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A Giant Spindle Cell Lipoma of the Parotid-Masseter Lodge (A Case Report)

International Journal of Otolaryngology and Head & Neck Surgery 2021年第4期10卷 251-257页

作者： Siham Mehdaoui Alaoui Adbellatif Oudidi nawal hammas Imane Fadlallah Mohammed Noureddine El Alami El Amine Faculty of Medicine and Pharmacy Sidi Mohammed Ben Abdellah University Fez Morocco Department of Otorhinolaryngology Head and Neck Surgery Hassan II Hospital Fez Morocco Department of Pathology Hassan II Hospital Fez Morocco

Background: The spindle cell lipoma is a rare benign tumor that originated from subcutaneous adipose tissue. It is a slow growing lesion and may become voluminous causing the patient an aesthetic disfigure. The diagnosis is made by the histological examination combined with immunohistochemical analysis. Radiological features present a variety of description because of the proportions difference of spindle cell lipoma components, but imaging is useful to determine the mass extents. The treatment of this kind of benign tumors is surgery which must be completed without need for other therapy. Aim: This case report highlights the exceptional location of spindle cell lipoma in the soft tissues of the parotid-masseter lodge, which may raise differential diagnosis problems with a primary parotid gland tumor. Case Presentation: A 58-year-old man, with no medical history, was presenting a swelling of the parotid region, growing progressively for 6 years, without other associated sign. The patient benefited from a careful physical examination. A computed tomography and magnetic resonance imaging were carried out. Clinical and radiological findings were suggesting a benign tumor occupying the left parotid-masseter lodge. The patient went through a surgical excision of the tumor. Histological and immunohistochemical features revealed a classic shape of spindle cell lipoma. After one year of follow-up, we notice a good recovery without local recurrence. Conclusion: Surgeons and pathologists have to keep in mind the possible development of spindle cell lipoma in any subcutaneous site even if unusual one.

关键词： Spindle Cell Lipoma Parotid-Masseter Lodge Surgery Histology

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Adult Posterior Cranial Fossa Arachnoid Cyst: A Case Report

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Open Journal of Modern Neurosurgery 2019年第4期9卷 436-440页

作者： Ibrahima Berete Alpha Boubacar Bah hammas nawal Mohammed Benzagmout Khalid Chakour Faiz Chaoui Department of Neurosurgery CHU de Donka Conakry Guinea Department of Pathology Hassan II Teaching Hospial Fez Morocco Department of Neurosurgery Hassan II Teaching Hospital Fez Morocco

Adult posterior fossa arachnoid cysts are rare lesions that are considered to be mostly congenital in origin. We present 49-year-old man admitted with a chief complaint of tremor and balance problems for the past 2 months. He had ataxia on examination. Magnetic resonance imaging revealed a well circumscribed midline cystic lesion of the posterior fossa sharing the same signal characteristics as cerebrospinal fluid and non-communicating to the fourth ventricle. He underwent surgical treatment for his symptomatic posterior fossa arachnoid cyst with a good outcome at 2 years follow up.

关键词： Posterior Fossa Arachnoid Cyst Subocciptal Craniotomy Cerebellar Ataxia

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Formation of Natural Melanin/TiO_(2) Nanostructure Hybrids with Enhanced Optical,Thermal and Magnetic Properties as a Soft Material

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Journal of Wuhan University of Technology(Materials Science) 2024年第3期39卷 613-620页

作者： Saja Algessair nawal Madkhali Department of Physics College of ScienceImam Mohammad Ibn Saud Islamic University(IMSIU)P.O.Box 5701Riyadh 11432Saudi Arabia

The natural Melanin/TiO_(2) was synthesized by the use of ultrasonication under UV *** influence of natural melanin on the structural,optical and thermal properties of TiO_(2) nanoparticles was investigated by using Fourier transform infrared spectroscopy,thermogravimetric analysis and UV-Vis *** was observed that incorporating natural melanin on TiO_(2) nanoparticles(TiO_(2)-Mel)occurred at 2.01 eV with a low value of Urbach energy around 100 meV indicating improvement in the crystalline *** measurement at room temperature showed diamagnetic ***,thermal results showed that TiO_(2)-Mel is stable even at temperatures up to 400℃.According to the results obtained by the thermal stability of melanin with titanium dioxide,it can be a good candidate in many applications such as solar cells and optoelectronics.

