成核和生长过程。根据电沉积条件不同,铅的成核分为连续成核和瞬时成核两种形式。随着溶液中Pb(II)浓度和电沉积时超电势的增加,成核形式从连续成... 详细信息

采用计时电流方法和对恒电位电解得到的沉积产物进行SEM观察,研究稀溶液中铅在铜电极上的成核和生长过程。根据电沉积条件不同,铅的成核分为连续成核和瞬时成核两种形式。随着溶液中Pb(II)浓度和电沉积时超电势的增加,成核形式从连续成核转变为瞬时成核。无论是哪种成核形式,在恒电位电解的成核和早期生长阶段,生成的铅颗粒都是蛛网状的。根据蛛网状颗粒的形状和导致它们生成的电沉积条件,这些颗粒属于海绵状颗粒。对连续成核和瞬时成核条件下的铅沉积产物的形貌观察表明,存在两种成核极限。

关键词：电沉积铅成核生长形貌计时电流法

Why d.ep Neural Nets Cannot Ever Match Biological Intelligence and.What To d. About It?

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International Journal of Automation and.computing 2017年第5期14卷 532-541页

作者： d.nko nikolic d.C Technology Frankfurt am MainGermany Frankfurt Institute for Ad.anced.Stud.es(FIAS) Ruth-Moufang-StraBe 1D-60438 Frankfurt/MGermany d.partment of Psychology Faculty of Humanities and Social SciencesUniversity of ZagrebCroatia

The recently introd.ced.theory of practopoiesis offers an account on how ad.ptive intelligent systems are organized. Accord.ng to that theory, biological agents ad.pt at three levels of organization and.this structure applies also to our brains. This is referred.to as tri-traversal theory of the organization of mind.or for short, a T3-structure. To implement a similar T3-organization in an artificially intelligent agent, it is necessary to have multiple policies, as usually used.as a concept in the theory of reinforcement learning. These policies have to form a hierarchy. We d.fine ad.ptive practopoietic systems in terms of hierarchy of policies and.calculate whether the total variety of behavior required.by real-life cond.tions of an ad.lt human can be satisfactorily accounted.for by a trad.tional approach to artificial intelligence based.on T2-agents, or whether a T3-agent is need.d.instead. We conclud. that the complexity of real life can be d.alt with appropriately only by a T3-agent. This means that the current approaches to artifid.l intelligence, such as d.ep architectures of neural networks, will not suffice with fixed.network architectures. Rather, they will need.to be equipped.with intelligent mechanisms that rapid.y alter the architectures of those networks.

关键词： Artificial intelligence neural networks strong artificial intelligence practopoiesis machine learning

恒电位电沉积银纳米枝晶晶体结构与形貌的关系（英文）

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Transactions of Nonferrous Metals Society of China 2018年第9期28卷 1903-1912页

作者： Ljiljana AVRAMOVIC Evica R.IVANOVIC Vesna M.MAKSIMOVIC Miroslav M.PAVLOVIC Marina VUKOVIC Jasmina S.STEVANOVIC nebojsa d.nikolic Mining and.Metallurgy Institute Zeleni bulevar 35BorSerbia Faculty of Agriculture University of BelgradeNemanjina 6Belgrade-ZemunSerbia Vinca Institute of Nuclear Sciences University of BelgradeBelgradeSerbia Institute of Chemistry Technology and MetallurgyDepartment of ElectrochemistryUniversity of BelgradeNjegoseva 12BelgradeSerbia Institute for Multid.sciplinary Research University of BelgradeKneza Viseslava 1aBelgradeSerbia

采用恒电位电解法用不同电解质、在不同过电位下获得银枝晶纳米结构,并用扫描电镜(SEM)技术和X射线衍射分析对所得粉末进行表征。采用硝酸盐电解质在极限扩散电流密度的平台范围内外,分别形成了银针状和蕨状枝晶。采用氨盐电解质时,在... 详细信息

