检索结果-南通市图书馆

There is more to the knee joint than just the quadriceps:A systematic review with meta-analysis and evidence gap map of hamstring strength,flexibility,and morphology in individuals with gradual-onset knee disorders

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Sport and Health Science 2024年第4期13卷 521-536页

作者： Helder S.Lopes Marina C.Waiteman Liliam b.Priore neal R.Glaviano David M.bazett-Jones Ronaldo V.briani Fabio M.Azevedo School of Science and Technology Physical Therapy DepartmentSao Paulo State University(UNESP)Presidente Prudente 19060-900Brazil Department of Kinesiology College of AgricultureHealth and Natural ResourcesUniversity of ConnecticutStorrsCT 06269USA School of Exercise and Rehabilitation Sciences College of Health and Human ServicesUniversity of ToledoToledoOH 43606USA

background:Impairments in hamstring strength,flexibility,and morphology have been associated with altered knee biomechanics,pain,and *** the presence of these impairments in individuals with gradual-onset knee disorders is important and may indicate targets for assessment and *** systematic review aimed to synthesize the literature to determine the presence of impairments in hamstring strength,flexibility,and morphology in individuals with gradual-onset knee ***:Five databases(MEDLINE,Embase,CINAHL,SPORTDiscus,and Web of Science)were searched from inception to September *** studies comparing hamstring outcomes(e.g.,strength,flexibility,and/or morphology)between individuals with gradual-onset knee disorders and their unaffected limbs or pain-free controls were ***-analyses for each knee disorder were ***-level certainty was assessed using the Grading of Recommendations Assessment,Development,and Evaluation,and evidence gap maps were ***:Seventy-nine studies across 4 different gradual-onset knee disorders(i.e.,knee osteoarthritis(OA),patellofemoral pain(PFP),chondromalacia patellae,and patellar tendinopathy)were *** with knee OA presented with reduced hamstring strength compared to pain-free controls during isometric(standard mean difference(SMD)=-0.76,95%confidence interval(95%CI):-1.32 to-0.21)and concentric contractions(SMD=-0.97,95%CI:-1.49 to-0.45).Individuals with PFP presented with reduced hamstring strength compared to painfree controls during isometric(SMD=-0.48,95%CI:-0.82 to-0.14),concentric(SMD=-1.07,95%CI:-2.08 to-0.06),and eccentric contractions(SMD=-0.59,95%CI:-0.97 to-0.21).No differences were observed in individuals with patellar *** with PFP presented with reduced hamstring flexibility when compared to pain-free controls(SMD=-0.76,95%CI:-1.15 to-0.36).Evidence gap maps identified insufficient evidence for chondromalacia patel

关键词： Chondromalacia patellae Knee flexors Knee osteoarthritis Patellar tendinopathy Patellofemoral pain

Developmental transcription factors in age-related CNS disease: a phoenix rising from the ashes?

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2016年第1期11卷 64-65页

作者： Robert b.white Meghan G.Thomas School of Anatomy Physiology & Human Biology The University of Western Australia Parkinson’s Centre School of Medical Sciences Edith Cowan University Experimental and Regenerative Neuroscience School of Animal BiologyThe University of Western Australia

Few would doubt that understanding the developmental landscape from which a mature neuron is derived is essential to understand its *** temporal and spatial position of a cell from the very earliest stages of developm... 详细信息

关键词： landscape earliest mature doubt exposed developmental substantia nigra hydroxylase dopamine

Three-Dimensional boundary Element Method Applied to Nonlinear Wave Transformation

在线全文

学校读者我要写书评

暂无评论

China Ocean Engineering 1999年第2期14卷 163-170页

作者： Sun, dp Li, YC Teng, b Dalian Univ Technol State Key Lab Coastal & Offshore Engn Dalian 116023 Peoples R China

For higher accuracy in simulating the transformation of three dimensional waves, in consideration of the advantages of constant panels and linear elements, a combined boundary elements is applied in this research. The method can be used to remove the transverse vibration due to the accumulation of computational errors. A combined boundary condition of sponge layer and Sommerfeld radiation condition is used to remove the reflected waves from the computing domain. by following the water particle on the water surface, the third order Stokes wave transform is simulated by the numerical wave flume technique. The computed results are in good agreement with theoretical ones.

