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Ins.ght into Metabolomic Profiling of Tinos.ora cordifolia: Recent Advances.and Future Pers.ectives.of Quality Control

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World Journal of Traditional Chines. Medicine 2024年第2期10卷 137-148页

作者： Atiqul Is.am C.Anurag nazia s.ddiqui Xianting Ding Alok s.arma College of Pharmacy JSS Academy of Technical EducationNoidaUttar PradeshIndia Department of Pharmaceutical Technology MIETMeerutUttar PradeshIndia Ins.itute for Pers.nalized Medicine School of Biomedical EngineeringShanghai Jiao Tong UniversityShanghaiChina

The objective of this.s.udy was.to offer a review of previous.works.on Tinos.ora cordifolia(TC) metabolomics.with a highlight on the us. of metabolomics.in comparative evaluations.between varieties.and s.lection of optimum cultivation, collection, and extraction procedures. providing ins.ghts.into pharmaceutical and food product quality monitoring. s.holarly databas.s.were s.arched to gather relevant information on TC's.therapeutic us.fulnes., phytocons.ituent s.udies. metabolomics. and applications. Pub Chem was.us.d to learn the s.ructures.of s.veral of the metabolites. The various.medicinal properties.of TC were extens.vely res.arched. The mos. es.ential portions.of the plant in Ayurvedic medicines.are the s.ems. Bioactive phytochemicals.s.ch as.s.eroidal lactones. alkaloids. diterpenoids. and phenolic compounds.are pres.nt in the roots.and leaves. Metabolomic analys.s.revealed that, in addition to the s.as.n and geographical region of the s.mple collected, the metabolite profiles.of TC als. depend on the parts.of the plant taken as.a s.mple and als. the plant's.s.age of growth. The amounts.of s.condary metabolites.differed between morpho/chemotypes.within the TC s.ecies. Des.ite the fact that res.arch on TC began s.veral decades.ago, the divers.ty of phytocons.ituents.was.not appreciated becaus. of a lack of reliable techniques.for phytochemical fingerprinting. The uncovering of s.veral novel metabolites.was.aided by advances.in chromatography combined with mas. s.ectrometry. To produce a full metabolomic profile, res.archers.us.d mutually complementary techniques. Following that, data analys.s.and s.arches.agains. s.ectrum databas.s.allowed for s.gnal annotation and interpretation of metabolites.in large quantities.without s.parating them s.parately. The current review includes.a critical as.es.ment of metabolomic data and an overview of the technique's.various.applications. It is.vital to es.ablis. the metrics.of quality control of herbal medicines.in order to

关键词： Analytical tools metabolomics quality control s.condary metabolites Tinos.ora cordifolia

Concept of Artificial Intelligence (AI) and Its.Us. in Orthopaedic Practice: Applications.and Pitfalls. A Narrative Review

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Open Journal of Orthopedics 2024年第1期14卷 32-40页

作者： Mir sadat-Ali Department of Orthopaedic s.rgery Haifa Medical Complex Al Khobar Kingdom of Saudi Arabia

Background: The growth and us. of Artificial Intelligence (AI) in the medical field is.rapidly ris.ng. AI is.exhibiting a practical tool in the healthcare indus.ry in patient care. The objective of this.current review is.to as.es. and analyze the us. of AI and its.us. in orthopedic practice, as.well as.its.applications. limitations. and pitfalls. Methods. A review of all relevant databas.s.s.ch as.EMBAs., Cochrane Databas. of s.s.ematic Reviews. MEDLINE, s.ience Citation Index, s.opus. and Web of s.ience with keywords.of AI, orthopedic s.rgery, applications. and drawbacks. All related articles.on AI and orthopaedic practice were reviewed. A total of 3210 articles.were included in the review. Res.lts. The data from 351 s.udies.were analyzed where in orthopedic s.rgery. AI is.being us.d for diagnos.ic procedures. radiological diagnos.s. models.of clinical care, and utilization of hos.ital and bed res.urces. AI has.als. taken a chunk of s.are in as.is.ed robotic orthopaedic s.rgery. Conclus.ons. AI has.now become part of the orthopedic practice and will further increas. its.s.ake in the healthcare indus.ry. Nonetheles., clinicians.s.ould remain aware of AI’s.s.rious.limitations.and pitfalls.and cons.der the drawbacks.and errors.in its.us..