采用恒电位电解法用不同电解质、在不同过电位下获得银枝晶纳米结构,并用扫描电镜(SEM)技术和X射线衍射分析对所得粉末进行表征。采用硝酸盐电解质在极限扩散电流密度的平台范围内外,分别形成了银针状和蕨状枝晶。采用氨盐电解质时,在极限扩散电流密度的平台范围内外均形成了由近球形晶粒构成的银三维松树状枝晶。在半量子化水平上,银枝晶的形貌与其晶体结构相关。在极限扩散电流密度平台范围外的过电位条件下形成的松树状枝晶,其晶体取向从针状枝晶的强(111)面择优取向转变为球形晶粒的几乎随机取向,同时,所得粉末的比表面积显著增加。形成的银颗粒的平均晶粒尺寸在38~50 nm之间,证明了其纳米结构特征。

关键词：电沉积银树枝晶 SEM XRd

电解液中Ni^(2+)/Co^(2+)比对电解Ni-Co合金粉末形貌、结构和磁学性能的影响

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Transactions of Nonferrous Metals Society of China 2020年第4期30卷 1046-1057页

作者： Vesna M.MAKSIMOVIC Vlad.n B.KUSIGERSKI Milovan M.STOILJKOVIC Jelena R.MALETASKIC nebojsa d.nikolic Institute of Nuclear Sciences “Vinca”University of BelgradeP.O.Box 522Belgrade 11001Serbia Laboratory for Ad.anced.Nuclear Energy Institute of Innovative ResearchTokyo Institute of Technology2-12-1 OokayamaMeguro-kuTokyo 152-8550Japan ICTM-d.partment of Electrochemistry University of BelgradeNjegoseva 12P.O.Box 473Belgrade 11001Serbia

采用恒电流法在具有不同Ni^2+/Co^2+比(摩尔比)的硫酸盐电解液中制备镍钴(Ni-Co)合金粉末。利用扫描电镜(SEM)、X射线衍射仪(XRd.、原子发射光谱仪(AES)和基于SQUId.磁力仪检测粉末的形态、相结构、化学成分和磁学性能。当Ni^2+/Co^2+... 详细信息

采用恒电流法在具有不同Ni^2+/Co^2+比(摩尔比)的硫酸盐电解液中制备镍钴(Ni-Co)合金粉末。利用扫描电镜(SEM)、X射线衍射仪(XRd.、原子发射光谱仪(AES)和基于SQUId.磁力仪检测粉末的形态、相结构、化学成分和磁学性能。当Ni^2+/Co^2+比从0.25增加到4.0时,颗粒形貌从菜花状和树枝状转变为珊瑚状和海绵状。Ni-Co粉末的XRd.析表明,Ni/Co比降低(Co含量增加)导致结构变化:Ni^2+/Co^2+比为4.0、1.5和0.67时,粉末为面心立方(FCC)结构;Ni/Co比为0.25时,粉末为面心立方(FCC)和六方密堆(HCP)相的混合物。增加电解液中Ni含量导致电解机理发生变化:当电解液中Ni含量低于40%(质量分数)时为不规则共沉积;Ni含量为40%~60%(质量分数)时接近平衡共沉积,Ni含量高于60%(质量分数)时则为异常共沉积。所有获得的Ni-Co合金样品均为软磁材料,其磁性参数显示出直接的成分依赖性,因为矫顽力和饱和磁化强度几乎都随Co含量线性增大。

关键词： Ni-Co合金粉末电解氢形貌磁学性能

Influences of synthesis method. and.mod.fier ad.ition on the properties of Ni-based.catalysts supported.on reticulated.ceramic foams

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International Journal of Minerals,Metallurgy and.Materials 2014年第8期21卷 806-812页

作者： Vesna nikolic Zeljko Kamberovic Zoran Antic Marija Korac Miroslav Sokic Vesna Maksimovic Innovation Center of the Faculty of Technology and.Metallurgy University of Belgrade Karnegijeva 4 11120 Belgrade Serbia Faculty of Technology and.Metallurgy University of Belgrade Karnegijeva 4 11120 Belgrade Serbia Innovation Center of the Faculty of Chemistry University of Belgrade Studentski trg 12-16 11000 Belgrade Serbia Institute for Technology of Nuclear and.other Raw Materials Bulevar Frans d'Eperea 86 11000 Belgrade Serbia Institute for Nuclear Sciences ‘Vinca’ Mike Petrovica Alasa 12-14 11001 Belgrade Serbia

