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Updated bone mineral density status in Saudi patients with inflammatory bowel disease

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World Journal of Gastroenterology 2020年第35期26卷 5343-5353页

作者： Mohammed Ewid Nawaf Al Mutiri Khalid Al Omar Amal N Shamsan Awais A Rathore nazmus saquib Anas Salaas Omar Al Sarraj Yaman Nasri Ahmed Attal Abdulrahman Tawfiq Hossam Sherif Internal Medicine Department College of MedicineSulaiman Al Rajhi UniversityBukairyah 51941Al-QassimSaudi Arabia Internal Medicine Department Faculty of MedicineCairo UniversityCairo 11562Egypt Gastroenterology Department King Fahad Specialist HospitalBuraidah 52366Al-QassimSaudi Arabia Epidemiology Department College of MedicineSulaiman Al Rajhi UniversityBukairyah 51941Al-QassimSaudi Arabia Medical students College of MedicineSulaiman Al Rajhi UniversityBukairyah 51941Al-QassimSaudi Arabia Critical Care Medicine Department College of MedicineSulaiman Al Rajhi UniversityBukairyah 51941Al-QassimSaudi Arabia Critical Care Medicine Department Faculty of MedicineCairo UniversityCairo 11562Egypt

BACKGROUND Little is known about inflammatory bowel disease(IBD)burden and its impact on bone mineral density(BMD)among adult patients in Saudi *** the best of our knowledge,our study is the only study to give an update about this health problem in adult Saudi patients with *** is a great risk factor for reduced BMD due to its associated chronic inflammation,malabsorption,weight loss and medication side ***,screening for reduced BMD among patients with IBD is of utmost importance to curb and control anticipated morbidity and mortality among those *** To assess the relationship between IBD and BMD in a sample of adult Saudi patients with *** Ninety adult patients with IBD-62 Crohn’s disease(CD)and 28 ulcerative colitis(UC)-were recruited from King Fahad Specialist Hospital gastroenterology clinics in Buraidah,*** enrolled patients were interviewed for their demographic information and for IBD-and BMD-related clinical *** patients had the necessary laboratory markers and dual-energy x-ray absorptiometry scans to evaluate their BMD *** were divided into two groups(CD and UC)to explore their clinical characteristics and possible risk factors for reduced *** The CD group was significantly more prone to osteopenia and osteoporosis compared to the UC group;44%of the CD patients had normal BMD,19%had osteopenia,and 37%had osteoporosis,while 78%of the UC patients had normal BMD,7%had osteopenia,and 25%had osteoporosis(P value<0.05).In the CD group,the lowest t-score showed a statistically significant correlation with body mass index(BMI)(r=0.45,P<0.001),lumbar z-score(r=0.77,P<0.05)and femur z-score(r=0.85,P<0.05).In the UC group,the lowest t-score showed only statistically significant correlation with the lumbar z-score(r=0.82,P<0.05)and femur z-score(r=0.80,P<0.05).The ROC-curve showed that low BMI could predict the lowest t-score in the CD group with the best cut-off value at≤23.43(m/kg2);area

关键词： Inflammatory bowel disease Crohn’s disease Ulcerative colitis Bone mineral density Osteoporosis Fracture risk

Peptic Ulcer Diseases among Migrant Workers in Saudi Arabia

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Journal of Biosciences and Medicines 2024年第11期12卷 57-69页

作者： Nahlah Alsogaih Juliann saquib Rashid Alshammari Muneeb Qayyum Muath Alzughabi Khalid Alkhiari Ahmed Dildar Abdulrahman Almazrou nazmus saquib College of Medicine Sulaiman Al Rajhi University Al Bukayriyah Saudi Arabia

Background: Although migrant workers make up nearly one-third of the Saudi population, there is no data on peptic ulcer diseases (PUD) among them. We aimed to assess the prevalence and risk factors of PUD in a sample of migrant workers in Saudi Arabia. Methods: Migrant workers (n = 2123) from seven different occupations (i.e., auto repair, construction, hairdressers, hospital cleaners, poultry factory, restaurants, and city cleaners) from Al Qassim province in Saudi Arabia participated in this cross-sectional study. They were interviewed using a standardized questionnaire on demography, lifestyle, job factors, and chronic health conditions. A worker had PUD if he reported having this condition diagnosed by a physician and was taking medication for it. Binary logistic regression was employed to explore risk factors of PUD. Results: The mean age (standard deviation) was 35 ± 9 years. The prevalence of PUD was 4% and varied by occupation, with the highest among auto-repair workers (8.3%) and the lowest among construction workers (1.8%). Lifestyle characteristics such as diet, self-rated health status, smoking, and stress, were significantly associated with peptic ulcers. Conclusion: The prevalence of peptic ulcers among migrant workers in Saudi Arabia (4%) was not significantly different from the general population or the global prevalence of 5% - 10%. Further studies are needed to validate these findings.