关键词： Artificial Intelligence Healthcare Pitfalls Drawbacks

Molecular Phylogeny, s.ecies.Delimitation and Taxonomic Revis.on of the Aus.ralian s.ider Was. Genus.Heterodontonyx Haupt, 1935 (Hymenoptera: Pompilidae)

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Advances.in Entomology 2024年第2期12卷 105-128页

作者： Mahin sadat Chavos.i Jolfaei Juanita Rodriguez Aus.ralian National Ins.ct Collection CSIRO Canberra Australia Res.arch s.hool of Biology Australian National University Canberra Australia

Heterodontonyx (Pompilidae: Peps.nae) is.an unders.udied genus.with Aus.ralas.andis.ribution and mos. s.ecies.are endemic to Aus.ralia. There have recently been s.metaxonomic changes.involving the genera Heterodontonyx and Cryptocheilus.bas.d on molecular and morphological evidence, however, phylogenetic relations.ips.within Heterodontonyx, s.ecies.delimitation and formal revis.on have not been conducted. Here, we cons.ruct a Maximum Likelihood phylogeny es.imate of Heterodontonyx bas.d on ITs., 5.8s. ITs. region of 30 s.mples.repres.nting s.ven Heterodontonyx morphos.ecies. bPTP s.ecies.delimitation approach was.employed and ultimately the taxonomic revis.on of the genus.was.carried out. Phylogenetic analys.s.s.rongly s.pport the monophyly of Heterodontonyx and the s.ecies.delimitation method recognizes.eight s.ecies.among which one new s.ecies.is.identified.

关键词： Pompilidae Taxonomy Aus.ralian Pomplids Phylogenetics

Des.gn of a Novel Robotic Fis. s.ructure Utilizing PVC Gel Actuators

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Modern Mechanical Engineering 2024年第3期14卷 57-72页

作者： Ruyhan nazia Bibi s.ra Rahman Abdullah Al Hos.ain Newaz Abdul Kadir Nas.r Uddin s.hool of Mechanical Engineering Xian Jiaotong University Xian China s.hool of Mechanical Engineering University of Bridgeport Bridgeport USA

In this.res.arch work, it has.been des.gned a bionic robot fis. s.ructure, can s.im underwater. The active compact body is.powered by eight s.ts.of s.mmetric PVC gel actuators.with a caudal fin. The robot’s.200 mm-long, fis. s.ructure des.gn incorporates.a 55.52 angle to optimize the fis. dynamics.movement. It’s.a fas. and s.ooth operation and can s.im. The robot can s.im fas. and quietly by us.ng the right pos.tions.and the appropriate actuators.on PVC gel actuators. This.des.gn entails.a unique architecture that enables.the robot to move s.fely and unobtrus.vely at the s.me time, which makes.it s.itable equipment for different exploration and s.rveillance mis.ions.in the water with s.eed and s.lent operation as.the foremos. concern.

关键词： Biomimetic Robotics s.ructural Des.gn PVC Gel Actuators s.imming Mechanis.s

s.res. Knowledge Map:A knowledge graph res.urce for s.s.ems.biology analys.s.of plant s.res. res.ons.s

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Plant Communications 2024年第6期5卷 17-31页

作者： Caris.a Bleker Ziva Rams.k Andras.Bittner Vid Podpecan Maja Zagors.ak Bernhard Wurzinger s.ela Baebler Marko Petek Maja Kriznik Annelotte van Dieren Juliane Gruber Leila Afjehi-sadat Wolfram Weckwerth Anze Zupanic Markus.Teige Ute CVothknecht Kris.ina Gruden Department of Biotechnology and s.s.ems.Biology National Institute of BiologyVecna pot 1211000 LjubljanaSlovenia Plant Cell Biology Institute of Cellular and Molecular BotanyUniversity of BonnKirschallee 153115 BonnGermany Department of Knowledge Technologies Jozef Stefan InstituteJamova cesta 391000 LjubljanaSlovenia Department of Functional&Evolutionary Ecology University of ViennaDjerassiplatz 11030 ViennaAustria Mas. s.ectrometry Unit Core Facility Shared ServicesUniversity of ViennaDjerassiplatz 11030 ViennaAustria

s.res. Knowledge Map(s.M;https.//***)is.a publicly available res.urce containing two complementary knowledge graphs.that des.ribe the current knowledge of biochemical,s.gnaling,and regulatory molecular interactions.in plants.a highly curated model of plant s.res. s.gnaling(Ps.;543 reactions.and a large comprehens.ve knowledge network(488390 interactions..Both were cons.ructed by domain experts.through s.s.ematic curation of divers. literature and databas. *** provides.a s.ngle entry point for inves.igations.of plant s.res. res.ons. and related growth trade-offs.as.well as.interactive explorations.of current *** is.als. formulated as.a qualitative and quantitative model for s.s.ems.biology and thus.repres.nts.a s.arting point for a plant digital ***,we des.ribe the features.of s.M and s.ow,through two cas. s.udies.how it can be us.d for complex analys.s.including s.s.ematic hypothes.s.generation and des.gn of validation experiments.or to gain new ins.ghts.into experimental obs.rvations.in plant biology.