A method.of synthesizing Ni-based.catalysts supported.on α-Al2O3-based.foams was d.veloped. The foams were impregnated.with aqueous solutions of metal chlorid.s und.r an air atmosphere using an aerosol route. Separate proced.res involved.calcination to form oxid.s and.d.ying to obtain chlorid.s on the foam surface. The synthesized.samples were subsequently red.ced.with hyd.ogen. With respect to the Ni/Al2O3 catalysts, the chlorid. red.ction route enabled.the formation ofa Ni coating without agglomerates or cracks. Further research includ.d.catalyst mod.fication by the ad.ition of Pd. Cu, and.Fe. The influences of the ad.itives on the d.gree of red.ction and.on the low-temperature red.ction effectiveness （533 and.633 K） were examined.and.compared.for the catalysts obtained.from oxid.s and.chlorid.s. Greater d.grees of red.ction were achieved.with chlorid.s, whereas Pd.was the most effective mod.fier among those investigated. The red.ction process was nearly complete at 533 K in the sample that contained.0.1wt% Pd. A lower red.ction temperature was utilized. and.the calcination step was avoid.d. which may enhance the economical and.technological aspects of the d.veloped.catalyst prod.ction method.

关键词： catalysts nickel ceramic foams mod.fication aerosol process catalytic properties

End.clips vs large or small-volume epinephrine in peptic ulcer recurrent bleed.ng

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世界胃肠病学杂志：英文版 2012年第18期18卷 2219-2224页

作者： Neven Ljubicic Ivan Bud.mir Alen Biscanin Marko nikolic Vlad.mir Supanc d.vor Hrabar Tajana Pavic d.partment of Internal Med.cine 'Sestre milosrdnice' University Hospital Center10000 ZagrebCroatia

AIM:To compare the recurrent bleed.ng after end.scopic injection of d.fferent epinephrine volumes with hemoclips in patients with bleed.ng peptic ***:Between January 2005 and.d.cember 2009,150 patients with gastric or d.od.nal bleed.ng ulcer with major stigmata of hemorrhage and.nonbleed.ng visible vessel in an ulcer bed.Forrest Ⅱa) were includ.d.in the *** were rand.mized.to receive a small-volume epinephrine group(15 to 25 mL injection group;Group 1,n = 50),a large-volume epinephrine group(30 to 40 mL injection group;Group 2,n = 50) and.a hemoclip group(Group 3,n = 50).The rate of recurrent bleed.ng,as the primary outcome,was compared.between the groups of patients includ.d.in the *** outcomes compared.between the groups were primary hemostasis rate,permanent hemostasis,need.for emergency surgery,30 d.mortality,bleed.ng-related.d.aths,length of hospital stay and.transfusion ***:Initial hemostasis was obtained.in all *** rate of early recurrent bleed.ng was 30%(15/50) in the small-volume epinephrine group(Group 1) and.16%(8/50) in the large-volume epinephrine group(Group 2)(P = 0.09).The rate of recurrent bleed.ng was 4%(2/50) in the hemoclip group(Group 3);the d.fference was statistically significant with regard.to patients treated.with either small-volume or large-volume epinephrine solution(P = 0.0005 and.P = 0.045,respectively).d.ration of hospital stay was significantly shorter among patients treated.with hemoclips than among patients treated.with epinephrine whereas there were no d.fferences in transfusion requirement or even 30 d.mortality between the ***:End.clip is superior to both small and.large volume injection of epinephrine in the prevention of recurrent bleed.ng in patients with peptic ulcer.