关键词： Epidemiology Migrant Workers Occupation Peptic Ulcer Disease Saudi Arabia

Quality Assessment of Online Patient Education Materials for Diabetic Foot

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Journal of Biosciences and Medicines 2024年第9期12卷 28-41页

作者： Dana Hendie Eyman Haj-Ali Muhammad Candragupta Jihwaprani Hagar Khaled Marah Alrahal Faisal Zain Mohammed Al-Zabidi nazmus saquib Juliann saquib College of Medicine Sulaiman Al Rajhi University Bukaryiah Saudi Arabia

Background: The quality of online Arabic educational materials for diabetic foot syndrome (DFS) is unknown. This study evaluated Arabic websites as patients’ sources of information for DFS. Methods: The study assessed patient-related websites about DFS using a modified Ensuring Quality of Information for Patients (EQIP) tool (score 0 - 35). Specific terms were searched in Google to identify DFS websites;eligibility criteria were applied to 20 pages of search results to select the included websites. Data on country of origin, source types and subtypes, and website traffic were extracted. Additional therapeutic information regarding prevention and conservative, pharmacological, and surgical treatments was also recorded and analyzed. Results: Among 559 websites, 157 were eligible for inclusion. The median EQIP score was 16 out of 35, indicating poor quality in one of three domains (content, identification, or structure). Most sources originated from Arab countries (75.8%) were non-governmental (94.9%), and were medical information websites (46.5%). High-scoring websites were significantly more likely than low-scoring websites to describe information on prevention (30.9% vs. 2.9%, p = 0.001), conservative treatment (34.1% vs. 13%, p = 0.002), or pharmacological treatment (32.5% vs. 16.8%, p = 0.024). There were increased odds of scoring high if a website provided information on prevention (OR = 12.9, 95% CI [1.68 - 98.57], p = 0.014). Conclusion: Most Arabic online patient information on DFS is of poor quality. Quality control measures are needed to ensure accurate health information for the public.

关键词： Diabetic Foot Disease Diabetic Foot Ulcer Online Resources Patient Education Patient Education Materials

Exploring the Role of Serum Cystatin C in Early Detection of Acute Kidney Injury among On-Pump Cardiac Surgery Patients: A Single-Center Investigation in Bangladesh

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World Journal of Cardiovascular Diseases 2024年第6期14卷 363-373页

作者： Md. Ahaduzzaman Md. Abir Tazim Chowdhury Munama Magdum Md. Saiful Islam Khan Satyajit Sharma Monoj Tiwari Md. Abul Bashar Maruf Md. Alauddin Omar Sadeque Khan Md. Mostafizur Rahman Mirza Md. nazmus saquib Department of Cardiothoracic and Vascular Surgery Evercare Hospital Dhaka Dhaka Bangladesh Department of Preventive and Social Medicine National Institute of Preventive and Social Medicine Dhaka Bangladesh Department of Cardiothoracic Anesthesia Evercare Hospital Dhaka Dhaka Bangladesh Department of Cardiac Surgery National Heart Foundation Hospital & Research Institute Dhaka Bangladesh Department of Cardiovascular and Thoracic Surgery B.P. Koirala Memorial Cancer Hospital Bharatpur Chitwan Nepal Department of Cardiac Surgery United Hospital Limited Dhaka Bangladesh Department of Cardiac Surgery Bangabandhu Sheikh Mujib Medical University Dhaka Bangladesh Department of Cardiac Surgery Ibrahim Cardiac Hospital & Research Institute Dhaka Bangladesh

Background: Acute Kidney Injury (AKI) stands as a prominent postoperative complication in on-pump cardiac surgery, with repercussions on morbidity, mortality, and hospitalization duration. Current diagnostic criteria relying on serum creatinine levels exhibit a delayed identification of AKI, prompting an exploration of alternative biomarkers. Aims and Objectives: This study is designed to overcome diagnostic constraints and explore the viability of serum Cystatin C as an early predictor of Acute Kidney Injury (AKI) in individuals undergoing on-pump cardiac surgery. The investigation aims to establish the relationship between serum Cystatin C levels and the onset of AKI in patients subjected to on-pump cardiac surgery. Primary objectives involve the assessment of the diagnostic effectiveness of serum Cystatin C, its comparison with serum creatinine, and the exploration of its potential for the early identification and treatment of AKI. Methodology: Conducted as a single-center study at the cardiac surgery department of BSMMU in Bangladesh from September 2020 to August 2022, a comparative cross-sectional analysis involved 31 participants categorized into No AKI and AKI groups based on Kidney Disease: Improving Global Outcomes (KDIGO) criteria. Data collection encompassed preoperative, post-CBP (cardiopulmonary bypass) conclusion at 2 hours, postoperative day 1, and postoperative day 2 intervals. Statistical analyses included Chi-squared tests, independent Student’s t-tests, and one-sample t-tests. Significance was set at P Results: The study revealed no significant differences in baseline characteristics between the No AKI and AKI groups, except for CPB time and cross-clamp time. Serum Cystatin C levels in the AKI group exhibited statistical significance at various time points, highlighting its potential as an early detector. Conversely, Serum Creatinine levels in the AKI group showed no statistical significance. The Receiver Operating Characteristic (ROC) curve analy

关键词： Acute Kidney Injury (AKI) On-Pump Cardiac Surgery Serum Cystatin C Serum Creatinine Diagnostic Biomarkers Early Detection Cardiopulmonary Bypass Single-Center Study Bangladesh