关键词： natural melanin/TiO_(2) thermal stability optoelectronic nanostructure UV radiation

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Misleading New Entity in Tumors of Kidney: A Case Report and Literature Review

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Open Journal of Urology 2012年第4期2卷 219-222页

作者： El Fatemi Hinde hammas nawal Hafid Imane Tazi Fadl Elfassi Jamal Amarti Afaf Department of Pathology Hassan II Teaching Hospital Fez Morocco Department of Urology Hassan II Teaching Hospital Fez Morocco

Introduction: Mucinous tubular and spindle cell carcinomas (MTSCC's) are recently described rare type of renal cell carcinoma (RCC). They may have morphological similarities to papillary RCC (papRCC) and in our case to carcinoma collecting ducts of Bellini. Case report: We report a rare case of renal tumor, mucinous tubular and spindle cell carcinoma in a 56-year-old woman. The tumor, located in the left kidney, was well circumscribed. MTSCC's are characterized by small, elongated tubules lined by cuboidal cells and/or cords of spindled cells separated by pale mucinous stroma. Discussion: MTSCC is a rare type of renal cell carcinoma. Pathologists should be aware of the histological spectrum of MTSCCs to ensure an accurate diagnosis. Careful attention to the presence of a spindle cell population may be helpful in the differential diagnosis in tumors with predominant compact tubular growth.

关键词： Renal Carcinoma Mucinous Tubular and Spindle Cell Carcinoma CD10 Immunohistochemistry

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Rare Tumors of Ovary: Case Report and Literature Review

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Open Journal of Pathology 2012年第3期2卷 81-84页

作者： El Fatemi Hinde hammas nawal Saadi Hannane Brahmi Sami Amarti Afaf Bannani Abdelaziz Mesbahi Omar Department of Gynecology Hassan II Teaching Hospital Fez Morocco Department of Oncology Hassan II Teaching Hospital Fez Morocco Department of Pathology Hassan II Teaching Hospital Fez Morocco

Introduction: Large cell neuroendocrine carcinoma (LCNEC) or non small cell neuroendocrine carcinoma the ovary is a rare entity and is frequently associated with ovarian surface epithelial tumors. However, its association with serous carcinoma is rarer, in our knowledge tree cases has been described in international literature and the first case in Moroccan literature. Case Report: A 54-year-old woman presented with a pelvic mass measuring 15 cm in diameter. She underwent an exploratory laparotomy with resection of the pelvic mass. Diffuse and nodular intra-abdominal disseminations were observed. Immunohistochemistry stain confirmed the diagnosis of large cell neuroendocrine carcinoma with serous carcinoma. The patient received three courses of carboplatin and paclitaxel and she's still alivewith a decline of 6 months. Its clinicopathologic association is discussed and the literature is reviewed. Conclusion: In summary, ovarian LCNEC is an aggressive tumor with a tendency to present at advanced stage and cause death within a mean of 17 months after diagnosis;however, some patients, particularly those with stage I disease and/or those who have received platinum-based therapy, may have a more favorable prognosis.

关键词： Ovary Neuroendocrine Carcinoma Non-Small Cell Type Serous Carcinoma Immunohistochemistry

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Lipomatous Medulloblastoma: A Case Report

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Open Journal of Modern Neurosurgery 2019年第4期9卷 452-456页

作者： Ibrahima Berete Alpha Boubacar Bah Seylan Diawara hammas nawal Mohammed Benzagmout Khalid Chakour Mohammed Faiz Chaoui Department of Neurosurgery University Hospital Donka Conakry Guinea Department of Pathology University Hospital Hassan II Fez Morocco Department of Neurosurgery University Hospital Hassan II Fez Morocco

Lipomatous medulloblastoma is not a separate entity but apparently distinct variant of medulloblastoma. Since the first case report in 1978 by Bechtel et al. [1], few cases have been published. We report an additional case of a 52-year-old right-handed man presented to the emergency department with evaluation of progressive severe intracranial hypertension and ataxia. His past medical history was unremarkable. His physical examination showed cerebellar syndromes. He underwent magnetic resonance imaging (MRI) which revealed a unique mass in the posterior fossa, lying within a cerebellar hemisphere. The patient underwent a suboccipital craniotomy for with a complete resection and samples were sent for histologic examination, showing closely packed, and round to oval cells. The nuclei had an irregular shape with clumps of heterochromatin. Lipid accumulation was a prominent feature of neoplastic cells. Postoperatively the patient did not receive fractionated radiotherapy. He is alive without deficit and with no evidence of recurrence on neuroimaging.

关键词： Medulloblastoma Lipomatous Liponeurocytoma Posterior Fossa Tumor Suboccipital Craniotomy

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Scrotal Skin Metastases of Renal Cell Carcinoma: A Case Report

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Case Reports in Clinical Medicine 2015年第3期4卷 93-96页

作者： Khadija Benhayoune Hinde El Fatemi Jamal El Fassi Soufiane Mellas Hassan Farih Laila Chbani nawal hammas Taoufiq Harmouch Laboratory of Surgical Pathology CHU Hassan II Fez Morocco Department of Urology CHU Hassan II Fez Morocco

Cutaneous metastasis from renal cell carcinoma is believed to be rare. We present a 66-year-old man operated for kidney cancer 20 years ago and has consulted for a scrotal lesion that had started 20 days. The physical examination revealed an erythematous lesion. A biopsy of the scrotal skin was made. We found a scrotal metastasis of renal cell carcinoma.