关键词： Laplace equation nonlinear wave 3D boundary element method combined elements

Modelling the development of biological structures displaying longitudinal geometries in vitro:culturing pluripotent stem cells on plasma-treated,growth factor-coupled polycaprolactone fibres

在线全文

学校读者我要写书评

暂无评论

Engineered Regeneration 2024年第1期5卷 124-138页

作者： badwi b.boumelhem Stuart T.Fraser Syamak Farajikhah Rachel A.Shparberg Michael b.Morris Marcela M.M.bilek Anyu Zhang behnam Akhavan Simon Fleming Maryanne Large School of Physics Faculty of ScienceUniversity of SydneyAustralia Sydney Nano Institute University of SydneyAustralia School of Chemical and biomolecular Engineering University of SydneyAustralia School of Medical Sciences Faculty of Medicine and HealthUniversity of SydneyAustralia School of biomedical Engineering Faculty of EngineeringUniversity of SydneyAustralia School of Engineering University of NewcastleCallaghanNSW 2308Australia Hunter Medical Research Institute(HMRI) Precision Medicine ProgramNew Lambton Heights NSW 2305Australia

Many biological structures such as nerves,blood and lymphatic vessels,and muscle fibres exhibit longitudinal ge-ometries with distinct cell types extending along both the length and width of internal linear *** these three-dimensional structures in vitro is challenging:the best-defined stem-cell differentiation systems are mono-layer cultures or organoids using pluripotent stem *** stem cells can differentiate into functionally mature cells depending on the signals received,holding great promise for regenerative ***,the integration of in vitro differentiated cell types into diseased tissue remains a *** scaffolds can bridge this gap if the appropriate signalling systems are incorporated into the ***,we have taken a biomimicry approach to generate longitudinal structures in *** this approach,mouse embryonic stem cells are directed to differentiate to specific cell types on the surface of polycaprolactone(PCL)fibres treated by plasma-immersion ion implantation and to which with lineage-specifying molecules have been covalently *** demonstrate the simplicity and utility of our method for efficiently generating high yields of the following cell types from these pluripotent stem cells:neurons,vascular endothelial cells,osteoclasts,adipocytes,and cells of the erythroid,myeloid,and lymphoid *** arranged plasma-treated scaffolds with differentiated cell types could ultimately serve as a means for the repair or treatment of diseased or damaged tissue.

关键词： Pluripotent stem cells Lineage commitment Growth factors biomaterial engineering Plasma-immersion ion implantation Covalent biomolecule attachment Polycaprolactone

Assessment of Defects and Collapsed Sites in Self-Assembled Alkanethiol Monolayer on Gold by Cyclic Voltammetry and ***

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Chemical Letters 1998年第12期9卷 0-0,0-0页

作者： Diao, P Jiang, DL Cui, XL Gu, dp Tong, RT Zhong, b Chinese Acad Sci Inst Coal Chem Taiyuan 030001 Peoples R China Hebei Teachers Univ Dept Chem Shijiazhuang 050016 Peoples R China

Self-assembly of octadecyl mercaptan on gold was investigated by cyclic voltammetry(CV) and electrochemical impedance spectroscopy (EIS). Results of CV experiments show thatthere are no structUral defects exposed directly to the redox couple in solution, but EISexperiments indicate that collapsed sites exist in the monolayer. A method to estimate the degree ofdisorder in the Au/thiol monolayer surface is proposed by using admittance plane plot.