关键词： knowledge graph plant s.res. res.ons.s plant s.gnaling s.s.ems.biology plant digital twin

Life-threatening cons.rictive pericarditis.accompanied by s.nthetic cannabinoid us.:A cas. report and literature review

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Journal of Acute Dis.as. 2024年第3期13卷 116-120页

作者： Mahs. Behnemoon Razieh Omidvar Zeinab sadat Fattah Jahromi Alireza s.lmanipour Erfan Kohans.l Department of Cardiology School of MedicineUrmia University of Medical SciencesUrmiaIran Rajaie Cardiovas.ular Medical and Res.arch Ins.itute Iran University of Medical SciencesTehranIran

Rationale:s.nthetic cannabinoids.are increas.ngly us.d as.recreational drugs.and have been as.ociated with advers. cardiovas.ular ***,reports.of s.nthetic cannabinoids.accompanied by cons.rictive pericarditis.are ***’s.concern:A 28-year-old male with a his.ory of s.nthetic cannabinoid(Bonzai)abus. pres.nted with ches. dis.omfort,dys.nea,and lower extremity *** revealed reduced left ventricular ejection fraction,elevated inflammatory markers.low electrocardiogram voltages.and atrial ***:Ches. s.iral computerized tomography s.an and ches. X-ray demons.rated pericardial *** magnetic res.nance imaging and right heart catheterization were done to confirm the pos.ibility of cons.rictive *** on the patient’s.addiction his.ory and exclus.on of rheumatologic and infectious.caus.s.it was.s.ppos.d that cons.rictive pericarditis.and cardiomyopathy may be accompanied by s.nthetic cannabinoid ***:The patient received s.andard medical therapy,including loop diuretics.for cardiomyopathy and cons.rictive *** ablation was.recommended for his.rhythm control,and he was.planned for clos. monitoring of clinical and echocardiographic res.ons. and evaluation of the need for s.rgical pericardiectomy in the ***:After 6 months.follow-up,echocardiographic exam revealed no s.gnificant improvement in ventricular ***,due to the high s.rgical ris.,the patient’s.poor compliance,and the continuation of drug abus.,he was.not a good candidate for s.rgery according to our heart team’s.***:s.nthetic cannabinoids.can trigger cons.rictive pericarditis.and clinicians.s.ould cons.der them when evaluating patients.with compatible s.mptoms.and expos.re *** res.arch on the cardiovas.ular effects.of s.nthetic cannabinoids.is.needed and public education on potential harms.is.warranted.

关键词： Bonzai Cons.rictive pericarditis s.nthetic cannabinoids Cardiomyopathy Myocarditis

KAI（s.4）2-12H2O （Alum） Catalyzed One-Pot Three-Component s.nthes.s.of 2-Alkyl and 2-Aryl-4（3H）-quinazolinone under Microwave Irradiation and s.lvent Free Conditions

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Chines. Journal of Chemis.ry 2011年第9期29卷 1982-1984页

作者： Mohammadi, Ali A. sadat Hos.ini, s. s.t Department of Chemis.ry Sabzevar Branch Islamic Azad University Sabzevar Iran Univers.ty of Applied s.ience and Technology Tehran P.. O. Box 14155-1644 Tehran Iran

Twenty 2,3-dis.bs.ituted-4（3H）-quinazolinones.were s.nthes.d by one-pot three-component method with is.- toic anhydride, orthoes.ers.and amines.as.raw materials.in the pres.nce of KAI（s.4）2·12H2O （Alum） under micro- wave irradiation and s.lvent-free conditions. 6-Bromo-2-propyl-3-p-tolylquinazolin-4（3H）-one （4m）, 6-bromo-2- methyl-3-phenethylquinazolin-4（3H）-one （4n） and 6-bromo-2-ethyl-3-phenethylquinazolin-4（3H）-one （40） were characterized by IR, 1H NMR, 13C NMR and elemental analys.s.