关键词： Scrotal Skin Renal Cell Carcinoma Metastasis 20 Years

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Post Traumatic Diaphragmatic Hernia Revealing a Colonic Tumor

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Open Journal of Thoracic Surgery 2016年第3期6卷 13-17页

作者： Mohammed Elkehal Sani Rabiou Boubacar Efared Saad Slaiki Hicham Elbouhadouti Yassine Ouadnouni nawal hammas Taoufiq Harmouch Mohamed Smahi Department of Visceral Surgery Hassan II University Hospital Fez Morocco Department of Thoracic Surgery Hassan II University Hospital Fez Morocco Department of Cyto-Pathology Hassan II University Hospital Fez Morocco Faculty of Medicine and Pharmacy Sidi Mohamed Benabdellah University Fez Morocco

Post traumatic diaphragmatic injuries have long been known. However their varied clinical, expressions lead to difficulties which cause its delay. The occurrence of herniation of hollow viscera in the thoracic cavity followed by its necrosis or perforation, is a delayed complication, a rare entity with a poor prognosis. The discovery of a colonic tumor in a diaphragmatic hernia is an exceptional clinical circumstance. Here we report the case of a patient with a complicated diaphragmatic hernia, whose symptoms are precipitated by the presence of a colon stenosing tumor. The management consisted of an exclusive laparotomy had allowed dealing in one surgical intervention with both the abdominal and thoracic injuries.

关键词： Diaphragmatic Hernia Gastrointestinal Tumor Surgery

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Cognitive Disorders, Depression and Anxiety in Temporal Lobe Epilepsy: An Overview

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Journal of Biosciences and Medicines 2024年第3期12卷 77-93页

作者： Amina Tani nawal Adali REGNE Research Laboratory Faculty of Medicine and Pharmacy Agadir Morocco ENSA Ibn Zohr University Agadir Morocco Neurology Department University Hospital Agadir Morocco

Partial epilepsies, originating in a specific brain region, affect about 60% of adults with epilepsy. Temporal lobe epilepsy (TLE) is the most prevalent subtype within this category, often necessitating surgical intervention due to its refractoriness to antiepileptic drugs (AEDs). Hippocampal sclerosis, a common underlying pathology, often exacerbates the severity by introducing cognitive and emotional challenges. This review delves deeper into the cognitive profile of TLE, along with the risk factors for cognitive disorders, depression, and anxiety in this population.

关键词： Temporal Lobe Epilepsy Cognitive Disorders Anxiety Depression

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Global multifaceted biodiversity patterns,centers,and conservation needs in angiosperms

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Science China(Life Sciences) 2024年第4期67卷 817-828页

作者： Ao Luo Yaoqi Li nawal Shrestha Xiaoting Xu Xiangyan Su Yichao Li Tong Lyu Kilara Waris Zhiyao Tang Xiaojuan Liu Luxiang Lin Yongsheng Chen Kuiling Zu Wenqi Song Shijia Peng Niklaus E.Zimmermann Loïc Pellissier Zhiheng Wang Institute of Ecology and Key Laboratory for Earth Surface Processes of the Ministry of Education College of Urban and Environmental SciencesPeking UniversityBeijing 100871China Department of Health and Environmental Sciences Xi’an Jiaotong-Liverpool UniversitySuzhou 215123China State Key Laboratory of Grassland Agro-Ecosystems College of EcologyLanzhou UniversityLanzhou 730000China Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education College of Life SciencesSichuan UniversityChengdu 610065China Land Consolidation and Rehabilitation Center Ministry of Natural ResourcesBeijing 100035China State Key Laboratory of Vegetation and Environmental Change Institute of BotanyChinese Academy of SciencesBeijing 100093China CAS Key Laboratory of Tropical Forest Ecology Xishuangbanna Tropical Botanical GardenChinese Academy of SciencesKunming 650201China Swiss Federal Research Institute WSL Birmensdorf 8903Switzerland Department of Environmental Systems Science ETH ZürichZürich 8092Switzerland

The Convention on Biological Diversity seeks to conserve at least 30%of global land and water areas by 2030,which is a challenge but also an opportunity to better preserve biodiversity,including flowering plants(angiosperms).Herein,we compiled a large database on distributions of over 300,000 angiosperm species and the key functional traits of 67,024 *** this database,we constructed biodiversity-environment models to predict global patterns of taxonomic,phylogenetic,and functional diversity in terrestrial angiosperms and provide a comprehensive mapping of the three diversity *** further evaluated the current protection status of the biodiversity centers of these diversity *** results showed that geographical patterns of the three facets of plant diversity exhibited substantial spatial mismatches and nonoverlapping conservation *** centers of functional diversity,particularly of herbaceous species,were primarily distributed in temperate regions and under weaker protection compared with other biodiversity centers of taxonomic and phylogenetic *** global assessment of multifaceted biodiversity patterns and centers highlights the insufficiency and unbalanced conservation among the three diversity facets and the two growth forms(woody ***),thus providing directions for guiding the future conservation of global plant diversity.

关键词： angiosperms species richness phylogenetic diversity functional diversity plant traits woody species herbaceous species

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