关键词： Self-assembled monolayer cyclic voltammetry a.c. impedance ideally polarizable electrode surface roughness

Protein-activated atomic layer deposition for robust crude-oil-repellent hierarchical nano-armored membranes

在线全文

学校读者我要写书评

暂无评论

Science bulletin 2024年第2期69卷 218-226页

作者： Xiaobin Yang Pan Sun Yajie Wen Anil U.Mane Jeffrey W.Elam Jun Ma Shaomin Liu Seth b.Darling Lu Shao MIIT Key Laboratory of Critical Materials Technology for New Energy Conversion and Storage State Key Laboratory of Urban Water Resource and EnvironmentSchool of Chemistry and Chemical EngineeringHarbin Institute of TechnologyHarbin 150001China Chemical Sciences and Engineering Division Argonne National LaboratoryLemont IL 60439USA Applied Materials Division Argonne National LaboratoryLemont IL 60439USA Advanced Materials for Energy-Water Systems Energy Frontier Research Center Argonne National LaboratoryLemont IL 60439USA Pritzker School of Molecular Engineering University of ChicagoChicago IL 60637USA Department of Physics University of Ilinois at ChicagoChicago IL 60607USA School of Environment Harbin Institute of TechnologyHarbin 150090China WA School of Mines:Minerals Energy and Chemical EngineeringCurtin UniversityPerth WA 6845Australia

Atomic layer deposition(ALD)offers unique capabilities to fabricate atomically engineered porous materials with precise pore tuning and multi-functionalization for diverse applications like advanced membrane separations towards sustainable energy-water ***,current ALD technique is inhibited on most non-polar polymeric membranes due to lack of accessible nucleation ***,we report a facile method to efficiently promote ALD coating on hydrophobic surface of polymeric membranes via novel protein activation/*** a proof of concept,TiO2 ALD-coated membranes activated by bovine serum albumin exhibit remarkable superhydrophilicity,ultralow underwater crude oil adhesion,and robust tolerance to rigorous environments including acid,alkali,saline,and *** importantly,excellent cyclable crude oil-in-water emulsion separation performance can be *** mechanism for activation/sensitization is rooted in reactivity for a particular set of amino ***,the universality of protein-sensitized ALD is demonstrated using common egg white,promising numerous potential usages in biomedical engineering,environmental remediation,lowcarbon manufacturing,catalysis,and beyond.

关键词： Membrane separation Atomic layer deposition Water treatment Antifouling

Environmental drivers and genomic architecture of trait differentiation in fire-adapted banksia attenuata ecotypes

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Integrative Plant biology 2019年第4期61卷 417-432页

作者： Tianhua He byron b.Lamont neal J.Enright Haylee M.D'Agui William Stock School of Molecular and Life Sciences Curtin University School of Veterinary and Life Sciences Murdoch University Centre for Ecosystem Management Edith Cowan University

Trait divergence between populations is considered an adaptive response to different environments,but to what extent this response is accompanied by genetic differentiation is less clear since it may be phenotypic plasticity. In this study, we analyzed phenotypic variation between two banksia attenuata growth forms, lignotuberous(shrub) and epicormic resprouting(tree), in fire-prone environments to identify the environmental factors that have driven this phenotypic divergence. We linked genotype with phenotype and traced candidate genes using differential gene expression analysis. Fire intervals determined the phenotypic divergence between growth forms in b. attenuata. A genome-wide association study identified 69 single nucleotide polymorphisms, putatively associated with growth form, whereas no growth form-or phenotype-specific genotypes were eidentified. Genomic differentiation between the two growth forms was low(F_(st)=0.024). Differential gene expression analysis identified 37 genes/transcripts that were differentially expressed in the two growth forms. A small heat-shock protein gene, associated with lignotuber presence, was differentially expressed in the two *** conclude that different fire regimes induce phenotypic polymorphism in b. attenuata, whereas phenotypic trait divergence involves the differential expression of a small fraction of genes that interact strongly with the disturbance regime. Thus, phenotypic plasticity among resprouters is the general strategy for surviving varying fire regimes.

