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Biodynamic Practices, Eco-label Wines and Millennial Consumers

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Journal of Agricultural Science and Technology(A) 2012年第12期2卷 1364-1372页

作者： Michael McCullough Eivis Qenani neal MacDougall Agribusiness Department California Polytechnic State University San Luis Obispo CA 93407 USA

Abstract： The objective of this study was to provide insights on the motivations behind the decision of biodynamic producers in the United States to shift to biodynamic practices in the vineyard and winemaking process. The second objective of the study was to evaluate the perceptions of the consumers regarding eco-label wines, with a direct focus on the attitudes of millennial generation. Two surveys, one directed to biodynamic producers in the United States and the other to a group of Californian wine consumers were distributed during spring and fall of 2010. Findings from the first survey reveal that biodynamic producers are engaged in biodynamic practices out of socially motivated reasons rather than economic factors. Results from the consumer survey suggest a generally uninformed generation of consumers about eco-label wines and particularly about the practices associated with these products. This lack of information heavily influences their behavioral decisions and attitudes and points out to the critical need for consumer education.

关键词： Eco-label wine biodynamic wine biodynamic practices millennial consumers Chi-square tests total word count:4 555.

Failure of P-selectin blockade alone to protect the liver from ischemia-reperfusion injury in the isolated blood-perfused rat liver

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World Journal of Gastroenterology 2008年第44期14卷 6808-6816页

作者： Samuel Wyllie neal R Barshes Saul J Karpen John A Goss Michael E. DeBakey Department of Surgery Liver Transplant Center LaboratoryBaylor College of MedicineHoustonTX 77030United States

AIM： To determine if blockade of P-selectin in the isolated blood-perfused cold ex vivo rat liver model protects the liver from ischemia-reperfusion injury. METHODS： The effect of P-selectin blockade was assessed by employing an isolated blood-perfused cold ex vivo rat liver with or without P-selectin antibody treatment before and after 6 h of cold storage in University of Wisconsin solution. RESULTS： In our isolated blood-perfused rat liver model, pre-treatment with P-selectin antibody failed to protect the liver from ischemia-reperfusion injury, as judged by the elevated aspartate aminotransferase activity. In addition, P-selectin antibody treatment did not significantly reduced hepatic polymorphonuclear leukocyte accumulation after 120 min of perfusion. Histological evaluation of liver sections obtained at 120 min of perfusion showed significant oncotic necrosis in liver sections of both ischemic control and P-selectin antibody-treated groups. However, total bile production after 120 rain of perfusion was significantly greater in P-selectin antibody-treated livers, compared to control livers. No significant difference in P-selectin and ICAM-1 mRNAs and proteins, GSH, GSSG, and nuclear NF-kB was found between control and P-selectin antibody-treated livers. CONCLUSION： In conclusion, we have shown that blockade of P-selectin alone failed to reduced polymorphonuclear leukocyte accumulation in the liver and protect hepatocytes from ischemia-reperfusion injury in the isolated blood-perfused cold-ex vivo rat liver model.

关键词： P-selectin Ischemia-reperfusion Antibody-blockade Liver Rat

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函数式编程思维

Zero-waste emission design of sustainable and programmable actuators

作者： (美)neal Ford

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SusMat 2023年第2期3卷 207-221页

作者： Linchao Sun Lixuan Che Ming Li William George neal Xu Leng Yaojia Long Yifeng Jia Yunhu Gao Matteo Palma Yao Lu Department of Chemistry School of Physical and Chemical SciencesQueen Mary University of LondonLondonUK State Key Laboratory of Structural Analysis for Industrial Equipment Dalian University of TechnologyDalianChina Chemistry Research Laboratory Department of ChemistryUniversity of OxfordOxfordUK Department of Engineering University of CambridgeCambridgeUK

Moisture-responsive actuators are widely used as energy-harvesting devices due to their excellent ability to spontaneously and continuously convert external energy into kinetic ***,it remains a challenge to sustainably synthesize moisture-driven ***,we present a sustainable zero-waste emission methodology to prepare soft actuators using carbon nano-powders and biodegradable polymers through a water evaporation *** to the water solubility and recyclability of the matrixes employed here,the entire synthetic process achieves zero-waste *** composite films featured strong figures of merit and capabilities with a 250◦maximum bending angle under 90%relative *** motions and intelligent bionic applications,including walkers,smart switches,robotic arms,flexible excavators,and hand-shaped actuators,were further achieved by modulating the geometry of the *** sustainable method for actuators’fabrication has great potential in large-scale productions and applications due to its advantages of zero-waste emission manufacturing,excellent recyclability,inherent adaptive integration,and low cost.

关键词： programmable motions recyclability sustainable actuators zero-waste emission

Fabrication and multiscale characterization of 3D silver containing bioactive glass-ceramic scaffolds

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Bioactive Materials 2019年第1期4卷 215-223页

作者： Adam C.Marsh Nathan P.Mellott Natalia Pajares-Chamorro Martin Crimp Anthony Wren neal D.Hammer Xanthippi Chatzistavrou Department of Chemical Engineering&Materials Science Michigan State UniversityEast LansingMIUSA Alfred University Kazuo Inamori School of EngineeringAlfredNYUSA Department of Microbiology&Molecular Genetics Michigan State UniversityEast LansingMIUSA