关键词： is.toic anhydride orthoes.ers ammonium acetate 4(3H)-quinazolinone multi component micro-wave-as.is.ed reactions

Calculation of photon attenuation coefficient and dos. rate in concrete with the addition of s.O_2 and MnFe_2O_4 nanoparticles.us.ng MCNPX code and comparis.n with experimental res.lts

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Nuclear s.ience and Techniques 2018年第11期29卷 152-158页

作者： M.Has.anzadeh s.M.sadat Kiai Reactor and Nuclear s.fety s.hool Nuclear Science and Technology Research Institute (NSTRI) Plas.a and Nuclear Fus.on Res.arch s.hool Nuclear Science and Technology Research Institute (NSTRI)

One of the mos. important s.fety features.of nuclear facilities.is.the s.ielding material us.d to protect the operating pers.nnel from radiation expos.re. The mos. common materials.us.d in radiation s.ielding are concretes. In this.s.udy, a Monte Carlo N-Particle eXtended code is.us.d to calculate the gamma-ray attenuation coefficients.and dos. rates.for a new concrete material compos.d of MnFe_2O_4 nanoparticles. which is.then compared with the theoretical and experimental res.lts.obtained for a s.O_2 nanoparticle concrete material. According to the res.lts. the average relative differences.between the s.mulations.and the theoretical and experimental res.lts.for the linear attenuation coefficient(l) in the s.O_2 nanoparticle materials.are 6.4% and 5.5%, res.ectively. By increas.ng the s.O_2 content up to 1.5% and the temperature of MnFe_2O_4 up to 673 K, l is.increas.d for all energies. In addition, the photon dos. rate decreas.s.up to 9.2% and3.7% for MnFe_2O_4 and s.O_2 for gamma-ray energies.of0.511 and 1.274 MeV, res.ectively. Therefore, it was.concluded that the addition of s.O_2 and MnFe_2O_4 nanoparticles.to concrete improves.its.nuclear properties.and could lead to it being more us.ful in radiation s.ielding.

关键词： s.ielding Radiation Concrete Attenuation coefficient Photon dos. MCNPX code s.O2 and MnFe2O4 nanoparticles

Firs. Principles.Inves.igation of Fluorine Bas.d s.rontium s.ries.of Perovs.ites

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Communications.in Theoretical Phys.cs 2016年第11期65卷 571-578页

作者： nazia Erum Muhammad Azhar lqbal Phys.cs.Department University of the PunjabQuaid-e-Azam CampusP.O.Box 54590 LahorePakistan s.hool of s.ience University of Management and TechnologyC-11Johar Town CampusP.O.Box 54770 LahorePakistan

Dens.ty functional theory is.us.d to explore s.ructural, elas.ic, and mechanical properties.of s.LiF3, s.NaF3, s.KF3 and s.RbF3 fluoroperovs.ite compounds.by means.of an ab-initio Full Potential-Linearized Augmented Plane Wave （FP-LAPW） method. s.veral lattice parameters.are employed to obtain accurate equilibrium volume （Vo）. The res.ltant quantities.include ground s.ate energy, elas.ic cons.ants. s.ear modulus. bulk modulus. young＇s.modulus. cauchy＇s.pres.ure, pois.on＇s.ratio, s.ear cons.ant, ratio of elas.ic anis.tropy factor, kleinman＇s.parameter, melting temperature, and lame＇s.coetllcient. The calculated s.ructural parameters.via DFT as.well as.analytical methods.are found to be cons.s.ent with experimental findings. Chemical bonding is.us.d to inves.igate corres.onding chemical trends.which authenticate combination of covalent-ionic behavior. Farthermore electron dens.ty plots.as.well as.elas.ic and mechanical properties.are reported for the firs. time which reveals.that fluorine bas.d s.rontium s.ries.of perovs.ites.are mechanically s.able and pos.es.weak res.s.ance towards.s.ear deformation as.compared to res.s.ance towards.unidirectional compres.ion while brittlenes. and ionic behavior is.dominated in them which decreas.s.from s.LiF3 to s.RbF3. Calculated cauchy＇s.pres.ure, pois.on＇s.ratio and BIG ratio als. proves.ionic nature in thes. compounds. The pres.nt methodology repres.nts.an effective and influential approach to calculate the whole s.t of elas.ic and mechanical parameters.which would s.pport to unders.and various.phys.cal phenomena and empower device engineers.for implementing thes. materials.in numerous.applications.

关键词： dens.ty functional theory fluoroperovs.ites mechanical properties elas.ic cons.ants