关键词： Environmental drivers genomic architecture trait differentiation

Epitaxially aligned single-crystal gold nanoplates formed in large-area arrays at high yield

在线全文

学校读者我要写书评

暂无评论

Nano Research 2022年第1期15卷 296-303页

作者： Trevor b.Demille Robert D.neal Arin S.Preston Zijuan Liang Allen G.Oliver Robert A.Hughes Svetlana Neretina College of Engineering University of Notre DameNotre DameIndiana 46556USA Department of Chemistry and biochemistry University of Notre DameNotre DameIndiana 46556USA

Well-tailored nanomaterials with a single-crystal character provide ideal building blocks for on-chip plasmonic *** colloidal methods have demonstrated mastery over the synthesis of such structures,it has proven quite difficult to deploy these same nanomaterials on substrate surfaces in a highly deterministic manner where precise control over position and orientation is ***,we demonstrate a room-temperature two-reagent liquid-phase seed-mediated synthesis of gold nanoplates directly on substrate surfaces in arrays over a square-centimeter *** synthesis is reliant on benchtop lithographic and directed-assembly processes that give rise to single-crystal seeds of gold that express both an epitaxial relationship with the underlying substrate and the internal defect structure required to promote a two-dimensional growth *** resulting structures are highly faceted and,because seed-substrate epitaxy is imposed upon the growing nanoplates,are identically aligned on the substrate *** yields are increased to values as high as 95%using a post-processing sonication procedure that selectively removes a small population of irregularly shaped nanostructures from the substrate surface,and in doing so,gives rise to an uncompromised plasmonic *** work,therefore,advances the techniques needed to integrate single-crystal nanomaterials with wafer-based technologies and provides leading-edge capabilities in terms of defining large-area arrays of plasmonic structures with the nanoplate geometry.

关键词： nanoplates epitaxial array plasmon brij-700 block copolymer substrate

MRbLES 2.0: High-throughput generation of chemically functionalized spectrally and magnetically encoded hydrogel beads using a simple single-layer microfluidic device

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Microsystems & Nanoengineering 2020年第1期6卷 145-157页

作者： Yinnian Feng Adam K.white Jamin b.Hein Eric A.Appel Polly M.Fordyce Department of Genetics Stanford UniversityStanfordCA 94305USA Department of bioengineering Stanford UniversityStanfordCA 94305USA Department of biology Stanford UniversityStanfordCA 94305USA The Novo Nordisk Foundation Center for Protein Research Faculty of Health and Medical SciencesUniversity of CopenhagenBlegdamsvej 3b2200 CopenhagenDenmark Department of Materials Science&Engineering Stanford UniversityStanfordCA 94305USA Stanford ChEM-H Stanford UniversityStanfordCA 94305USA Chan Zuckerberg biohub San FranciscoCA 94110USA

The widespread adoption of bead-based multiplexed bioassays requires the ability to easily synthesize encoded microspheres and conjugate analytes of interest to their ***,we present a simple method(MRbLEs 2.0)for the efficient high-throughput generation of microspheres with ratiometric barcode lanthanide encoding(MRbLEs)that bear functional groups for downstream surface *** production in MRbLEs 2.0 relies on the manual mixing of lanthanide/polymer mixtures(each of which comprises a unique spectral code)followed by droplet generation using single-layer,parallel flow-focusing devices and the off-chip batch polymerization of droplets into *** streamline downstream analyte coupling,MRbLEs 2.0 crosslinks copolymers bearing functional groups on the bead surface during bead *** the MRbLEs 2.0 pipeline,we generate monodisperse MRbLEs containing 48 distinct well-resolved spectral codes with high throughput(>150,000/min and can be boosted to 450,000/min).We further demonstrate the efficient conjugation of oligonucleotides and entire proteins to carboxyl MRbLEs and of biotin to amino ***,we show that MRbLEs can also be magnetized via the simultaneous incorporation of magnetic nanoparticles with only a minor decrease in the potential code *** the advantages of dramatically simplified device fabrication,elimination of the need for custom-made equipment,and the ability to produce spectrally and magnetically encoded beads with direct surface functionalization with high throughput,MRbLEs 2.0 can be directly applied by many labs towards a wide variety of downstream assays,from basic biology to diagnostics and other translational research.

关键词： beads spectral functional