In this work,we fabricated and characterized bioactive 3D glass-ceramic scaffolds with inherent antibacterial *** sol-gel(solution-gelation)technique and the sacrificial template method were applied for the fabrication of 3D highly porous scaffolds in the 58.6SiO2-24.9CaO-7.2P2O5-4.2Al2O3–1.5Na2O−1.5K2O–2.1Ag2O system(Ag-BG).This system is known for its advanced bioactive and antibacterial *** fabrication of 3D scaffolds has potential applications that impact tissue *** study of the developed scaffolds from macro-characteristics to nano-,revealed a strong correlation between the macroscale properties such as antibacterial action,bioactivity with the microstructural characteristics such as elemental analysis,*** homogeneity,morphological,and microstructural characteristics of the scaffolds were studied by scanning electron microscopy associated with energy dispersive spectroscopy(SEM-EDS),transmittance electron microscopy(TEM),X-ray diffraction(XRD),X-ray photoelectron spectroscopy(XPS),Fourier transform infrared spectroscopy(FTIR),and UV-visible spectroscopy *** compressive strength of the 3D scaffolds was measured within the range of values for glass-ceramic scaffolds with similar compositions,porosity,and pore *** capability of the scaffolds to form an apatite-like phase was tested by immersing the scaffolds in simulated body fluid(SBF)and the antibacterial response against methicillin-resistant Staphylococcus aureus(MRSA)was *** formation of an apatite phase was observed after two weeks of immersion in SBF and the anti-MRSA effect occurs after both direct and indirect exposure.

关键词： 3D glass-ceramic scaffolds Nano and macro structural properties Bioactivity Antibacterial properties Silver

Genetic association and epistatic interaction of the interleukin-10 signaling pathway in pediatric inflammatory bowel disease

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World Journal of Gastroenterology 2017年第27期23卷 4897-4909页

作者： Zhenwu Lin Zhong Wang John P Hegarty Tony R Lin Yunhua Wang Sue Deiling Rongling Wu neal J Thomas Joanna Floros CHILD Research Department of Pediatricsthe Pennsylvania State UniversityCollege of Medicine Department of Radiology University of Pennsylvania Perelman School of Medicine Division of Biostatistics Department of Public Health Sciencethe Pennsylvania State UniversityCollege of Medicine Department of Surgery the Pennsylvania State UniversityCollege of Medicine Department of Obstetrics and Gynecology the Pennsylvania State UniversityCollege of Medicine

To study the genetic association and epistatic interaction of the interleukin (IL)-10 and IL-10/STAT3 pathways in pediatric inflammatory bowel disease (IBD). METHODSA total of 159 pediatric inflammatory IBD patients (Crohn’s disease, n = 136; ulcerative colitis, n = 23) and 129 matched controls were studied for genetic association of selected single nucleotide polymorphisms (SNPs) of the IL-10 gene and the genes IL10RA, IL10RB, STAT3, and HO1, from the IL-10/STAT3 signaling pathway. As interactions between SNPs from different loci may significantly affect the associated risk for disease, additive (a) and dominant (d) modeling of SNP interactions was also performed to examine high-order epistasis between combinations of the individual SNPs. RESULTSThe results showed that IL-10 rs304496 was associated with pediatric IBD (P = 0.022), but no association was found for two other IL-10 SNPs, rs1800872 and rs2034498, or for SNPs in genes IL10RA, IL10RB, STAT3, and HO1. However, analysis of epistatic interaction among these genes showed significant interactions: (1) between two IL-10 SNPs rs1800872 and rs3024496 (additive-additive P = 0.00015, Bonferroni P value (Bp) = 0.003); (2) between IL-10RB rs2834167 and HO1 rs2071746 (dominant-additive, P = 0.0018, Bp = 0.039); and (3) among IL-10 rs1800872, IL10RB rs2834167, and HO1 rs2071746 (additive-dominant-additive, P = 0.00015, Bp = 0.005), as well as weak interactions among IL-10 rs1800872, IL-10 rs3024496, and IL-10RA (additive-additive-additive, P = 0.003; Bp = 0.099), and among IL10RA, IL10RB, and HO1 genes (additive-dominant-additive, P = 0.008, Bp = 0.287). CONCLUSIONThese results indicate that both the IL-10 gene itself, and through epistatic interaction with genes within the IL-10/STAT3 signaling pathway, contribute to the risk of pediatric IBD.

关键词： Pediatric inflammatory bowel disease Interleukin-10 HO1 Single nucleotide polymorphism IL10-STAT3 pathway Epistatic interaction

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美国现代化客车修理基地

国外铁道车辆 1991年第4期28卷 48-51页

作者： neal Necastro 张雄

本文介绍美国长岛新建的一个现代化客车综合修理基地。该基地的自动化程度较高,采用机器人清洗,可检修转向架、制动机、空调机等各种客车部件。

关键词：维修客车美国车辆

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Springing

小学生时代（大嘴英语） 2023年第3期 18-19页

作者： neal Levin Michelle Hazelwood Hyde(图) 不详

How delightful!Spring is bringing everything a new *** is *** are *** are ***,*** in the park areswinging.I'm so happy spring is springing,Spring is coming.春姑娘悄悄向我们走来,挥一挥衣袖,万物复苏。ning鸟儿在歌唱,虫儿在鸣叫。草儿探着头,花儿羞答答地笑。Spring is *** is shining.你的世界里,还有哪些正在“进行时”?

关键词： Spring spring bringing

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The Birthday Worm

小学生时代（大嘴英语） 2022年第9期 18-22页

作者： Maggie Murphy Juana Martinez-neal(图) 不详