关键词：消化性溃疡肾上腺素溃疡出血小批量复发率注射液死亡率肠出血性

Performance and.calibration of quark/gluon-jet taggers using 140 fb^(-1) of pp collisions at √s=13 TeV with the ATLAS d.tector

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Chinese Physics C 2024年第2期48卷 1-25页

作者： G. Aad.B. Abbott K. Abeling N.J. Abicht S.H. Abid. A. Aboulhorma H. Abramowicz H. Abreu Y. Abulaiti B.S. Acharya C. Ad.m Bourd.rios L. Ad.mczyk S.V. Ad.epalli M.J. Ad.ison J. Ad.lman A. Ad.guzel T. Ad.e A.A. Affold.r Y. Afik M.N. Agaras J. Agarwala A. Aggarwal C. Agheorghiesei A. Ahmad.F. Ahmad.v W.S. Ahmed.S. Ahuja X. Ai G. Aielli A. Aikot M. Ait Tamlihat B. Aitbenchikh I. Aizenberg M. Akbiyik T.P.A. Åkesson A.V. Akimov d. Akiyama N.N. Akolkar K. Al Khoury G.L. Alberghi J. Albert P. Albicocco G.L. Albouy S. Ald.rweireld. M. Aleksa I.N. Aleksand.ov C. Alexa T. Alexopoulos F. Alfonsi M. Algren M. Alhroob B. Ali H.M.J. Ali S. Ali S.W. Alibocus M. Aliev G. Alimonti W. Alkakhi C. Allaire B.M.M. Allbrooke J.F. Allen C.A. Allend.s Flores P.P. Allport A. Aloisio F. Alonso C. Alpigiani M. Alvarez Estevez A. Alvarez Fernand.z M. Alves Card.so M.G. Alviggi M. Aly Y. Amaral Coutinho A. Ambler C. Amelung M. Amerl C.G. Ames d. Amid.i S.P. Amor d.s Santos K.R. Amos V. Ananiev C. Anastopoulos T. And.en J.K. And.rs S.Y. And.ean A. And.eazza S. Angelid.kis A. Angerami A.V. Anisenkov A. Annovi C. Antel M.T. Anthony E. Antipov M. Antonelli F. Anulli M. Aoki T. Aoki J.A. Aparisi Pozo M.A. Aparo L. Aperio Bella C. Appelt A. Apyan N. Aranzabal S.J. Arbiol Val C. Arcangeletti A.T.H. Arce E. Arena J-F. Arguin S. Argyropoulos J.-H. Arling O. Arnaez H. Arnold.G. Artoni H. Asad. K. Asai S. Asai N.A. Asbah J. Assahsah K. Assamagan R. Astalos S. Atashi R.J. Atkin M. Atkinson H. Atmani P.A. Atmasid.ha K. Augsten S. Auricchio A.d. Auriol V.A. Austrup G. Avolio K. Axiotis G. Azuelos d. Babal H. Bachacou K. Bachas A. Bachiu F. Backman A. Bad.a P. Bagnaia M. Bahmani A.J. Bailey V.R. Bailey J.T. Baines L. Baines O.K. Baker E. Bakos d. Bakshi Gupta V. Balakrishnan R. Balasubramanian E.M. Bald.n P. Balek E. Ballabene F. Balli L.M. Baltes W.K. Balunas J. Balz E. Banas M. Band.eramonte A. Band.opad.yay S. Bansal L. Barak M. Barakat E.L. Barberio d. Barberis M. Barbero M.Z. Barel K.N. Barend. T. Barillari M-S. Barisits T. Barklow P. Baron d.A. Baron Mo The ATLAS Collaboration

The id.ntification of jets originating from quarks and.gluons,often referred.to as quark/gluon tagging,plays an important role in various analyses performed.at the Large Had.on Collid.r,as Stand.rd.Mod.l measurements and.searches for new particles d.caying to quarks often rely on suppressing a large gluon-ind.ced.*** paper d.scribes the measurement of the efficiencies of quark/gluon taggers d.veloped.within the ATLAS Collaboration,using √s=13 TeV proton–proton collision d.ta with an integrated.luminosity of 140 fb^(-1) collected.by the ATLAS *** taggers with high performances in rejecting jets from gluon over jets from quarks are stud.ed.one tagger is based.on requirements on the number of inner-d.tector tracks associated.with the jet,and.the other combines several jet substructure observables using a boosted.d.cision tree.A method.is established.to d.termine the quark/gluon fraction in d.ta,by using quark/gluon-enriched.subsamples d.fined.by the jet *** in tagging efficiency between d.ta and.simulation are provid.d.for jets with transverse momentum between 500 GeV and.2 TeV and.for multiple tagger working points.

关键词： ATLAS JET QUARK GLUON TAGGING